Clinical trials: Effects, Longterm
Obesity
Long-term Effects of Bariatric Surgery
The primary objective of LABS-2 is to use standardized techniques and measures to assess the longer-term safety and efficacy of bariatric surgery by: 1. comparing post-surgical outcomes to pre-operative status 2.
- Trial name
- LABS-2 (NCT00465829)
- Where
- 9 sites in United States
- Volunteers
- 2,458 people
- Sponsor
- University of Pittsburgh
Periodontitis
Adjunctive Antimicrobial Therapy of Periodontitis: Long-Term Effects on Disease Progression and Oral Microbiological Colonization
The purpose of this study is to determine the size of the benefit of an adjunctive empiric antibiotic therapy compared to standard mechanical debridement and oral hygiene instructions in a representative sample of German…
- Trial name
- ABPARO-Studie (NCT00707369)
- Testing
- Amoxicillin and Metronidazole
- Where
- 8 sites in Germany
- Volunteers
- 540 people
- Sponsor
- University Hospital Muenster
Depression
A Long Term Effect of Collaborative Care on Depression Treatment in a Community Dwelling Elderly
Suicide is a significant cause of death in Korea. According to the report compiled by the Korea National Statistical Office, 24.8 victims of every 100,000 in 2007 (Korea National Statistical Office, 2008), which is higher…
- Trial name
- NCT01817244
- Testing
- care management
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- National Clinical Research Coordination Center, Seoul, Korea
HIV Infections
Long-term Effects of Highly Active Anti-Retroviral Therapy on HIV-Infected Children
This study will use the NIH-sponsored Women and Infants Transmission Study (WITS) and the Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2) HIV-infected pediatric cohorts to…
- Trial name
- NCT00260806
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 71 people
- Sponsor
- University of Miami
Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy
Long Term Effects of Enalapril and Losartan on Genetic Heart Disease
The human heart is divided into four chambers. One of the four chambers, the left ventricle, is the chamber mainly responsible for pumping blood out of the heart into circulation.
- Conditions
- Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy, Myocardial Ischemia
- Trial name
- NCT00001534
- Testing
- Losartan
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Nocturnal Enuresis
Nocturnal Enuresis and Rapid Maxillary Expansion
Nocturnal enuresis (NE) is the involuntary loss of urine that occurs only at night in children aged 5 years or more. NE is a common problem, affecting about 10% of school children.
- Trial name
- NERME (NCT02178826)
- Testing
- Rapid Maxillary Expansion
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University Hospital
Ledderhose Disease
Ledderhose Disease - Long Term Effects of Radiotherapy Treatment. LedRad LTE - Study
The aim of the LedRad LTE study is to determine the current complaints, late side effects and satisfaction of patients who were treated with radiotherapy for Ledderhose disease at least two years ago.
- Trial name
- NCT04229147
- Testing
- Radiotherapy
- Where
- Netherlands
- Volunteers
- 68 people
- Sponsor
- University Medical Center Groningen
Osteoporosis, Vertebral Fracture
Patient Education With or Without Physical Training or Mindfulness and Medical Yoga in Established Spinal Osteoporosis
In the present feasibility and pilot study we aim to investigate the effect and safety of patient education with or without additional physical training or mindfulness/medical yoga in patients with manifest spinal osteoporosis…
- Trial name
- NCT05227976
- Testing
- Patient education (Theory), Physical training, Mindfulness and medical yoga in group
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- University Hospital, Linkoeping
Multiple Sclerosis
Retrospective Observational Study About Long-term Effect of Fampridine in Patients With Multiple Sclerosis
Mobility problems in multiple sclerosis (MS) is a frequent symptom. It might appear in almost 93% of patients in the first 15 years of the disease, being a clear problem for their normal living.
- Trial name
- RETROFAM (NCT02966808)
- Testing
- cognitive and behavioural questionnaires
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Healthy, Brain Insulin Sensitivity
Long-Term Effects of Walnut Consumption on Brain Function
Rationale: Healthy foods, including mixed nuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Conditions
- Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function
- Trial name
- WalBrain (NCT07422220)
- Testing
- Walnuts
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Obstructive Sleep Apnea
Long-term Effects of Lipoabdominoplasty on Pulmonary Function and Sleep Apnea Risk in Obese Subjects
This study investigates the long-term effects of lipoabdominoplasty on pulmonary function and obstructive sleep apnea (OSA) risk in obese patients.
- Trial name
- NCT07029750
- Testing
- Lipoabdominoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Atlas University
Cushing Syndrome
Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma
Objective: To determine the metabolic effects of the adrenalectomy in subclinical Cushing's syndrome of adrenal incidentaloma. Methods: 234 subclinical cushing syndrome and adrenal incidentaloma will be randomly assigned into two…
- Trial name
- NCT01382420
- Testing
- surgery
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Samsung Medical Center
Skin-to-skin Contact
Skin-to-skin Contact in Healthy Term Infants
This is a prospective, double-blind, randomized controlled clinical trial study to investigate short- and long-term effects of mother-infant skin-to-skin contact in healthy term infants, in order to provide supporting data for…
- Trial name
- NCT06777524
- Testing
- skin-to-skin contact education
- Where
- 2 sites in South Korea
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Pain, Postoperative
US-guided Ilioinguinal Blocks Versus Local Infiltration
Injection of local anesthetic drugs is an effective way to freeze (block) nerves to achieve loss of sensation during surgery and satisfactory pain control afterwards.
- Trial name
- NCT01871181
- Testing
- Ilioinguinal block, Local infiltration
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Hamstring Tightness
IASTM vs. Static Stretching for Hamstring Tightness: Short- and Long-Term Effects
This study compares two treatments for people with tight hamstring muscles (the muscles at the back of the thigh): instrument-assisted soft tissue mobilization (IASTM) and static stretching.
- Trial name
- IASTM-HT (NCT07838844)
- Testing
- Instrument-Assisted Soft Tissue Mobilization, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- GÖKHAN MARAŞ
Short Bowel Syndrome
The Long-term Effect on Intestinal Absorption and Safety of Treatment With Glepaglutide in Patients With Short Bowel Syndrome
The purpose of this trial is to investigate the long-term effect of glepaglutide on the intestinal absorption, nutritional status of participants with Short Bowel Syndrome (SBS).
- Trial name
- EASE SBS 4 (NCT04991311)
- Testing
- Glepaglutide
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Zealand Pharma
Epiretinal Membrane
Epiretinal Fibrosis, Effect of Early Surgery
The goal of this randomized clinical trial is to investigate when it is optimal to treat the eye disease epiretinal fibrosis. Hypothesis: In a population of patients with symptomatic idiopathic epiretinal fibrosis and visual…
- Trial name
- epitell (NCT00902629)
- Testing
- Early surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Carpal Tunnel Syndrome
Platelet Rich Plasma for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT03184688
- Testing
- platelet rich plasma, Normal saline
- Where
- Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Knee Osteoarthritis
Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis
Knee pain is one of the most usual pain that commonly affects people especially in the late age. It can be caused by osteoarthritis, poor posture or sitting position, bad bending or improper lifting.
- Trial name
- NCT04818307
- Testing
- Macquarie Injury Management group, Mulligan Mobilization with Movement
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Leukemia, Myeloid, Acute, Acute Lymphoid Leukemia
Evaluation of Adverse Long-term Effects in Young Adult Survivors of Acute Leukemia
Taking into account the specificities of adolescent and young adult cancer patients led agencies (in particular the French National Cancer Institute INCa, through the last Cancer Plan), to initiate projects targeting this…
- Trial name
- LEA-JA (NCT02345915)
- Testing
- Blood sample, Electrocardiogram
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Institut Paoli-Calmettes