Clinical trials: Elderly Frail
Frail Elderly, Malnutrition
Healthy Life for Frail Malnourished Seniors Performed Together With Trained Lay Buddies
Background: In elderly subjects frailty and malnutrition are very common and can lead to serious health hazards, increase mortality, morbidity, dependency, institutionalization and a reduced quality of life.
- Trial name
- NCT01991639
- Testing
- Nutritional and physical activity intervention
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Depression, Sleep Quality
Effect of Music Activities on Depression and Sleep Quality in Frail Older Adults
This study aims to examine the effects of music activities on depression and sleep quality among frail older adults, and to develop a standardized music activity protocol suitable for use in adult day care centers.
- Conditions
- Depression, Sleep Quality, Frailty
- Trial name
- NCT07049445
- Testing
- Music Activity Program
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Chung Hsing University
Fraility, COPD (Chronic Obstructive Pulmonary Disease)
Respiratory Exercises in Frail Elderly COPD Patients
Purpose: This study evaluated the impact of a structured intervention on frailty, lung function, physical capacity, and dyspnea in elderly COPD patients.
- Conditions
- Fraility, COPD (Chronic Obstructive Pulmonary Disease), Older Adults (65 Years and Older)
- Trial name
- NCT07472530
- Testing
- breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Exergaming, Exercise Therapy
Comparative Effects Of Exergaming And Otago Exercise On Anticipatory Postural Control And Sensory Integration In Older Adults
This study explores whether non-immersive, interactive Exergaming using Xbox Kinect can go beyond conventional exercise by actively training the brain and body to react faster, balance smarter, and move more confidently.
- Conditions
- Exergaming, Exercise Therapy, Frail Elderly, Healthy Aging
- Trial name
- NCT07308353
- Testing
- Otago Exercise Program, Exergaming
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Cognitive Decline, Memory Loss
Effects of Music and Dance on Cognition, Frailty, and Burden in Elderly Caregivers Living in Rural Communities
This research aims to analyze the effects of senior dance on the cognition, frailty, and burden in elderly caregivers of rural communities.
- Conditions
- Cognitive Decline, Memory Loss, Frail Elderly Syndrome, Burden, Dependency
- Trial name
- NCT03068299
- Testing
- Dance, Health care guidance
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Frail Elderly Syndrome, Elderly Infection
Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly
Vitamin D has been known to influence immune response through Vitamin D Receptor in Immune Cells, but only few has been known about the effect alfacalcidol, a vitamin D analog to immune system.
- Trial name
- NCT03292744
- Testing
- Alfacalcidol
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Frail Elderly Syndrome
Effects of WBV Associated With IMT on Functionality
The pre-frail elderly are a population more vulnerable to diminished functionality and future disabilities. Thus, interventions focused on the prevention of sarcopenia are indicated to prevent dysfunction in this population.
- Trial name
- NCT03688932
- Testing
- WBV + IMT
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Functional Status, Frailty
Protocol for Inpatient Nursing Frailty Assessment (INFA)
Background: Frailty confers greater risks of negative health outcomes in hospitalised older adults. To improve care for this vulnerable population, Comprehensive Geriatric Assessment (CGA) is recommended for frail older persons.
- Trial name
- NCT06469723
- Testing
- INFA Program
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Aging, Fragility
Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals
The goal of this clinical trial is to see how small blood vessels respond to the stress of high intensity exercise, and if a safe and simple intervention called ischemic conditioning can protect blood vessels from the stress of…
- Conditions
- Aging, Fragility, Endothelial Dysfunction
- Trial name
- NCT05808686
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Pre-Frail or Frail State
Randomized Controlled Trial of Community-based Nutritional, Physical and Cognitive Training Intervention Programmes for At Risk Frail Elderly
The aims of this proposed community-based randomized controlled trial are to evaluate the effectiveness of nutritional, physical exercise and cognitive training interventions for at-risk and frail elderly, to elucidate the…
- Trial name
- FIT (NCT00973258)
- Testing
- Nutritional Intervention, Physical Exercise, Cognitive Training
- Where
- Singapore
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- National Medical Research Council (NMRC), Singapore
Mild Cognitive Impairment
Effectiveness of Tongue Resistance Exercises on Tongue and Swallowing Function in Frail Older Adults With MCI
The purpose of this study is to explore the effects of tongue resistance exercises on tongue muscle strength and swallowing function in frail older adults with mild cognitive impairment living in the community.
- Trial name
- NCT06766487
- Testing
- Tongue resistance exercises, cheek bulging exercises
- Where
- Taiwan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Chang Gung Medical Foundation
Fragility
Exercise Intervention to Reverse Frailty
The objective of this study is to evaluate a multi-component exercise intervention as an effective therapy to reverse pre-frailty phenotype in females age 65 or older.
- Trial name
- ERF (NCT02952443)
- Testing
- Exercise, Control
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Death
Risk Evaluation for Support: Predicting Elder Life in the Community Tool (RESPECT)
To develop a mortality risk prediction model that can be applied to the wide spectrum of risks that are seen in the home care setting.
- Trial name
- RESPECT (NCT02779309)
- Testing
- Home Care/RAI-HC Assessment
- Volunteers
- 486,000 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Knee Arthroplasty
A Holistic Evaluation of the Effects of Healing Nursing Care Interventions on Frail Patient Undergoing Knee Arthroplasty and Their Caregivers
This study was designed to holistically examine the effects of curative nursing care practices based on human caring theory on frail patients and their caregivers undergoing knee arthroplasty.
- Trial name
- NCT07201454
- Testing
- nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Sedentary Behavior, Frail Elderly Syndrome
Effect of an Intervention on Health in Older Care Home Residents
Care home residents spent 79% of their time being sedentary. Reduced physical activity and lack of mental stimulation causes general weakness and frailty in older adults that can result in increased healthcare needs.
- Conditions
- Sedentary Behavior, Frail Elderly Syndrome, Frailty, Lifestyle, Sedentary
- Trial name
- NCT04659694
- Testing
- Wellness programme provided by Oomph! Wellness company
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bournemouth University
Frailty Syndrome, Pre-frail Older Adults
Targeted Physical Function Exercises on Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults
The investigators will conduct a randomized controlled trial to assess the impact of targeted physical function exercises on frailty and falls in community-dwelling adults over 65 years of age.
- Trial name
- NCT06731712
- Testing
- Physical Function Exercises
- Where
- Greece
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Hellenic Mediterranean University
Medication Adherence, Medication Compliance
Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays
Background: Problems with prospective memory, which refer to the ability to remember future intentions, cause deficits in basic and instrumental activities of daily living, such as taking medications.
- Trial name
- NCT04289246
- Testing
- Medication Ambient Display (MAD)
- Where
- Mexico
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Frail Elderly, Vitamin d Deficiency
Vitamin D in Vulnerable Adults (VIVA-VA)
Vitamin D insufficiency is a problem of growing concern, given its prevalence in older persons and the association of low vitamin D with multiple major health problems, including mobility and balance deterioration and falls…
- Trial name
- VIVA-VA (NCT01170273)
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Frail Elderly Syndrome, Mood
FOCUS Guidelines and Adherence to Physical Activity in Ageing Women.
The study aimed at assessing whether the guidelines from the European project FOCUS had an effect on adherence to a physical activity program in older women.
- Conditions
- Frail Elderly Syndrome, Mood, Quality of Life, Cognitive Decline
- Trial name
- NCT03981965
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Frailty, Frailty Syndrome
Characterising Frailty Using Magnetic Resonance Imaging
Ageing is associated with the development of various negative conditions, such as frailty. Defined as a decreased ability to combat negative stressors (e.g.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- PHENOFRIM (NCT04612686)
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nottingham