Clinical trials: Effect Increased
Breast Cancer
Protocol for Women at Increased Risk of Developing Breast Cancer
A pilot study to assess the effects of six months of letrozole on breast tissue risk markers in postmenopausal women on hormone replacement therapy at high risk of developing breast cancer.
- Trial name
- NCT00291135
- Testing
- letrozole
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Carol Fabian, MD
Randomised Controlled Trial, Public Health Nursing
Program to Increase Fathers' Involvement in Infant Care
Fathers participating in the study will be given an 8-week formality intervention. Participants will be shown 4-week infant care training records and then 4-week videos prepared on educational topics.
- Conditions
- Randomised Controlled Trial, Public Health Nursing, Child Health
- Trial name
- Infant Care (NCT06969248)
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Hypertension, Dyslipidemia
Effect of Omega 3 in Hypertensive Patients
This study aims to evaluate the impact of omega-3 (O3) supplementation in participants with high blood pressure and elevated triglycerides, focusing on cardiovascular risk factors.
- Trial name
- OMECARDIO (NCT06840964)
- Testing
- omega 3 ethyl esters at 90%
- Where
- Argentina
- Volunteers
- 100 people
- Sponsor
- Santa Maria de la Salud, Argentina
Periodontal Intrabony Defects
Effects of Modified Minimally Invasive Surgical Technique With Clindamycin Augmented Platelet-rich Fibrin Versus Platelet-rich Fibrin Alone for Management of Periodontal Intrabony Defects.
Periodontal infections in the oral cavity are strongly associated with clinical outcomes of both regenerative and conventional surgical procedures and should receive proper attention.
- Trial name
- NCT05177198
- Testing
- M-MIST + Clindamycin augmented PRF, M-MIST + PRF
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malnutrition, Child
Cash Transfers to Increase Dietary Diversity in Grand Gedeh County, Liberia
The investigators aim to evaluate the efficacy of a cash transfer and nutrition education program delivered by community health assistants to increase dietary diversity among children 6 to 23 months of age in Grand Gedeh County…
- Trial name
- NCT04101487
- Testing
- Cash Transfer, Cash Transfers and Nutrition Education
- Where
- Liberia
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Breast Cancer
Exemestane in Reducing Breast Density in Postmenopausal Women at Risk for Breast Cancer
RATIONALE: High estrogen levels may be associated with dense breast tissue and an increased risk of developing breast cancer. Exemestane may be effective in preventing the development of breast cancer by decreasing estrogen…
- Trial name
- NCT00066586
- Testing
- exemestane
- Where
- 12 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- NCIC Clinical Trials Group
Cholecystectomy
Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil
Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain [hyperalgesia] appears.
- Trial name
- NCT06473896
- Testing
- Ketalar, Dexmedetomidine
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Assaf-Harofeh Medical Center
Clopidogrel Non-Responsiveness
The Comparison of Effects Between Increased Dose of Clopidogrel and Addition of Cilostazol
To compare the effect of increased dosing of clopidogrel and adding cilostazol to standard dose of clopidogrel after the insertion of drug-eluting stent in patients with clopidogrel resistance
- Trial name
- 4C-DES (NCT00620646)
- Testing
- aspirin, clopidogrel, aspirin, clopidogrel, cilostazol
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Water Consumption, Drinking Behavior
Effects of a School-based Intervention to Increase the Water Consumption in Elementary School Children
The purpose of this controlled intervention study is to evaluate the effectiveness of a school-based intervention aiming at increasing the water consumption in elementary school children.
- Trial name
- H2NOE (NCT03852173)
- Testing
- Wasserschulen
- Where
- Austria
- Volunteers
- 1,485 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Healthy
The Effect of Portable AR on Tooth Brushing Skill for Elementary School Students
The aim of this study An augmented reality (AR) simulation toothbrushing machine was developed to train proper brushing technique for children.
- Trial name
- NCT05956262
- Testing
- AR-toothbrush machine, Teach proper brushing skills
- Where
- Taiwan
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Insufficient Breastmilk Production
Effectiveness of Domperidone to Increase Breastmilk Supply in Mothers With Low Supply
This study is testing if a medication called domperidone will help women produce more milk so that they can keep breastfeeding and not use formula.
- Trial name
- NCT00284024
- Testing
- domperidone
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Pre-diabetic
Investigation of the Ability of a Supplement to Increase Good Bacteria in the Human Intestine and Blood Sugar Levels
This study aims to determine whether the use of a supplement called xylooligosaccharide (XOS) increases the number of good bacteria that live in human intestines and can maintain healthy blood sugar levels, and whether XOS has…
- Trial name
- XOS2 (NCT01944904)
- Testing
- Sugar Pill, XOS 2.8
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Inactivity/Low Levels of Exercise
My Exercise. A Team-based Workplace Intervention for Increased Exercise
The aim of this research study is to assess the effectiveness of an intervention on exercise and health, and to contribute to the understanding of how team-based worksite health promotion programs should be designed in order to…
- Trial name
- Myexercise (NCT02429635)
- Testing
- My exercise
- Where
- Norway
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Polycystic Ovary Syndrome
Effect of Increased Circulating Androgens on Granulosa Cell Responses to FSH.
The purpose of this study is to evaluate the effect of increased circulating androgens on estradiol production by the granulosa cells in response to FSH stimulus.
- Trial name
- NCT02389088
- Testing
- Letrozole
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Physician Education
A Phase 4 Study of Regorafenib in Metastatic Colorectal Cancer - Does Educating Physicians Change Patient Outcomes?
Randomized trial to evaluate impact of healthcare provider( clinician and nursing staff) support and education on treatment discontinuation rates in the absence of progression in patients with metastatic colorectal cancer treated…
- Trial name
- SMART (NCT02287025)
- Testing
- Regorafenib (Stivarga, BAY73-4506), iPAD application, Bayer specialist
- Where
- 17 sites in United States
- Volunteers
- 23 people
- Sponsor
- Bayer
Type 2 Diabetes Mellitus, Insulin Resistance
Impact of Overfeeding and Following Exercise Training in Individuals With and Without Increased Risk of Type 2 Diabetes
Low birth weight (LBW), a marker of impaired fetal growth is an independent and strong risk factor for type 2 diabetes (T2D). A western lifestyle characterized by a surplus of calories, and/or a low physical activity level…
- Conditions
- Type 2 Diabetes Mellitus, Insulin Resistance, Dyslipidemia
- Trial name
- NCT02982408
- Testing
- High carbohydrate overfeeding, Exercise, Normal physical activity
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Venous Thrombosis
Vasculaire Compression System Increases Flow Velocity in the Femoral Vein
The objective of this clinical study was to demonstrate the performance of the Vasculaire Compression System to increase femoral venous peak velocity (PFV) in healthy subjects.
- Trial name
- NCT01240330
- Testing
- Pneumatic Compression therapy
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Venous Health Systems, Inc.
Eating Behavior, Obesity
Effect of Gut-Cued Eating on BMI and Efficacy of Open-Label Placebo to Augment Weight Loss
The study will assess the effect of attending to stomach-cues of hunger and fullness on body weight and any additional benefit provided by open-label placebo.
- Conditions
- Eating Behavior, Obesity, Body Weight, Hunger
- Trial name
- GCE (NCT03850990)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Back Pain, Instability Lumbar Spine
Relative Stiffness of Lumbar Spine and Hamstrings Muscle Stretching
The purpose of this study is to investigate the effect of lumbopelvic stabilization on hamstrings muscle stretching in individuals with history of low back pain suspected to have a clinical lumbar instability.
- Conditions
- Back Pain, Instability Lumbar Spine, Muscle Tightness
- Trial name
- NCT03787979
- Testing
- Lumbopelvic stiffening technique, Lumbopelvic relaxing technique
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln