Clinical trials: Elderly People
Coronary Arterial Disease (CAD), ELDERLY PEOPLE
Seniors Integrated Longitudinal cardioVascular Evaluation of Coronary Heart Disease: a Multicenter, Prospective Registry in China (SILVER-China)
This study aims to establish a nationwide cohort and biobank of elderly patients with coronary heart disease (CHD) and to develop risk prediction models and clinical treatment optimization plans based on this data.
- Trial name
- SILVER-China (NCT06880575)
- Where
- China
- Volunteers
- 10,139 people
- Sponsor
- Beijing Hospital
Elderly People Institutionalized in Long-term Care Services
Humoral and Cellular Responses to Vaccination Against Coronavirus Disease 2019 (COVID-19) in the Very Elderly Living in Geriatric Institutions
The main objective of this study is to describe the humoral and cellular response to BNT162b2 vaccination in people over age 75 institutionalized in the long-term care units of the Paris Public Hospitals (APHP)
- Trial name
- COGEVAX-BIO (NCT04961502)
- Testing
- Blood test to describe the humoral and cellular response to vaccination BNT162b2 in the elderly
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Elderly Persons
Mandala for Anxiety, Fatigue, and Sleep
Looking at the studies on social activity programs in individuals living in nursing homes in the literature, it was seen that the studies on Mandala therapy were limited.
- Trial name
- MANDALA (NCT07145853)
- Testing
- Mandala activity
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Marmara University
Sleep Quality
Effects of Binaural Beat Music on Elderly Sleep
Background: Older people in long-term care institutions often have poor sleep quality and depression, which may negatively affect their health and welfare. Binaural beat music (BBM) has been proposed as a possible intervention.
- Trial name
- NCT05975853
- Testing
- Binaural beat music group (BBM group), Control group
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Cheng Kung University
Dementia Alzheimers, Alzheimer Disease
Person-Environment Fit for Persons With Dementia
This trial will assess feasibility of a non-pharmacological intervention for persons living with Alzheimer's disease and related dementias (ADRD) to improve behavioral and psychiatric symptoms of dementia and functional…
- Trial name
- NCT05722743
- Testing
- Harmony at HOME, National Institute on Aging Program
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Elizabeth K Rhodus
COPD Received PR, Elderly (People Aged 65 or More)
Efficacy Of Inpatient Pulmonary Rehabilitation Program In Elderly Patients With Acute Exacerbation Of COPD
The study aimed to identify the effect of early pulmonary rehabilitation in elderly patients with Acute exacerbation (AE) of COPD (AECOPD) in exercise tolerance, dyspnea, sleep quality, fatigue, and time to discharge from…
- Conditions
- COPD Received PR, Elderly (People Aged 65 or More), COPD, COPD Acute Exacerbation
- Trial name
- NCT07020182
- Testing
- physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Old Age; Debility, Loneliness
The Effect of Home Visit Supported Nursing Education Program on Some Parameters in Elderly People Living Alone at Home
It is aimed to develop healthy lifestyle behaviors of elderly people living alone at home, reduce their loneliness levels and increase their social support capacity.The research was planned as a quasi-experimental research.
- Conditions
- Old Age; Debility, Loneliness, Healthy Lifestyle
- Trial name
- NCT06517615
- Testing
- Home Visit Supported Nursing Training Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Dementia, Neurocognitive Disorders
Cognitive Stimulation in Older Adults With Alzheimer's Disease
This multicentre study, employing a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions that provide care and support services for older adults diagnosed with mild to…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT07041008
- Testing
- Digital intervention, Physical/Analogue Intervention
- Where
- 39 sites in Portugal
- Volunteers
- 514 people
- Sponsor
- Rsocialform - Geriatria, Lda
Elderly
Risk Factors for Falls After Intervention of the Urgent Medical Assistance Service (SAMU) in the Elderly Person at Home
In this project, the investigators are interested in a particular population, that of elderly subjects who used the SAMU after a fall and who are not hospitalized or are hospitalized less than 24 hours.
