Clinical trials: Effectiveness
Tinea Cruris
Comparative Efficacy of Topical Oxiconazole Cream (1%) Versus Topical Clotrimazole Cream (1%) in the Treatment of Tinea CrurisAbstract
This study is conducted to compare the efficacy of topical oxiconazole 1% cream versus topical clotrimazole 1% cream in patients with tinea cruris.
- Trial name
- NCT07441005
- Testing
- Topical Oxiconazole cream, Topical Clotrimazole cream
- Where
- Pakistan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Sexually Transmitted Diseases, Unsafe Sex
Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders
This study is a randomized controlled trial (RCT) that will rigorously evaluate the implementation, effectiveness and cost-effectiveness of a couple-based integrated human immunodeficiency virus (HIV) and drug abuse prevention…
- Conditions
- Sexually Transmitted Diseases, Unsafe Sex, Substance-Related Disorders
- Trial name
- PACT (NCT01690494)
- Testing
- PACT, TAU
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Columbia University
Vulvar Atrophy
Evaluation of the Safety and Efficacy of Hyaluronic Acid Injection in Labia Majora Augmentation
The goal of this interventional clinical investigation using Genefill Contour® CE marked device outside of its indication is to compare with other hyaluronic acid device already marketed for labia majora augmentation in women…
- Trial name
- NCT06333782
- Testing
- Experimental- Genefill Contour®, Marketed comparator - Desirial®Plus
- Where
- 3 sites in France, Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Bioscience Cosmetics SL
Acne
Safety and Efficacy of Skin Cleanser Contained Roselle Extract in Acne
Skin cleanser for daily used is essential and one of the most common questions asked by acne patients. There are studies reported beneficial effects of cleansers in acne treatment.
- Trial name
- NCT00701480
- Testing
- skin cleanser contained Hibiscus sabdariffa extract, marketed skin cleanser
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Thammasat University
BCG, COVID-19
Prevention, Efficacy and Safety of BCG Vaccine in COVID-19 Among Healthcare Workers
In Mexico the total number of confirmed cases of COVID-19 is 232, 000 and 28,510 deaths. Health workers are at high risk of COVID-19 infection. Their absence from work dramatically limits the ability to contain the disease.
- Conditions
- BCG, COVID-19, SARS-CoV2, Corona Virus Infection
- Trial name
- NCT04461379
- Testing
- BCG vaccine
- Where
- Mexico
- Volunteers
- 908 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Telerehabilitation
Training Intervention and Program of Support (TIPS): Fostering Family-centred Telehealth in Pediatric Rehabilitation
Timely access to family-centred services for children with disability and their families is important to support their development and well-being. Currently, many children face long wait times and barriers to services.
- Trial name
- TIPS (NCT05312827)
- Testing
- Training Intervention and Program of Support (TIPS) for fostering the adoption of family-centred telehealth interventions in pediatric rehabilitation
- Where
- 3 sites in Canada
- Volunteers
- 2,360 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Tumor, Chemotherapy-induced Nausea and Vomiting
the Efficacy and Safety of 5-HT3 Receptor Antagonist, Dexamethasone or Megestrol Acetate Dispersible Tablets in the Control of Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy
To compare the efficacy and safety of megestrol acetate dispersible tablets combined with 5-HT3 receptor antagonist and dexamethasone triple antiemetic regimen and 5-HT3 receptor antagonist and dexamethasone combined antiemetic…
- Trial name
- NCT04430361
- Testing
- Megestrol, 5-HT3 receptor antagonist, dexamethasone
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henan Cancer Hospital
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Schizophrenia
Effectiveness of Family Group Interventions for People With Schizophrenia
The mutual support group intervention would significantly improve the families' burden of care, functioning and social support, reduce the patients' severity of symptoms and re-hospitalizations, and reduce the demands for…
- Trial name
- MSG (NCT00940394)
- Testing
- mutual support group, psychoeducation group, Standard care
- Where
- 2 sites in Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Shift Work Type Circadian Rhythm Sleep Disorder
The Effectiveness of Using Low-level Light Therapy to Treat Sleep and Psychological Symptoms Among Shift-work Nurses
The purpose of this study is to explore the treatment of Low Level Light Therapy(LLLT) mitigate possible insomnia and psychological symptoms, when nurses have taken shifts.The investigators hope that the goal of this…
- Trial name
- t-PBM (NCT05146596)
- Testing
- use low level light therapy,The Dr.Tai's energy cap
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Melanoma
Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT)
Melanoma is an immune-modulated malignancy and immune checkpoint modulators which inhibit PD-1 function (pembrolizumab, nivolumab) have demonstrated clinical efficacy as treatment for patients with stage IV melanoma.
