Clinical trials: Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Hypermobile EDS (hEDS), Hypermobility Syndrome
Dyspnea in Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorder
Individuals with hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD) often experience dyspnea. Inspiratory Muscle Training (IMT) has been shown to improve dyspnea and respiratory muscle function…
- Trial name
- NCT04972565
- Testing
- Usual Care plus Inspiratory Muscle Training (IMT)
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University Health Network, Toronto
Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome
Hamstring Strengthening in Hypermobile Conditions
The goal of this clinical trial is to determine how strengthening the hamstring muscles affects the knee joint in people living with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).
- Conditions
- Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder, Hypermobility Type Ehlers-Danlos Syndrome
- Trial name
- NCT07626957
- Testing
- Progressive resistance exercise with an emphasis on eccentric hamstring loading.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Hypermobile Ehlers-Danlos Syndrome
TMD-specific Physiotherapy in hEDS Patients Individuals With Hypermobile Ehlers-Danlos Syndrome
The aim of this study is to analyze the effects of strictly defined physiotherapy in patients temporomandibular dysfunction (TMD) and hypermobile Ehlers-Danlos Syndrome (hEDS).
- Trial name
- NCT05757960
- Testing
- Physiotherapy
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital Muenster
Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
3D Printed Orthosis for Wrist Instability for Ehlers-Danlos Syndrome Patient
This study will determine if using 3D scanning and 3D printing technology to create an orthosis to improve the quality of life for people with Ehlers Danlos Syndrome (EDS) compared to existing prefabricated orthoses.
- Trial name
- NCT07565636
- Testing
- 3D scanned and 3D printed wrist hand orthosis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- ELewis
Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS)
STABLE Pilates for Hypermobility
This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.
- Conditions
- Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS), Hypermobile Spectrum Disorder
- Trial name
- STABLE (NCT07464093)
- Testing
- Pilates, Education
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS)
Regenerative Medicine for Joint Hypermobility and Instability
This clinical trial is designed to evaluate whether a stepwise injection-based treatment approach can reduce pain and improve function in adults with joint hypermobility, connective tissue laxity, and joint instability.
- Conditions
- Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS), Joint Hypermobility, Joint Instability
- Trial name
- NCT07688096
- Testing
- Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational)
- Volunteers
- 100 people
- Sponsor
- Manhattan Pain Medicine, PLLC
Hypermobile Ehlers-Danlos Syndrome, Irritable Bowel Syndrome
Comprehensive Assessment of Nutrition and Dietary Intervention in Hypermobile Ehlers Danlos Syndrome
This study involves a comprehensive nutritional assessment of hEDS participants who have functional gastrointestinal disorders and dietary intervention to broaden their food choices and nutritional intake.
- Conditions
- Hypermobile Ehlers-Danlos Syndrome, Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
- Trial name
- CANDI-hEDS2 (NCT05148039)
- Testing
- Dietician advice
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Queen Mary University of London
Joint Hypermobility Syndrome, Hypermobile Ehlers-Danlos Syndrome
Central Sensitization and Physical Activity in Adolescents With HSD/hEDS
Hypermobility Spectrum Disorder and hypermobile Ehlers-Danlos Syndrome (HSD/hEDS) is under-recognized and poorly understood and its management is therefore not clear.
- Trial name
- NCT05633225
- Testing
- Submax exercise test on a bicycle ergometer
- Where
- 2 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Hypermobile EDS (hEDS)
Out of State - tAN hEDS
Hypermobile EDS and hypermobile spectrum disorder (collectively referred to as hEDS) are estimated to affect 1 in 500 individuals worldwide.
- Trial name
- NCT06548594
- Testing
- Transcutaneous Auricular Neurostimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Ehlers-Danlos Syndrome, EDS
Characterization of Bleeding Disorders in EDS
Ehlers-Danlos Syndrome (EDS) is a disease that weakens the connective tissues (i.e. tendons and ligaments) in the human body. EDS can make the joints loose and alter skin and wound healing.
- Conditions
- Ehlers-Danlos Syndrome, EDS, Classical Ehlers-Danlos Syndrome, Classical EDS (cEDS)
- Trial name
- NCT05434728
- Testing
- 20 ml venous blood collection
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University Health Network, Toronto
Hypermobile Ehlers-Danlos Syndrome, Hypermobility Syndrome
Patient-based Care Versus Standard Care for Patients With hEDS/HSD and Multidirectional Shoulder Instability
For hEDS or HSD patients with MDI, a multidisciplinary treatment approach is suggested. As follows, physiotherapy plays a key role in this integrative management.
- Conditions
- Hypermobile Ehlers-Danlos Syndrome, Hypermobility Syndrome, Multidirectional Subluxation of Shoulder
- Trial name
- NCT04666896
- Testing
- Tailored home-based exercise therapy, Standard home-based exercise therapy
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- University Ghent
Ehlers-Danlos Syndrome, Hypermobile EDS (hEDS)
Integrative Medicine for Hypermobility Spectrum Disorder and Ehlers-Danlos Syndromes (IMforHSDandEDS)
A feasibility study of an integrative medicine program among patients with Hypermobility Spectrum Disorder (HSD) or Ehlers-Danlos syndromes (EDS)
- Conditions
- Ehlers-Danlos Syndrome, Hypermobile EDS (hEDS), Hypermobility Syndrome, EDS
- Trial name
- NCT04734041
- Testing
- Anti-inflammatory (Mediterranean-style) diet, Behavioral and psychosocial support
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National University of Natural Medicine
Ehlers-Danlos Syndrome, Classical Ehlers-Danlos Syndrome
Ultrastructural Collagen Markers in Ehlers Danlos Syndromes
Establishing the diagnosis of Ehlers Danlos Syndromes (EDS)/generalized hypermobility spectrum disorders (G-HSD) is often problematic for patients.
- Conditions
- Ehlers-Danlos Syndrome, Classical Ehlers-Danlos Syndrome, Hypermobile EDS (hEDS)
- Trial name
- NCT05429996
- Testing
- Skin Biopsy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
Validity of Somatosensori Remediation for Postural Control in the Treatment of Ehlers-Danlos Syndrome Hypermobility Type (hEDS)
In the absence of a medical consensus, the current management of Ehlers-Danlos Syndrome hypermobility type (hEDS) remains very speculative That's why investigators want in this study to demonstrate the beneficial contribution of…
- Trial name
- VITALISED (NCT04020107)
- Testing
- Compressive garment and Somatosensori Remediation
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen