Clinical trials: Effects, Longterm
Contact Lens Care
Effect of Multi-Purpose Solutions on Ex-Vivo Wetting Angles
To clinically evaluate the effect of a new multi-purpose disinfecting solution compared to a marketed multi-purpose solution on wettability of soft contact lenses worn for 30 days.
- Trial name
- NCT00383201
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Protrusion of Lumbar Intervertebral Disc
Deep Needling Protrusion of Lumbar Intervertebral Disc the Five Acupoints
Compare the curative effects of electroacupuncture deep needling difference in efficacy of the conservative treatment for lumbar five point therapy and routine western medicine, to explore the efficacy and superiority, open a new…
- Trial name
- NCT02824887
- Testing
- Electro-acupuncture, Conventional treatment of Western Medicine
- Volunteers
- 175 people
- Sponsor
- The Third Affiliated Hospital of Beijing University of Chinese Medicine
Breakfast, Appetitive Behavior
High Protein Breakfast on Weight Management and Glycemic Control in 'Breakfast-skipping' Teens
75 overweight, habitual 'breakfast-skipping' adolescents will complete the following long-term, randomized controlled trial. Participants will be randomly assigned to the following breakfast treatments: 350 kcal high protein…
- Trial name
- NCT03134014
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Purdue University
Allergy in Children
Long Term Effect of AIT in Children
The present study will investigate the long term effect of allergen immunotherapy in a real-life study in children with allergy undergoing subcutaneous or sublingual immunotherapy with grass pollen, birch, house dust mites or…
- Trial name
- NCT06421415
- Testing
- Allergen Immunotherapy Extract
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Mental Health Literacy, Waitlist
Long-term Effect of Online Mental Health Literacy Training
The purpose of this study is to assess the effectiveness over time of an online mental health in sport module in improving mental health literacy, stigma, and help-seeking behaviors in a sample of Brock student-athletes.
- Trial name
- NCT04645784
- Testing
- Supporting Student-Athletes Mental Wellness
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brock University
Melanoma
A Retrospective Observational Study on the Long-term Effects of Ipilimumab-treated Pediatric Participants in the Dutch Melanoma Treatment Registry (DMTR)
This is an observational, national, retrospective study consisting of pediatric patients with advanced (spread or unremoveable) melanoma identified in the DMTR in the Netherlands
- Trial name
- NCT04196452
- Testing
- Ipilimumab
- Volunteers
- 10 people
- Sponsor
- Bristol-Myers Squibb
HIV Infections, Sexually Transmitted Diseases
Exploring Long-term Risks and STI Prevalence in Pre-Exposure Prophylaxis Users in Gironde, France
SAFER-PrEP investigates the long-term impact of Pre-Exposure Prophylaxis (PrEP) on risky sexual behaviors and Sexually Transmitted Infection (STI) prevalence among users in Aquitaine.
- Trial name
- SAFER-PrEP (NCT06600087)
- Testing
- Questionnaire
- Where
- 8 sites in France
- Volunteers
- 248 people
- Sponsor
- University Hospital, Bordeaux
Overweight
Short- and Long-term Health Effects of a Residential Stay in a Danish Christmas Seal Home.
The purpose of the study is: (1) to evaluate the short-term effects of a 10-week residential stay in a Danish Christmas Seal Home on health, physical fitness, physical activity level, learning, sleep and well-being; (2) to…
- Trial name
- NCT03647007
- Testing
- FIFA 11 for health
- Where
- 2 sites in Denmark
- Volunteers
- 614 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Breast Cancer, Cognitive/Functional Effects
Fatigue Caused by Chemotherapy in Women Who Have Undergone Surgery for Breast Cancer and in Healthy Volunteers
RATIONALE: Gathering information over time from women undergoing chemotherapy for breast cancer may help doctors learn more about mental and physical fatigue caused by treatment.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Fatigue, Long-term Effects Secondary to Cancer Therapy in Adults
- Trial name
- NCT00909662
- Testing
- assessment of therapy complications, cognitive assessment, fatigue assessment and management
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Peptic Ulcer, Dyspepsia
HEP-FYN 12-Years Follow-up
Aims: 1. Evaluate the long-term effect of screening and eradication of Helicobacter Pylori on the prevalence of dyspepsia, and, as secondary outcomes, to assess the effect on dyspepsia related health-care consumption and quality…
- Conditions
- Peptic Ulcer, Dyspepsia, Reflux
- Trial name
- NCT02001727
- Testing
- 13C-Urea breath test for Helicobacter Pylori, Questionaire
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cardiotoxicity, Anthracycline Related Cardiotoxicity in Breast Cancer
ANTthracycline-induced Inflammation and OXidative Stress: 10-year Follow-up
The goal of this observational study is to learn about the long-term effects of anthracycline chemotherapy on inflammation, oxidative stress, and heart function in adult women with breast cancer.
