Clinical trials: Egg Donors
Infertility, Female, Infertility
Phase II Clinical Trial to Evaluate the Ongoing Pregnancy Rate With OXO-001 in IVF/ICSI With Donor Oocytes.
The main objective of this clinical research trial is to test the efficacy of OXO-001 in a daily oral administration increasing the pregnancy rate in IVF/ICSI by preparing the uterus to receive the embryo.
- Trial name
- OXOART2 (NCT05076032)
- Testing
- OXO-001
- Where
- 28 sites in Czechia, Poland and 1 more
- Volunteers
- 408 people
- Sponsor
- OXOLIFE
Infertility, Donor Oocyte Assisted Reproduction
Fresh Versus Vitrified-Warmed Donor Oocytes: Embryological and Clinical Outcomes
This multicenter retrospective observational study compares embryological and clinical outcomes following treatment with fresh versus vitrified-warmed donor oocytes at Bocian Fertility Clinic centers in Poland.
- Trial name
- FRESH-FROZEN (NCT07904936)
- Testing
- Fresh Donor Oocyte ICSI, Vitrified-Warmed Donor Oocyte ICSI
- Where
- Poland
- Volunteers
- 3,000 people
- Sponsor
- Center for Reproductive Medicine Bocian
Egg Donor Recipient Characteristics
Egg Donor Recipient Characteristics Preferences
To identify the characteristics in an egg donor that are important to a recipient and to see if those characteristics change over time.
- Trial name
- NCT01219491
- Where
- 3 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
Ultrasound Study by Texturization as a Predictor of Pregnancy in Oocyte Donation Programs
This study is focused on analysing the application of ultrasound scanning techniques as new biomarkers in reproductive medicine.
- Trial name
- TEXTUGEST (NCT03507322)
- Testing
- Ultrasound texturization
- Where
- Spain
- Sponsor
- Vida Recoletas Sevilla
Ovarian Stimulation
Impact of Three Different Gonadotrophin Regimes on Egg Donation Program
Exploratory study assessing the effect of three gonadotrophin protocols on Controlled Ovarian Stimulation (COS) parameters and IVF outcome in oocyte donors undergoing GnRH analogue (long protocol).
- Trial name
- NCT00829075
- Testing
- r-FSH, HP-hMG, r-FSH plus HP-hMG
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Recurrent Miscarriage
Effect of Influenza Vaccination on Donor Egg Recipient Outcomes
In this study the investigators propose a randomized controlled trial to evaluate the effect of influenza vaccination on clinical pregnancy rates among women undergoing in vitro fertilization as donor egg recipients.
- Trial name
- DE-FluVac (NCT02946177)
- Testing
- Influenza Vaccine, Sterile Saline
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Infertility
Vaginal Progesterone Versus Progesterone in Oil in Donor Egg Recipient In Vitro Fertilization Cycles Utilizing Vitrified Donor Eggs
The aim of this study is to evaluate both pharmaceutical therapy and advanced treatment techniques for infertile patients requiring in-vitro fertilization utilizing donor eggs.
- Trial name
- NCT01465373
- Testing
- Endometrin, Progesterone in Oil
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fertility Centers of Illinois
EMBRYO IMPLANTATION
Endometrial Scratch Effect on Pregnancy Rates in Patients Undergoing Egg-donation IVF
Clinical trial about the effect of endometrial scratch on pregnancy rates in patients undergoing a treatment with in-vitro fertilization with donor eggs, when doing the endometrial biopsy during the cycle prior to the embryo…
- Trial name
- NCT03108157
- Testing
- Endometrial scratch
- Where
- Spain
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Procreatec
Vitrification, Egg Donor
Validation of Donor Oocytes Semi-automated Vitrification
Oocyte vitrification is an effective method of freezing which has been authorized in France since 2011. The arrival of this technique has led to real improvements in the survival rate of oocytes after warming compared to that…
- Conditions
- Vitrification, Egg Donor, Fertility, Assisted Reproductive Technology
- Trial name
- GAVIDO (NCT06238570)
- Testing
- Gavi, Merck® (automated vitrification instrument), Vitrolife system
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anonymous Donors
Study of Ovum Donors After Donation
To explore the attitudes and reactions of ovum donors prospectively after ovum donation and to follow their medical histories.
- Trial name
- NCT01219374
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Implantation, Embryo
A Novel Approach to Endometrial Preparation in Recipients of Donor Eggs
This study compares two different methods to prepare the uterine lining of recipients for implantation in cycles using donor eggs. The study method requires less time than the standard method.
- Trial name
- NCT01424618
- Testing
- Leuprolide, Ganirelix
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kelly, Maureen, M.D.
Stimulation in the Ovary
A Comparative Study of Two Patterns of Controlled Ovarian Hyperstimulation in Mid Follicular Phase or Early Luteal Phase for Egg Donors
The purpose of this study is to determine the efficacy and safety of two new patterns of controlled ovarian hyperstimulation (defined as total number of picked up eggs).
- Trial name
- NCT01385332
- Testing
- Early luteal phase, Late follicular phase -COH-
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve
Vitamin D Influence on Oocyte Donation
Objective: To investigate the correlation between total and bioavailable serum 25-OH vitamin D, ovarian reserve and ovarian response to controlled stimulation in egg donors.
- Conditions
- Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve, Hormonal Requirement, Reproductive Disorder
- Trial name
- NCT02341365
- Testing
- vitamin D,AMH, AFC, reproductive outcome egg recipients
- Volunteers
- 269 people
- Sponsor
- IVI Madrid
Infertility, Female
Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix
The main purpose of this clinical research study is to investigate if degarelix can synchronise the growth of the egg sacs in the ovaries and if degarelix has any effect on the lining of the womb.
- Trial name
- NCT00434122
- Testing
- Degarelix mid-luteal, 2.5 mg
- Where
- 4 sites in Belgium, Czechia and 1 more
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Infertility, Female, Oocyte Maturation
Second Phase of the Pilot Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women
In vitro maturation (IVM) is a technique for obtaining potentially fertilizable oocytes from immature oocytes. An oocyte must be mature both nuclearly and cytoplasmically in order to be competent in the reproductive process.
- Trial name
- MIVODON-II (NCT06103383)
- Testing
- Controlled ovarian stimuation, Oocyte pick up, Oocyte in vitro maturation
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Hysteroscopy, Oocyte Recipients
Hysteroscopy With Fundus Uterus Scratching Incision VS Office Hysteroscopy Before ET With Donor Eggs
A prospective randomised control trial of the impact of the fundus edometrial incision during hysteroscopy in oocyte recipients.
- Trial name
- NCT04580056
- Testing
- Uterine fundus endometrial incision during hysteroscopy
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Infertility
Closed Vitrification of Oocytes
This study is aimed to evaluate the use of a closed device for storage of vitrified oocytes.
- Trial name
- NCT01745536
- Testing
- Oocytes are vitrified/stored using a closed device, Oocytes are vitrified/stored using an open device
- Where
- 2 sites in Spain
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility
Clinical Pregnancies After Cryopreservation of Donor Oocytes With an Open or Closed Device
This randomized pilot study will assess if there is a difference in clinical pregnancies using donor oocytes cryopreserved in either a closed or a semi-closed vitrification device.
- Trial name
- NCT02940106
- Testing
- Cryotop device, CBSvit device
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
INFERTILITY, Fertility Preservation
Evolutive Potential of Embryos Obtained From Oocytes After Luteal Phase Ovarian Stimulation
The purpose of this study is to evaluate the clinical pregnancy rate per embryo transfer in oocytes recipients obtained after ovarian stimulation during the luteal phase of oocytes donors .
- Conditions
- INFERTILITY, Fertility Preservation, Ovulation Induction, Vitrification
- Trial name
- NCT01645241
- Testing
- gonadotropins plus GnRH antagonists, ganirelix
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Female Infertility
Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women
In vitro maturation (IVM) is a technique for obtaining potentially fertilizable oocytes from immature oocytes. An oocyte must be mature both nuclearly and cytoplasmically in order to be competent in the reproductive process.
- Trial name
- IVM (NCT03998553)
- Testing
- IN VITRO MATURATION AND OOCYTE ACTIVATION
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA