Clinical trials: Effect of Exercise on Cognitive Function
Healthy
Pre-Workout on Exercise Performance and Cognition
The purpose of this study is to determine the effects of four different pre-workout beverages as compared to placebo on muscular strength and endurance, perceived energy and cognitive performance in healthy adult males.
- Trial name
- NCT02255201
- Testing
- Master Performance Blend Dose 1, Master Performance Blend Dose 2, Performance Energy Blend
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Miami Research Associates
Cognition, Sodium Bicarbonate
Exercise-Induced Lactate and Cognitive Function (ExLBC)
A single bout of exercise can rapidly improve cognitive functions including memory, attention, and executive functions, which help us navigate through everyday life.
- Conditions
- Cognition, Sodium Bicarbonate, Lactate, Exercise
- Trial name
- NCT06817681
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McMaster University
Exercise, Ultra-endurance Running
Effect of Exogenous Ketosis During Ultra-endurance Exercise
The aim of this study is to investigate the effect of oral ketone administration during and immediately after an ultramarathon. Potential changes in cognitive function (reaction time, number of errors), running performance, jump…
- Conditions
- Exercise, Ultra-endurance Running, Ketosis, Skeletal Muscle
- Trial name
- NCT05407753
- Testing
- Ketone ester
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Stroke
Effects of Aerobic Exercise on the Cerebral Arterial System, Cognitive, and Motor Function in Post-stroke Patients.
Background: Stroke is the second leading cause of death and disability worldwide and in Hong Kong, 6.2% of all registered deaths in 2020 were due to cerebrovascular disease.
- Trial name
- NCT05706168
- Testing
- treadmill exercise, Cycle ergometer exercise
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment, Alzheimer Disease
Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs
The purpose of this study is to determine specific changes in muscle secretory profile (myokines, miRNA) in association with neurodegenerative disease progression and metabolic dysfunction.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Parkinson Disease, Healthy Volunteers
- Trial name
- Brain-Muscle (NCT02253732)
- Testing
- 3 months exercise intervention program
- Where
- 2 sites in Slovakia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Mild Cognitive Impairment, Prediabetes
Piedmont Aging, Cognition & Exercise Study-2
The purpose of this research study is to examine the effects of high and low intensity exercise for those with mild memory loss and pre-diabetes.
- Trial name
- PACE-2 (NCT02312843)
- Testing
- Exercise/Aerobic, Exercise/Stretching
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Multiple Sclerosis
Structured Exercise Training in Newly Diagnosed Multiple Sclerosis
the effectiveness of structured exercise training will be investigated for individuals with MS who are newly diagnosed and have no clinical problems.
- Trial name
- NCT05957809
- Testing
- Structured exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Screen Time, Performance Enhancing
The Effect of Aerobic Exercise Training on Collegiate eSport Team Players
E-sports, which is called video games that are played in a competitive and organized way in a virtual environment, individually or in like teams, continues to increase its popularity by reaching individuals of all ages with the…
- Conditions
- Screen Time, Performance Enhancing, Injury Prevention, Executive Function
- Trial name
- NCT05317104
- Testing
- Aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Acute Kidney Injury, Exertional Heat Illness
Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat
The goal of this clinical trial is to learn if one week of creatine monohydrate supplementation alters inflammation, markers of acute kidney injury (AKI) risk, and cognitive performance in active, young, healthy volunteers.
- Trial name
- NCT07472426
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Glucose Intolerance, Energy Expenditure
Effects of Acute Sleep Deprivation on Health
This study will investigate whether various types of regular exercise can provide protective effects against metabolic abnormalities induced by sleep restriction.
- Conditions
- Glucose Intolerance, Energy Expenditure, Vascular Stiffness, Cognition
- Trial name
- NCT07403864
- Testing
- Normal sleep, Partial sleep deprivation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Aerobic Exercise, Anaerobic Exercise
The Effect of Physical Activity on the Brain
Physical activity is thought to increase overall body functions and to decrease cardiovascular and stroke risk factors. Now the question arose, wether enhanced exercise could also exert positive influence on cognition in the…
- Conditions
- Aerobic Exercise, Anaerobic Exercise, Unchanged Condition
- Trial name
- NCT01475396
- Testing
- exercise
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Tobacco Use Disorder, Nicotine Dependence, Cigarettes
Effects of Nicotine Dependence on Multidimensional Health Outcomes
Nicotine, a major toxic component of cigarette smoke, together with carbon monoxide (CO), constitutes a significant environmental exposure with systemic effects.
- Trial name
- NCT07474623
- Testing
- Comprehensive Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Young Healthy Adults
Effect of High-Intensity Interval Training Exercise on Cognitive Function of Young Adults
To explore the sustainability of the acute effect of High Intensity Interval Training (HIIT) on executive function in young adults.
- Trial name
- NCT06621550
- Testing
- High Intensity Interval Training
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cognitive Change, Well-Being, Psychological
Acute Effects of Physical Activity on Cognition and Well-being in University Students
Previous studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions.
- Trial name
- ActClass4Brain (NCT06168526)
- Testing
- Acute physical activity
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Cognitive Function, Balance Impairment
Effects of Action Observation Therapy in Geriatric Individuals
This randomized controlled trial aimed to investigate the effects of Action Observation Therapy (AOT) on cognitive function, balance, fatigue, and functional capacity in geriatric individuals.
- Conditions
- Cognitive Function, Balance Impairment, Fatigue, Aging
- Trial name
- NCT07418970
- Testing
- Action, Action Observation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Effect of Superstarch on Soccer Performance
Superstarch and Physical/Cognitive Performance Following a Simulated Soccer Game
To assess the efficacy of a hydrothermally modified starch supplement (Superstarch made byGeneration UCAN) vs isoenergetic placebo (glucose) on exercise performance, execution of specific soccer skills, and on cognitive function…
- Trial name
- NCT02667340
- Testing
- Superstarch
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Aging, Cognitive Performance
Visual Stimulus-Based Cognitive-Motor Agility Exercise in Older Adults
This randomized controlled trial examined the effects of adding a brief visual stimulus-based cognitive-motor agility exercise component to a multicomponent exercise program in community-dwelling older adults.
- Conditions
- Aging, Cognitive Performance, Psychomotor Performance, Exercise
- Trial name
- NCT07714148
- Testing
- Multicomponent Exercise Program, Visual Stimulus-Based Cognitive-Motor Agility Exercise, Time-Matched Low-Intensity Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Frailty, Aging
Multicomponent Exercise and Virtual Reality for Older Adults
Population aging is associated with an increased risk of frailty, falls, and loss of autonomy. This pilot study aims to evaluate the effects of a program that combines multicomponent exercise and non-immersive virtual reality…
- Conditions
- Frailty, Aging, Functional Impairment
- Trial name
- MOVE ON (NCT07529743)
- Testing
- Multicomponent Exercise plus Non-Immersive Virtual Reality, Non-Immersive Virtual Reality
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Sleep Quality, Cognitive Function
Effects of Walking Exercise on Sleep Quality in Older Adults
This study aims to explore whether increasing physical activity can improve sleep quality in older adults, particularly those with poor sleep, and whether such improvements positively influence cognitive functions such as memory…
- Trial name
- NCT07027176
- Testing
- walking exercise
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yea-Ru Yang