- Trial name
- NCT03241927
- Testing
- Pembrolizumab
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Nina Bhardwaj
Typhoid Vaccination, Typhoid
ZyVac-TCV Bangladesh Study
This is a prospective closed cohort, open-label, phase III effectiveness study using a test-negative design of a typhoid conjugate vaccine, ZyVac® TCV (purified Vi capsular polysaccharide of Salmonella Typhi conjugated to tetanus…
- Conditions
- Typhoid Vaccination, Typhoid, Typhoid Fever
- Trial name
- NCT06757283
- Testing
- Purified Vi capsular polysaccharide of Salmonella typhi conjugated to tetanus toxoid as carrier protein (Typhoid Vi Conjugate Vaccine I.P.). Trade name: ZyVac® TCV
- Where
- Bangladesh
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Gastroenteritis
Efficacy and Safety of Two Doses of HIL-214 in Children
This is a randomized, placebo-controlled study that is being done to evaluate the safety and effectiveness of two doses of the HIL-214 vaccine compared to a placebo.
- Trial name
- NCT05281094
- Testing
- HIL-214
- Where
- 17 sites in United States, Colombia and 5 more
- Volunteers
- 3,084 people, healthy volunteers welcome
- Sponsor
- HilleVax
Alcohol Drinking
Effectiveness of a Peer-led Program to Prevent Alcohol Consumption.
The goal of this Randomized clinical trial is to evaluate the effectiveness of a peer-led intervention to prevent alcohol consumption in university students.
- Trial name
- NCT05639374
- Testing
- BASICS_HealthyClassroom
- Where
- Spain
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Breast Feeding
Peer Assisted Breastfeeding Education Program
It was aimed to evaluate the effect of the Peer Supported Breastfeeding Education Program given during the antenatal period on the breastfeeding knowledge and attitude levels, breastfeeding self-efficacy and breastfeeding levels…
- Trial name
- PABEP (NCT06493474)
- Testing
- Education, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cutis Laxa
Effectiveness and Safety of the Ulthera® System for Skin Laxity in the Lower Face, Submentum and Neck
The purpose of this study is to demonstrate superiority of treatment with the Ulthera System compared to untreated control for the improvement of skin laxity of the lower face, submental area and neck and to demonstrate the…
- Trial name
- NCT07614997
- Testing
- Ulthera System
- Where
- 7 sites in China
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Ductal Carcinoma in Situ
Acceptability of Active Monitoring (AM) as a Treatment Option for Ductal Carcinoma in Situ (DCIS)
The purpose of this research study is to evaluate a decision support tool for patients diagnosed with ductal carcinoma in situ (DCIS).
- Trial name
- NCT03775213
- Testing
- Decision Support Tool with Active Monitoring, Decision Support Tool without Active Monitoring
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Duke University
Anemia
Efficacy and Safety of Heme-Iron Polypeptide on Improvement of Anemia
The investigators performed a 4-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Heme-Iron Polypeptide on Improvement of Anemia.
- Trial name
- NCT01733979
- Testing
- Heme-Iron Polypeptide, Heme-Iron, Organic Iron
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Total Knee Arthroplasty
The Analgesic Effect of Nitroglycerin Patch for Postoperative Pain After Total Knee Replacement
Patients who undergo general anestheesia for total knee arthroplasty pften have sever postoperative pain which hinders their rehabilitation.
- Trial name
- NCT00375362
- Testing
- Nitroderm patch
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
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