Clinical trials: Effect of Sleep Deprivation
Sleep Deprivation, Circadian Rhythm Disorders
PBM Effects on Health and Well-being in Humans
The goal of this clinical study is to assess the effects of different photobiomodulation (PBM) conditions in men and women between 25 and 65 years old with daytime sleepiness/drowsiness and /or mild mood complaints but be…
- Trial name
- NCT05619133
- Testing
- PBM
- Where
- Netherlands
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seaborough Life Science B.V.
Delayed-onset Muscle Soreness, Sleep
Sleep and Delayed-onset Muscle Soreness
There is a need for further experimental research in order to gain a more in-depth understanding of this vicious cycle of pain and sleep disorders.
- Conditions
- Delayed-onset Muscle Soreness, Sleep, Pain
- Trial name
- NCT06699186
- Testing
- Sleep, Non-sleep
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Sleep
Stable Sleep Pattern Before Sleep Loss
Sleep is now recognized as important for disease prevention. Too little or too much sleep contributes to cardiovascular disease. Leading health organizations recommend adults sleep 7-9 hours per night for optimal health.
- Trial name
- NCT06201390
- Testing
- Sleep consistency
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Aging, Sleep Deprivation
Effects of Chronic Sleep Restriction in Young and Older People
The purpose of this study is to examine the consequences of chronic sleep restriction on nighttime sleep, daytime alertness, performance and memory functions, and metabolic and cardiovascular function, and to determine if the…
- Conditions
- Aging, Sleep Deprivation, Metabolic Syndrome
- Trial name
- NCT00506428
- Testing
- chronic sleep restriction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Healthy
Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers
The aim of this study is to assess the utility of sleep deprivation as a potential model for prediction of clinical efficacy using a combination of cognitive physiological endpoints.
- Trial name
- NCT01461174
- Testing
- Modafinil, Donepezil, Memantine
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Qualissima
Sleep Disorder, Sleep, Inadequate
Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Postoperative sleep disorders have serious problems with cognition, pain perception, sustained circadian rhythm, psychomotor function, metabolic function, catabolic responses, and continuity.
- Conditions
- Sleep Disorder, Sleep, Inadequate, Total ıntravenous Anesthesia, Inhalation Anesthesia
- Trial name
- NCT06269328
- Testing
- Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance, Inhalation anesthesia with sevoflurane for anesthetic maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Uludag University
Sleep Deprivation
The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Processing in Young and Old
The main purpose of this study is to investigate the effects of partial sleep deprivation (PSD) on resting state brain connectivity, emotional contagion, empathy, and emotional regulation.
- Trial name
- NCT02000076
- Testing
- Partial sleep deprivation allowing 3 h sleep at night, Full sleep
- Where
- Sweden
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mats Lekander
Lifestyle Factors, Overweight and Obesity
Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity.
- Conditions
- Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit
- Trial name
- NCT06180837
- Testing
- Sleep Extension Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sleep Deprivation
Effect of Sleep Deprivation on Sensory Integration of Balance, Fall Risk and Postural Stability
Sleepiness caused by sleep deprivation may increase the risk of injuries and damages during physical activity. Individual data so far indicates worsening of postural stability and control with females exhibiting better static…
- Trial name
- NCT05170191
- Testing
- Sleep Deprivation
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Healthy Volunteers
Sleep Deprivation : Effects on Driving Performance and Central Fatigue
The effects of sleep deprivation (SD) on performance, while contradictory at first glance, are in reality rather clear when exercise duration is considered, i.e. intense/supramaximal versus prolonged exercises.
- Trial name
- PrivSom (NCT01606020)
- Testing
- sleep deprivation, No intervention
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Major Depressive Disorder, Bipolar Disorder
The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients
This study evaluates the efficacy of sleep deprivation treatment in accelerating antidepressant responses when administered during the first week of medications and augmenting a sustained response with chronobiological…
- Trial name
- NCT00581009
- Testing
- chronobiological augmentation, sertraline, lithium, one night of sleep deprivation and two FDG PET scans
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Control, 1 Night Recovery Sleep
Neurobehavioral Effects of Partial Sleep Deprivation
This project continues an innovative line of research on how to optimally use sleep as an intervention to promote cognitive recovery from, and resistance to, the neurobehavioral risks posed by chronic partial sleep deprivation.
- Conditions
- Control, 1 Night Recovery Sleep, 3 Nights Recovery Sleep, 5 Nights Recovery Sleep
- Trial name
- NCT02128737
- Testing
- Sleep
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Deprivation, Mental Competency
Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep
The purpose of this study is to determine if the enhancement of electroencephalographic (EEG) slow-wave activity using transcranial electrical stimulation (TES) at Slow Oscillation (SO) frequency, during a restricted period of…
- Trial name
- NCT02945501
- Testing
- NeuroConn DC Stimulator PLUS
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Healthy
The Effect of Sleep Deprivation on Passive and Active Functions and Distance Modulation of the Vestibulo-Ocular Reflex
The goal of this cross-over clinical trial is to evaluate the effect of 24 hours sleep deprivation on the Vestibulo-Ocular Reflex (VOR) in healthy participants. The main questions it aims to answer are: 1.
- Trial name
- NCT05850767
- Testing
- Sleep deprivation
- Where
- Israel
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Yoav Gimon
Sleep Deprivation, Menstrual Cycle
The Effects of Night Shift Work on Health Across the Menstrual Cycle
The study aims to investigate the effects of sleep deprivation on women's health across different phases of the menstrual cycle.
- Conditions
- Sleep Deprivation, Menstrual Cycle, Brain Health, Metabolism
- Trial name
- MENSLEEP (NCT06683248)
- Testing
- Investigate sleep deprivation
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sleep Quality
Examining the Differential Effects of Traditional Float-REST on Sleep and Recovery
The objective of this research study is to assess how the implementation of Float-REST affects sleep quality, sleep structure, nocturnal physiology, subjective wellness, recovery from stressors, and resultant effects on…
- Trial name
- NCT05154032
- Testing
- Traditional Float-REST Therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Sleep Hygiene
The Effect of Sleep Hygiene Training Implemented
Good and quality sleep, which has an important place in the lives of all living things; important for the health and well-being of children. Proper sleep habits are needed for quality and adequate sleep.
- Trial name
- NCT05957874
- Testing
- Combined package program
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Sleep Deprivation
Effects of Sleep Loss on Endothelial Function and Cytokine Levels in Internal Medicine Residents
Work requirements for medical trainees result in substantial sleep loss. Sleep loss has been associated with increased levels of certain inflammatory hormones that could have negative impact on blood vessel function.
- Trial name
- NCT00272233
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yale University
Sleep Deprivation, Sleep Wake Disorders
Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans
The project is aimed at identifying how the adrenergic antagonist 'carvedilol' modulates the effects of sleep deprivation in healthy volunteers. The study is a double-blind, randomized, placebo-controlled, cross-over study.
- Conditions
- Sleep Deprivation, Sleep Wake Disorders, Sleep
- Trial name
- NCT03576664
- Testing
- Carvedilol 25mg
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen
Sleep Deprivation
Effect of Nap on Daytime Functioning in Primary School Students
Previous studies showed that insufficient sleep has a negative impact on children's physical and psychological health. Napping was found to decrease sleepiness and improve daytime functioning in adults and adolescents.
- Trial name
- NCT04270539
- Testing
- Nap
- Where
- Hong Kong
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong