Clinical trials: Edentulous Mouth
Edentulous Alveolar Ridge
Soft and Hard Tissue Changes Around Implants
Our long-term goal is to generate evidence for the creation of successful implant restorations and ideal supporting tissues in adequate health by utilizing patient-tailored implant protocols such as the use of customized…
- Trial name
- NCT05769673
- Testing
- Placement of dental implant, Placement of stock healing abutment, Placement of customized CAD/CAM healing abutment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Edentulous; Alveolar Process, Atrophy
Reliability of All on 4 Using 2 Zygomatic and 2 Conventional Implants vs All on 4 Implants for Rehabilitation of Maxilla
Oral rehabilitation by dental implants in the severely atrophic maxilla often represents a challenge. To overcome this difficulty, bone augmentation procedures such as sinus augmentation, guided bone regeneration (GBR), or…
- Trial name
- NCT05108324
- Testing
- zygomatic implant, conventional implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Extraction Status Nos, Edentulous Alveolar Ridge
3D Radiographic Evaluation of a Novel Implant Site Development Technique
The present retrospective study aims at assessing the clinical effects of a novel implant site development (Extraction site development - XSD) technique after tooth extraction compared with extraction alone in patients requiring…
- Trial name
- NCT02660697
- Testing
- Extraction site development
- Where
- Hungary
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Compare the Difference in Occlusal Force Distribution and Denture Retention Using 2 Different Denture Base Materials in Implant Retained Overdenture
The global increase in the aging population has led to a rise in total edentulism, which remains a major public health concern. two-implant-retained mandibular overdentures have been regarded as the standard of care, offering…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT07250503
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Maxillary Class III Modification I Edentulous Patients
Muscle Activity Evaluation of Maxillary Bilateral Bounded Partial Denture Fabricated By Bre-Flex Versus Peek
Evaluation of the muscle activity of masseter in tooth borne partial denture wearers (class III modification 1 Kennedy's classification) with two different denture base materials (Breflex and PEEK) by means of electromyograph.
- Trial name
- NCT03507153
- Testing
- Bre-flex maxillary partial denture, PEEK maxillary partial denture
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Edentulous
Multicenter Study of Denture Adhesive
To establish evidence based guidelines for denture adhesives (powder and cream), multicenter cross over randomized clinical trial will be carried out.
- Trial name
- DAG (NCT01712802)
- Testing
- Denture Adhesives: Cream, Denture Adhesives: Powder, Saline
- Where
- Japan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nihon University
Edentulous, Bone Resorption
Platform Switched Implant and Bone Level Alteration
This is a two-year prospective randomized clinical study to to evaluate whether the gingival thickness and insertion depth of dental implants have any influence on marginal bone levels changes around platform switched implants.
- Trial name
- NCT02867982
- Testing
- Subcrestal implant placement, Paracrestal implant placement, prophylactic antibiotics
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Beijing University Health Science Center
Edentulous Alveolar Ridge, Bone Atrophy, Alveolar
Crestal vs Lateral Sinus Lift Augmentation
The aim of this randomised controlled trial (RCT) of split-mouth design was to compare patient preference and effectiveness of two different techniques for lifting the maxillary sinus: the crestal approach versus the lateral…
- Trial name
- NCT04111250
- Testing
- Maxillary sinus augmentation
- Where
- Albania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Single Tooth Lost, Partially Edentulous Maxilla
Accuracy of Trephination-based Versus Drilling-based Guided Dental Implant Placement
This study will be initiated to compare the accuracy of implant placement using the guided trephination drilling protocol and the guided conventional drilling protocol.
- Trial name
- NCT05295082
- Testing
- guided trephination-based drilling protocol, guided Conventional drilling-based protocol
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mohammed Ramadan
Jaw, Edentulous, Partially
Fully Guided Versus Conventionally Guided Implant Placement by Dental Students
Patients where placement of a single implant will be treated by senior dental students under close supervision of experienced spcialists.
- Trial name
- NCT04546269
- Testing
- Fully-guided vs. conventionally guided implant placement
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Completely Edentulous
Prosthetic Maintenance of Two Implant-Retained Overdentures Reinforced With PEKK Versus Co-Cr Frameworks
The goal of this randomized clinical trial is to compare and assess the prosthetic maintenance of two implant-retained mandibular overdentures reinforced with PEKK and Co-Cr frameworks after twelve months.
- Trial name
- NCT06219811
- Testing
- Two implant -retained overdenture reinforced with Co-Cr framework, Two implant -retained overdenture reinforced with PEEK framework
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Implant Complication
Prosthetic and Biological Complications of Implant Supported Prostheses
complications of implant retained prostheses
- Trial name
- NCT05297253
- Testing
- telescopic overdenture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Edentulous Maxilla
Clinical Study Investigating the Efficiency and Complications Related to Two Different Procedures Used for the Preparation of Dentures Applied in Patients With Edentulous
The principal aim of the study is to evaluate the prosthetic complications with CAD-CAM fabricated provisional prostheses and denture conversion prostheses after 3 months of function.
- Trial name
- NCT05332977
- Testing
- CAD-CAM fabricated provisional prosthesis, DC (denture conversion) provisional prosthesis
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Single Edentulous Space
Fabrication of a Definitive Cad/Cam Titanium Abutment Prior to Guided Surgery: a Pilot Study.
The study will involve placing a dental implant through a guided surgery protocol developed using 3D CT technology. Because the implant position is planned digitally using the CT data from the patient, this allows investigation…
- Trial name
- NCT02218541
- Testing
- abutment margin 0.5 mm subgingival, abutment margin 1.5 mm subgingival
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Jaw, Edentulous, Jaw, Edentulous, Partially
Prospective Neodent® Zirconia System Study
The Neodent® Zirconia Implant is designed for the treatment of oral endosteal implantation for the functional and aesthetic rehabilitation, allowing for treatment of patients with different bone qualities.
- Trial name
- NCT04545840
- Testing
- Dental Implants
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Neodent
Partially Edentulous Mandible
Evaluation of Occlusal Contact Distribution in Digitally Fabricated Implant-Retained Fixed Partial Dentures in Mandibular Kennedy Class II Patients Following Artificial Intelligence Bite Optimization: A Quasi-Experimental Study
The aim of the study is to evaluate the occlusal contact distribution in digitally fabricated implant-retained fixed partial dentures in mandibular Kennedy Class II patients before and after artificial intelligence bite…
- Trial name
- Quasi (NCT07657910)
- Testing
- After, Before
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Edentulous; Alveolar Process, Atrophy, Healthy Adult Participants
Comparison of Nd Yag, Diode and Er:YAG Lasers vs Scalpel in Preprosthetic Vestibuloplasty: Vestibular Depth Gain
The aim of this study was to compare the clinical results obtained using the conventional approach versus the modern laser method, by recording postoperative results
- Conditions
- Edentulous; Alveolar Process, Atrophy, Healthy Adult Participants, Edentulous Alveolar Ridge With Labial Resorption
- Trial name
- 78/30102018 (NCT07462117)
- Testing
- vestibuloplasty for Nd-YAG group, diode vestibuloplasty, Er-YAG laser vestibuloplasty
- Where
- Romania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Edentulous Mouth, Periodontal Diseases
Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement
The objectives of this study are to analyze the oral microbiome modulations occurring during the transition from partial (with some residual teeth) to full edentulous (without remaining teeth) status and implant placement in…
- Conditions
- Edentulous Mouth, Periodontal Diseases, Periodontitis, Adult, Microbial Colonization
- Trial name
- NCT06149585
- Testing
- Microbial Sampling
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Edentulous
The Treatment of Implant-retained Mandibular Overdentures for Edentulous Patients
The purpose of this study is to investigate to what extent IOs improve the functionality of edentulous patients and changes in quality of life and overall patient satisfaction following treatment with IOs.
- Trial name
- TIMOEP (NCT02846805)
- Testing
- implant-retained overdentures
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chufan Ma