Clinical trials: Effect Neonatal
Methamphetamine Abuse, Newborn Complication | Patient | Neonatalology
Cardiovascular Effects of Prenatal Methamphetamine Exposure
Methamphetamine (MA) is one of the commonly used drugs during pregnancy. Cardiovascular effects of MA include elevated blood pressure, acute vasospasm, atherosclerotic disease, structural and electrical remodeling of cardiac…
- Trial name
- NCT04616625
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Port-Wine Stain
Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ Laser.
Two limitations of single pulse, laser treatment of port-wine stains (PWS) are: (i) hemorrhage and purpura which may lead to post-treatment pigmentation and (ii) the necessity for repeated treatment sessions.
- Trial name
- NCT04103164
- Testing
- Cutera excel V™ Laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Psychological Well-being, Childbirth
Supportive Care During Childbirth and Well-being
The aim of this study is to evaluate the effects of continuous supportive care (ICSC) at birth on some parameters of maternal psychological well-being.
- Conditions
- Psychological Well-being, Childbirth, Care Pattern, Maternal
- Trial name
- NCT05333653
- Testing
- Continouse supportive care, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mersin University
Pregnancy Complications, Pregnancy, High Risk
Active Pregnancy Against COVID-19
Historically and traditionally, the recommendations related to physical exercise during pregnancy have been based more on moral or cultural issues than on scientific evidence.
- Conditions
- Pregnancy Complications, Pregnancy, High Risk, Pregnancy Induced Hypertension, Newborn Morbidity
- Trial name
- ACPREGCOV (NCT04563065)
- Testing
- Exercise program, Healthy lifestyle advise
- Where
- 2 sites in Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Infantile Colic, Reflexology
The Effect of Foot Reflexology on Infantile Colic Symptoms
Aim: To compare the effect of foot reflexology and placebo foot reflexology on colic symptoms such as pain, ineffective sleep, and colicky crying periods in infants with colic.
- Trial name
- NCT03939611
- Testing
- Foot Reflexology
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Usher Syndrome Type 3
BF844 Safety and Pharmacokinetic Study in Healthy Volunteers
First-in-Human Phase-1 Clinical Trial to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Ascending Doses of BF844 when Administered Orally to Healthy Adult Participants.
- Trial name
- NCT06592131
- Testing
- BF844
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- EyeXCel Pty. Ltd.
Pain
The Effect of Warming and Vibration Applications on Pain in Newborns
This study aimed to determine the effects of warming and vibration applications on pain during heel blood collection in newborns. H1: Warming application has a positive effect on pain during heel blood collection in newborns.
- Trial name
- NCT06607575
- Testing
- Control group, Warming, Vibration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Labor; Forced or Induced, Affecting Fetus or Newborn
The Effects of Increased IV Hydration on Nulliparous Women Undergoing an Induction of Labor
The objective of this study is to compare the effects of intravenous fluid rate on the course of labor in nulliparous patients who are undergoing labor induction and have an unfavorable cervix.
- Trial name
- NCT02989571
- Testing
- Intravenous normal saline administered at 250ml/hr, Intravenous normal saline administered at 125ml/hr
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Friedreich Ataxia
Evaluation of the Effects of Calcitriol's in the Neurological Symptoms of Friedreich's Ataxia Patients
Friedreich's Ataxia (FA) is an autosomal recessive disease the mutation of which leads to a deficiency of a protein called frataxin, which is responsible for the symptoms of the disease.
- Trial name
- CalcitriolFA (NCT04801303)
- Testing
- Calcitriol, Blood analysis for frataxin's level measurement, Blood analysis for hypercalcemia's control
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Berta Alemany
Abdominal Pain, Abdominal Cramps
A Study on Intestinal Gas Symptoms to Evaluate the Effects of Gas Defense in Otherwise Healthy Adult
This is a randomized, double-blind, placebo-controlled trial to determine the safety and efficacy of Digestive Advantage™ Gas Defense formula, a probiotic dietary supplement.
- Conditions
- Abdominal Pain, Abdominal Cramps, Flatulence
- Trial name
- NCT00881322
- Testing
- BC-130 (Gas Defense)
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Miami Research Associates
Body Mass Index Quantitative Trait Locus 5 Disorder, Tangier Disease
Effect of High Protein Diet on Adiponectin and Inflammation Among Overweight and Obese Children
The investigators aimed to determine the effects of HP diet on adiponectin and inflammatory factors among overweight and obese children.
