Clinical trials: Elderly Persons
Balance, Falls Prevention
Keep-On-Keep-Up (KOKU)
Falls are the primary cause of fatal and non-fatal accidental injuries in older adults. Around a third of community-dwelling older adults fall per year with high associated personal and societal costs.
- Conditions
- Balance, Falls Prevention, Functional Decline
- Trial name
- NCT06687135
- Testing
- KOKU, FaME / OTAGO leaflet and AGE UK Stay Steady Leaflet
- Where
- 2 sites in United Kingdom
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Periodontal Diseases, Malnutrition
The Association Between Periodontal Disease and Malnutrition in a Group of Elderly People in Thailand.
This study will be determine the association between periodontitis and malnutrition status in older adult.
- Trial name
- NCT05129826
- Testing
- the association between periodontitis and malnutrition status
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Depressive Symptoms
Collaborative Stepped Care and Peer Support Programme for Older People At-Risk of or With Depression
To develop a viable and sustainable best practice model to promote elderly mental wellness and prevent elderly depression for Hong Kong, the Hong Kong Jockey Club Charities Trust has initiated a pilot holistic support project…
- Trial name
- JCJoyAge (NCT03593889)
- Testing
- Collaborative stepped care and peer support programme, Treatment as usual
- Where
- 8 sites in Hong Kong
- Volunteers
- 3,702 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
HIV Infections, COVID-19
Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in People Aged ≥18 Years With HIV Infected
Evaluation of immunogenicity and safety of the subjects aged 18 years and above with HIV-infected recruited to receive three doses of inactivated COVID-19 vaccine on day 0, day 21 and day 111, respectively .
- Trial name
- NCT05075044
- Testing
- Inactivated COVID-19 vaccine
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China National Biotec Group Company Limited
Care-resistant Behavior, Dementia
Reducing Care-Resistant Behaviors During Oral Hygiene in Persons With Dementia
The main purpose of this study is to test a method of providing mouth care to persons with dementia who live in nursing homes. The method of providing mouth care is designed to reduce fear in persons with dementia, so that these…
- Trial name
- NCT01363258
- Testing
- Care-resistant mouth care (MOUTh), Evidence-based mouth care
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Intelligent Video Surveillance, Fall
Superiority of Intelligent Video Surveillance + Telealarm Over Telealarm Alone in Elderly People at Risk of Falling
Maintaining the elderly at home and preventing them from falling are major public health issues. The vast majority of elderly people wish to remain at home.
- Conditions
- Intelligent Video Surveillance, Fall, Home, Frail Elderly Person
- Trial name
- VIGIALARM (NCT05875038)
- Testing
- video system, Tele-alarm
- Where
- France
- Volunteers
- 395 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Muscle Weakness
Promoting Seniors' Health With Home Care Aides
This study aims to test whether a safe physical activity program with a built-in motivational enhancement component, performed in a seated position, preserves the function and well-being of older home care clients.
- Trial name
- NCT03301116
- Testing
- Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Illinois Chicago
Healthy Aged Volunteers
The Influence of Different Types of Physical Exercise on Immunosenescence in Elderly Persons
This study aims to identify the mechanisms by which physical exercise can counter inflammation and improve immune function in older persons.
- Trial name
- NCT04534049
- Testing
- Intensive Strength Training (IST), Strength Endurance Training (SET), Flexibility Training (FT)
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Geriatric, Exercise Adherence
Adherence for Exercise Rehabilitation in Older People Trial
Exercise is an effective treatment modality for many chronic conditions. The effectiveness of prescribed exercise can be limited by adherence to exercise programmes.
- Trial name
- AERO (NCT03643432)
- Testing
- Exercise adherence intervention, Usual Care
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Oxford University Hospitals NHS Trust
Depressive Symptoms
Social Worker-led Mindfulness-based Intervention for Older People
Preliminary findings from a previous study conducted by the investigators suggest that a task-shared approach with modified mindfulness-based cognitive therapy (MBCT) supported by social workers is beneficial in managing…
- Trial name
- NCT06528132
- Testing
- Mindfulness-based intervention (MBI) (enhanced with peer supporters), Experimental: social worker-led MBI (without peer supporters)
- Where
- 13 sites in Hong Kong
- Volunteers
- 207 people
- Sponsor
- The University of Hong Kong
Feasibility of a Technology-based System in Aged Person
Feasibility Study of i-ACT in Aged Persons
A mix-method cross-sectional feasibility study performed in five aged care institutes in Flanders, Belgium. A convenience sample of 48 aged persons was recruited and 12 supervisors (i.e.
- Trial name
- i-ACT-aged (NCT04489563)
- Testing
- i-ACT
- Where
- 5 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- PXL University College
Activities, Daily Living, Cognitive Function
Montessori-Based Interventions for Older Adults
The aim of this study is to evaluate the effect of Montessori-based interventions on cognitive function and activities of daily living in older adults.
- Trial name
- NCT07758478
- Testing
- Montessori
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Executive Functions
Effects of Modern Board Games on Well Being in Older Adults
The aim of the study is to assess the effects of an intervention using modern board game-based learning in a sample of older individuals.
- Trial name
- JUMEMO3e+ (NCT06306365)
- Testing
- Modern board game-based learning
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Smart Community- and Home-based Integrated Care Services
Effectiveness of a Smart Community- and Home-based Integrated Care Services System for Elderly People
In recent years, the widespread application of emerging information technologies such as artificial intelligence, the Internet of Things, big data, cloud computing, and 5G has made "smart " a new breakthrough in the integrated…
- Trial name
- ESCHIC (NCT06848036)
- Testing
- smart integrated care services
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liu Zhihan
Mental Health Issue, Emotional Stress
DISCOVER Workshop Programme for Care Experienced Young People
The NHS DISCOVER team has secured 2-year funding from the Maudsley Charity to tailor the workshop programme the investigators deliver in school Sixth Forms to meet the specific needs of Care Experienced young people.
- Conditions
- Mental Health Issue, Emotional Stress, Emotional Regulation
- Trial name
- NCT05220436
- Testing
- DISCOVER workshop programme
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- South London and Maudsley NHS Foundation Trust
Unresectable Colorectal Cancer, Advanced Malignancy
Clinical Efficacy of Transarterial Chemoembolization in Elderly Patients With Advanced Unresectable Colorectal Cancer
We plan to conduct a prospective, two-arm, open-label phase Ⅱ study to evaluate whether transarterial chemoembolization with FOLFOX plus/minus intravenous cetuximab/bevacizumab significantly improves the efficacy and safety…
- Conditions
- Unresectable Colorectal Cancer, Advanced Malignancy, Elderly (People Aged 65 or More)
- Trial name
- NCT07209384
- Testing
- Transarterial chemoembolization
- Volunteers
- 50 people
- Sponsor
- Junpeng Wang
Accidental Fall, Quality of Life
Safe and Well Visits by the Fire and Rescue Service to Prevent Falls and Improve Quality of Life in Older People
FIREFLI is a large, pragmatic, individually randomised, controlled trial with embedded economic and qualitative evaluations. The aim of the research is to see whether Safe and Well Visits delivered by the Fire and Rescue Service…
- Conditions
- Accidental Fall, Quality of Life, Aged
- Trial name
- FIREFLI (NCT04717258)
- Testing
- Fire and Rescue Service Safe and Well Visit, Self-Determination Theory informed trial invitation letter, Pen included with reminder questionaire
- Where
- 2 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Caroline Fairhurst
Cognitive Impairment, Cognitive Decline
Multicentre Study About the Effect of Individual Reminiscence Therapy
This study aims to evaluate the effect of individual reminiscence therapy (RT) on the global cognitive function of people with neurocognitive disorders attending social responses and to evaluate the ability of individually…
- Conditions
- Cognitive Impairment, Cognitive Decline, Dementia, Neurocognitive Disorders
- Trial name
- NCT04047238
- Testing
- Reminiscence Therapy
- Where
- 25 sites in Portugal
- Volunteers
- 251 people
- Sponsor
- Rsocialform - Geriatria, Lda
Heart Failure
A Comparison of Magnetic Resonance Imaging in Persons With Heart Failure to Health, Aged Matched Controls
The purpose of this study is to examine the relation between the structural brain changes associated with heart failure, neurocognitive performance, and how these changes impact self-care behaviors.
- Trial name
- MIND-HF (NCT02572648)
- Testing
- Brain Imaging (Neuroimaging), Cognitive Function Assessment
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Emory University
Dynapenia, Abdominal Obesity
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life.
- Trial name
- NCT07180485
- Testing
- whole body vibration training, control group
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
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