Clinical trials: Effects, Longterm
Breast Cancer, Depression
Multimedia Educational Program for Patients With Early-Stage Prostate Cancer or Breast Cancer
RATIONALE: A multimedia educational program may help patients with newly diagnosed prostate cancer and breast cancer reduce distress, make informed treatment decisions, and improve quality of life.
- Conditions
- Breast Cancer, Depression, Long-term Effects of Cancer Treatment, Prostate Cancer
- Trial name
- NCT00830635
- Testing
- educational intervention, informational intervention, internet-based intervention
- Where
- 3 sites in United States
- Volunteers
- 1,800 people
- Sponsor
- University of Colorado, Denver
Pulmonary Disease, Chronic Obstructive
Survival Of Subjects With Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to see if fluticasone 500mcg/salmeterol 50mcg can improve the survival of subjects with COPD and also assess the long term safety profile of this drug.
- Trial name
- NCT00268216
- Testing
- Salmeterol 50mcg/ Fluticasone Propionate 500mcg
- Where
- 459 sites in United States, Argentina and 42 more
- Volunteers
- 6,228 people
- Sponsor
- GlaxoSmithKline
Preterm Birth, Child Development
Omega Tots Long Term Follow-up
This is a continuation study to the Omega Tots trial (NCT01576783). The purpose of this study is to follow-up with participants of the original study to determine the long-term effect a daily fatty acid dietary supplement taken…
- Trial name
- NCT05191823
- Testing
- Docosahexaenoic Acid + Arachidonic Acid (DHA+AA)
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- Sarah Keim
Carcinoma, Non-Small-Cell Lung, Surgery
Dexamethasone, Flurbiprofen Axetil and Long-term Survival After Lung Cancer Surgery
Surgical resection is the first choice treatment for patients with non-small-cell lung cancer. Despite of advances in surgical techniques, the long-term survival rate of postoperative patient is far from optimal.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Surgery, Dexamethasone, Flubiprofen Axetil
- Trial name
- NCT03172988
- Testing
- Dexamethasone, Normal saline, Flurbiprofen axetil
- Where
- 2 sites in China
- Volunteers
- 126 people
- Sponsor
- Peking University First Hospital
Osteopenia or Osteoprosis
Long-term Effect of Electromagnetic Field in Treatment of Patients With Osteopenia or Osteoporosis
Osteoporosis is the most prevalent metabolic bone disease. Although osteoporosis is widely considered to be much more prevalent in women approximately 39% of new osteoporotic fractures estimated to have occurred worldwide in 2000…
- Trial name
- NCT04608162
- Testing
- Pulsed Electromagnetic Field (PEMF), Exercise Program
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Umm Al-Qura University
Lymphoma, Follicular
A Study of Long-Term Rituximab (MabThera) Maintenance Therapy in Participants With Advanced Follicular Lymphoma
This study will evaluate the efficacy, safety, and tolerability of long-term maintenance therapy with rituximab in participants with advanced follicular lymphoma who have had a positive response to first-line treatment with a…
- Trial name
- NCT02569996
- Testing
- Rituximab
- Where
- 21 sites in Hungary
- Volunteers
- 124 people
- Sponsor
- Hoffmann-La Roche
Heart Failure
Study of Dietary Intervention Under 100 MMOL in Heart Failure
This study aims to identify the relationship between a low-sodium diet and neurohormonal and clinical status in stable chronic HF patients.
- Trial name
- SODIUM-HF (NCT01480401)
- Testing
- low-sodium diet (1500 mg daily)
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
IgA Nephropathy
Effect of Tonsillectomy on Longterm Renal Outcome of IgA Nephropathy
The effect of tonsillectomy therapy on IgA nephropathy is still controversial.Few prospective,randomized investigations have examined how tonsillectomy affects the shortterm and longterm renal outcome of IgA nephropathy.This is A…
- Trial name
- NCT02471599
- Testing
- tonsillectomy, non-tonsillectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
RATIONALE: Donepezil may decrease the side effects caused by radiation therapy to the brain. PURPOSE: This clinical trial is studying how well donepezil works in treating young patients with primary brain tumors previously…
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Long-term Effects Secondary to Cancer Therapy in Children, Neurotoxicity
- Trial name
- NCT00452868
- Testing
- Donepezil
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Wake Forest University Health Sciences
Congenital Heart Disease
Fontan Circulation and Cardiopulmonary Function: Prognostic Factors, Hemodynamics and Long-term Effects
Cross-sectional study of a national cohort of adolescents with univentricular congenital heart defects and Fontan type palliation.
- Trial name
- NCT02378857
- Where
- Norway
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Myocardial Infarction, Prevention Harmful Effects
Intensive Prevention Program After Myocardial Infarction
It is unknown, if a modern prevention program, including intense nurse-coordinated education sessions, regular telephone contacts and a telephone hotline for 12 months, significantly reduces cardiovascular risk factors, clinical…
- Trial name
- IPP (NCT01896765)
- Testing
- Intensive Prevention Program, Standard medical and interventional therapy
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Herzzentrum Bremen
Hypertension With Complications and Secondary Hypertension, Overweight and Obesity
Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Cardiovascular diseases (CVD) represent the most frequent cause of death among the elderly population. Hypertension, unfavorable lipid profile, obesity and physical inactivity are among the main risk factors for CVD.
- Conditions
- Hypertension With Complications and Secondary Hypertension, Overweight and Obesity, Lipid Metabolism Disorders, Sarcopenia
- Trial name
- NCT01874132
- Testing
- Exercise training
- Where
- Portugal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Trás-os-Montes and Alto Douro
Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Premature Baby 26 to 32 Weeks
Comparison of Two Early Treatments for Premature Babies and Their Effects Over Time
According to the latest World Health Organization report, prematurity is a major health issue, recognized as a significant vulnerability factor contributing to the emergence of neurodevelopmental disorders.
- Conditions
- Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Premature Baby 26 to 32 Weeks, Premature Baby 33 to 36 Weeks, Premature Between 32 and 36 Weeks of Amenorrhoea
- Trial name
- PREMOTSENS (NCT07261046)
- Testing
- ATVV (Auditory, Tactile, Visual and Vestibular stimulation), Singing
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elsan
Chronic Obstructive Pulmonary Disease
Effects of Inhaled Corticosteroids on Sputum Bacterial Load in COPD
Exacerbations are important events in the natural history of chronic obstructive pulmonary disease (COPD). Beside the acute (and prolonged) clinical impact, there is evidence that exacerbations negatively affect the natural…
- Trial name
- NCT01213693
- Testing
- Salmeterol/Fluticasone combination, Salmeterol
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Università degli Studi di Ferrara
To Assess Long-term Effects of COVID-19 in Patients Who Were Affected With COVID -19
Assessment of Long-term Effects (Complications) of COVID-19 in the Southern Part of Bangladesh - a Retrospective Observational Study.
An outbreak of the novel coronavirus nCoV-19 (SARS-CoV-2), responsible for the coronavirus disease-19 (COVID-19), was first detected in Hubei province, Wuhan, China, on December 31, 2019.
- Trial name
- NCT04987736
- Testing
- RT-PCR
- Where
- Bangladesh
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Sher-E-Bangla Medical College
Age Related Maculopathy
Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation for Two More Years (LUTEGA 2)
The primary objective of LUTEGA 2 is it to determine the long term effect (about 2 more years after LUTEGA 1, NCT00763659) of the supplementation with a fixed combination of lutein/zeaxanthin and omega-3- fatty acids in two…
- Trial name
- NCT01648660
- Testing
- Lutein/ Zeaxanthin + Omega- 3- Fatty Acids
- Volunteers
- 80 people
- Sponsor
- University of Jena
Age Related Maculopathy
Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients (LUTEGA)
The primary objective of LUTEGA is it to determine the long term effect (about 1 year) of the supplementation with a fixed combination of lutein/zeaxanthin and omega-3- fatty acids on the optical density (OD) of macular pigment…
- Trial name
- LUTEGA (NCT00763659)
- Testing
- Lutein/ Zeaxanthin + Omega-3-FA
- Where
- Germany
- Volunteers
- 172 people
- Sponsor
- University of Jena
Hyperhidrosis
Long Term Results of the Use of Oxybutynin for the Treatment of Hyperhidrosis
Evaluate the long term efficacy and side effects of oxybutynin in the treatment of hyperhidrosis.
- Trial name
- NCT01956591
- Testing
- Oxybutynin
- Where
- Brazil
- Volunteers
- 1,100 people
- Sponsor
- Hospital Israelita Albert Einstein
Atrium; Beat, Echocardiography
Chronic Ibrutinib Therapy Effect on Left Atrial Function
Ibrutinib is an irreversible Bruton tyrosine-kinase inhibitor. In prospective studies, the ibrutinib efficacy in the treatment of various B-cell malignancies was established.
- Conditions
- Atrium; Beat, Echocardiography, Physiology, Therapy Adverse Effect
- Trial name
- CITE-LA (NCT03751410)
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Sestre Milosrdnice
Actinic Keratosis
Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses
This clinical trial serves the purpose to compare the long-term effects of a treatment of actinic keratosis - your skin disorder - using Aldara® 5% cream or Solaraze® 3% gel on the face or the scalp.
- Trial name
- LEIDA (NCT00777127)
- Testing
- Imiquimod, Diclofenac
- Where
- 26 sites in Austria, France and 1 more
- Volunteers
- 258 people
- Sponsor
- MEDA Pharma GmbH & Co. KG