Critical IllnessVITANCT06727903
Predictive Model for Mortality in Older People With Critical Illness
An observational study of Critical Illness, run by Consorci Sanitari de l'Alt Penedès i Garraf at 14 sites in Spain.
Trial summary
The present study aims to develop a predictive model to identify elderly patients with the highest likelihood of mortality upon admission to an intensive care unit. Read more about this study
- Who is it for?
- Ages 75 years and older
- Conditions the study is for
- Critical Illness
- What is being tested?
- laboratory biomarker analysis
- How many people
- 450 participants
- Where
- 14 sitesSpain
- Study dates
- 20 Mar 2025to Dec 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 75 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: Patients admitted to a Intensive Care Unit
Who may be able to join
- Men and women aged 75 or older.
- Admission to an ICU from the Emergency Department.
- Availability of or possibility to contact a participant's informant.
- Informed consent for participation in the study, either by the participant or a valid legal representative.
Who cannot join
- Participants meeting any of the following exclusion criteria will not be included in the study:
- Patients transferred to the Emergency Department from a hospital ward.
- Patients who die within the first 24 hours of ICU admission.
- Patients admitted to Step-Down Units.
- Patients requiring ICU admission for any of the following reasons:
- Orotracheal intubation or advanced cardiopulmonary resuscitation performed prior to arrival at the Emergency Department.
- AV block awaiting pacemaker implantation. Activation of the STEMI or Stroke care pathway. Post-cardiac catheterization for acute coronary syndrome.
- Participation in another clinical study involving an intervention, procedure, or visit schedule that is incompatible with the present study.
Trial locations and contacts
14 sites in 1 country. Contact the study team or a site near you to ask about taking part.
14 sites in 1 country
Spain14 sites, 14 recruiting
- Recruiting
Hospital German Trias i Pujol
Badalona, Barcelona, 08916
Clarissa Catalano, MD, 0034934651200, ccatalanonada@gmail.com
Regina Roig, MD
- Recruiting
Hospital Clinic
Barcelona
Marta Arroyo, 0034932 27 54 00, arroyo@clinic.cat
Pedro Castro
- Recruiting
Hospital de Barcelona
Barcelona
Karla Núñez, 0034932 54 24 00, kanuvaz@gmail.com
Karla Núñez
- Recruiting
Hospital de la Santa Creu i Sant Pau
Barcelona
Carles Subirà, 0034932 91 90 00, CSubira@santpau.cat
Carles Subirà
- Recruiting
Hospital de Mataró
Barcelona
Estel Güell, 0034937 41 77 00, eguell@csdm.cat
Estel Güell
- Recruiting
Hospital de Terrassa
Barcelona
Manuel Buitrago, 0034937 31 00 07, MBuitrago@CST.CAT
Manuel Buitrago
- Recruiting
Hospital del Mar
Barcelona
Ana Zapatero, 0034932 48 30 00, azapatero@psmar.cat
Ana Zapatero
- Recruiting
Hospital Dexeus Barcelona
Barcelona
Elida Amestoy, 0034 932 27 47 47, elida.amestoy@quironsalud.es
Elida Amestoy
- Recruiting
Hospital General de Catalunya
Barcelona
María Dolores Bosque, 0034900 301 013, mdbosque@quironsalud.es
María Dolores Bosque
- Not yet recruiting
Hospital General de Granollers
Barcelona
Zaira Chova, 0034938 42 50 00, zaira_gandia@hotmail.com
Zaira Chova
- Recruiting
Hospital Sagrat Cor
Barcelona
Omar Correa, 0034933 22 11 11, omar.correa@quironsalud.es
Omar Correa
- Recruiting
Clinica Girona
Girona
Mariano Rinaudo, 0034972204500, marianorinaudo@gmail.com
Mariano Rinaudo
- Not yet recruiting
Hospital Santa Caterina
Girona
Malena Tejada, 0034972 18 26 00, malenactejada@gmail.com
Malena Tejada
- Recruiting
Consorci Sanitari Alt Penedès-Garraf
Sant Pere de Ribes, Barcelona, 08810
Fernando Gerber, 0034938960025, jfgerber@csapg.cat
Noemí Casaponsa, 0034938960025 ext. 43197, recerca@csapg.cat
About this study
Official title: Development of a Predictive Model for Mortality in Patients Aged 75 or Older With Critical Illness
The present study aims to develop a predictive model to identify elderly patients with the highest likelihood of mortality upon admission to an intensive care unit.
- Conditions
- Critical Illness
- Being tested
- laboratory biomarker analysis
- Keywords
- Critical Illness, Mortality, Aged, Intensive Care Units
- Medical subject headings
- Critical Illness
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
laboratory biomarker analysisOther
Results of laboratory biomarker analysis will be analyzed as predictors for mortality
What is being measured
The primary outcome is the main question the study is designed to answer.
mortality
mortality on day 90 from admission to Intensive Care Unit
Measured: Day 90
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Dec 2024
- Study start20 Mar 2025
- Primary completionDec 2028 (estimated)
- Study completionDec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Critical IllnessStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 450 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06727903
- Sponsor's protocol ID
- CSAPG-66
- Acronym
- VITA
- Status last verified
- Nov 2026
- First submitted
- 5 Dec 2024
- Last updated
- 4 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: IPD (without personal identification data) could be shared by requirement from other researchers after the end of the study, and only for research purposes and previous approval of promotor center of the study (CSAPG). Anyway, Spanish and European Union legal policy about data protection will strictly be followed (IPD will not be transferred outside European Union).
Study at a glance
From the registry record, last updated by the sponsor on 4 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development of a Predictive Model for Mortality in Patients Aged 75 or Older With Critical Illness
- ClinicalTrials.gov ID
- NCT06727903
- Acronym / sponsor ID
- VITA / CSAPG-66
- Conditions
- Critical Illness
- Keywords
- Critical Illness, Mortality, Aged, Intensive Care Units
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 450 participants (estimated)
- Lead sponsor
- Consorci Sanitari de l'Alt Penedès i GarrafUniversity, hospital or other
- Study start
- 20 Mar 2025 (actual)
- Primary completion
- Dec 2028 (estimated)
- Study completion
- Dec 2028 (estimated)
- First posted
- 11 Dec 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The present study aims to develop a predictive model to identify elderly patients with the highest likelihood of mortality upon admission to an intensive care unit.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 75 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- Patients admitted to a Intensive Care Unit
Key inclusion criteria (4 listed)
- Men and women aged 75 or older.
- Admission to an ICU from the Emergency Department.
- Availability of or possibility to contact a participant's informant.
- Informed consent for participation in the study, either by the participant or a valid legal representative.
Key exclusion criteria (8 listed)
- Participants meeting any of the following exclusion criteria will not be included in the study:
- Patients transferred to the Emergency Department from a hospital ward.
- Patients who die within the first 24 hours of ICU admission.
- Patients admitted to Step-Down Units.
- Patients requiring ICU admission for any of the following reasons:
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| laboratory biomarker analysisResults of laboratory biomarker analysis will be analyzed as predictors for mortality | Other | – |
Primary outcome
mortality
Time frame: Day 90
mortality on day 90 from admission to Intensive Care Unit
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Nov 2026.
- Individual participant dataSharing planned: Yes. IPD (without personal identification data) could be shared by requirement from other researchers after the end of the study, and only for research purposes and previous approval of promotor center of the study (CSAPG). Anyway, Spanish and European Union legal policy about data protection will strictly be followed (IPD will not be transferred outside European Union).
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
14 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Critical Illness, run by Consorci Sanitari de l'Alt Penedès i Garraf at 14 sites in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 4 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 14 sites in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact César Gálvez, Ph.D. (+34 9389600325, cgalvez@csapg.cat), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
mortality (time frame: Day 90). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Nov 2026.