Clinical trials: Elderly Patient
Frail Elderly w/ Multimorbidity & Functional Limitations
The PAtient-Centred Team - Effectiveness and Cost-effectiveness Study
There is an urgent need to develop new care models for patients with long-term and complex needs. Our goal is services that are seamless, pro-active and person-oriented.
- Trial name
- PACT (NCT02541474)
- Testing
- Integrated care
- Where
- Norway
- Volunteers
- 1,200 people
- Sponsor
- University Hospital of North Norway
Sarcopenia, Malnutrition
EAMA Sarcopenia in Acute Care Patients in 9+European Countries
This collaborative study in 9 geriatrics units across Europe aims to apply emerging research to clinical practice, following the "Action-Research Philosophy" (11).
- Trial name
- EAMA9+ (NCT04039620)
- Testing
- Observational study, no interventions expected
- Where
- Spain
- Volunteers
- 366 people
- Sponsor
- Parc de Salut Mar
Elderly Patients, Solid Organ Cancer
Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery
Surgical resection is one of the most important treatments for solid organ cancer. Whereas cancer recurrence and/or metastasis are the major reasons of treatment failure.
- Conditions
- Elderly Patients, Solid Organ Cancer, Surgical Resection, Epidural Anesthesia
- Trial name
- NCT03335826
- Testing
- Combined epidural-general anesthesia, General anesthesia
- Where
- 5 sites in China
- Volunteers
- 1,802 people
- Sponsor
- Peking University First Hospital
Mild Cognitive Impairment
Cognitive Assessment of Elderly Primary Care Patients
Most primary care physicians do not screen older patients for cognitive impairment. Identification of cognitive impairment may result in earlier referral for diagnostic work-up and earlier treatment and better patient outcomes.
- Trial name
- NCT01492335
- Testing
- Cognitive Report, Treatment As Usual
- Where
- United States
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Gastrointestinal Malignancy
Mobility and Activity Training (MAT) to Optimize Outcomes for Older Adult Abdominal Surgery Patients
In this pilot study a group of older adults undergoing midline laparotomy for gastrointestinal malignancy will participate in a mobility and activity training (MAT) program.
- Trial name
- MAT (NCT02007876)
- Testing
- Mobility and Activity Training
- Where
- 2 sites in United States
- Sponsor
- University of Michigan
Chronic Kidney Disease (CKD), Health Communication
Patient-centered Precision Medicine Lab Result Communication for Older Adults
For adults ≥65 years and their providers, the investigators will test the usability and design of a tool to replace standard uniform reporting of lab results to patients and their providers with a new personalized Electronic…
- Conditions
- Chronic Kidney Disease (CKD), Health Communication, Patient Comprehension
- Trial name
- NCT07391904
- Testing
- Chronic Kidney Disease (CKD) Lab Result Communication Tool
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- University of California, Los Angeles
Hodgkin Lymphoma, Adult
Elderly Hodgkin Lymphoma Patients Treated With Chemoradiotherapy
Outcome of Hodgkin lymphoma patients over than 60 years treated by chemotherapy and/or radiotherapy: retrospective analysis.
- Trial name
- HODGSA (NCT03535948)
- Where
- 2 sites in France
- Volunteers
- 90 people
- Sponsor
- Central Hospital, Nancy, France
Advance Care Planning
Advanced Care Planning for the Severely Ill Home-dwelling Elderly
This study will develop and evaluate a complex intervention to implement advance care planning for severely ill home-dwelling elderly acutely admitted to hospital, by using a cluster randomized design.
- Trial name
- NCT05681585
- Testing
- Implementation support program
- Where
- 12 sites in Norway
- Volunteers
- 2,000 people
- Sponsor
- University of Oslo
Depression Anxiety Disorder, Geriatric Diseases
A Tripartite Biopsychosocial Intervention Program Enhances Mental Health and Quality of Life in Elderly Patients With Depression Secondary to Geriatric Diseases
The biopsychosocial integrated intervention program is an effective model for improving holistic health in elderly patients with geriatric disease-related secondary depression, significantly alleviating depressive symptoms…
- Conditions
- Depression Anxiety Disorder, Geriatric Diseases, Mental Health and Quality of Life in Elderly Patients
- Trial name
- NCT07002385
- Testing
- control group, Intervention group
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Wenzhou Seventh People's Hospital
Cohort Studies
Effects of Volatile Anaesthetics on Incidence of Postoperative Depression and Anxiety in Elderly Patients
This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the impact of volatile anaesthetics on the incidence of postoperative depression and anxiety among elderly patients.
- Trial name
- NCT06307717
- Testing
- volatile anaesthetic (sevoflurane, isoflurane, desflurane)
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Chinese PLA General Hospital
Sarcopenia
The Whole Body Vibration for Sarcopenic Hospitalized Patients Aged 80+ Years
Resistance training have been recommended for sarcopenic patients. However, the whole body vibration training would further benefit for sarcopenic patients on the basis of resistance training remains unclear.
- Trial name
- NCT04637789
- Testing
- the whole body vibration, resistance training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yuxiang Liang
Heart Failure, Diastolic, Obesity
Exercise Intolerance in Elderly Patients With Diastolic Heart Failure
The purpose of this study is to examine the effects of weight loss via hypocaloric diet, aerobic exercise training, combined hypocaloric diet and exercise training, and attention control in patients with heart failure and a…
- Trial name
- SECRET (NCT00959660)
- Testing
- Exercise, Dietary Intervention, Diet and exercise
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University
Colorectal Cancer Metastatic
Radioembolization in Elderly/ Fragile Patients With mCRC
Radioembolization (RE) is a minimally invasive treatment with administration of radioactive microspheres into the hepatic artery via a microcatheter.
- Trial name
- CAIRO7 (NCT05092880)
- Testing
- radioembolization, Standard of care first-line systemic therapy
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- UMC Utrecht
Functionally-Impaired Elderly
Physical Training and Health Education in Hospitalized Elderly
The Activity in GEriatric acute CARe (AGECAR) Plus Health Education is a randomized control trial to assess the effectiveness of an intrahospital exercise and health education program during short hospital stays for improving…
- Trial name
- NCT03604640
- Testing
- Physical Training
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Dr. Jose Antonio SERRA-REXACH
Cancer Pain
Efficacy of Biofeedback-Based Serious Game for Pain Alleviation in Middle-Aged and Older Ovarian Cancer Patients: A Randomized Controlled Trial
Consistent pain affects most middle-aged and older ovarian cancer patients. Non-pharmacological pain interventions, such as serious games, offer a promising approach to alleviating this pain by providing an effective sense of…
- Trial name
- NCT06612489
- Testing
- biofeedback based dynamic-difficulty game, fixed difficulty game
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Overall Survival
Intraoperative Dexmedetomidine and Long-term Outcomes in Elderly After Major Surgery
This is a 3-year follow-up of patients enrolled in a previous randomized controlled trial which showed that intraoperative dexmedetomidine reduced delirium in elderly patients after major non-cardiac surgery.
- Trial name
- NCT04111926
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 619 people
- Sponsor
- Peking University First Hospital
Chronic Renal Insufficiency, Chronic Kidney Failure
Behaviour and Cognitive Evaluation for Dialysis Elderly Patients (BCDE)
The trial is a multicenter, prospective, randomized, open study. A total of 500 elderly patients aged over 75 years with renal insufficiency stage 5 will be included in the study after signed informed consent.
- Conditions
- Chronic Renal Insufficiency, Chronic Kidney Failure, Aged
- Trial name
- BCDE (NCT01225458)
- Testing
- shorter tests, initial complete geriatric tests, follow-up complete geriatric tests
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hip Fractures
Conventional Spinal Anaesthesia Versus Fractional Spinal Anaesthesia on Hemodynamics
compare the systemic haemodynamic response to fractional spinal anaesthesia versus conventional spinal anaesthesia , in a group of elderly and comorbid patients with hip fracture.
- Trial name
- NCT06583213
- Testing
- Fractional Spinal Anaesthesia., Conventional Spinal Anaesthesia
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Ain Shams University
Gait Disorders, Neurologic, Gait Disorders in Old Age
ExerG: Video Game-based Physical Cognitive Training for Patients: a Usability Study
Video game-based training programs, in the following referred to as "exergames" are an innovative digital training approach to simultaneously train physical and cognitive functions and increase training motivation for various…
- Conditions
- Gait Disorders, Neurologic, Gait Disorders in Old Age, Gait Disorder, Sensorimotor, Balance; Distorted
- Trial name
- ExerGetic (NCT05967078)
- Testing
- ExerG
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Frank Behrendt
Esophagus Cancer, Esophagogastric Junction Cancer
Phase II/III Study Comparing Chemoradiotherapy With Radiotherapy in Elderly Patients With Esophageal or Esophagogastric Cancer - 3JECROG P-01
Ratiotherapy alone is the current standard treatment for elderly esophageal or esophagogastric cancer in China. And Little is known about chemoradiotherapy (CRT) in elderly patients.
- Conditions
- Esophagus Cancer, Esophagogastric Junction Cancer, Radiotherapy; Complications, Chemoradiation
- Trial name
- NCT02979691
- Testing
- SIB-IMRT, S-1
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Chinese Academy of Medical Sciences