Clinical trials: Effects, Longterm
Head and Neck Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
RATIONALE: Tests that measure how much saliva is made, hearing, swallowing, voice function, and quality of life may improve the ability to plan treatment for patients with advanced head and neck cancer and may help doctors find…
- Conditions
- Head and Neck Cancer, Long-term Effects Secondary to Cancer Therapy in Adults, Oral Complications of Radiation Therapy, Radiation Toxicity
- Trial name
- NCT00415025
- Testing
- adjuvant therapy, management of therapy complications, quality-of-life assessment
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Oral Health, Quality of Life
The Long-term Effect on Oral Health Using a Powered Toothbrush in Individuals With Mild Cognitive Impairment
For this study, 213 individuals with Mild Cognitive Impairment were recruited. The study period ran from June 2018 to October 2021.
- Trial name
- NCT05939050
- Testing
- Powered toothbrush
- Where
- 2 sites in Sweden
- Volunteers
- 170 people
- Sponsor
- Blekinge Institute of Technology
Osteoporosis, Sarcopenia
Effect of Creatine Supplementation and Exercise on Bone Health
Osteoporosis is an important health problem, costing the Canadian health care system over $2 billion per year. Loss of bone mineral and bone fragility is especially prevalent in postmenopausal women.
- Trial name
- NCT02047864
- Testing
- Creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Covid19, MIS-C Associated With COVID-19
Pediatric COVID Outcomes Study (PECOS)
This is a multisite prospective observational study to evaluate the clinical sequelae of symptomatic and asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the pediatric population, including…
- Conditions
- Covid19, MIS-C Associated With COVID-19, MIS-C Multisystem Inflammatory Syndrome in Children, SARS-CoV2 Infection
- Trial name
- NCT04830852
- Where
- 2 sites in United States
- Volunteers
- 1,097 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
THE LEFT VENTRICULAR REMODELING AFTER MECHANICAL AORTIC VALVE REPLACEMENT
Long-Term Effects of Aortic Valve Mismatch
The real impact of the existence of an aortic valve mismatch after aortic valve replacement in various studies conducted so far is a source of controversy.
- Trial name
- NCT00854698
- Testing
- exercise training, subjects are asked to exercise during 20 or 30 minutes
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Strasbourg, France
Primary Progressive Aphasia(PPA)
Long Term Effect of Brain Stimulation in PPA
The goal of this clinical trial is to investigate the effect of non-invasive brain stimulation techniques in the progression of primary progressive aphasia for 6 months.
- Trial name
- RECONNECT-PLUS (NCT07158216)
- Testing
- TMS, tDCS
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital San Carlos, Madrid
Acquired Brain Injury
Long-term Effects of AAT in Patients With ABI
The aim of this study is to investigate weather patients treated with animal-assisted therapy show better socioemotional skills compared to treatment as usual.
- Trial name
- NCT03687671
- Testing
- Animal-assisted therapy, Treatment as usual
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Swiss Tropical & Public Health Institute
Kidney Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
Warm Ischemia or Cold Ischemia During Surgery in Treating Patients With Stage I Kidney Cancer
RATIONALE: Warm ischemia is the clamping of blood vessels without cooling the kidney. Cold ischemia is the clamping of blood vessels with kidney cooling.
- Conditions
- Kidney Cancer, Long-term Effects Secondary to Cancer Therapy in Adults, Perioperative/Postoperative Complications, Urinary Complications
- Trial name
- NCT00743236
- Testing
- cold ischemia procedure, warm ischemia procedure
- Where
- 8 sites in United States
- Volunteers
- 1 people
- Sponsor
- Wake Forest University Health Sciences
Osteoporosis
Calcium and Bone Mass in Young Females
We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls.
- Trial name
- NCT00000402
- Testing
- Calcium
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Contact Lens Care
Effect of Multi-Purpose Solutions on Ex-Vivo Wetting Angles
To clinically evaluate the effect of a new multi-purpose disinfecting solution compared to a marketed multi-purpose solution on wettability of soft contact lenses worn for 30 days.
- Trial name
- NCT00383201
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Pectus Carinatum, Quality of Life
Health-related Quality of Life in Patients Undergoing Surgery for Pectus Carinatum
The purpose of the study is to assess changes in health-related quality of life in patients undergoing surgical correction of pectus carinatum.
