Clinical trials: Effect Neonatal
Atopic Dermatitis, Eczema
Steroid-reducing Effects of Crisaborole
Atopic dermatitis, or eczema, is a chronic skin condition affecting many children. Crisaborole is a non-steroid topical medication which is FDA approved for children aged 2 and older for eczema.
- Trial name
- NCT03832010
- Testing
- Crisaborole, Hydrocortisone Ointment, Triamcinolone ointment
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Breast Milk Expression, Breast Milk Collection
The Effect of Showing Photographs, Videos and Live Images of Their Babies to Mothers During Milking
The study was planned to determine the effect of showing photographs, videos and live images of premature babies who could not be breastfed in the neonatal intensive care unit to their mothers on the amount of breast milk…
- Conditions
- Breast Milk Expression, Breast Milk Collection, Mother-Infant Interaction
- Trial name
- NCT05700162
- Testing
- Photograph, Video, Live Broadcast
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Healthy
Fiber Longer Term Study on Energy Intake
Dietary fibre seems to have a relevant role in body weight management. In an acute study the investigators found that high viscous-high gelling pectin increased feelings of satiety.
- Trial name
- FLiTS (NCT01526759)
- Testing
- LM pectin (10%), gelatin
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Intervention
Effect of Culturally Tailored Health Education on Postnatal Care Use Among Postpartum Women in Ethiopia
This clinical study aims to find out if a redesigned health education program-one that respects local cultural beliefs and is based on well-known behavior change theories-can help improve how well mothers care for their newborns…
- Trial name
- ECTHE (NCT07095296)
- Testing
- Health Education
- Volunteers
- 864 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Pregnancy; Spina Bifida, Fetal, Environmental Exposure
Understanding Effects of Folic Acid on the Methylosome and Transcriptome of Women With Spina Bifida Affected Pregnancies
Folic acid is currently considered to be the standard of care for primary and secondary prevention of spina bifida, but the mechanisms underlying folic acid's benefits are unknown.
- Trial name
- NCT05500690
- Testing
- Folic Acid Tablet
- Where
- Bangladesh
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Chorioamnionitis, Intrauterine Infection
Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term
This prospective randomized controlled study examines whether the type of glove used (sterile vs clean) for cervical examination to assess progression in labor impacts the rates of intrapartum and/or postpartum infection in…
- Conditions
- Chorioamnionitis, Intrauterine Infection, Postpartum Endometritis, Puerperal Infection
- Trial name
- NCT05603624
- Testing
- Cervical examination to assess labor
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Adverse Effect of Oral Contraceptives, Initial Encounter
The Effect of Hormonal Contraception on Female
The aim- To evaluate the impact of combined oral contraceptives on women's psychosexual, metabolic, blood coagulation, hormonal and genetic measures.
- Trial name
- HORMCONTRA (NCT01852786)
- Testing
- Contraceptives, Oral, Combined, Controls
- Where
- Lithuania
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Pain, Procedural Pain
The Effect of Pain Management Education on The Mothers in Newborn
The aim of this study was to determine the effect of non-pharmacological pain management education given to mothers on the use of non-pharmacological methods and anxiety levels of mothers during routine heel blood collection…
- Conditions
- Pain, Procedural Pain, Infant ALL
- Trial name
- NCT05173662
- Testing
- Providing education and brochures on non-pharmacological methods that can be applied during the heel blood collection process
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Hyperuricemia, Gout
Effect of Quercetin Supplements on Healthy Males: a Four-Week Randomized Cross-Over Trial
The purpose of this study was to test the effect of chronic consumption of Quercetin 500 mg tablets on blood uric acid and other biomarkers in adult males.
- Conditions
- Hyperuricemia, Gout, Kidney Calculi, Diabetes
- Trial name
- NCT01881919
- Testing
- Treatment, Control
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Respiratory System Abnormalities
Comparison of Effects of PEEP Levels on Respiratory Mechanics in Patients Undergoing Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is accepted as gold standard in the management of cholelithiasis. Although laparoscopic procedures have many advantages,intra-abdominal CO2 insufflation can cause decreased lung volumes and…
- Trial name
- NCT02439801
- Testing
- PEEP 0, PEEP 5, PEEP 8
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Premature, Thermoregulation
Delaying First Bathing and Skin Barrier Function on Infant
It is still unknown when the first bath should be done in premature newborns. Investigators think that delaying the time of the first bath compared to the time in the clinic will show some positive changes in preterm newborns.
- Trial name
- TEWL (NCT04231799)
- Testing
- Bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Manual Lymphatic Drainage, Swedish Massage
Comparison of Acute Effect of Different Manual Techniques on Muscle Fascia Stiffness
There are studies investigating the effect of different massage methods on muscle fascia stiffness but the results do not support each other.
- Conditions
- Manual Lymphatic Drainage, Swedish Massage, Muscle Fascia Stiffness
- Trial name
- NCT04324775
- Testing
- Exercise + Manual Lymphatic Drainage, Exercise + Swedish massage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Obstetric Pain
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
During labor there is an increased production of inflammatory mediators called cytokines. Higher concentration of certain cytokines has been linked to adverse neonatal and maternal outcomes.
- Trial name
- NCT00361712
- Testing
- Preemptive epidural analgesia, Standard of care
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Heel Lance Procedures
Non-Pharmacological Methods in Heel Lance
This randomized controlled study was designed to compare the effects of Warm Foot Bath, ShotBlocker®, and Buzzy®-applied prior to heel lance-on the vital signs of newborns.
- Trial name
- NCT07348731
- Testing
- Foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Atlas University
Hypertriglyceridemia, Familial Chylomicronemia
Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single- and multiple doses of ARO-APOC3 in healthy adult volunteers and in patients with severe hypertriglyceridemia and…
- Trial name
- NCT03783377
- Testing
- ARO-APOC3, sterile normal saline (0.9% NaCl)
- Where
- 10 sites in Australia, Canada and 1 more
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Arrowhead Pharmaceuticals
Functional Gastrointestinal Disorders (FGIDs), Weight Loss
Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates
Infants born by cesarean section commonly show early weight loss and slower recovery of birth weight, together with characteristic patterns of gut microbiota dysbiosis marked by reduced Bifidobacterium and Bacteroides and…
- Trial name
- NCT07320287
- Testing
- RO water, LiveSpo PREG-MOM, LiveSpo CONSY
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Balance; Distorted, Fascia; Anomaly
Fascia Release Techniques Applied to Plantar Flexor Muscles and Acute Efficacy of Kinesio Taping
The aim of this study; The aim of this study is to examine the effects of kinesio taping technique and percussive massage technique applied to plantar flexor muscles on proprioception, balance and flexibility in healthy…
- Trial name
- NCT06006533
- Testing
- taping, massage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Cancer, Pregnancy
Effects of Oncological Treatment During Pregnancy on Mother and Child
The researchers aim to investigate the outcome (overall survival) of mothers who are diagnosed and/or treated for cancer during pregnancy.
- Trial name
- NCT00330447
- Where
- 33 sites in United States, Argentina and 18 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Healthy
A Comparative Bioavailability/Food Effect Study of Immediate-Release and Extended-Release Tramadol HCl/Acetaminophen Combination Products Following Single-Dose and Multiple-Dose Administration in Healthy Adult Volunteers
The objectives of this two-part study were to compare the single-dose and multiple-dose pharmacokinetics of extended release and immediate-release fixed combination formulations containing tramadol-HCl/acetaminophen and to…
- Trial name
- NCT00973232
- Testing
- DDS-06C (650 mg acetaminophen and 75 mg tramadol HCl), DDS-06C (650 mg acetaminophen and 75 mg tramadol), Zaldiar®
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Labopharm Inc.
Labour Analgesia and Neonate Activity
Labour Analgesia and Movement in Babies
This study aims to measure movements in babies after they are born using an actigraph, a wristwatch-sized device worn on the ankle, which works similarly to the device used by runners to count the number of steps they have taken.
- Trial name
- LAMB (NCT01280084)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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