Clinical trials: Effect Increased
Effect Increased
Can Latency of Action in Infraclavicular Brachial Plexus Block be Shortened With Warmed Bupivacaine?
Brachial plexus blocks have some advantages, but also have some disadvantages as well. As with all nerve blocks, having to wait sometime for an effective block, sometimes failure to achieve an adequate block and possible…
- Trial name
- NCT03346993
- Testing
- Bupivacaine Hydrochloride 5 MG/ML
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Palandöken State Hospital
Hypertension, Diet, Healthy
eCulinary Medicine Emphasizing Herbs/Spices to Increase Vegetable Intake
e-Culinary medicine emphasizes on herbs and spices, will increase consumption of vegetables and reduce sodium in the diets of people with hypertension and lead to a more favorable health profile.
- Conditions
- Hypertension, Diet, Healthy, Culinary Medicine
- Trial name
- NCT05587855
- Testing
- E-group
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Texas Tech University
Healthy
Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin
To investigate the mutual interaction potential of digoxin, furosemide, metformin, and rosuvastatin when given alone or together as a cocktail, and to investigate the effect of high doses of metformin or furosemide on…
- Trial name
- NCT02231931
- Testing
- Digoxin, Rosuvastatin, Digoxin, Furosemide, Metformin hydrochloride, Rosuvastatin
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Neurocysticercosis
Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients
The purpose of this study is to determine whether a short course of increased corticosteroid dosing with tapered dosing decreases seizure frequency as compared to standard corticosteroid dosing in patients with neurocysticercosis…
- Trial name
- NCT00290823
- Testing
- Albendazole, Dexamethasone, Omeprazole
- Where
- Peru
- Volunteers
- 110 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gastric Adenocarcinoma, Gastric Squamous Cell Carcinoma
Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer
This phase II trial studies how well pembrolizumab and palliative radiation therapy works in treating patients with esophagus, stomach, or gastroesophageal junction cancer that has spread to other parts of the body.
- Conditions
- Gastric Adenocarcinoma, Gastric Squamous Cell Carcinoma, Gastroesophageal Junction Adenocarcinoma, Metastatic Malignant Neoplasm in the Stomach
- Trial name
- NCT02830594
- Testing
- External Beam Radiation Therapy, Laboratory Biomarker Analysis, Pembrolizumab
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- City of Hope Medical Center
Breast Cancer, Anxiety
AR Health Education Video for Postoperative Breast Cancer Patients
Breast cancer surgery patients may experience anxiety and depression before and after surgery. Health education can help patients understand the surgical process and postoperative care, but traditional education may not always be…
- Conditions
- Breast Cancer, Anxiety, Depression
- Trial name
- AR-BCS (NCT07604389)
- Testing
- Augmented Reality Health Education Video, Routine Health Education
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Breast Cancer
Effect of Increased Light Exposure on Fatigue in Breast Cancer
Patients treated with chemotherapy complain of poor sleep, fatigue and depression. In addition, chemotherapy disrupts the body's internal "biological clock", which may make sleep, fatigue and depression all worse.
- Trial name
- NCT00478257
- Testing
- bright white light, comparator red light treatment
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Diego
Healthy
Effects of Ethanol on Intestinal Permeability and Integrity
Alcohol consumption is a major health problem worldwide. It affects all systems of the body especially the gastrointestinal tract.
- Trial name
- NCT00928733
- Testing
- Gastroduodenoscopy- Intraduodenal intubation
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Infertility
Effect of Low Level Laser Therapy on Endometrial Cells: An In Vitro Study
The human endometrium is an extremely sensitive target. LLLT can enhance the proliferation rate of various cell lines, it produces higher rates of ATP, RNA, and DNA synthesis in stem cells and other cell lines.
- Trial name
- LLLT (NCT02764034)
- Testing
- Low level Laser diode machine
- Where
- Egypt
- Sponsor
- Cairo University
Intracranial Pressure Increase
Effect of Acetazolamide on Optic Nerve Sheath Diameter in Laparoscopic Donor Nephrectomies
The purpose of the trial is to study the effect of acetazolamide administered via Ryle's tube on optic nerve sheath diameter in laparoscopic live donor nephrectomy patients.
- Trial name
- NCT03005665
- Testing
- Acetazolamide, Normal Saline
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Augmented Reality
AR vs In Person Simulation for Medical Workplace Training
This study will evaluate the physiologic and emotional effects of an augmented reality (AR) simulation versus an in-person simulation. This is a single institution, non-inferiority, randomized controlled trial.
- Trial name
- NCT05674188
- Testing
- Augmented Reality Headset
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lung Cancer Patients
Effect of Mobile Augmented Reality Counseling on Improving Shared Decision-Making in Thoracic Surgery
This randomized clinical trial evaluates the effectiveness of Mobile Augmented Reality (MAR) counseling compared to traditional verbal counseling for patients undergoing thoracic surgery.
- Trial name
- NCT07062393
- Testing
- Traditional Counseling → MAR Counseling, MAR Counseling → Traditional Counseling
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- Tri-Service General Hospital (TSGH)
HIV
Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine
The purpose of this study is to investigate if B vitamin substitution have effect on NFL (neurofilament light protein) plasma levels and neurocognitive performance in HIV-infected individuals with increased plasma homocysteine
- Trial name
- NCT02773147
- Testing
- Cyanocobalamin, Folate, Pyridoxine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Osteopenia
The Effect of Semaglutide on Bone Turnover in Patients With Increased Risk of Bone Fracture
The hypothesis for this study is that the GLP-1Ra Semaglutide has a positive effect on the balance between build-up and degradation as well as the strength of the bones in men and women aged 40-85 years at increased risk of bone…
- Trial name
- NCT04702516
- Testing
- Ozempic
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Morten Frost
Infection, Human Immunodeficiency Virus
A Study to Assess the Effect of High Fat Meal and Increased Gastric pH on the Bioavailability of an Extended Release Formulation of BMS-663068 in Healthy Subjects
The purpose of this study is to estimate the effect of high fat meal and increased gastric pH on BMS-663068 bioavailability
- Trial name
- NCT02666053
- Testing
- BMS-663068
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Cardiovascular Risk Factor
Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients
This is a prospective randomised trial investigating the effect of a preemptive administration of levosimendan on postoperative cardiac NT-proBNP concentrations.
- Trial name
- IMPROVE (NCT04329624)
- Testing
- Levosimendan
- Where
- Austria
- Volunteers
- 230 people
- Sponsor
- Medical University of Vienna
Cryotherapy Effect
Cooling Induces Motor Facilitation With Sympathetic Activation
Cryotherapy has beneficial effects such as motor facilitation, increase isometric force generation, and reduce spasticity. It is known that the muscle spindle has sympathetic innervation.
- Trial name
- NCT05832970
- Testing
- Brief skin cooling
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Effects of Anesthesia Spinal and Epidural in Pregnancy
The Relationship Between Perfusion Index and Pleth Variability Index and Hemodynamics in Spinal Anesthesia
In routine practice, the preferred anesthesia method in cesarean section operations is spinal anesthesia, but it causes hypotension in a significant part of the patients.
- Trial name
- NCT05174260
- Testing
- perfusion index, pleth variable index
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Adiyaman University
Hyperalgesia
Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids
This research study explores whether a beta-blocker (propranolol) can prevent a person from becoming more sensitive to pain after administration of an opioid (remifentanil).
- Trial name
- NCT01222091
- Testing
- Propranolol, Remifentanil
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Prediabetic State, Dysglycemia
Mode of Action (MoA) Study of TOTUM-63 in Individuals at Increased Cardio-metabolic Risk
This clinical study aims to investigate the effects of TOTUM-63, a mix of 5 plant extracts, consumed at the daily regimen of three times per day, on cardiometabolic health and gut microbiota profile in overweight-obese…
- Conditions
- Prediabetic State, Dysglycemia, Overweight and Obesity
- Trial name
- NCT05369585
- Testing
- TOTUM-63
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Valbiotis