Clinical trials: Elderly Persons
Frail Elderly Syndrome, Sarcopenia
Physical Fitness, Body Composition and Frailty in Elderly People.Exercise Program Effecsts. EXERNET Elder 3.0
One of the major changes occurring in developed societies is a significant ageing of the population. Nowadays, because of an enhanced life expectancy, 17% of the Spanish population is composed of people over 65 and the number is…
- Conditions
- Frail Elderly Syndrome, Sarcopenia, Physical Activity
- Trial name
- EXERNETElder (NCT03831841)
- Testing
- Multicomponent exercise programe
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Palliative Care, Nursing Homes
Interventional Research With Mixed Methods on an Early Integrated Palliative Approach in Nursing Home
The national context of the end of life of elderly people living in Nursing Home (NH) is concerning. A quarter of NH residents die each year representing a quarter of annual deaths in France of all ages.
- Conditions
- Palliative Care, Nursing Homes, Aged
- Trial name
- NCT04708002
- Testing
- early integrated palliative approach model
- Where
- 3 sites in France
- Volunteers
- 3,500 people
- Sponsor
- Maison Médicale Jeanne Garnier
Cognitive Decline, Cognitive Deficit
Validation Study SCOBES-AR
Purpose of the study The purpose of this study is to evaluate five tests to see if they are suitable for the early detection of cognitive impairment in people over the age of 60.
- Conditions
- Cognitive Decline, Cognitive Deficit, Cognitive Impairment
- Trial name
- NCT04204239
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Pneumonia, Respiratory Tract Diseases
Phase Ⅰa Clinical Trial of a Pneumococcal Vaccine
Infections with Streptococcus pneumoniae often cause serious health problems, especially for infants and the elderly.Failure to cover all polysaccharide types is an even greater problem with adults than with children.
- Conditions
- Pneumonia, Respiratory Tract Diseases, Respiratory Tract Infections
- Trial name
- PⅠCTPV (NCT04087460)
- Testing
- Protein based pneumococcal vaccine(Low dose), Protein based pneumococcal vaccine(Middle dose), Protein based pneumococcal vaccine(High dose)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Old Person
Evaluate the Link Between the Characteristics of Oral Physiology and the Formation of the Food Bolus During the Consumption of Dairy Products in Elderly People
The aim of this study is to understand how dairy products enriched in minerals and proteins are broken down in the mouth. More specifically, investigators wish to evaluate the link between oral physiology (salivation and…
- Trial name
- AlimaSSenSLait (NCT03227913)
- Testing
- Two samples of saliva, Chewing behaviour, Study of the food bolus
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Dementia, Mild Cognitive Impairment
Dual-Task Training for People With Mild Cognitive Impairment and Mild Dementia
Evidence shows that people with dementia have a higher prevalence of sleep disturbance, cognitive decline, behavioral disturbance, and experience motor dysfunction. These symptoms are interrelated.
- Conditions
- Dementia, Mild Cognitive Impairment, Older Adult
- Trial name
- DTT (NCT06348810)
- Testing
- Dual-task training, Cognitive training, Motor training
- Where
- Indonesia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Under-nutrition or Risk of Undernutrition
Clinical and Medico-economic Evaluation of Taken Care Associating Nutritional Support and Adapted Physical Activity for Malnourished, or at Risk of Undernutrition, Elderly People on Discharge From Hospital
In the hospital, one out of every two elderly people is malnourished. This condition of undernutrition generally worsens during hospitalization, where the effects of polypathology and psychological distress are added.
- Trial name
- NUTRIACTIF (NCT03979560)
- Testing
- Intervention
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Gérond'if
Multimorbidity, Aged
Nursing Model and Health Outcomes of Elderly People with Multimorbidity: a Quasi-experimental Study
The goal of this quasi-experimental study is to analyze the effect of organizing nursing care according to the primary nursing model on therapeutic self-care and satisfaction with nursing care for elderly people with…
- Conditions
- Multimorbidity, Aged, Patient Outcome Assessment
- Trial name
- NCT06702150
- Testing
- Changing the nursing care model to the primary nursing model
- Where
- Portugal
- Volunteers
- 206 people
- Sponsor
- Hospital da Luz, Portugal
Healthy Young, Older People With Cardiovascular Disease Risk
Watermelon and Beetroot Products on Endothelial Function
Cardiovascular disease is the main cause of death worldwide. Endothelial dysfunction is the first step to development of cardiovascular diseases.
- Trial name
- NCT04781595
- Testing
- Watermelon, Beetroot, Watermelon + beetroot
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Advanced Cancer
ALIGN for Older Adults With Cancer in SNFs
The goal of this clinical trial is to learn if it is possible to deliver a palliative care intervention called ALIGN (Assessing and Listening to Individual Goals and Needs) to hospitalized older adults with advanced cancer who…
- Trial name
- ALIGN (NCT06616298)
- Testing
- Assessing and Listening to Individual Goals and Needs (ALIGN)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Frail Elderly, Dual Task Exercises in Elderly People
FreeFrail Project: A Multicomponent Intervention for the Management of Frailty in Primary Care: A Randomized Controlled Trial
The primary aim is to assess the effectiveness of a multicomponent intervention including dual-task exercise in improving functionality and cognitive performance and in reducing frailty among community-dwelling adults aged ≥65…
- Conditions
- Frail Elderly, Dual Task Exercises in Elderly People, Exercise Training, Frailty
- Trial name
- NCT07205016
- Testing
- Dual task exercise, Otago exercise
- Volunteers
- 220 people
- Sponsor
- Universitat de Lleida
Removable Dental Prosthesis, Dental Restoration
Impact on General Functionality of an Immediate Prosthetic Functionalization Protocol in People Over 70 Years of Age With Deficient Removable Prostheses
Title: Evaluation of the impact on general functionality of the application of an immediate prosthetic functionalization protocol, in patients with deficient removable prostheses, compared with the conventional treatment that is…
- Conditions
- Removable Dental Prosthesis, Dental Restoration, Elderly, Functional Status
- Trial name
- NCT05595304
- Testing
- prosthetic refunctioning, conventional prosthetic treatment
- Where
- Chile
- Volunteers
- 108 people
- Sponsor
- Gerardo F Fasce Pineda, MD
Refractive Errors
Cognitive Level Enhancement Through Vision Exams and Refraction
The investigators aim to conduct a mixed-method study in which a randomised controlled trial (RCT) and a descriptive qualitative study will be conducted.
- Trial name
- CLEVER (NCT05458323)
- Testing
- Free near and Distance Vision glasses
- Where
- India
- Volunteers
- 820 people
- Sponsor
- Queen's University, Belfast
Colorectal Cancer, Advanced Adenocarcinoma
Retrospective Analysis of Colorectal Cancer Screening Results
The purpose of this study is to retrospectively analyze colorectal cancer screening data of 40-74 year old population in Shipai Town, Dongguan City.
- Conditions
- Colorectal Cancer, Advanced Adenocarcinoma, Hyperplastic Polyp, Colorectal Neoplasms
- Trial name
- NCT05374369
- Testing
- SDC2 Gene Methylation Test and Q-FIT Test, Colonoscopy and/or pathological examination
- Where
- China
- Volunteers
- 822 people
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Balance
Detection of Balance in the Elderly Under the Influence of Stress
The aging process involves physiological changes in organs and tissues that can evolve towards fragility and increased risk of falls.
- Trial name
- DEPIE (NCT06682754)
- Testing
- Stress
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Aging, Fall
Design and Implementation of a Physical Exercise Program With Virtual Reality to Improve Functional Capacities in Older People.
TITLE: Desing and implementation of a Immersive Virtual Reality exercise program to improve balance in older people INTRO: Older people grow around the world at a faster rate than any other age group, resulting in an accelerated…
- Conditions
- Aging, Fall, Quality of Life
- Trial name
- NCT04336670
- Testing
- Immersive Virtual Reality exercise program, Usual care
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pablo Campo-Prieto
Diabetes Mellitus, Type 2
A Study to Test How Well Empagliflozin Works in Japanese People With Type 2 Diabetes Who Are Older Than 65 Years
This study is to assess the efficacy of empagliflozin 10 mg after 52 weeks compared to placebo in elderly patients with Type 2 diabetes mellitus (T2DM) and to explore if empagliflozin has any impact on patient physical condition…
- Trial name
- NCT04531462
- Testing
- Empagliflozin
- Where
- 18 sites in Japan
- Volunteers
- 129 people
- Sponsor
- Boehringer Ingelheim
Nutrition Disorders in Old Age
Effects of Dairy- and Berry-based Snacks on Nutritional and Functional Status and Quality of Life in Older People
Malnutrition or its risk is common among older people, especially among those receiving home care services. It impairs the quality of life of the older people and results in significant costs to society.
- Trial name
- MAVIRE1 (NCT03352388)
- Testing
- Dairy- and berry-based snacks
- Where
- Finland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Adverse Effect and Immunogenicity of Vaccine
Immunogenicity and Safety of A Lyophilized Purified Human Diploid Cell Rabies Vaccine .
Rabies is caused by rabies virus with a 100% mortality rate in humans. Most of cases occur in Africa and Asia, mainly in underserved populations. Rabies is a vaccine-preventable disease in both humans and animals.
- Trial name
- NCT03971370
- Testing
- Human diploid cell rabies vaccine (Minhai Biothechnology Co., Ltd), Human diploid cell rabies vaccine (Chengdu Kanghua Biological Products Co., Ltd.)
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Elderly (People Aged 65 or More)
Acute Effects of Motor Imagery and Action Observation in the Elderly: Single-Blind Randomized Controlled Trial
The aim of this study is to investigate the effects of acute action observation, motor imagery, exercise, and combined exercise training on parameters such as balance, reaction time, flexibility, fear of falling, cognitive…
- Trial name
- NCT07016061
- Testing
- Motor İmagery Group, Action Observation Group, Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
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