- Trial name
- RISING-DOM (NCT04132544)
- Testing
- standardized gerontological evaluation (EGS), Proposal for a personalized intervention plan (PIP), Follow-up
- Where
- 12 sites in France
- Volunteers
- 952 people
- Sponsor
- University Hospital, Toulouse
Subjective Cognitive Decline (SCD), Olfactory Dysfunction
The Efficacy of Modified Olfactory Training for MCI High-Risk Individuals
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can delay the progression of MCI in older…
- Conditions
- Subjective Cognitive Decline (SCD), Olfactory Dysfunction, Mild Cognitive Impairment (MCI), ELDERLY PEOPLE
- Trial name
- NCT06821828
- Testing
- Modified olfactory training device, Conventional olfactory training device
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Peking University Third Hospital
Elderly (People Aged 65 or More)
Effects of Physical Exercise and Cognitive Training on Quality of Life in Elderly Adults
The aim of the study is to investigate the effectiveness of three different types of intervention, based on physical exercise and/or cognitive stimulation or training, on quality of life, cognition and mobility, on a population…
- Trial name
- HELIOS (NCT07244536)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- Italy
- Volunteers
- 156 people
- Sponsor
- University Hospital of Ferrara
Sarcopenia
Feasibility of a Resistance Exercise and Dietary Protein Intervention in Elderly People in Practice (ProMuscle 65PK)
The purpose of this pilot study is to investigate the feasibility and potential impact of a combined resistance exercise and increased protein intake intervention in (frail) elderly, in a real-life setting.
- Trial name
- NCT02434289
- Testing
- Dietary protein products, Resistance exercise training
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Wageningen University
Coronavirus
Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2 Phase I Clinical Trial (≥60 Years Old)
Popular topic: Phase I clinical trial of recombinant new coronavirus vaccine (CHO cell) (≥60 years old) Research purpose: Main purpose: To evaluate the safety and tolerability of different doses of recombinant new coronavirus…
- Trial name
- NCT04550351
- Testing
- Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cell) low-dose group, Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cells) high-dose group
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
HIV, Aging
The Targeted Neurocognitive Training (TNT) Study
People with HIV (PWH) often suffer from cognitive impairments known as HIV-Associated Neurocognitive Disorder (HAND). Cognitive impairments in PWH are not fully captured by traditional neurocognitive assessment; thus, we must…
- Conditions
- HIV, Aging, Cognitive Function Abnormal, Cognitive Training
- Trial name
- TNT (NCT05773430)
- Testing
- Targeted Neurocognitive Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Frail Elderly Syndrome
Multifactorial Fall Prevention Program
The main objective is evaluate the effectiveness of a Multifactorial Pilot Program on the Prevention of Falls in people aged 65 or over during 4 years at Gerencia de Atención Integrada de Talavera de la Reina.
- Trial name
- Dodgers (NCT05682872)
- Testing
- Physical exercise program (VIVIFRAIL) supervised by a physiotherapist, Adequacy of the environment, Polypharmacy review
- Where
- Spain
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Castilla-La Mancha Health Service
Old Age; Debility
Older People Gait: Physiomechanics and Functionality
The aim of study is to investigate gait in active elderly people regarding the kinematic parameters of gait, indicators of physical fitness and quality of life.
- Trial name
- NCT04348539
- Testing
- Balance training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Functional Autonomy
Effects of a Serious Game With Elderly People
Assessment of the effect of a 12 weeks serious game based exercises program on physical performance in older adults living in nursing homes, in comparison with a control group that benefits from a classical exercise training…
- Trial name
- NCT03836911
- Testing
- serious game, classic program
- Where
- 15 sites in France
- Volunteers
- 136 people
- Sponsor
- University Hospital, Montpellier
Vitamin D Deficiency in Older Persons
Daily Vitamin D Supplementation Compared to a Loading Dose and Monthly Supplementation in Elderly Nursing Home Residents
Vitamin D deficiency is common in older persons, in particular in residents of nursing homes. This is mainly explained by the fact that older persons do not often go outside in the sunshine.
- Trial name
- VIDIV (NCT01168544)
- Testing
- loading dose Vitamin D and 50.000 IU vit D3/month, loading dose and 25.000 IU vit D3/month, Vitamin D 800 IU /day
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- Rijnstate Hospital
Critical Illness
Predictive Model for Mortality in Older People With Critical Illness
The present study aims to develop a predictive model to identify elderly patients with the highest likelihood of mortality upon admission to an intensive care unit.
- Trial name
- VITA (NCT06727903)
- Testing
- laboratory biomarker analysis
- Where
- 15 sites in Spain
- Volunteers
- 450 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Dementia, Elderly
Effect of Activities and Exercise on Sleep in Elderly Persons With Dementia
The purpose of the study is to determine whether individualized social activities, physical resistance training and walking, and a combination of both are effective in improving nighttime sleep in elders with dementia.
- Conditions
- Dementia, Elderly, Sleep
- Trial name
- NCT00888706
- Testing
- Control Condition, Individualized Social Activities (ISA), Physical Resistance Training and Walking (PRT/walking)
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- National Institute of Nursing Research (NINR)