Clinical trials: Elderly Persons
Alzheimer Disease
Nonverbal Communication in Aged People
Musical interventions improve the emotional state of patients with Alzheimer's disease (AD) while having a positive impact on the caregiver's well-being.
- Trial name
- MAMUS (NCT04146688)
- Testing
- Music Balance Board
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Lille
Surgery, Old Age; Debility
Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM).
Elderly people (EP) have increased, as well as life expectancy at birth. In Chile there are more than 2 million 800 thousand EP, which corresponds to 1/6 of the Chilean population.
- Conditions
- Surgery, Old Age; Debility, Frail Elderly Syndrome, Post-Operative Confusion
- Trial name
- APOPM (NCT04770259)
- Testing
- Timely pre-surgical conditioning
- Where
- 2 sites in Chile
- Volunteers
- 87 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Falls in the Elderly
Evaluating the Impact of "CHUT OTONOM®" Footwear on the Spatio-temporal Parameters of Walking and the Risk of Falls in Elderly People at High Risk of Falling.
Footwear is one of the extrinsic factors that can cause falls in older adults. Indeed, ill-fitting or worn shoes or slippers that do not support the foot properly, have slippery soles or high heels can contribute to falls.
- Trial name
- CHAUSS-THERA (NCT07366424)
- Testing
- "CHUT OTONOM®" shoes from Innothera Laboratories
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Lille
LLM-based AI Dialogue Bot, Depression
Young People Aged 18-25 With Depression or Anxiety Mood Participate in an LLM-based Digital Dialogue Intervention Study
This study is a 28-day randomized controlled trial (RCT). Residents were randomly assigned to an intervention group or a waiting group according to the order in which they were successfully contacted by the staff, and each user…
- Conditions
- LLM-based AI Dialogue Bot, Depression, Anxiety
- Trial name
- NCT06346496
- Testing
- Douyin Xinqing AI dialog bot, Douyin Xinqing AI dialog bot for delayed intervention
- Where
- China
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- Institute of Psychology, Chinese Academy of Sciences
Sleep Disturbance
Self-Management of Sleep Among Older Adults
The purpose of this study is to test the feasibility of older persons use of a personal sleep monitoring device(PSMD)to improve self-management of sleep.
- Trial name
- NCT03837249
- Testing
- Personal Sleep Monitoring
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Mild Cognitive Impairment, Depressive Symptoms
Homebound Elderly People Psychotherapeutic Intervention
This study aims to develop, implement, and assess the feasibility, acceptability, and preliminary efficacy of a 10-week structured and individualized cognitive-emotional intervention program for homebound older adults with Mild…
- Conditions
- Mild Cognitive Impairment, Depressive Symptoms, Anxiety State
- Trial name
- HEPPI (NCT04967378)
- Testing
- HEPPI
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- University of Coimbra
Adverse Effects
Effects of Discontinuation of Benzodiazepine-derivative Hypnotics on Cognitive and Motor Functions in Elderly Persons
Benzodiazepines (BZDs) have been reported to cause negative impacts on motor as well as cognitive functions, which in turn could result in lethal incidents including falls especially in the elderly.
- Trial name
- NCT00707915
- Testing
- Drug: Benzodiazepine (listed out below)
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Minamihanno Hospital
Dementia
REspectful CAring for the AGitated Elderly
The treatment of Behavioural and Psychological Symptoms of Dementia (BPSD) continue to raise difficult problems. Both the pharmacologic and non-pharmacologic therapies often fail to achieve the expected results.
- Trial name
- RECAGE (NCT03507504)
- Testing
- SCU-B
- Where
- 12 sites in Belgium, France and 5 more
- Volunteers
- 500 people
- Sponsor
- Fondazione Europea di Ricerca Biomedica Ferb Onlus
Deglutition Disorders
Design and Development of a Functional Plant-based Beverage Formulated According to the Main Nutritional Guides for Early Elderly Requirements to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing
Populations around the world are aging and this demographic transition will impact almost every aspect of society. Furthermore, the COVID-19 pandemic has highlighted the seriousness of gaps in policies, systems and services.
- Trial name
- IMMUGOLD (NCT06445309)
- Testing
- Sensory test of functional plant-based drink
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Brain Injuries, Cognitive Impairment
Occupational Therapy and Cognitive Challenges After Brain Injury
Background: There is a need for standardized interventions in community rehabilitation that can improve everyday task performance for older adults with cognitive challenges after acquired brain injury.
- Trial name
- NCT05148247
- Testing
- The Perceive, Recall, Plan and Perform System of Intervention
- Where
- 2 sites in Norway
- Volunteers
- 6 people
- Sponsor
- Norwegian University of Science and Technology
Physical Inactivity
A RCT Evaluating a Chatbot in Increasing Physical Activity Among Older Adults
This study will compare the efficacy of a Chatbot-delivered stage of changes (SOC)-tailored online intervention (intervention group) versus a Chatbot-delivered non-SOC-tailored online intervention in increasing the prevalence of…
- Trial name
- NCT06641492
- Testing
- Chatbot-delivered interventions tailored to one's stage of changes, Chatbot-delivered standard interventions
- Where
- Hong Kong
- Volunteers
- 278 people
- Sponsor
- Chinese University of Hong Kong
Old Age; Dementia
Tango for Older People With Dementia
Cognitive impairment (CI) is the leading cause of loss of autonomy and has a huge impact on physical performance and quality of life (QOL) in older people.
- Trial name
- NCT05744011
- Testing
- Tango intervention, Adapted Physical Activity
- Where
- 2 sites in France
- Volunteers
- 124 people
- Sponsor
- University of Burgundy
Cognitive Function, Metabolic Improvements
B-vitamins Treatment for Improvement of Cognitive Function
Observation studies documented a correlation between plasma concentrations of homocysteine and cognitive decline with age. The study hypothesis was that high doses of B-vitamins (as effective homocysteine lowering treatment) can…
- Trial name
- NCT01095211
- Testing
- B-vitamin complex
- Where
- Germany
- Volunteers
- 79 people
- Sponsor
- Universität des Saarlandes
Frailty At Older Adults
Telerehabilitation on Physical Fitness, Functional Status, and Quality of Life in Frail Older Adults
The goal of this randomized controlled trial (RCT) is to analyze whether the effectiveness of a synchronous telerehabilitation program is better than a face-to-face physical therapy program in improving the physical fitness…
- Trial name
- Teleactivate 3 (NCT06784245)
- Testing
- TeleActivate
- Where
- Chile
- Volunteers
- 58 people
- Sponsor
- Marina Alvarado
Physical Activity and Wellbeing, Whole Health
Online Mindfulness-based Dance/Movement Therapy on Physical Activity and Whole-Person Health in Older Adults
This randomized controlled trial will examine whether an online, group-based Mindfulness-based Dance/Movement Therapy (M-DMT) intervention can increase physical activity and improve whole-person health among sedentary older…
- Trial name
- MOVE WELL (NCT07852572)
- Testing
- Mindfulness-based Dance/Movement Therapy, Stony Brook Health Education Program (HEP)
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Drexel University
Age-Related Memory Disorders
Effectiveness of a Cognitive Training Program (UMAM Method) in Elderly People Without Dementia
The study is oriented to analyze the effectiveness of a cognitive training method (UMAM) on cognitive functions, subjective memory and mood state in elderly people without dementia.
- Trial name
- NCT04245579
- Testing
- Multifactorial Memory Training Program (UMAM method)
- Where
- Spain
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Madrid Salud
Acute Myeloid Leukemia
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
This phase II MyeloMATCH treatment trial studies how well ASTX727 and venetoclax plus enasidenib works compared to ASTX727 and venetoclax alone for the treatment of older patients with newly diagnosed acute myeloid leukemia (AML)…
- Trial name
- NCT06672146
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy
- Where
- 138 sites in United States, Puerto Rico
- Volunteers
- 93 people
- Sponsor
- National Cancer Institute (NCI)
Multiple Conditions, Coronary Heart Disease
Improving Monitoring of Patients Receiving Case Management
The UK population is ageing and the likelihood of having a long term health condition increases with age. Three out of every five people over 60 in the UK have a long term condition.
- Conditions
- Multiple Conditions, Coronary Heart Disease, Diabetes, Hypertension
- Trial name
- NCT01597882
- Where
- 2 sites in United Kingdom
- Volunteers
- 114 people
- Sponsor
- University of Southampton
FRAILTY
FRED Exergame Including Biofeeback Supervision
A pilot six-week randomised controlled trial was carried out introducing biofeedback with physiological constants as follows: systolic blood pressure, diastolic blood pressure, heart rate and blood oxygen saturation in the…
- Trial name
- NCT03425227
- Testing
- FRED EXERGAME
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Begoña Garcia Zapirain
Falls
VISIBLE Study (Visual Intervention Strategy Incorporating Bifocal & Long-distance Eyewear)
The purpose of this study is to determine whether the provision of supplementary plain distance glasses for outdoor use to older users multifocal glasses will reduce falls rates over a 12 month period.
- Trial name
- VISIBLE (NCT00350389)
- Testing
- Outdoor use of plain distance glasses with counselling
- Where
- Australia
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
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