Clinical trials: Elderly Persons
Telemedicine
Medical Telemonitoring Plus Individual Teleconsultation in Elderly
The aim of this study is to explore the requirements and conditions of medical teleconsultation and remote diagnostics (telemonitoring) of older people in the residential environment with an emphasis on the need for adaptation…
- Trial name
- NCT02196428
- Testing
- Telemonitoring and Teleconsultation
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Frailty
A Nurse-led Intervention on Frailty Status of Ethiopian Older Persons
The goals of this study are to design, implement, and evaluate the effects of a nurse-led intervention on the frailty and quality of life of older persons living in the community in Ethiopia.
- Trial name
- NCT05754398
- Testing
- six independent and interconnected educational training sessions
- Where
- Ethiopia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Wollongong
Cerebrovascular Disorders
Blood Pressure Reduction to Limit the Evolution of Vascular Brain Lesions in Elderly Individuals
The purpose of the study is to test the hypothesis of slowing the progression of White Matter Lesions (WML) by lowering blood pressure (BP) in patients with cognitive complaints and a moderate to high grade of WML on brain MRI.
- Trial name
- LEOPOLD (NCT02472028)
- Testing
- blood pressure lowering algorithm, usual strategy
- Where
- 2 sites in France
- Volunteers
- 820 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pre-Hypertension
Respiratory Muscle Training and Intermittent Hypoxia: Additive Health Effects?
The prevalence of pre-hypertension and hypertension in the elderly is very high. Apart from medication, physical exercise training is a potential strategy to reduce blood pressure, however, the ability to perform exercise can be…
- Trial name
- NCT03313284
- Testing
- RMT, RMT + IH, Control
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Swiss Federal Institute of Technology
Anxiety Depression (Mild or Not Persistent)
Life Satisfaction and Psychopathology in Institutionalized Elderly People
The present study attempted to test the benefits of a Mindfulness-Based Stress Reduction (MBSR) program in Portuguese institutionalized elderly people, as a way to improve life satisfaction and reduce psychopathology.
- Trial name
- NCT02774018
- Testing
- Mindfulness-Based Stress Reduction (MBSR) program
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Irmandade da Misericórdia de Albergaria-a-Velha
Elderly, Wrist Fracture
Evaluation of Health and Social Interventions Aimed to Old People Discharged From Hospital After a Hip or Wrist Fracture Due to a Fall
Objectives: To describe social and health care provided to our older patients who have been admitted in the emergency department (ED) after suffering from a hip or wrist fracture due to a fall.
- Conditions
- Elderly, Wrist Fracture, Hip Fracture
- Trial name
- NCT02802358
- Testing
- Surgery or non-invasive procedure (reduction of the fracture, immobilization, stabilization)
- Volunteers
- 1,824 people
- Sponsor
- Hospital Galdakao-Usansolo
Musculoskeletal Pain, Musculoskeletal Pain Disorder
Exergaming Experience of Older People With Chronic Musculoskeletal Pain
Chronic musculoskeletal pain is debilitating and can lower the quality of life in older people. Therapeutic benefits have been reported from exergaming used as an intervention for rehabilitation or alternative to exercise.
- Trial name
- NCT04029285
- Testing
- Exergaming
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Teesside University
Sarcopenia, Malnutrition
EAMA Sarcopenia in Acute Care Patients in 9+European Countries
This collaborative study in 9 geriatrics units across Europe aims to apply emerging research to clinical practice, following the "Action-Research Philosophy" (11).
- Trial name
- EAMA9+ (NCT04039620)
- Testing
- Observational study, no interventions expected
- Where
- Spain
- Volunteers
- 366 people
- Sponsor
- Parc de Salut Mar
Frail Elderly Syndrome, Mild Cognitive Impairment
Spanish Linguistic Validation, Validity and Reliability Test of Frail´BESTest in Elderly Institutionalized Frail People
The aging of the global population presents significant social and health challenges. In Aragón, 15% of the population is between 65 and 79 years old, and the over-aging index is 16.6%, higher than the national average.
- Trial name
- NCT06438718
- Where
- Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Hip Fractures
Effect of a Robotic Platform for Hip Fracture Rehab
Hip fracture is one of the most common traumas associated with falls in the elderly, severely affecting the patient's mobility and independence.
- Trial name
- NCT05079555
- Testing
- Robotic rehab
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Werium Assistive Solutions
Care-resistant Behavior, Dementia
Reducing Care-Resistant Behaviors During Oral Hygiene in Persons With Dementia
The main purpose of this study is to test a method of providing mouth care to persons with dementia who live in nursing homes. The method of providing mouth care is designed to reduce fear in persons with dementia, so that these…
- Trial name
- NCT01363258
- Testing
- Care-resistant mouth care (MOUTh), Evidence-based mouth care
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Hypertension, Elderly
Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population
Introduction: High blood pressure especially systolic hypertension is a common condition in the elderly and is considered as a major determinant not only of cardiovascular (CV) morbidity and mortality, but also of several other…
- Conditions
- Hypertension, Elderly, Cardiovascular Mortality, Cognitive Impairment
- Trial name
- PARTAGE (NCT00901355)
- Where
- 6 sites in France, Italy
- Volunteers
- 1,130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Cognitive Dysfunction
Postoperative Cognitive Dysfunction as Geriatric Syndrome
This study is testing cognitive function before and after the surgery, with patient's informed consent. Patients of interest are 65 year or older, undergoing surgery in general or regional anesthesia.
- Trial name
- NCT05648890
- Where
- Czechia
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Pancreatic Cancer Resectable, Pancreatic Cancer Stage II
Neoadjuvant Chemotherapy for Elderly with Pancreatic Head Cancer
The goal of this observational retrospective cohort study is to evaluate the efficacy and safety of neoadjuvant chemotherapy (NAT) in elderly patients with resectable or borderline resectable (BR) pancreatic ductal adenocarcinoma…
- Conditions
- Pancreatic Cancer Resectable, Pancreatic Cancer Stage II, Neoadjuvant Therapy, Elderly
- Trial name
- PEACE (NCT06868693)
- Testing
- Neoadjuvant Chemotherapy (NAT) Group
- Volunteers
- 240 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Pneumococcal Infectious Disease
Phase II Clinical Trial of 24-valent Pneumococcal Polysaccharide Conjugate Vaccine
A phase II clinical trial of a 24-valent pneumococcal conjugate vaccine (PCV24) developed by Shanghai Reinovax Biologics Co., LTD will be conducted in Chinese adults aged 18 years and older.
- Trial name
- NCT06678620
- Testing
- Reinovax PCV24 formulation 1, Reinovax PCV24 formulation 2, Reinovax PCV24 formulation 3
- Where
- 2 sites in China
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- Reinovax Biologics Co., LTD
Polypharmacy (People Under Treatment With 5 or More Drugs), Elderly (People Aged 65 or More)
Prevalence of Inappropriate Prescriptions and Omitted Therapies in Hospitalized Elderly: STOPP/START Criteria Analysis
Evaluate the prevalence of potentially inappropriate prescriptions (PIPs) and potential omitted prescriptions (PPOs) in elderly patient upon admission to the acute geriatric department, based on adherence or non-adherence to the…
- Conditions
- Polypharmacy (People Under Treatment With 5 or More Drugs), Elderly (People Aged 65 or More), Deprescribing, Hospitalization
- Trial name
- SPIna (NCT07202962)
- Testing
- medication review and deprescribing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
Accidental Falls
The Effectiveness of a Self-managed Digital Exercise Programme to Prevent Falls in Older Community-dwelling People
The overall aim of the study is to evaluate the effectiveness of a digital self-management exercise program in preventing falls in community dwelling older people.
- Trial name
- SafeStepRCT (NCT03963570)
- Testing
- Safe Step - digital exercise program, Control group
- Where
- Sweden
- Volunteers
- 1,628 people
- Sponsor
- Umeå University
HPV Infection, HPV-Related Carcinoma
To Evaluate the Safety and Immunogenicity of 15-valent HPV Recombinant Vaccine in Chinese People Aged 9-45 Years
To evaluate the safety and Immunogenicity of 15-valent HPV vaccine in 9-45year-old participants.
- Conditions
- HPV Infection, HPV-Related Carcinoma, HPV-Related Intraepithelial Neoplasia, Genital Wart
- Trial name
- NCT06756269
- Testing
- Medium dose for 15-HPV vaccine, High dose for 15-HPV vaccine, 9-HPV vaccine
- Where
- China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Norovirus Infections, Norwalk Gastroenteritis
Clinical Trial to Evaluate the Recombinant Norovirus Bivalent (GI. 1 / GII. 4) Vaccine (Hansenula Polymorpha)
Phase II clinical study will explore dose and safety, immunogenicity in 4 age groups, including 18-59 years old group, 6-17 years old group, 3-5 years old group, 6-35 months old group, with a total of 1716 subjects.
- Trial name
- NCT04941261
- Testing
- middle-dose Norovirus Bivalent (GI.1 / GII.4) Vaccine, high-dose Norovirus Bivalent (GI.1 / GII.4) Vaccine
- Where
- China
- Volunteers
- 1,716 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Osteoarthritis
Visual Feedback Non-weight Bearing Exercise on the Elderly With Knee Osteoarthritis.
Degenerative knee arthritis is the most common chronic arthritis disease. Once the elderly suffer from this disease, it will accelerate the loss of body function and autonomy.
- Trial name
- NCT04919486
- Testing
- visual feedback with non-weight bearing exercise, elastic band exercise
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
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