Clinical trials: Efficacy
Allergy
Effectiveness of Mediterranean Diet Intervention in Pregnant Women
There has been an increase in asthma and allergic disease prevalence, especially in children. Given the high prevalence, and the associated high disease burden and costs, there is an urgent need to identify effective strategies…
- Trial name
- NCT01634516
- Testing
- Dietary support, No dietary support
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heriot-Watt University
Unrecognized Condition
Comparison of Bowel Cleansing Efficacy Between Same-day Dose Versus Split Dose
Split dose bowel cleansing is recommended method for colonoscopy. For afternoon colonoscopy, same-day dose of bowel cleansing is alternative option. Recently, same-day bowel cleansing for morning colonoscopy was validated.
- Trial name
- NCT03315949
- Testing
- Polyethylene Glycol (PEG)
- Where
- South Korea
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Incheon St.Mary's Hospital
Use of Ambient AI Scribes, Patient-Phyisican Interaction
Assessing the Efficacy and Impact of Ambient AI Scribes in Healthcare
The goal of this clinical trial is to assess the impacts of ambient AI scribes on the workload and burnout in physicians who see patients in a clinic setting at least twice in a week, as well as the impacts on patient-physician…
- Conditions
- Use of Ambient AI Scribes, Patient-Phyisican Interaction, Physician Workload, Physician Burnout
- Trial name
- NCT07113938
- Testing
- Ambient AI Scribe
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Kolon Kanseri
Positive Psychotherapy Balance Model Based Psychoeducation for Caregivers of Oncology Patients
In this study, positive psychotherapy balance model applied to individuals caring for oncology patients the effect of psychoeducation intervention on balanced life, psychological well-being and self-efficacy.
- Trial name
- NCT06498258
- Testing
- Pozitif Psikoterapi Denge Modeli Temelli Psikoeğitim
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Servet CİHAN
Oncology, Education
Escape Room Game in Oncology Nursing
This research will be conducted to evaluate the effect of the escape room game activity applied to nursing students taking oncology nursing courses on their academic self-efficacy and critical thinking motivation.
- Trial name
- NCT06181058
- Testing
- escape room game
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Healthy Persons
Ultrasound Imaging of the Larynx and Diaphragm During NIV and Cough Assist
The study examines if diagnostic ultrasound imaging of larynx and diaphragm can be as accurate as transnasal fiberoptic laryngoscopy in visualizing the larynx during NIV and Mechanically Assisted Cough interventions.
- Trial name
- NCT04586855
- Testing
- Diagnostic Ultrasound, Transnasal Fiberoptic Laryngoscopy
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Movement Disorders
Effectiveness of Vojta Therapy in Motor Development of Preterm Children
Justification: Prematurely born children have an increased prevalence of neurodevelopment problems in the first two years. Knowledge regarding the effects of early intervention programs is essential to the follow up of these…
- Trial name
- NCT01838278
- Testing
- Vojta Physiotherapy Method
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Pulmonary Embolism
US Pivotal Clinical Study of the Adient Absorbable Filter for the Prevention of Pulmonary Embolism
The objective of the study is to evaluate the safety and efficacy of the Adient absorbable filter for the prevention of pulmonary embolism (PE: blood clot in the lungs).
- Trial name
- NCT05127915
- Testing
- Adient absorbable filter + best practice VTE prophylaxis, best practice VTE prophylaxis
- Where
- 2 sites in United States
- Volunteers
- 854 people, healthy volunteers welcome
- Sponsor
- Adient Medical
Atrophic Acne Scar
A Study to Evaluate the Efficacy of ELAPR002f in Females and Males With Atrophic Acne Scars
The study is designed to evaluate the efficacy of two formulations of a cross-linked tropoelastin matrix given the product codes ELAPR002f (collectively referred to as ELAPR or ELAPR002) for the treatment of rolling atrophic acne…
- Trial name
- NCT03056235
- Testing
- ELAPR002f, Saline
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elastagen Pty Ltd
Contraception, Female Contraception
A Study to Evaluate the Efficacy and Safety of DR-102 for the Prevention of Pregnancy
This is an open-label, single treatment study. All subjects will receive 12 months of oral contraceptive therapy with DR-102. Study participants will receive physical and gynecological exams, including Pap smear.
- Trial name
- NCT01178125
- Testing
- DR-102
- Where
- 62 sites in United States, Israel
- Volunteers
- 2,858 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Neck Pain
Self-Mobilization Versus Kinesio-Taping on the Cervical Region in Electronic Device Users
The purpose of this clinical trial is to compare the effectiveness of kinesio-taping versus self-mobilization applied to the cervical region of long-duration electronic device users.
- Trial name
- NCT05717868
- Testing
- Kinesiology taping, Self-mobilization
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
This single center study will investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving DH compared with a standard fluoride dentifrice after short term use.
- Trial name
- NCT02924350
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United Kingdom
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Microbiota-related Disease, Oral Hygiene
Interdental Hygiene Methods in Young Adults
Oral health is essential for overall well-being and systemic health. A key factor in preserving this health is maintaining the balance of the interdental microbiota, which involves regulating the quantity of pathogenic bacteria…
- Conditions
- Microbiota-related Disease, Oral Hygiene, Periodontal Diseases
- Trial name
- HIJA (NCT06848790)
- Testing
- Calibrated interdental brush
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Influenza, Human, Respiratory Tract Infections
A Study to Confirm Efficacy of a Single Dose of Baloxavir Marboxil in the Post-exposure Prophylaxis (PEP) of Influenza Virus Infection in Chinese Participants
The main purpose of the study is to evaluate the efficacy of a single dose of baloxavir marboxil compared with placebo in the PEP of influenza virus infection with respect to symptomatic, laboratory-confirmed influenza in…
- Conditions
- Influenza, Human, Respiratory Tract Infections, Post-exposure Prophylaxis
- Trial name
- Pearlstone (NCT07827599)
- Testing
- Baloxavir marboxil
- Where
- 8 sites in China
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Myopia, Astigmatism
Clinical Study to Evaluate Effectiveness of Digital Refraction
Prospective, comparative, randomized, non-masked clinical study to compare the a digital refraction with LogMAR VA testing utilizing trial lenses, to standard manual refraction using a Phoropter, and LogMAR VA testing, in…
- Trial name
- NCT03502863
- Testing
- Digital refraction, Manual Refraction
- Where
- 3 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Visibly
Hand Injuries and Disorders, Anesthesia, Local
Evaluation of Second Esmarch Application on Intravenous Regional Anesthesia Effectiveness
Intravenous regional anesthesia is a commonly used technique in the outpatient setting for short hand and upper extremity cases, such as carpal tunnel release or trigger finger release.
- Conditions
- Hand Injuries and Disorders, Anesthesia, Local, Upper Extremity Injury
- Trial name
- NCT03702387
- Testing
- standard intravenous regional anesthesia (IVRA) with reapplication of esmach
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Caries
Evaluation of the Anticaries Efficacy of Dentifrice Formulations Using an In-situ Model
The primary objective is to compare the remineralization and demineralization inhibition potential of early subsurface carious lesions in enamel in situ after rinsing with six different aqueous slurries of toothpaste formulations.
- Trial name
- NCT06140758
- Testing
- Oral-B 1450 ppm Fluoride (1.16% sodium monofluorophosphate) Dentifrice, Colgate 1450 ppm Fluoride (1.16% sodium monofluorophosphate)Dentifrice, Toms of Maine 0 ppm Fluoride Dentifrice
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Colorectal Cancer
The Clinical Application of 68Ga Labeled ssDNA Aptamer Sgc8 in Healthy Volunteers and Colorectal Patients
The protein tyrosine kinase-7 (PTK7) is overexpressed in various types of human cancers. As a specific imaging agent of PTK7, 68Ga-Sgc8 was investigated in this study to assess its safety, biodistribution and dosimetric…
- Trial name
- NCT03385148
- Testing
- 68Ga-Sgc8
- Where
- 2 sites in China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
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