Clinical trials: Elderly People
Mental Illness Persistent
"CoMBI-SMI Multicenter Study: A Person-Centered Cognitive-Behavioral Intervention for Severe Mental Illness"
This observational multicenter study aims to evaluate whether the Cognitive Model for Behavioral Interventions - Severe Mental Illness (CoMBI-SMI) can reduce challenging behaviors and psychological symptoms in adults (aged 18 and…
- Trial name
- CoMBI-SMI (NCT07006623)
- Testing
- CoMBI-SMI
- Where
- Netherlands
- Volunteers
- 99 people
- Sponsor
- Vrije Universiteit Brussel
Pancreatic Cancer, Surgery
Quality of Life in Elderly Patients After Pancreatic Cancer Surgery
Pancreatic cancer mainly affects the elderly, with over 85% of patients diagnosed after the age of 60 and over half after the age of 70.
- Conditions
- Pancreatic Cancer, Surgery, Elderly
- Trial name
- ADL_DPC_PA (NCT06079229)
- Testing
- Phone call
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hospices Civils de Lyon
Healthy Aging, Digital Health Literacy
Digital Technology for Active and Healthy Ageing in Taiwan
Taiwan is entering a super-aged society in 2025, with more than 20% of the population aged 65 years or older. This rapid demographic shift, combined with increasing rates of chronic diseases, frailty, and dementia, has created…
- Trial name
- NCT07232667
- Testing
- Geneactiv, iMED Mobile Health Platform, iCue
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Falls Prevention, Implementation
Implementation of a Multifactorial Falls Prevention Intervention in Older Community-dWElling peRsons
Approximately 24 to 40% community-dwelling older persons fall annually, of which 21 to 45% fall recurrently. Many factors contribute to the risk of falling, such as mobility impairment, medication use, environmental issues and…
- Conditions
- Falls Prevention, Implementation, Older People
- Trial name
- BE-EMPOWERed (NCT06105437)
- Testing
- BE-EMPOWERed program
- Where
- Belgium
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy
Efficiency of Inspiratory Muscle Training in Elderly People
Efficiency of inspiratory muscle training in elderly people. Outcomes are lung function, muscle strength and chest expansion.
- Trial name
- NCT02424981
- Testing
- Threshold inspiratory muscle training
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Polypharmacy
Structured Polypharmacy Management Before Elective Non-cardiac Surgery in Frail and Elderly People
The older segment of the population is growing faster than any other segment. Older people have surgery more often than any other age group, and these older patients often take multiple medications, including medications that may…
- Trial name
- NCT03445767
- Testing
- MedSafer
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Hypertension, Systolic, Cerebrovascular Disease
Intensive Versus Standard Blood Pressure Lowering to Prevent Functional Decline in Older People
This randomized clinical trial examines if lowering and maintaining 24-hour ambulatory systolic blood pressure to <130 mmHg (intensive control) versus <145 mmHg (standard control) slows/halts the progression of deterioration of…
- Trial name
- NCT01650402
- Testing
- Anti-hypertensive therapy to SBP 130 mm Hg, Anti-hypertensive therapy to SBP 145 mm Hg
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- UConn Health
Elderly People in a Consultation Context
Validation of a Digital Multidimensional Assessment Tool for the Elderly in Geriatric Consultations
The aim of this study is to validate a digital multidimensional assessment tool for elderly people in geriatric consultations. The aim is to use a digital tablet to rapidly assess several risks (loss of functional independence…
- Trial name
- NCT06004557
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- RIVAGES
HIV Infections, Alcohol Drinking
Precision Microbiota Interventions for Senoreduction Trial
People with HIV who drink alcohol are at increased risk for accelerated aging biology, including increased immune senescence. This randomized, double-blind, crossover clinical trial evaluates two generally recognized as safe…
- Conditions
- HIV Infections, Alcohol Drinking, Aging, Immunosenescence
- Trial name
- PreMIS (NCT07462767)
- Testing
- Limosilactobacillus reuteri, Blueberry extract
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Older Adults, Loss of Autonomy
The Count Me In Program in Support of Social Participation for Older People With Loss of Autonomy
The goal of this observational study is to determine whether the Count Me In Program (Participe-Présent in French), which focuses on the strengths and power to act of older adults, can improve social participation and…
- Trial name
- NCT07440628
- Testing
- The Count Me In Program
- Volunteers
- 8 people
- Sponsor
- Université du Québec à Trois-Rivières
Dementia, Femur Fracture
Care of Older People With Cognitive Impairment or Dementia Hospitalized in Traumatology Units
This is a quasi-experimental design with repeated observations, taken at baseline, post-intervention, and at one and three months post-intervention.
- Conditions
- Dementia, Femur Fracture, Continuity of Patient Care
- Trial name
- CARExDEM (NCT04048980)
- Testing
- CARExDEM
- Where
- Spain
- Volunteers
- 432 people
- Sponsor
- Hospital Clinic of Barcelona
Norovirus Infections, Norwalk Gastroenteritis
Clinical Trial to Evaluate the Recombinant Norovirus Bivalent (GI. 1 / GII. 4) Vaccine (Hansenula Polymorpha)
Phase II clinical study will explore dose and safety, immunogenicity in 4 age groups, including 18-59 years old group, 6-17 years old group, 3-5 years old group, 6-35 months old group, with a total of 1716 subjects.
- Trial name
- NCT04941261
- Testing
- middle-dose Norovirus Bivalent (GI.1 / GII.4) Vaccine, high-dose Norovirus Bivalent (GI.1 / GII.4) Vaccine
- Where
- China
- Volunteers
- 1,716 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Cancer
E-Care Acceptability for Older People Undergoing Chemotherapy
The main objective of this pilot study is to evaluate the acceptability of clinical data collection using a semi-automated e-solution based on the use of text messaging among older adults undergoing chemotherapy treatment at home.
- Trial name
- ONCO-CHATBOT (NCT05408195)
- Testing
- CHATBOT use
- Where
- France
- Sponsor
- University Hospital, Toulouse
Crohn's Disease
Study of Bacteroides Thetaiotaomicron in Young People Aged 16 to 18 Years With Stable Crohn's Disease
The purpose of this study is to assess the safety and tolerability of Bacteroides thetaiotaomicron (Thetanix®)) capsules in young people aged 16 to 18 years with stable Crohn's disease.
- Trial name
- NCT02704728
- Testing
- Thetanix
- Where
- 5 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- 4D pharma plc
Undernutrition, Aging
Feasibility and Effectiveness of Nutritional Telemonitoring in Community-dwelling Elderly.
An optimal nutritional status is essential for healthy ageing. Telemonitoring might contribute to maintaining or improving nutritional status in elderly people.The objectives of this effect study are to test the feasibility and…
- Trial name
- NCT03240094
- Testing
- Nutritional telemonitoring
- Where
- Netherlands
- Volunteers
- 213 people
- Sponsor
- Wageningen University
Acute Myeloid Leukemia
Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
This phase II MyeloMATCH treatment trial compares ASTX727 with standard duration versus shorter duration of venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML).
- Trial name
- NCT07437950
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Decitabine and Cedazuridine
- Where
- 46 sites in United States, Puerto Rico
- Volunteers
- 126 people
- Sponsor
- National Cancer Institute (NCI)
Polypharmacy (People Under Treatment With 5 or More Drugs), Elderly (People Aged 65 or More)
Prevalence of Inappropriate Prescriptions and Omitted Therapies in Hospitalized Elderly: STOPP/START Criteria Analysis
Evaluate the prevalence of potentially inappropriate prescriptions (PIPs) and potential omitted prescriptions (PPOs) in elderly patient upon admission to the acute geriatric department, based on adherence or non-adherence to the…
- Conditions
- Polypharmacy (People Under Treatment With 5 or More Drugs), Elderly (People Aged 65 or More), Deprescribing, Hospitalization
- Trial name
- SPIna (NCT07202962)
- Testing
- medication review and deprescribing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
Dementia, Undernutrition
nuTritiOn and deMentia AT hOme (TOMATO)
The purpose of this study is to refine, implement and assess the acceptability and feasibility of an existing nutrition intervention applied to people living with dementia receiving home care.
- Trial name
- TOMATO (NCT05866094)
- Testing
- Nutritional Intervention
- Where
- 5 sites in United Kingdom
- Volunteers
- 139 people
- Sponsor
- Bournemouth University
Idiopathic Normal Pressure Hydrocephalus (INPH), Gait Disorders, Neurologic
Unsteady Gait in Older People May be a Common and Treatable Neurological Disease Associated With Increased Mortality
We live in an aging population and a third of the older population has a gait disorder that may cause institutionalization, and increased mortality.
- Conditions
- Idiopathic Normal Pressure Hydrocephalus (INPH), Gait Disorders, Neurologic, Gait Disorders in Old Age
- Trial name
- VESPR2 (NCT07137403)
- Where
- Sweden
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University
Frailty, Disability Physical
Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
According to the INE in 2021, more than 9 million people are currently over 65 years of age. This means that more than 1 million are frail and almost 4 million are pre-fragile only in Spain.
- Conditions
- Frailty, Disability Physical, Old Age; Atrophy
- Trial name
- PRICA-POWFRAIL (NCT05772910)
- Testing
- EDUcation, EXERcise, EDU-EXER
- Volunteers
- 110 people
- Sponsor
- University of Cadiz