Clinical trials: Effectiveness
Corneal Epithelial Wound Healing
Efficacy of Topical Insuline in Corneal Epithelial Healing Post PRK
A prospective randomized double-blind controlled trial will be conducted. The informed consent of each patient will be obtained prior to the procedure.
- Trial name
- NCT06956846
- Testing
- insulin eye drops, Artificial tears eye-drops
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hotel Dieu de France Hospital
Healthy Population
A Study to Determine Safety, Pharmakokinetics and Efficacy of the Different Doses of VL-SE-01 in Healthy Participants.
The present study is a randomized, placebo-controlled, parallel study. 250 participants will be screened, and considering a screening failure rate of 20%, approximately 200 participants will be randomized in a ratio of 1:1:1:1:1…
- Trial name
- NCT06473246
- Testing
- CBD Isolate (25 mg/0.5 ml), CBD Isolate (40 mg/0.5 ml), CBD Isolate (50 mg/0.5 ml)
- Where
- 6 sites in India
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Pain Management, Pain Assessment
Effectiveness and Implementation of a Clinical Pain Management Dashboard for the NICU
This study protocol describes a type 1 hybrid effectiveness-implementation study evaluating a clinical decision support dashboard for neonatal pain management in a tertiary NICU.
- Conditions
- Pain Management, Pain Assessment, Neonatal Intensive Care, Implementation Research
- Trial name
- NCT07629661
- Testing
- Implementation of clinical pain management dashboard
- Where
- Netherlands
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Functional Fitness, Cognitive Abilities
High-Intensity Exercise in Older Adults
The goal of this interventional study was to test the high-intensity interval training called Aphasia Physical Exercise (APEX) in healthy older adults. The main questions it aimed to answer were: 1.
- Trial name
- NCT06199661
- Testing
- APEX
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Sensitivity
Efficacy of Desensitizers in Reducing Post-operative Sensitivity Following Composite Restorations
Composite is one of the common aesthetic restorations used in the dentistry. With the advancements in the biomaterials the application of the composites has broadened.
- Trial name
- NCT05024669
- Testing
- Gluma desensitiser, Sheildforce Plus desensitiser, Telio CS desensitiser
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Jazan
HIV Infections, AIDS
Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission
The purposes of this study are to determine whether Carraguard® Gel can prevent the transmission of HIV when used during vaginal intercourse, and to confirm that the gel is safe for vaginal use.
- Conditions
- HIV Infections, AIDS, Sexually Transmitted Diseases, HIV Seroconversion
- Trial name
- NCT00213083
- Testing
- Carraguard (PC-515)
- Where
- 3 sites in South Africa
- Volunteers
- 6,203 people, healthy volunteers welcome
- Sponsor
- Population Council
Childhood Obesity, Child Obesity
Corestability Training in Overweight Children
A total of 52 overweight children aged between eight and sixteen years will be recruited by criterion based purposive sampling to participate in the two groups pretest post test randomized clinical study.
- Conditions
- Childhood Obesity, Child Obesity, Children, Only
- Trial name
- NCT04315220
- Testing
- Corestability training, No Intervention
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Disease Transmission, Vertical, Vertical Human Immunodeficiency Virus Transmission
Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission
Giving anti-HIV medications to babies born of HIV positive mothers right after birth can lower the babies' risk of contracting HIV.
- Conditions
- Disease Transmission, Vertical, Vertical Human Immunodeficiency Virus Transmission, HIV Infections
- Trial name
- NCT00099359
- Testing
- Zidovudine, Nevirapine (NVP), Epivir (3TC)
- Where
- 17 sites in United States, Argentina and 3 more
- Volunteers
- 1,735 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Schizophrenia
Study on Examination of Therapeutic Efficacy and Potential Mechanisms of Yoga Treatment in Schizophrenia
The aim of this study is to examine whether yoga is efficacious as an add-on treatment for negative symptoms of schizophrenia in a randomized multi-centric trial and also to examine functional brain changes associated with…
- Trial name
- SATYAM (NCT03379480)
- Testing
- Yoga arm
- Where
- India
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Small Intestinal Bacterial Overgrowth, Gastrointestinal Disease
Efficacy of AEMCOLO (Rifamycin SV MMX) in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO)
Open label interventional randomized pilot study utilizing two dosing regimens of AEMCOLO. The goal of this study is to evaluate effectiveness of a novel antibiotic, AEMCOLO (Rifamycin SV MMX) in the treatment of Small intestinal…
- Conditions
- Small Intestinal Bacterial Overgrowth, Gastrointestinal Disease, Gastrointestinal Infection
- Trial name
- NCT04501380
- Testing
- AEMCOLO (Rifamycin SV MMX)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bradley Connor
Gluteus Medius Activation
The Effectiveness of Kinesio® Tex Tape on Gluteus Medius Activation in Dancers
The purpose of this research is to determine if a specific type of elasticated athletic tape (Kinesio Tex Tape) increases muscle activation among professional level dancers.
- Trial name
- NCT02741479
- Testing
- Airplane Test
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Contraception
The Safety and Effectiveness of the Essure (Model ESS505) Device to Prevent Pregnancy in Women
To evaluate the safety and long-term (approximately one year) effectiveness of the Essure System for Permanent Birth Control ESS505 device in preventing pregnancy.
- Trial name
- NCT01861886
- Testing
- ESS505 (BAY1454033)
- Where
- 5 sites in Netherlands, Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Bayer
Gingivitis
To Compare the Effectiveness of Three Self-care Oral Hygiene Regimens
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04804670
- Testing
- Power device A, Power device B, Routine Oral Hygiene
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Quality of Life, Breast Cancer
Program of Physical Activity, Nutrition and Supportive to Improve the Quality of Life of Breast Cancer Survivors
Despite it being one of the leading causes of cancer death among women, survival following a breast cancer diagnosis has greatly increased in high-income countries.
- Trial name
- ADA (NCT05658341)
- Testing
- ADA, Usual Care
- Where
- 8 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Siel Bleu
Gingivitis, Plaque
A Twelve Week Study of Experimental Mouth Rinses
The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a hydroalcohol control mouth rinse and a positive control mouth rinse for the reduction of gingivitis and…
- Trial name
- NCT05120141
- Testing
- Colgate Cavity Protection Toothpaste, American Dental Association (ADA) Ref Toothbrush, Prototype 1 Mouth Rinse
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Contraception
Safety and Efficacy of a Contraceptive Vaginal Ring Delivering Nestorone® and Ethinyl Estradiol
The purpose of this 1-year study is to evaluate the efficacy and safety of a new contraceptive vaginal ring (CVR) delivering low doses of Nestorone (NES), a new, nonandrogenic progestin, and ethinyl estradiol (EE), an estrogen…
- Trial name
- NCT00263341
- Testing
- NES/EE CVR
- Where
- 12 sites in United States, Australia and 6 more
- Volunteers
- 1,135 people, healthy volunteers welcome
- Sponsor
- Population Council
Caregivers, Burnout, Psychological
Efficacy of a Multicomponent and Interdisciplinary Intervention on the Care Ability and Burden of Family Caregivers of People With Chronic Cardiocerebrovascular Diseases
The purpose of this intervention is to improve the caregiving ability of family caregivers of people with cardiovascular diseases and therefore reduce burden caregiver through face-to-face, virtual interdisciplinary educational…
- Trial name
- Emiicare (NCT04645290)
- Testing
- Intervention group: Educational Intervention "KARER"
- Where
- 3 sites in Colombia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Claudia Aristizábal
Functional Constipation
The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation
This study aims to evaluate the efficacy and palatability of a developed polyethylene glycol-based formula compared with the standard polyethylene glycol (PEG) in the treatment of children with functional constipation for 8…
- Trial name
- NCT06357897
- Testing
- Local PEG4000, Commercial PEG4000
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Dry Skin
Evaluation of Human Efficacy for Skin Moisturization and Wrinkle Improvement
All subjects used the placebo sample on the left side of their face and the investigational sample on the right side of their face, respectively.
- Trial name
- NCT05872113
- Testing
- Hs-hWE cream
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ji Hye Yoon
Plaque Induced Gingivitis
Comparative Effect of Chewing Sticks and Toothbrushing on Plaque Removal and Gingival Health
The purpose of the proposed study is to compare the effect of chewing sticks (Miswak) and the toothbrushes on plaque removal and gingival health.
- Trial name
- NCT01336179
- Testing
- Salvadora persica, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Taibah University
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