Clinical trials: Effects, Longterm
Risk Factors, Complication of Surgical Procedure
ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.
- Conditions
- Risk Factors, Complication of Surgical Procedure, Complication of Treatment, Complication of Anesthesia
- Trial name
- ACUTE (NCT05195697)
- Testing
- Observational study of different treatments and time to treatment
- Where
- Sweden
- Volunteers
- 3,000 people
- Sponsor
- Region Skane
BPH
The Long Term Effects of Alfuzosin(Xatral XL) in Lower Urinary Tract Symptoms(LUTS)/BPH Patients
Benign prostatic hyperplasia (BPH) is a common condition among older men. The efficacy of α1-blockers for treating BPH has been well documented and they are recommended for the treatment of BPH by clinical guidelines.
- Trial name
- NCT00696761
- Testing
- Alfuzosin
- Volunteers
- 232 people
- Sponsor
- Asan Medical Center
Healthy
Immediate and Long-term Effects of an Adaptation of the "Balloon-blowing Exercise"
Despite the literature evidence that the "balloon-blowing exercise" improves the pulmonary function as a long-term effect, this exercise has not yet been studied or tested experimentally, meaning that there are no specific and…
- Trial name
- NCT04737824
- Testing
- An adaptation of the "balloon-blowing" exercise, An adaptation of the "balloon-blowing" exercise for seven weeks, three times a week, at home
- Where
- Portugal
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Appetite, Dietary Intake
Short and Long-Term Effects of Prebiotic, Probiotic and Synbiotic on Appetite and Dietary Intake
Prebiotics and probiotics are thought to play a role in appetite control and body weight regulation; but little is known about this topic.
- Conditions
- Appetite, Dietary Intake, Body Weight
- Trial name
- NCT04212546
- Testing
- Synbiotic test drink, Control drink
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Obstructive Pulmonary Disease
Long-term Effect of an Health Education Program on Daily Physical Activity in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Main objective: To compare the level of physical activity (PAL) at 12 months in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) between those who completed a health education program and those…
- Trial name
- EA-EPOC (NCT02924870)
- Testing
- Health education program, Conventional management
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Hospital Universitario La Paz
Colorectal Cancer, Fatigue
Patient-Reported Outcomes in Long-Term Survivors of Colon and Rectal Cancers
RATIONALE: Learning about quality of life, symptoms, and health behaviors in colorectal cancer survivors may help to determine the long-term effects of colon and rectal cancer treatments and may help to improve the quality of…
- Conditions
- Colorectal Cancer, Fatigue, Long-term Effects Secondary to Cancer Therapy in Adults, Pain
- Trial name
- NCT00410579
- Testing
- Telephone interview
- Where
- 200 sites in United States
- Volunteers
- 744 people
- Sponsor
- NSABP Foundation Inc
Cognitive/Functional Effects, Colorectal Cancer
Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer
RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on brain function may help doctors plan cancer treatments.
- Conditions
- Cognitive/Functional Effects, Colorectal Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
- Trial name
- NCT00410618
- Testing
- cognitive assessment, magnetic resonance imaging, management of therapy complications
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Arizona
Cannabis Dependence
Social and Emotional Brain Function in Cannabis Users
The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a…
- Trial name
- NCT02711371
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cystic Fibrosis
Continuous Azithromycin in Cystic Fibrosis Patients Beyond Two Years
Azithromycin is an antibiotic currently prescribed continuously in cystic fibrosis patients. It was shown that this treatment taken every day or every week for 12 months, can improve the respiratory state of patients.
- Trial name
- AZITHRO (NCT02803944)
- Testing
- Azithromycin
- Where
- France
- Volunteers
- 2,055 people
- Sponsor
- Hospices Civils de Lyon
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Irinotecan and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Long-term Effects Secondary to Cancer Therapy in Adults, Long-term Effects Secondary to Cancer Therapy in Children
- Trial name
- NCT00389584
- Testing
- irinotecan hydrochloride, cognitive assessment, management of therapy complications
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Chronic Kidney Disease Requiring Chronic Dialysis
Potential Benefits of Expanded Hemodialysis in Prevention of Sarcopenia
The current study will investigate whether long term implementation of expanded hemodialysis (HDx) will effectively decrease serum levels of large uremic toxins and ameliorate progression of sarcopenia in patients with chronic…
- Trial name
- NCT04585607
- Testing
- A medium cut-off dialyzer (Theranova) will be used for HDx., A synthetic high-flux dialyzer (Polyflux)
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Gangnam Severance Hospital
Prediabetic State
Clinical Study to Assess the Long-term Effect of Pep2Dia® on Glucose Homeostasis in Prediabetic Subjects
The goal is to assess the long-term effect of Pep2Dia® compared to placebo intake on blood glucose homeostasis. Respective improvements will be assessed by changes in glycated haemoglobin (HbA1c) before and after the 12-weeks…
- Trial name
- NCT05391854
- Testing
- Pep2dia
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ingredia S.A.
Fibrin Sealant, Haemostasis
Assessment of Long-term Effects of Tachosil
This study aimed to analyse the long-term effects of a carrier-bound fibrin sealant (CBFS) after abdominal surgery by following up patients years after application.
- Trial name
- NCT05986201
- Testing
- TachoSil®
- Volunteers
- 40 people
- Sponsor
- University of Catania
Coronary Artery Disease, Chronic Heart Failure
Long-tErm Effects of Enhanced eXternal CountErpuLsation
Enhanced external counterpulsation (EECP) is an effective non-invasive treatment in patients with coronary artery disease (CAD) which complicated by chronic heart failure (CHF).
- Trial name
- EXCEL (NCT05913778)
- Testing
- Enhanced external counterpulsation
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gait, Hemiplegic
Implanted Drop Foot Stimulator for Hemiparetic Patients
The aim of this study is to investigate the effects of the implantable drop foot stimulator "ActiGait" (Ottobock Health Care, Duderstadt, Germany) on gait in hemiparetic patients.
- Trial name
- NCT03447717
- Testing
- ActiGait
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Long-term Effects Secondary to Cancer Therapy in Children, Neurotoxicity
Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201
RATIONALE: Assessing the effects of methotrexate on brain function in children may improve the ability to plan treatment and decrease side effects.
- Trial name
- NCT00028509
- Testing
- management of therapy complications
- Where
- 26 sites in United States, Canada
- Volunteers
- 66 people
- Sponsor
- Children's Oncology Group
Sickle Cell Disease, Hemolytic Anemia
Long Term Effects of Erythrocyte Lysis
In this prospective observational trial, participants with chronic hemolysis will be assessed with echocardiogram for elevated tricuspid jet velocity and other evidence of pulmonary hypertension.
- Trial name
- NCT00842621
- Testing
- Clinical Evaluations, Laboratory Studies
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- St. Jude Children's Research Hospital
Hypertension
Evaluation of the Long-term Safety and Tolerability of Metoprolol Versus Nebivolol in Patients With Hypertension
The purpose of this study is to evaluate long-term safety,tolerability and blood pressure effects of metoprolol versus nebivolol in patients with hypertension.
- Trial name
- NCT00142584
- Testing
- Nebivolol (NEB), Metoprolol (MET)
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- Mylan Bertek Pharmaceuticals
Anxiety
Perioperative Pregabalin Use, Rehabilitation, Pain Outcomes and Anxiety Following Hip Surgery
Pain prior to surgery is of particular concern in patients undergoing total hip arthroplasty (THA) since it is the most important predictor of pain and poor function 2-3 years after surgery.
- Trial name
- RCT (NCT00762099)
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 184 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prostate Cancer
The Long Term Effect of MRI Before Radical Prostatectomy.
A randomized clinical trial conducted by Oslo University Hospital between 2010 and 2012 included 438 patients with prostate cancer to the non-MRI group (216) or the MRI group (222) before robot-assisted radical prostatectomy…
- Trial name
- NCT06429878
- Testing
- Biparametric prostatic MRI
- Volunteers
- 438 people
- Sponsor
- Oslo University Hospital