Clinical trials: Elderly Cancer Patients
Hematopoietic/Lymphoid Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Quality of Life in Caregivers of Hospitalized Older Patients With Cancer
This clinical trial studies quality of life in caregivers of hospitalized older patients with cancer.
- Trial name
- NCT01866969
- Testing
- questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Diffuse Large B Cell Lymphoma
The Efficacy and Safety of ZR2 Versus R-CHOP-like Regimen for Elderly Patients With Newly Diagnosed Diffuse Large B Cell Lymphoma.
This is a prospective, single-center, open-label clinical study designed to evaluate the efficacy and safety of the Zanubrutinib, Lenalidomide and Rituximab (ZR2) versus rituximab combined with CHOP or CDOP (R-CHOP or R-CDOP) in…
- Trial name
- NCT05428670
- Testing
- Zanubrutinib+Rituximab+Lenalidomide, RCHOP/RCDOP
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Colo-rectal Cancer, Shared Decision Making
Shared Decision-Making for Colorectal Cancer Screening in High-Risk First-Degree Relatives Aged 40-49
The primary objective of this study was to evaluate the impact of a constructed shared decision (SDM) intervention (offering an option between colonoscopy and immunochemical collapsible occult blood testing (fecal immunochemical…
- Conditions
- Colo-rectal Cancer, Shared Decision Making, Patient Decision Aid
- Trial name
- NCT07503847
- Testing
- Colonoscopy, Shared Decision-Making
- Where
- Taiwan
- Volunteers
- 2,286 people
- Sponsor
- National Taiwan University Hospital
Hepatocellular Carcinoma
Effect of Nutritional Indices on the Prognosis of HCC Patients
Primary liver cancer has recently ranked among the leading causes of cancer death, with hepatocellular carcinoma (HCC) accounting for 75%-85% of these cases.
- Trial name
- NCT05635279
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Juan Kang
Carcinoma, Non-small Cell Lung
Single Agent Versus Combination Chemotherapy to Treat High-risk Elderly With Non-small Cell Lung Cancer
This study will enroll elderly patients with advanced non-small cell lung cancer who are at high risk of developing chemotherapy toxicity (side effects).
- Trial name
- NCT02590003
- Testing
- Carboplatin, Nab-paclitaxel
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Quality of Life, Primary Patient Caregiver
Perceived Burden and Quality of Life of Primary Caregivers of Cancer Patients Aged 70 and Older After 5 Years of Management
Cancer is a disease that requires long-term management, especially now that medical advances have transformed most cancers from an acute to a chronic condition.
- Conditions
- Quality of Life, Primary Patient Caregiver, Cancer
- Trial name
- FARAPPAC (NCT04478903)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Octogenarian Patients With Non-metastatic Resectable Colorectal Cancer
SGA-OCRC: Prediction of 90-Day Major Adverse Postoperative Outcomes in Octogenarians With Resectable Colorectal Cancer
Octogenarian patients with colorectal cancer are a growing population with substantial heterogeneity in frailty, functional reserve, nutritional status, and comorbidity.
- Trial name
- NCT07903129
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Leukemia, Myeloid, Acute, De Novo
Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old
A phase I-II trial based on the combination of three drugs regimen LDAC or Azacitidine + Venetoclax + Quizartinib that in this population could be well tolerated by a sequential type administration.
- Conditions
- Leukemia, Myeloid, Acute, De Novo, Age More 60yr
- Trial name
- NCT04687761
- Testing
- Azacitidine, Venetoclax, Quizartinib
- Where
- 15 sites in Spain
- Volunteers
- 113 people
- Sponsor
- PETHEMA Foundation
Acute Myeloid Leukemia
Venetoclax+HMA+Aclarubicin Versus Venetoclax+HMA in Treatment-Naive Elderly Patients With AML
This research is being done to assess the therapeutic efficacy and safety of a promising regimen (Venetoclax combined with Decitabine/Azacitidine and Aclarubicin) versus Venetoclax combined with Decitabine/Azacitidine in…
- Trial name
- NCT05264883
- Testing
- Venetoclax-Decitabine/Azacitidine-Aclarubicin Association, Venetoclax-Decitabine/Azacitidine Association
- Where
- China
- Volunteers
- 170 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Head & Neck Cancer, Radiotherapy
Nimotuzumab Plus Radiotherapy in Elderly Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma
This is a prospective, single-center, open-label, single-arm phase II study. The purpose of this study is to evaluate the efficacy and safety of nimotuzumab combined with concurrent intensity-modulated radiotherapy (IMRT) in…
- Trial name
- NCRHNC (NCT07821242)
- Testing
- Nimotuzumab
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Ke Hu
Cancer Pain, Renal Insufficiency Chronic
Assessing Hydromorphone Sustained-Release Tablets in Elderly Cancer Pain Patients With Renal Insufficiency
This clinical study aims to understand whether domestic hydromorphinone sustained-release tablets are effective and safe in treating moderate to severe cancer pain in elderly patients with renal insufficiency.
- Conditions
- Cancer Pain, Renal Insufficiency Chronic, Hydromorphone Use
- Trial name
- NCT07421674
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Taian Cancer Hospital
Prostate Cancer Patients, Elderly Patients
A Dose Optimization Study of Enzalutamide in Elderly Patients With Advanced Prostate Cancer
This is a phase II, single-centre, pragmatic, non-randomized, dose escalation study to evaluate optimal dose levels of enzalutamide in elderly patients using pharmacokinetic blood sampling concentrations.
- Conditions
- Prostate Cancer Patients, Elderly Patients, Pharmacokinetic Study
- Trial name
- NCT07512076
- Testing
- Enzalutamide Dose Escalation, Standard of Care
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Sunnybrook Health Sciences Centre
Elderly, Cancer
Improving Quality of Life and Function for Older Cancer Patients Receiving Radiotherapy
This study is a first part of a larger project aiming at improving the following outcomes in older cancer patients receiving external beam radiation therapy (EBRT): quality of life, functioning and need for professional help…
- Conditions
- Elderly, Cancer, Radiotherapy Side Effect
- Trial name
- NCT03071640
- Where
- Norway
- Volunteers
- 302 people
- Sponsor
- Sykehuset Innlandet HF
Oncology, Elderly Patients
Efficacy of Adapted Physical Activity on a Walking Platform in Elderly Patients HOspitalized for Cancer Surgery
The aim of this study was to evaluate the efficacy of daily use of a walking platform to improve recovery of preoperative walking speed at hospital discharge following oncological surgery in patients aged 65 or older.
- Conditions
- Oncology, Elderly Patients, Surgery
- Trial name
- APPAHOCA-2 (NCT06201884)
- Testing
- Early rehabilitation through Adapted Physical Activity
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Francois Baclesse
Soft Tissue Sarcoma Adult
Impact of Locoregional Treatment of Soft Tissue Sarcoma on Status of Patients Aged 70 Years and Over
In order to describe functional impact of surgery in elderly patients treated for lower-limb soft-tissue sarcoma, the investigators set up this project which aims to identify prognostic factors among geriatric and functional…
- Trial name
- SARCOLD (NCT03077178)
- Testing
- Geriatric assessment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Institut Bergonié
Breast Cancer
GEriatric Determinants of Curative RAdiotherapy Scheme Choice for Breast Cancer ELderly Patient Treatment Compliance and Tolerance
This study proposes an onco geriatric evaluation (Activities of Daily Living, Instrumental Activities Of Daily Living, Mini Mental State Examination, mini Geriatric Depression Scale, Mini Nutritional Assessment, Cumulative…
- Trial name
- GERABEL (NCT02994914)
- Testing
- Onco Geriatric Evaluation
- Where
- 3 sites in France
- Volunteers
- 241 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Acute Myeloid Leukemia
Design and Validation of a Generative AI and Propensity Score Matching Model for the VEN-DEC Phase II Study in Elderly AML Eligible for Allo-SCT; Evaluation of an Exploratory Approach Respect to a Randomized Phase III Trial
To better delineate the contribution of VEN-DEC to the treatment of AML patients aged between ≥ 60 and < 75 years and deemed fit for Allo-HSCT, real-world data on a patient-level basis will be collected and utilized to generate a…
- Trial name
- VenDec-AI (NCT07420790)
- Where
- Italy
- Volunteers
- 1,941 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Lymphoma, Chemotherapy-induced Neutropenia
Danish Elder Lymphoma Patient Hematopoietic Investigation
Every year approximately 300 Danish patients die from lymphoma. The median age at diagnosis is 70 years. Lymphoma can be efficiently treated with chemotherapy, and potentially cured.
- Conditions
- Lymphoma, Chemotherapy-induced Neutropenia, Chemotherapy-Related Leukemia, Chemotherapeutic Toxicity
- Trial name
- DELPHI (NCT05245487)
- Testing
- DNA repair gene mutation analysis
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
GI Cancer
Effect of Geriatric Intervention in Frail Patients with Gastric, Biliary, and Pancreatic Cancer Receiving Palliative Chemotherapy
Gastric, biliary and pancreatic cancer are commonly malignancies from gastro- intestinal tract in Taiwan. Because lack of specific symptoms at presentation and effective screening methodology, majority of these patients are…
- Trial name
- NCT06040801
- Testing
- Frailty intervention measures
- Where
- Taiwan
- Volunteers
- 138 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Lymphocytic Leukemia
Ofatumumab as Front-Line Therapy in Treating Elderly Participants With Chronic Lymphocytic Leukemia
This phase II trial studies how well ofatumumab works as front-line therapy in treating elderly participants with chronic lymphocytic leukemia.
- Trial name
- NCT01444716
- Testing
- Ofatumumab
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- M.D. Anderson Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.