- Trial name
- NCT01886495
- Testing
- nutrition intervention
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Digestive Health, Quality of Life
Protein-Prebiotic Wellbeing Study
Healthy participants with self-reported GI complaints will consume the protein supplement that they normally use for recovery purposes after exercise during a 3-week baseline period, followed by a 3-week intervention period in…
- Trial name
- NCT05303753
- Testing
- fermented dairy protein with prebiotic fiber
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Arizona State University
MIH, Molar-Incisor Hypomineralization
Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia in MIH-Affected Molars
Molar-incisor hypomineralization (MIH) is a developmental enamel defect of unclear etiology that affects permanent first molars and often permanent incisors, leading to increased porosity, hypersensitivity, and poor prognosis.
- Conditions
- MIH, Molar-Incisor Hypomineralization, Caries Assessment
- Trial name
- NCT07326241
- Testing
- Standard Local Anesthesia, Intraoral Cryotherapy, Silver Diamine Fluoride (SDF)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Preterm, Nursing Caries
The Effect of Positions on Physiological Parameters of Preterm Neonates Receiving Mechanical Ventilation
This study was planned as an experimental study with a randomized crossover design to determine the effect of supine, prone, right lateral, left lateral, and quarter prone positions used during daily routine care in the neonatal…
- Trial name
- NCT05509621
- Testing
- The Effect of Supine Position on Physiological Parameters in Mechanically Ventilated Preterm Newborns, The Effect of Prone Position on Physiological Parameters in Mechanically Ventilated Preterm Newborns, The Effect of left lateral Position on Physiological Parameters in Mechanically Ventilated Preterm Newborns
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Neonatal Morbidity, Neonatal Illnesses
Effect of Referral Card on Neonatal Medical Care Seeking for Institutional Births in Urban Lucknow
Neonatal mortality rate in Uttar Pradesh, Northern India is 53.6 per thousand, and accounts for 8% of global neonatal deaths.It has been argued that prompt and appropriate care-seeking for sick neonates can substantially reduce…
- Trial name
- Referral Card (NCT00832143)
- Testing
- Referral Card with one-to-one counseling
- Where
- India
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- King George's Medical University
Congenital Heart Disease, Single Ventricle
Cardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise Training
Introduction: The Fontan operation is the surgical treatment in most patients with either anatomic or functional single ventricles.
- Conditions
- Congenital Heart Disease, Single Ventricle, Univentricular Heart
- Trial name
- NCT02283255
- Testing
- Aerobic Exercise Training, Inspiratory Muscle Training, No Exercise Training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Breastfeeding
The Effect of Early Skin-to-skin Contact on Initiation of Breastfeeding, Newborn Temperature and Duration of Third Stage of Labor
Background: Keeping mother and newborn skin-to-skin contact (SSC) after birth brings about numerous protective effects; however, it is an intervention that is underutilized in Iraq where a globally considerable rate of maternal…
- Trial name
- NCT03548389
- Testing
- Skin to skin contact
- Where
- Iraq
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Down Syndrome
Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound Exercises
This randomized clinical trial investigates the comparative effects of Cuevas Medak Exercises Vs Rebound Exercises on physical fitness in DS.
- Trial name
- DownSyndrome (NCT07248449)
- Testing
- Cuevas Medak Exercises
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Reproductive Effects, Pregnancy
Vitamin D and Pregnancy: Camden Study
Vitamin D is present in food either naturally or by fortification and included in nutritional supplements. It is also synthesized photochemically by the skin from ultraviolet B radiation.
- Trial name
- NCT02032459
- Where
- United States
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- Rowan University
Digestive Health, Quality of Life
Effect of a Fermented Dairy Protein With Prebiotic Fiber on GI Complaints
A positive impact of a fermented dairy protein with prebiotic fiber supplement on self-reported GI complaints and wellbeing has been suggested (Wardenaar et al. 2024).
- Trial name
- NCT06946017
- Testing
- Fermented dairy protein with prebiotic fiber supplement
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Arizona State University
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