Clinical trials: Elderly Adults
Diabetes Mellitus, Aging
Lifestyle Intervention for Senior Diabetics
Older people with diabetes will be assigned to the 1-year lifestyle program or no lifestyle program while continuing usual treatment for diabetes.
- Conditions
- Diabetes Mellitus, Aging, Overweight
- Trial name
- LISD (NCT02348801)
- Testing
- Weight loss and Exercise, Healthy lifestyle
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Respiratory Syncytial Virus Infection, Respiratory Syncytial Virus Infections
Genotype and Disease Burden of RSV in Older Vietnamese Adults (RSV: Respiratory Syncytial Virus )
This observational, prospective, multicenter study aims to estimate the proportion of RSV infection in adults aged 60 years and older hospitalized due to acute respiratory infections or exacerbation of cardiopulmonary disease.
- Trial name
- RSV-VN-Elderly (NCT07239583)
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- Tam Anh Research Institute
Bariatric Surgery Candidate, Bone Loss
Weight Loss With Risedronate for Bone Health
This is a pilot project to determine the feasibility of recruiting, enrolling, treating, and following 24 older sleeve gastrectomy patients into a randomized controlled trial (RCT) examining the efficacy of bisphosphonate use…
- Conditions
- Bariatric Surgery Candidate, Bone Loss, Weight Loss
- Trial name
- WERISE (NCT03411902)
- Testing
- Risedronate Sodium 150 MG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Chronic Pain
Effects of Tai Chi on Multisite Pain and Brain Functions in Older Adults
The main purpose of this randomized controlled trial was to assess the feasibility and acceptability of a 12-week Tai Chi program for community-dwelling older adults with chronic multisite pain and a history of falling.
- Trial name
- NCT03086772
- Testing
- Tai Chi, Light Exercise
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Massachusetts, Boston
Stress, Psychological
Improving Well-Being for Older Adult Family Dementia Caregivers
This study will examine the effects of the Mindfulness-Based Stress Reduction (MBSR) program and the Living Well program, compared to a control group, to see if the programs might be associated with better immune function…
- Trial name
- NCT03881631
- Testing
- Mindfulness Based Stress Reduction Program, Living Well Program
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Obesity (Disorder), Obesity
Effect of Vitamin D on Body Composition and Functionality of Older Adults
Older adults with obesity often experience a gradual loss of muscle mass and muscle strength, a condition sometimes described as sarcopenic obesity.
- Conditions
- Obesity (Disorder), Obesity, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT07275177
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 29 people
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes
This phase I trial studies the side effects and best dose of iodine I 131 monoclonal antibody BC8 when given together with fludarabine phosphate and low-dose total-body irradiation followed by donor stem cell transplant and…
- Conditions
- Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)
- Trial name
- NCT00008177
- Testing
- iodine I 131 monoclonal antibody BC8, total-body irradiation, allogeneic hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Fred Hutchinson Cancer Center
Functional Ability, Cognitive Decline
Caregiver Training: Evidence of Its Effectiveness for Cognitive and Functional Improvement in Older Adults
Due to demographic changes that have resulted in an aging population, the role of caregiver of an older adult has become very important in recent years.
- Conditions
- Functional Ability, Cognitive Decline, Older Adults, Healthy Aging
- Trial name
- NCT04490070
- Testing
- Cognitive Stimulation
- Where
- 10 sites in Spain
- Volunteers
- 160 people
- Sponsor
- Universidad de Granada
Neurocognitive Disorders
VItamin K Inhibition and NeurocoGnition (VIKING)
The primary objective of this study is to determine whether patients usually taking Vitamin K Antagonists (VKAs) exhibit a poorer global cognitive performance than control patients (matched on age, gender and indication for…
- Trial name
- VIKING (NCT03276377)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Generalized Anxiety Disorder
Physical Exercise Augmented CBT for GAD
Generalised anxiety disorder (GAD) is a severe and debilitating anxiety disorder that is highly prevalent among older adults. Anxiety and GAD is a well-documented risk factor for the development of other severe conditions such as…
- Trial name
- PEXACOG (NCT02690441)
- Testing
- Cognitive Behavioural Therapy, Physical Exercise
- Where
- Norway
- Volunteers
- 53 people
- Sponsor
- Solli Distriktspsykiatriske Senter
Major Depression
A Randomized Control Trial of Enhanced Cognitive Behavioural Group Therapy for Older Adults with Depression: Efficacy Across Older Age-Groups
This study is on a type of psychotherapy to treat depression in older adults called Cognitive Behavioural Therapy (CBT-OA). CBT is based on the idea that changing thoughts and behaviours can improve mood.
- Trial name
- NCT06894641
- Testing
- Cognitive Behavior Therapy for Older Adults (CBT-OA)
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Falls, Balance
Toileting at Night in Older Adults: Light to Maximize Balance, Minimize Insomnia
To examine the change in balance that occurs in older individuals when exposed to different colored lights at night.
- Conditions
- Falls, Balance, Insomnia, Aging
- Trial name
- NCT01350505
- Testing
- White light exposure, Dim white light exposure, Very dim white light exposure
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Long COVID, COVID-19 Pandemic
Long COVID and Its Associations With Health Outcomes in Older Adults
The Peking University Health Cohort in Anning, Yunnan (PKUHC-AN) is a prospective cohort study carried out in Anning, Yunnan. The primary aim of this study is to investigate the impact of COVID-19 on older adults' health, and to…
- Conditions
- Long COVID, COVID-19 Pandemic, Elderly Infection, Vaccine Reaction
- Trial name
- NCT05825651
- Testing
- no interventions
- Where
- China
- Volunteers
- 11,527 people, healthy volunteers welcome
- Sponsor
- Peking University
Iron Deficiency Anemia
Efficacious Iron for Iron Deficiency Anemia in Adults Aged ≥18 Years
Iron deficiency anemia (IDA) is a widespread condition affecting many people globally. Despite the many cases of IDA, there are few studies that compare the effectiveness of different types of iron supplements with a greater…
- Trial name
- NCT06303531
- Testing
- Ferrous Fumarate, Polysaccharide Iron, Ferrous Ascorbate
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- Dr. Anil K. Gupta Medicine Professional Corporation
Healthy
A Study of the Safety of PAZ-417 in Healthy Elderly Adults
This is study to determine the safety of PAZ-417 in healthy adults over 65.
- Trial name
- NCT00663065
- Testing
- PAZ-417
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Frailty, Frail Elderly Syndrome
Education for Prevention and Treatment of Frailty
Frailty is a condition with a high prevalence in older adults, leading to higher vulnerability and increasing the risk of adverse health outcomes and disabilities.
- Trial name
- FRAGSALUD (NCT05610605)
- Testing
- Health intervention programme: FRAGSALUD
- Where
- Spain
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Aging
Using TMS to Increase Executive Function in Older Adults
Cognitive decline and dementia have become important public health issues in our time as medical science has increased lifespan and our society becomes progressively older.
- Trial name
- WMTMS (NCT02767323)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Duke University
Depression, Depression in Old Age
Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults
The investigators developed EM/PROTECT, a behavioral intervention for depressed EM (elderly mistreatment) victims, to work in synergy with EM mistreatment resolution services that provide safety planning, support services, and…
- Conditions
- Depression, Depression in Old Age, Elder Abuse, Anxiety
- Trial name
- NCT04258579
- Testing
- PROTECT with Technology Augmentation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Device Ineffective
Wearable Monitoring Device in Daily Lives of Community-dwelling Older Adults
The aim is to implement an intervention program to promote the continued use of Wearable Monitoring Devices among older adults through a peer support approach facilitating the incorporation of Wearable Monitoring Devices in daily…
- Trial name
- NCT05269303
- Testing
- Live With Wearable Monitoring Device program
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Diabetes Mellitus, Type 2, Influenza
Information-Based Interventions for Influenza Vaccination Among Older Adults With Diabetes in Yangzhou, China
Influenza can cause serious illness in older adults, particularly those with diabetes. Although influenza vaccination is an important preventive measure, vaccination uptake among older adults in China remains low.
- Trial name
- NCT07901673
- Testing
- Standard Information Intervention, Gain-Framed Information Intervention, Loss-Framed Information Intervention
- Where
- 4 sites in China
- Volunteers
- 759 people
- Sponsor
- Southeast University, China