- Conditions
- Cardiotoxicity, Anthracycline Related Cardiotoxicity in Breast Cancer, Breast Cancer
- Trial name
- ANTIOX-10 (NCT07680855)
- Volunteers
- 17 people
- Sponsor
- University of Chile
Stroke
Long Term Effects of Action Observation Therapy and Mirror Therapy on Upper Limb Functions
There will be a long term effects of action observation therapy and mirror therapy on upper limb functional outcomes after subacute stroke.
- Trial name
- NCT06027125
- Testing
- Action observation Therapy, Mirror Therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Arthritis,Rheumatoid
Long Term Effects of an Early Response to Certolizumab Pegol (CZP, Cimzia®) in Rheumatoid Arthritis (RA) Patients
To determine if early clinical response at 12 weeks to Certolizumab Pegol (CZP, Cimzia ®) therapy in adult Rheumatoid Arthritis (RA) patients is a predictor of better long term clinical response at 18 months compared with a lack…
- Trial name
- RA-PROACTIVE (NCT01288287)
- Where
- 22 sites in Ireland, United Kingdom
- Volunteers
- 149 people
- Sponsor
- UCB Pharma
Breast Cancer, Body Weight Change
The Study is Observational and Retrospective: Lifestyle, BMI and Activity Physical.
The goal of this observational-retrospective study is to learn about the long-term effects of a lifestyle intervention inclusive of dietary counselling and physical activity advice, on body weight in female breast cancer…
- Trial name
- Lifestyle (NCT06866093)
- Testing
- Lifestyle
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- National Cancer Institute, Naples
Carpal Tunnel Syndrome
The Effect of Combined PRP and ESWT for Carpal Tunnel Syndrome
The platelet rich plasma (PRP) and extracorporeal shock wave therapy (ESWT) are new and potential treatment for patients with kinds of musculoskeletal disorders.
- Trial name
- NCT02800200
- Testing
- Platelet rich plasma, shock wave
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Acquired Brain Injury
Long-term Effects of AAT in Patients With ABI
The aim of this study is to investigate weather patients treated with animal-assisted therapy show better socioemotional skills compared to treatment as usual.
- Trial name
- NCT03687671
- Testing
- Animal-assisted therapy, Treatment as usual
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Swiss Tropical & Public Health Institute
Multiple Sclerosis
Controlled High Risk AVONEX® Multiple Sclerosis Prevention Study In Ongoing Neurological Surveillance
Phase IV, multi-center, non-treatment, observational, registry study to determine long term effects of AVONEX® therapy on EDSS, MRI, QoL, and cognition.
- Trial name
- CHAMPIONS CONT (NCT01156298)
- Where
- United States
- Volunteers
- 383 people
- Sponsor
- Biogen
Hospice and Palliative Care Nursing, Terminally Ill Patients
The Short-Term and Long-Term Effects of Providing Mechanical Bath in Terminally Ill Patients
Providing mechanical bathing (MB) is a commonly used strategy to maintain cleanness and comfort in patients with terminally illness. However, extra devices, costs, and human resources are required for such service.
- Trial name
- NCT06620146
- Testing
- mechanical bathing
- Where
- Taiwan
- Volunteers
- 245 people
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus
Diabetic Autonomic Neuropathy and Left Ventricular Function
Purpose: To investigate the effect of Quinapril (Q) or Losartan (L) or their combination on definite Diabetic Autonomic Neuropathy (DAN) and left ventricular systolic and diastolic function (LVF) over a period of 4 years.
- Trial name
- DANEL (NCT05713396)
- Testing
- Quinapril, Losartan, Quinapril + Losartan
- Where
- Greece
- Volunteers
- 59 people
- Sponsor
- AHEPA University Hospital
Low Back Pain
Clinical Trial Examining the Short and Long-term Effect of Myofascial Trigger Points Injection in Low Back Pain Patients
The objective of this study is to examine the short and long-term effect of myofascial trigger point injections with either a local anesthetic or saline in patients with chronic low back pain presenting with myofasical pain…
- Trial name
- NCT01520415
- Testing
- Bupivacaine, Saline
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Yoram Shir