Clinical trials: Elderly
Meningococcal ACWY Disease
A Study To Evaluate A Booster Dose Of Menacwy-tt Vaccine Administered 10 Years After Healthy Subjects Aged 11-17 Years Received Either Menacwy-tt Vaccine (Nimenrix(Registered)) Or Mencevax Acwy(Registered).
This study will evaluate the immunogenicity, reactogenicity and safety of a booster dose of MenACWY-TT vaccine administered 10 years after healthy subjects aged 11-17 years received either MenACWY-TT vaccine (Nimenrix) or…
- Trial name
- NCT03189745
- Testing
- MenACWY-TT
- Where
- Philippines
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Pfizer
Autism Spectrum Disorder (ASD)
Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children Aged From 2 to Less Than 7 Years Old With Autism Spectrum Disorder.
The purpose of this study was to evaluate the efficacity and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.
- Trial name
- NCT03715153
- Testing
- BUMETANIDE (S95008) for week 0 - 26, Open-Label BUMETANIDE (S95008) for weeks 26 - 52
- Where
- 50 sites in United States, Australia and 10 more
- Volunteers
- 211 people
- Sponsor
- Institut de Recherches Internationales Servier
Influenza
Second Extension Study to Evaluate Safety and Tolerability of Influenza Vaccines in Adults and Elderly, and to Evaluate Immunogenicity and Concomitant Vaccination With Pneumococcal Vaccine in a Subgroup
The study primarily aims to evaluate immunogenicity and safety of influenza vaccines (cell culture derived seasonal trivalent influenza vaccine (cTIV) or influenza virus vaccine (egg-derived seasonal trivalent, thiomersal free…
- Trial name
- NCT00579345
- Testing
- Cell culture derived seasonal trivalent influenza vaccine (cTIV), Influenza virus vaccine (egg-derived seasonal trivalent, thiomersal free; eTIV_a)., cTIV or eTIV_a
- Where
- 5 sites in Poland
- Volunteers
- 1,522 people, healthy volunteers welcome
- Sponsor
- Novartis
Deep Vein Thrombosis
Innohep® in Elderly Patients With Impaired Renal Function Treated for Acute Deep Vein Thrombosis
The objective of the study is to compare the safety of innohep® and Unfractionated Heparin (UFH) in terms of clinically relevant bleedings in elderly patients with impaired renal function for initial treatment of acute Deep…
- Trial name
- NCT00277394
- Testing
- innohep®, Heparin
- Where
- 9 sites in Bulgaria, Croatia and 7 more
- Volunteers
- 541 people
- Sponsor
- LEO Pharma
Obesity, Sedentary Lifestyle
I-STAND R21: Reducing Sedentary Time in Older Adults
The investigators are doing a study to learn how to support patients aged 60+ in taking more breaks from sitting and reducing total sitting time.
- Trial name
- NCT02692560
- Testing
- I-STAND, Healthy Living
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kaiser Permanente
Mobility Limitation, Aging
HOMEStudy: Development of a Home-based Self-delivered Prehabilitation Intervention to Proactively Reduce Fall Risk in Older Adults
Older adults often have difficulty performing complex walking tasks leading to increased fall incidence and subsequent injury. Even in the best clinical settings, it may not be possible for patients or clinicians to dedicate the…
- Trial name
- NCT05583578
- Testing
- Home-based mobility testing and active tDCS
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Florida
Accidental Falls
Prevention of Falls in the Elderly Population
An educational intervention will be utilized to improve care following guidelines for treating individuals at risk of falling. A survey will be administered to providers pre and post education.
- Trial name
- NCT03614897
- Testing
- Education
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- The Guthrie Clinic
Chronic Low Back Pain, Hip Ostearthritis
Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
Back pain is a huge problem for millions of Americans, including nearly 11 million Veterans. Our older Veterans suffer the most. Citizens spend billions of dollars, yet consistently get poor results.
- Conditions
- Chronic Low Back Pain, Hip Ostearthritis, Myofascial Pain Syndrome, Fibromyalgia
- Trial name
- NCT02697435
- Testing
- Patient-Centered Care, Imaging-Directed Care
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Influenza
A Study of Immunogenicity and Safety of GSK Biologicals' Influenza Vaccine FLU-Q-QIV in Adults Aged 18 Years and Older
The purpose of this study is to evaluate the immunogenicity and the safety of GlaxoSmithKline (GSK) Biologicals' investigational quadrivalent split virion influenza vaccine FLU-Q-QIV in adults 18 years of age and older.
- Trial name
- NCT01440387
- Testing
- FLULAVAL® QUADRIVALENT
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Quality of Life, End Stage Renal Disease
Improved Selection of Elderly (> 65 Years) for Kidney Transplantation
Kidney transplantation has been shown to provide improved survival even in patients older than 70 years of age. The purpose of the study is to determine whether kidney transplantation provides any improvement of health related…
- Conditions
- Quality of Life, End Stage Renal Disease, End Stage Renal Failure on Dialysis
- Trial name
- QUESTION65 (NCT01760733)
- Where
- Norway
- Volunteers
- 289 people
- Sponsor
- Sykehuset Telemark
Influenza
Study of a Single Dose or Two Doses of a Quadrivalent Influenza Vaccine in Subjects Aged 6 Months or Older in India
The aim of the study was to generate immunogenicity and safety data in the whole population to support registration of the Quadrivalent Influenza Vaccine (QIV) in India: Primary objective: To describe in each age group the immune…
- Trial name
- NCT02451358
- Testing
- Quadrivalent Inactivated Influenza Vaccine (2016-2017 NH formulation), No Preservative, Quadrivalent Inactivated Influenza Vaccine (2016 SH formulation), No Preservative, Quadrivalent Inactivated Influenza Vaccine (2015-2016 NH formulation), No Preservative
- Where
- 8 sites in India
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Loneliness, Quality of Life
The Helping Older People Engage Project: Improving Social Well-Being in Later Life
Older adults who feel lonely carry increased risk for reduced quality of life, morbidity, and mortality. Volunteering is a promising intervention for reducing loneliness in later life.
- Trial name
- HOPE (NCT03343483)
- Testing
- Volunteering, Life Review
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- University of Rochester
Substance Use, Parenting
Feasibility Study of a Web-based Program to Help Parents of Middle School Students Effectively Communicate With Their Children About Substance Use
The goal of this study is to test the feasibility of a web-based program for parents of middle school aged students. 286 parents and their child in 6th, 7th, or 8th grade will be asked to each complete two online questionnaires…
- Conditions
- Substance Use, Parenting, Communication
- Trial name
- NCT05900115
- Testing
- Media Ready Parent, Active Control Program
- Where
- United States
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Innovation Research & Training
Cardiovascular Diseases in Old Age
Yoga in Older Cardiac Patients
The goal of this clinical trial is to compare, at 3 months, the effects of a yoga intervention on physical health, including balance, muscle strength, physical activity levels, cardiac autonomic function, and physical…
- Trial name
- NCT06235658
- Testing
- Gentle Yoga
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Geunyeong Cha
Chronic Pain
Tracking Physical Activity for Chronic Pain Management Among Older Adults in Detroit
Wearable, commercially-available physical activity monitors are being increasingly incorporated into chronic pain self-management interventions as a tool to help patients set goals and to tailor intervention content based on…
- Trial name
- NCT03285958
- Testing
- STEPS Intervention
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Michigan
Crohn's Disease
Safety Study of Entocort for Children With Crohn's Disease
A Safety Study using Entocort EC for children with mild to moderate Crohn's Disease
- Trial name
- NCT01444092
- Testing
- Entocort
- Where
- 24 sites in United States, Canada and 3 more
- Volunteers
- 123 people
- Sponsor
- Padagis LLC
Emotional Distress, Anxiety
Five Session Unified Protocol for Older Adults With Emotional Distress and Reduced Mobility
Research suggests older adults report wide-ranging emotional distress (e.g., symptoms of anxiety, depression) that negatively impacts their physical and mental health and is associated with a reduction in daily activity.
- Conditions
- Emotional Distress, Anxiety, Depression
- Trial name
- NCT04837521
- Testing
- Unified Protocol
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Major Depressive Disorder
Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study)
Late-life depression is characterized by both affective (mood) symptoms and cognitive deficits. There is currently no intervention that may provide consistent benefits to both mood and cognitive performance.
- Trial name
- NCT02816138
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Vanderbilt University Medical Center
Infections, Meningococcal
Primary Study to Demonstrate Non-inferiority and Immunogenicity of GSK Biologicals' Meningococcal Vaccine 134612
This study will demonstrate the non-inferiority of GSK Biologicals' meningococcal vaccine 134612 when given in an experimental co-administration versus vaccine 134612 alone and versus the experimental co-administration alone in…
- Trial name
- NCT00465816
- Testing
- Nimenrix (Meningococcal vaccine 134612), Twinrix
- Where
- 6 sites in Denmark, Sweden
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sarcopenia
A Study of Muscle Strength Maintenance in Older Adults
This research study is being done to see whether losartan can prevent the decrease in strength associated with aging. Muscle loss is associated with aging and has multiple symptoms such as weakness, slowness, and fatigue…
- Trial name
- NCT01989793
- Testing
- Losartan
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
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