Clinical trials: Effects, Longterm
Caries,Dental
Long-term Effects of a Lay Health Advisor Intervention on Immigrant Children's Caries
The aim of this study was to evaluate the long-term effectiveness of a lay health advisor (LHA) intervention on immigrant children's caries and preventive behaviors.This randomized controlled trial included mother-child pairs in…
- Trial name
- NCT04562675
- Testing
- LHA intervention, brochure-only
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain, Musculoskeletal Manipulations
Effects of a Protocol of Hip Flexor Stretching on Chronic Mechanical, Non-specific LBP.
The goal of this clinical trial is to compare the effectiveness of a stretching, exercise and education protocol versus usual care in improving pain, function and disability in patients with non-specific mechanical chronic low…
- Conditions
- Pain, Musculoskeletal Manipulations, Low Back Pain, Mechanical
- Trial name
- HipFlexinCLBP (NCT06975345)
- Testing
- Multicomponent intervention. Hip flexors stretching, Strengthening exercises and education and medical treatment (Medication and medical counselling), Medical treatment.
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
β-Thalassemia
Extension Study to Evaluate the Safety and Efficacy of Luspatercept in Participants With β-Thalassemia Previously Enrolled in A536-04 (A536-06/MK-6143-004)
Study A536-06 (MK-6143-004) is an open-label extension study for participants previously enrolled in study A536-04 (NCT01749540), to evaluate the long-term safety and tolerability of luspatercept in adult participants with…
- Trial name
- NCT02268409
- Testing
- luspatercept
- Where
- 7 sites in Greece, Italy
- Volunteers
- 51 people
- Sponsor
- Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
Bone Marrow Suppression, Brain and Central Nervous System Tumors
Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, etoposide phosphate, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Bone Marrow Suppression, Brain and Central Nervous System Tumors, Drug/Agent Toxicity by Tissue/Organ, Long-term Effects Secondary to Cancer Therapy in Children
- Trial name
- NCT00238173
- Testing
- filgrastim, acetylcysteine, carboplatin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- OHSU Knight Cancer Institute
Pain, Sleep
Effects of Tactile Touch on Chronic Pain in Parkinson´s Disease
The Parkitouch study compared the effects on pain, sleep quality and HealthRelated Quality of Life (HRQoL) among 44 participants with Parkinson´s Disease for at least two years and chronic pain.The two groups were randomized to…
- Trial name
- NCT01734876
- Testing
- Tactile Touch, Rest To Music
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Region Jönköping County
Submassive Pulmonary Embolism
Long Term Effects of Treating Submassive Pulmonary Embolism With Ultra-sound Accelerated Thrombolysis
Patients with Submassive Pulmonary Embolism treated with ultra-sound therapy will have an improved right ventricular function 72 hours post treatment.
- Trial name
- SPEAR (NCT01899339)
- Testing
- submassive PA treatment with Ekosonic endo device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Corewell Health West
Rhinitis, Allergic, Seasonal
Long-Term Effects of Sublingual Grass Therapy
The purpose of this research study is to investigate whether sublingual immunotherapy (SLIT, grass pollen tablets under the tongue) has long term effects in severe hay fever.
- Trial name
- NCT01335139
- Testing
- Sublingual immunotherapy (SLIT), Subcutaneous immunotherapy (SCIT)
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Growth Disorders, Low Weight
Long Term Effects of Nutritional Supplementation on Final Height
The proposed study is an extension study to two ongoing double blind, randomized, placebo-controlled studies evaluating the effect of gender-specific nutritional supplementation on growth of short and lean adolescent boys and…
- Conditions
- Growth Disorders, Low Weight, Short Stature
- Trial name
- NCT03323177
- Testing
- Gender specific nutritional standardized formula, Follow-up only
- Where
- Israel
- Sponsor
- Rabin Medical Center
Attention Deficit Hyperactivity Disorder
Long-Term Effects of CBT on Quality of Life in Adults With ADHD
Background and objective: Although the short-term effects of cognitive behavioural therapy (CBT) in adult patients with ADHD are established, not a lot is known about longer-term effects.
- Trial name
- CBT-QoL (NCT05290311)
- Testing
- cognitive behavioural therapy
- Where
- Netherlands
- Volunteers
- 155 people
- Sponsor
- Amsterdam UMC, location VUmc
Parenting, Parent-Child Relations
Middle School Success Over Stress
It is clear that the COVID-19 pandemic has impacted families adversely in multiple ways, including economic stressors, mental health-related functioning, social/familial functioning, as well as responses to mandated safety…
- Conditions
- Parenting, Parent-Child Relations, Depression, Self-regulation
- Trial name
- MSSOS (NCT05117099)
- Testing
- Family Check-Up
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Anxiety, Sleep
Longterm Effects of a Biofield Patch on Anxiety, Sleep, and Energy
The goal for this clinical trial is to compare an active biofield non-transdermal skin patch to a placebo patch in people who frequently experience anxiety.
- Trial name
- NCT07353021
- Testing
- Active dermal patch
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Anxiety Disorder, Head and Neck Cancer
Study of Anxiety and Avoidance of Others in Patients Previously Treated for Head and Neck Cancer
RATIONALE: Patients who undergo treatment for head and neck cancer may become anxious and avoid contact with other people. Learning how cancer treatment may cause anxiety in patients with head and neck cancer may help improve the…
- Conditions
- Anxiety Disorder, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00483639
- Testing
- Medical chart review, Liebowitz Social Anxiety Scale and the Social Phobia and Anxiety Inventory, management of therapy complications
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Caloric Restriction, Body Composition
Long-Term Effects of Semaglutide on Body Composition and Performance in Running
Semaglutide, a GLP-1 receptor agonist, has demonstrated significant weight-loss effects in people with obesity and/or type 2 diabetes, but its impact on exercise performance among lean, fit athletes remains unknown.
- Conditions
- Caloric Restriction, Body Composition, Performance
- Trial name
- NCT07874932
- Testing
- Semaglutide (SEMA)
- Where
- Denmark
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Anaemia
Long Term Effect of Early Iron Supplementation and Psychosocial Stimulation on Growth and Development of Iron-deficient Anaemic Infants
1. Burden: Anaemia is a public health problem in our country. Fifty one percent young children aged 6 to 59 months are suffering from anaemia in Bangladesh (BDHS-2011) and the main cause of this problem is iron deficiency.
- Trial name
- NCT02801721
- Testing
- psycho social stimulation
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function
This study will evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a 6-month weight loss intervention and 12-months of follow-up on physical function, muscle mass, and weight loss…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT (NCT03074643)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, Carbohydrate supplement for months 0-6
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Air Pollution, mHealth Intervention
1/2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh
Almost 3 billion people worldwide, including 89% people in Bangladesh, are exposed to harmful household air pollutants (HAP) emitted from combustion of biomass (wood, agricultural residue, cow dung, etc.) fuel use for cooking.
- Conditions
- Air Pollution, mHealth Intervention, Cardiopulmonary Function, Immune Function
- Trial name
- GEOHealth-II (NCT05570552)
- Testing
- mHealth based behavioral change communication intervention
- Where
- Bangladesh
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Dust Mite Allergy, Allergic Rhinitis
Long-term Effect of a 3-month Supplementation With Holo-BLG on House Dust Mite Induced Allergic Rhinoconjunctivitis
The aim of the study is to investigate the long-term effect of a lozenge containing beta-lactoglobulin (BLG), iron, retinoic acid, zinc and polyphenols (holo-BLG) in people with allergic rhinoconjunctivitis caused by house dust…
- Trial name
- NCT04872868
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- Ecarf Institute GmbH
Obesity, Weight Loss
Obesity Treatment With LCD in Primary Health Care
The aim of this study is to evaluate if an internet-based CBT (Cognitive Behavioral Therapy) programme for weight stability after LCD (Low Calorie diet) treatment for obesity, can reduce weight gain and improve weight stability…
- Trial name
- LCD-KBT (NCT01608191)
- Testing
- CBT follow up
- Where
- Sweden
- Volunteers
- 174 people
- Sponsor
- Örebro County Council
Diabetes Mellitus, Type 2
Effects of Physical Activity Coaching on Health and Behaviour Parameters in Diabetic Persons
In this project the investigators like to develop a methodology to stimulate more physical activity in inactive diabetic persons by an adapted physical activity program.
- Trial name
- NCT02064335
- Testing
- Physical activity coaching
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Migraine
A Study to Evaluate the Tolerability of Botox and Topiramate or Botox and Placebo and Effect on Cognitive Efficiency
The purpose of this study is to evaluate sustained tolerability, quality of life, and change in cognitive efficiency following treatment with OnabotulinumtoxinA and daily topiramate vs.
- Trial name
- NCT01700387
- Testing
- onabotulinumtoxinA, Topiramate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cady, Roger, M.D.