- Conditions
- Pectus Carinatum, Quality of Life, Pain, Postoperative, Somatosensory Disorders
- Trial name
- HRQoL (NCT01692392)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Traumatic Brain Injury, Blast Injuries
Long-Term Effects of Repetitive, Low-Level Blast Exposure on Special Operations Forces Service Members
This is a pilot study to identify biomarkers that individually, and in combination, demonstrate the greatest sensitivity to repetitive, low-level blast exposure (RLLBE) neurotrauma in Special Operations Forces (SOF) personnel.
- Trial name
- ReBlast (NCT05183087)
- Testing
- 3T Connectome MRI, 7 Tesla MRI, TSPO PET
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea, High Flow Nasal Canula
Long-term Effect of High Flow Nasal Canula Therapy on Obstructive Sleep Apnea
Patients meeting the criteria of obstructive sleep apnea were included, and all patients signed informed consent, which met the requirements of the ethics Committee of our unit. All subjects were hospitalized patients.
- Conditions
- Obstructive Sleep Apnea, High Flow Nasal Canula, Continuous Positive Airway Pressure Ventilation
- Trial name
- HFNC (NCT05549310)
- Testing
- CPAP, high-flow nasal canula oxygen therapy
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Qilu Hospital of Shandong University
Bronchiectasis
Short-and Long-term Effects of a Home-based Rehabilitation Program in Patients With Bronchiectasis
This study will investigate the short-and long-term effects of the home-based pulmonary rehabilitation on peripheral muscle strength, functional capacity and quality of life in patients with bronchiectasis.
- Trial name
- NCT02731482
- Testing
- Training Group, Control Group
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- University of Nove de Julho
Anxiety Disorder, Cancer Survivor
Quality of Life in Younger Leukemia and Lymphoma Survivors
RATIONALE: Collecting information about the effect of hematologic cancer and its treatment on quality of life may help doctors learn more about the disease and plan the best treatment.
- Conditions
- Anxiety Disorder, Cancer Survivor, Fatigue, Leukemia
- Trial name
- NCT00956475
- Testing
- telephone-based intervention, questionnaire administration, assessment of therapy complications
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Case Comprehensive Cancer Center
Lifestyle, Quality of Life
Long Term Effects of a Structured Lifestyle Program
The aim of the present study was to describe a structured intervention to reduce cardiovascular risk in a clinical setting and to study the effects of the program on lifestyle habits and quality of life in individuals at risk…
- Trial name
- NCT02744157
- Testing
- Longterm effects after a structured lifestyle program
- Volunteers
- 102 people
- Sponsor
- Karolinska University Hospital
Long Covid19
Long-term Effects of SARS-CoV-2 on the Central Nervous System and One-year Follow-up of "Long COVID-19" Patients
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the seventh coronavirus known to infect humans, and causing coronavirus disease 2019 (COVID-19). .
- Trial name
- NCT05492292
- Testing
- Perfusion brain scintigraphy imaging
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Brugmann University Hospital
Parkinson's Disease, Depression
Long Term Follow Up KET-PD
The purpose of this study is to examine a) the longer-term effects of ketamine for treating depression in Parkinson's disease (PD) and b) the effects of CBT on maintaining the effects of ketamine.
- Trial name
- NCT06164756
- Testing
- Cognitive Behavior Therapy (CBT), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Yale University
Alcoholic Liver Disease
Long Term Effect of Aggressive Nutritional Management on Survival in Patients With Alcoholic Liver Disease
Patient found to be malnourished after the nutritional evaluation would be randomized in the two groups of the study. The control group would receive standard nutritional counseling from a trained dietician where as those in the…
- Trial name
- NCT02140294
- Testing
- Polymeric nutritional supplements, Standard Nutrional Treatment
- Where
- India
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
Breast Cancer, Cognitive/Functional Effects
Fatigue Caused by Chemotherapy in Women Who Have Undergone Surgery for Breast Cancer and in Healthy Volunteers
RATIONALE: Gathering information over time from women undergoing chemotherapy for breast cancer may help doctors learn more about mental and physical fatigue caused by treatment.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Fatigue, Long-term Effects Secondary to Cancer Therapy in Adults
- Trial name
- NCT00909662
- Testing
- assessment of therapy complications, cognitive assessment, fatigue assessment and management
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center