Clinical trials: Elder
Mental Health
Mentalizing Imagery Therapy for Caregivers to Address Risk of Elder Mistreatment
The purpose of this study is to establish the clinical efficacy of Mentalizing Imagery Therapy (MIT) for Alzheimer's Disease and Related Disorders (ADRD) family caregivers in terms of mentalizing and elder mistreatment (EM) risk…
- Trial name
- (MIT-CARE) (NCT07648238)
- Testing
- Mentalizing Imagery Therapy, Mindfulness Exercises.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Cancer, Stage III Breast Cancer
TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
This research is being done to assess whether an exercise intervention with protein intake support vs a health education and support program will make it easier for women age 65 or older who are receiving chemotherapy for breast…
- Conditions
- Breast Cancer, Stage III Breast Cancer, Breast Cancer Female, Stage I Breast Cancer
- Trial name
- THRIVE-65 (NCT05535192)
- Testing
- THRIVE, Health Education Support Program
- Where
- 4 sites in United States
- Volunteers
- 270 people
- Sponsor
- Dana-Farber Cancer Institute
Adverse Reaction to Drug, Health Behavior
Personal Health Records and Elder Medication Use Quality
Purpose: To examine the impact of a personal health record (PHR) on medication use safety among older adults. Background: Online PHRs have potential as tools to manage health information.
- Conditions
- Adverse Reaction to Drug, Health Behavior, Medication Adherence, Physician-Patient Relations
- Trial name
- NCT02012712
- Testing
- Personal Health Record (PHR)
- Where
- United States
- Volunteers
- 1,163 people
- Sponsor
- University of Iowa
Diabetes Mellitus, Microbiome
Supplementation of Inulin + L. Acidophilus in Elders With T2DM
This study investigates the effects of a symbotic supplement (Inulin + Lactobacillus acidophilus) on cognitive impairment in older adults with type 2 diabetes mellitus (T2DM).
- Conditions
- Diabetes Mellitus, Microbiome, Cognition Disorders
- Trial name
- NCT06830824
- Testing
- Lactobacillus acidophilus
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Anahuac University
Indigenous Older Adult Health and Wellbeing
Elders Moving Together: A Pilot Study
This pilot study evaluates the feasibility and acceptability of implementing the Saskatchewan Forever in Motion (FIM) group exercise program in a First Nations community in northwestern Saskatchewan.
- Trial name
- NCT07561008
- Testing
- Exercise Program
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Saskatchewan
Post-operative Cognitive Decline, Post-operative Delirium
Cardiac Surgery Neuroprotection Study in Elders
The goal of this study is to determine the potential ability of intranasal insulin to prevent post-operative cognitive decline and post-operative delirium in an elderly cardiac surgery population.
- Trial name
- CNS-Elders (NCT01561378)
- Testing
- Aspart insulin, Normal saline, Intranasal mucosal atomizer device
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Albert Einstein College of Medicine
Frail Older Adutls
Systems Addressing Frail Elders (SAFE) Care Implementation
Systems Addressing Frail Elders (SAFE) Care is a nurse-led interprofessional team model to rapidly identify and provide safe and effective inpatient care to high risk older adults and help support their successful transition back…
- Trial name
- SAFE (NCT02854826)
- Testing
- SAFE Care model of care
- Volunteers
- 330 people
- Sponsor
- Cedars-Sinai Medical Center
Frail Elderly
Project ABLE:Advancing Better Living for Elders
The specific aims of the study are to: 1) test the effectiveness of a home-bases intervention to improve home safety, fall efficacy and functional performance; 2) determine if the use of environmental strategies results in…
- Trial name
- NCT00249925
- Testing
- Home-Based Intervention, Multi-component home-based intervention
- Where
- United States
- Volunteers
- 319 people
- Sponsor
- Thomas Jefferson University
Visual Acuity
Ophthalmologic Examinations After Infusion of ZK200775
ZK 200775 is an antagonist at the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor and had earned attention a possible neuroprotective agent in cerebral ischemia.
- Trial name
- NCT00999284
- Testing
- ZK200775, Sodium Chloride
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Sleep Disorder
Sleep Hygiene Intervention on Sleep Quality Improvement in Elders With Parkinson's Disease
Sleep disorders (SDs) are one of the most frequent non-motor symptoms of Parkinson's disease (PD), usually increasing in frequency over the course of the disease and disability progression.
- Trial name
- NCT06937632
- Testing
- sleep hygiene intervention
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Alexandria University
Hearing Loss
Aging, Cognition, and Hearing Evaluation in Elders Study
The investigators will conduct a small pilot study that will randomize ~ 40 70-84 year-old adults with hearing loss to best-practices hearing rehabilitative treatment (hearing assessment, counseling, fitting of amplification…
- Trial name
- ACHIEVE-P (NCT02412254)
- Testing
- Best practices hearing rehabilitative treatment, Successful aging intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cognitive Impairment, Mild Cognitive Impairment
Evaluation of Cognitive and Physical Training on MCI Elders
This study examines the impact of combining cognitive and physical training, recognizing that daily living often requires individuals to perform multiple tasks simultaneously.
- Trial name
- NCT06572878
- Testing
- Cognitive training, Physical training, Combined cognitive and physical training
- Volunteers
- 144 people
- Sponsor
- Taipei Medical University
Accidental Falls
The Feasibility of Nintendo RingFit to Improve Balance and Muscle Strength of Elders
Background Existing findings have suggested that exergaming (i.e., exercise that requires people to move their body to play, providing an active gaming experience while serving as a form of physical activity), may have a…
- Trial name
- NCT05949359
- Testing
- Nintendo RingFit-augmented exercise program
- Where
- Hong Kong
- Volunteers
- 43 people
- Sponsor
- The Hong Kong Polytechnic University
High Intensity Exercise, Normal Cognition
CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)
The overall goal of the CYCLE-AD trial is to determine the role of long-term, high intensity exercise in slowing or delaying the onset of cognitive and AD-related brain changes in e4 carriers.
- Conditions
- High Intensity Exercise, Normal Cognition, Exercise Intervention
- Trial name
- CYCLE-AD (NCT04748861)
- Testing
- Indoor Cycling (IC)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Depression, Anxiety
Positive Minds Strong Bodies Implementation
This study aims to address treatment and service disparities and prevent disability among racial/ethnic and linguistic minority elders.
- Conditions
- Depression, Anxiety, Physical Disability
- Trial name
- PMSB-E (NCT04545593)
- Testing
- Positive Minds Strong Bodies Enhanced, Enhanced Usual Care
- Where
- United States
- Volunteers
- 427 people
- Sponsor
- Massachusetts General Hospital
Sedentary Lifestyle, Risk of Disability
The LIFE Study - Lifestyle Interventions and Independence for Elders
Based upon promising results from a pilot study among 424 sedentary older adults who were randomized to a physical activity intervention or a successful aging health education intervention, a Phase 3 multi-center randomized…
- Conditions
- Sedentary Lifestyle, Risk of Disability, Aging
- Trial name
- LIFE (NCT01072500)
- Testing
- Physical Activity, Successful Aging
- Where
- 8 sites in United States
- Volunteers
- 1,635 people
- Sponsor
- University of Florida
Advance Care Planning
I Kua na'u Advance Care Planning for Native Hawaiian Elders
Communication surrounding serious illness decision making is formalized in Advance Care Planning (ACP), a process involving verbal or written information designed to inform patients of possible medical options including…
- Trial name
- NCT04771208
- Testing
- I kua na'u "Let Me Carry Out Your Last Wishes"
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Stress
Education Program for Family Caregivers
The purpose of this evaluation was to determine the effectiveness of an educational program designed to assist family caregivers to learn the knowledge and skills to take better care of their frail elder relatives and themselves.
- Trial name
- NCT00764647
- Testing
- Education program for family caregivers of frail elders
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Depression, Anxiety, Fatigue
Feasibility Study of a Modified Yoga Program for Elders
The purpose of this study is to determine whether a modified yoga program helps improve pain and function in elders age 65 years or older living in an assisted living community.
- Conditions
- Depression, Anxiety, Fatigue, Pain, Chronic, Sleep
- Trial name
- NCT04343625
- Testing
- Modified yoga class
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Functional Fitness, Health Promotion
12-week Pilates Program on Community-dwelling Middle-aged Women
The purpose of this study was to investigate the effects of a Pilates exercise intervention program on functional physical fitness in community-dwelling middle-aged women.
- Conditions
- Functional Fitness, Health Promotion, Exercise, Frail Elderly Syndrome
- Trial name
- NCT05333484
- Testing
- Programed Pilates
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences