Clinical trials: Elderly Patient
Postoperative Cognitive Dysfunction
Effects of Amantadine on Postoperative Cognitive Dysfunction
Post-operative cognitive dysfunction (POCD) is a fairly well-documented clinical phenomenon. Investigators will determine whether amantadine can reduce the occurrence of POCD in elderly patients with major abdominal surgery.
- Trial name
- NCT03527134
- Testing
- Amantadine
- Where
- China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Zhiyi Zuo
Distal Radius Fractures, Wrist Fracture
Unstable Distal Radius Fractures With Dorsal Dislocation in Patients Aged 18-64 Years. Volar Locking Plate (VLP) vs Closed Reduction and Percutaenous Pinning (CRPP).
120 patients age 18-64 years with dorsally displaced distal radius fractures AO-type A2, A3 and C1 are recruited from Oslo Casualty Medical Centre (Oslo Skadelegevakt).
- Conditions
- Distal Radius Fractures, Wrist Fracture, Colles' Fracture
- Trial name
- NCT04716309
- Testing
- Open reduction and volar locking plate and closed reduction and K-wires.
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Aging
Health TAPESTRY Ontario
The Health Teams Advancing Patient Experience: Strengthening Quality (Health TAPESTRY) is a community-based program led by primary care teams, that creates connections between trained community volunteers, interprofessional…
- Trial name
- NCT03397836
- Testing
- Health TAPESTRY Intervention, Usual Care
- Where
- Canada
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- McMaster University
Intraoperative Hypothermia
Research on Intraoperative Hypothermia Risk Prediction Model and Temperature Management Strategy for Elderly Patients During Surgery Based on Dynamic Incremental Training
With the support of partial dual temperature monitoring (comparing the specific difference between standardized axillary temperature monitoring and esophageal temperature), this trial is divided into the following three parts: 1.
- Trial name
- NCT06676735
- Testing
- Inflatable warming system, Prediction of intraoperative hypothermia risk, The difference between axillary temperatature and core temperature in elderly patients
- Where
- China
- Volunteers
- 1,323 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Mild Cognitive Impairment
Cognitive Assessment of Elderly Primary Care Patients
Most primary care physicians do not screen older patients for cognitive impairment. Identification of cognitive impairment may result in earlier referral for diagnostic work-up and earlier treatment and better patient outcomes.
- Trial name
- NCT01492335
- Testing
- Cognitive Report, Treatment As Usual
- Where
- United States
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cohort Studies
The Relationship Between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients
This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the the relationship between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients: a…
- Trial name
- NCT06861764
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Aged, Microsurgery
Microsurgery in the Elderly in a Private Practice Setting
This study reports the experience in free tissue transfer in the elderly population by a single surgeon in the private practice setting in Mexico city and the potential criticism that could arise from adverse events in…
- Trial name
- NCT04584723
- Testing
- Observation of flap survival and complications
- Where
- Mexico
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hospital Angeles del Pedregal
Xerosis Cutis, Dry Skin
Enhancing SKIN Health and Safety in Aged CARE
Aged long-term care receivers are affected by various adverse skin conditions like pressure ulcers, incontinence-associated dermatitis, dryness, intertrigo and many more.
- Conditions
- Xerosis Cutis, Dry Skin, Pruritus, Pressure Ulcer
- Trial name
- SKINCARE (NCT03824886)
- Testing
- Implementation of skin care algorithm
- Where
- 2 sites in Germany
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- PD Dr. Jan Kottner
Gingivitis
Silver Diamine Fluoride and Gingivitis in Geriatric Patients
Gingivitis in the geriatric population is one of the growing global public health concerns, thus finding the most effective and non-invasive approach to prevent and treat gingivitis in the geriatric population is essential to…
- Trial name
- NCT03445286
- Testing
- Silver Diamine Fluoride, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Texas A & M University Baylor College Of Dentistry
Depressive Disorder, Suicide, Attempted
Brain Markers of Suicide Risk and Psychological Pain in Elderly Depressed Patients
The main objective of this study is to show MRI functional and structural differences between depressed elderly patients with a history of attempted suicide compared to depressed elderly patients with no history of attempted…
- Trial name
- SPAD-IRM (NCT03287986)
- Testing
- MRI
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Medication Adherence, Medication Compliance
Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays
Background: Problems with prospective memory, which refer to the ability to remember future intentions, cause deficits in basic and instrumental activities of daily living, such as taking medications.
- Trial name
- NCT04289246
- Testing
- Medication Ambient Display (MAD)
- Where
- Mexico
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Bronchial Asthma
the Effect of Use of Vit d and Probiotic as a Supplementaition in the Treatment of Bronchial Asthma in Patient Aged 6 to 50 Year and Its Effect in Decrasing Excerbation.
the study of the effect of vit d and probiotic as suprplementaion in the treatment of patient with bonchial asthma and its effect in decreasing number of excerbation
- Trial name
- asthma (NCT06962761)
- Testing
- Vit D
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Delirium in Old Age
REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant
This research study will evaluate the effectiveness of postoperative administration of a drug called suvorexant, to improve postoperative sleep and decrease the severity of delirium (serious confusion) in adults 65 years and…
- Trial name
- REPOSE (NCT05733286)
- Testing
- Suvorexant 20 mg
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Duke University
Elderly, Acetabular Fractures
Acetabular Cerclage and Total Hip Arthroplasty in the Treatment of Acetabular Fractures in Elderly Patients.
We want to present the outcome of complex multifragmented acetabular fractures in the elderly treated with acetabular cerclage and total hip arthroplasty.
- Conditions
- Elderly, Acetabular Fractures, Cerclage Acetabular Fractures, Total Hip Arthroplasty
- Trial name
- jantjeVL (NCT03581669)
- Testing
- Cerclage and total hip arthroplasty
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Depression in Old Age
The Use of Collaborative Care in General Practice for Elderly Patients With Depression
The first part of this study aims to identify the occurence of depression in the elderly. In the second part, older patients with depression will be invited to a collaborative care with his or her family physician and a…
- Trial name
- NCT04078282
- Testing
- Intervention group
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Surgery, Geriatric Assessment
Implementation Pilot of Preoperative CGA Before Major Surgery
The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery.
- Conditions
- Surgery, Geriatric Assessment, Health Services Research, Implementation Science
- Trial name
- NCT06184724
- Testing
- Implementation Package for CGA, Routine Clinical Care
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Delirium - Postoperative, Delirium and Post-operative Cognitive Dysfunction (POCD)
Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients
The goal of this pilot clinical trial is to learn if personalized audio-recorded reorientation messages can be successfully implemented in general hospital wards for elderly patients after hip fracture surgery.
- Conditions
- Delirium - Postoperative, Delirium and Post-operative Cognitive Dysfunction (POCD), Delirium, Postoperative
- Trial name
- NCT07396532
- Testing
- Audio-Recorded Reorientation Intervention
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Acute Appendicitis in Elderly
Clinicopathological Aspects of Acute Appendicitis in Patients Above Age of Thirty at Sulaimani Emergency Hospital
Aims of this study are : Estimate the incidence of A.A. in patients above age of 30 y in 4 age groups . Correlate between different clinical aspects and histopathological results.
- Trial name
- NCT04033198
- Testing
- Appendectomy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Delirium
Computer-assisted Cognitive Stimulation Treatment for Delirium
The objectives of our study are to determine whether people with delirium in a subacute care unit improve after one week with non-pharmacological therapies based on improving sleep schedules, mobility, and cognitive stimulation…
- Trial name
- Delitract (NCT07563244)
- Testing
- Specific computer-based cognitive stimulation intervention, Usual care intervention
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Delirium
Testing the Validity of the "Modified Confusion Assessment Method for the Emergency Department" (mCAM-ED)"
The proposed Study validates the accuracy of the modified Confusion Assessment Method for the Emergency Department
- Trial name
- Val_mCAM-ED (NCT02782143)
- Where
- Switzerland
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland