Clinical trials: Effect of Laryngoscopy and Tracheal Intubation
Intubation Complication, Cardiovascular Morbidity
The Effects of Lidocaine and Magnesium Sulphate on the Attenuation of the Hemodynamic Response to Tracheal Intubation
Justification and Objectives: The hemodynamic response to stimuli of the airways is a common phenomenon and its control is important to decrease systemic repercussions.
- Trial name
- NCT02359370
- Testing
- Lidocaine, Magnesium Sulphate
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Effect of Laryngoscopy and Tracheal Intubation
Pregabalin Stabilize Cardiovascular Response to Intubation
The purpose of the study is to evaluate whether Pregabalin is safe and effective in stabilizing cardiovascular response to laryngoscopy and tracheal intubation of patients under general anesthesia.
- Trial name
- NCT03456947
- Testing
- Pregabalin
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
General Anesthesia
Comparison of the Effects of Dexmedetomidine and Lidocaine on Blood Pressure and Heart Rate Response
Endotracheal intubation is considered a definitive therapy and the gold standard for airway management. However, this procedure carries several risks, including sudden increases in blood pressure and heart rate.
- Trial name
- NCT06573957
- Testing
- Dexmedetomidine, Lidocain
- Where
- Indonesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Intubation, Endotracheal, Anesthesia, General
A Comparison of Two GlideScope Intubation Techniques
The aim of this study is to compare the hemodynamic response to tracheal intubations using the standard technique versus the alternative GS intubation technique.
- Trial name
- NCT01865643
- Testing
- GlideScope
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Intraocular Pressure, Intubation Complication
Effects of Direct Laryngoscopic and Fiberoptic Intubation on Intraocular Pressure
In this study, the investigators aimed to compare the effects of direct laryngoscopic and fiberoptic endotracheal intubation on intraocular pressure.
- Trial name
- NCT03003585
- Testing
- Direct laryngoscope, Fiberoptic bronchoscope
- Volunteers
- 54 people
- Sponsor
- Inonu University
Intravenous Anesthetic Agent Overdose
Interest of a Tetanus Test at a Fixed Remifentanil Concentration Before Laryngoscopy and Skin Incision
Individually-tailored administration of the opioid analgesic component during general anaesthesia is still a challenge for the anesthesiologist.
- Trial name
- NCT02884310
- Testing
- Remifentanil adapted to SPI, Remifentanil fixed
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Anesthesia, Anesthesia Intubation
Opioid-based Versus Opioid-free Endotracheal Intubation
The aim of this study will be to investigate the effect of opioid-free induction versus opioid-based induction on hemodynamic response and nociception level index during elective operations
- Conditions
- Anesthesia, Anesthesia Intubation, Opioid Use, Analgesic Non-narcotic
- Trial name
- NCT06464393
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital
Dexmedetomidine, Intubation Complication
Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.
Dexmedetomidine bolus dose may provide similar or less hemodynamic changes (less bradycardia and less hypertension) than infusion dose during induction of anaesthesia and tracheal intubation.
- Trial name
- NCT06327399
- Testing
- Dexmedetomidine infusion, Dexmedetomidine bolus, Atropine Sulfate
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Cardiac Arrest
Intubation During Adult Intubation
The objective of this study is to compared effectiveness of intubation using ETView VivaSight SL and standard tracheal tube during resuscitation performed by a EMS-paramedics.
- Trial name
- SLETI (NCT02305524)
- Testing
- ETView VivaSight SL, Macintosh laryngoscope
- Where
- Poland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Intracranial Hypertension, Endotracheal Intubation
Lidocaine, Dexmedetomidine, Esmolol and Magnesium Effect on Optic Nerve Sheath Diameter After Laryngoscopy
This clinical trial aims to compare the effects of lidocaine, dexmedetomidine, esmolol, and magnesium on optic nerve sheath diameter and hemodynamic response to laryngoscopy.
- Conditions
- Intracranial Hypertension, Endotracheal Intubation, Optic Nerve Sheath Diameter, General Anesthesia
- Trial name
- NCT06254534
- Testing
- optic nerve ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Haseki Training and Research Hospital
One Lung Ventilation in Thoracic Surgery
Comparison of Double-lumen Tube Intubation Between Fiberoptic Bronchoscopy and Video Laryngoscope
The goal of this clinical trial is to compare the first-attempt success rate in double-lumen tube intubation. The main question it aims to answer: Is there any difference in the first-attempt success rate of intubation between…
- Trial name
- NCT07241208
- Testing
- Fibertoptic Bronchoscopy
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
To Measure Systolic Blood Pressure Postintubation
Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response
Many studies discussed attenuating stress response by various measures but to the interest of our study , No one compared topical spray of both lidocaine and dexmedetomidine in attenuating the haemodynamic stress responses of…
- Trial name
- NCT06374017
- Testing
- Normal saline, Lidocaine, dexmetomidine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kasr El Aini Hospital
Effect of Laryngoscopy and Tracheal Intubation
Oral Amantadine Versus Gabapentin to Attenuate the Response to Laryngoscopy and Tracheal Intubation
To evaluate the effect of oral amantadine versus gabapentin premedication on the hemodynamic response to laryngoscopy and tracheal intubation and their effect on β-endorphins.
- Trial name
- 15/5/2017 (NCT03172234)
- Testing
- oral amantadine sulfate, oral gabapentin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ghada Mohammed AboelFadl
Lidocaine
Lidocaine in the Prevention of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation
Direct laryngoscopy and endotracheal intubation procedure stimulate the sympathetic nervous system, causing catecholamine release into the circulation and consequently hemodynamic changes.There are many studies showing that…
- Trial name
- NCT06107543
- Testing
- Nebulized Lidocaine, Iv Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Neurosurgical Patients
Effect of Lidocaine Sprayed on Hemodynamics During Endotracheal Intubation
A previous study demonstrated topical lidocaine spray on the larynx and the trachea is effective in reducing hemodynamic response to laryngoscopy and endotracheal intubation.
- Trial name
- NCT01737437
- Testing
- group C, group L, group V
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital