Clinical trials: Elderly Persons
Neurocognitive Disorders, Dementia
Cognitive Stimulation in the Elderly: Individual Intervention on Cognitive Frailty
Cognitive Stimulation (CS) in the elderly, as a group intervention, shows benefits on the cognition and quality of life of people with neurocognitive disorder (NCD)(ie, dementia).
- Trial name
- ECOG_CS (NCT03514095)
- Testing
- Individual Cognitive Stimulation Therapy Program
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- Escola Superior de Enfermagem de Coimbra
Subjective Cognitive Decline (SCD), Olfactory Dysfunction
The Efficacy of Modified Olfactory Training for MCI High-Risk Individuals
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can delay the progression of MCI in older…
- Conditions
- Subjective Cognitive Decline (SCD), Olfactory Dysfunction, Mild Cognitive Impairment (MCI), ELDERLY PEOPLE
- Trial name
- NCT06821828
- Testing
- Modified olfactory training device, Conventional olfactory training device
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Peking University Third Hospital
Elderly People Hospitalized
Prospective Study on Appetite Stimulation by Culinary Scents in the Elderly People
Undernutrition affects 2 million people in France, including 400,000 elderly people living at home and 270,000 in nursing homes. It leads to increased morbidity, dependency and mortality.
- Trial name
- APPETIT-SENS (NCT06530628)
- Testing
- Adult patients resident in Pavillon C of the Pierre Garraud Hospital
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
Alzheimer's Disease
Group Therapy for Caregivers of Alzheimer's Disease Patients in Spanish Elderly Persons Centres
An experimental study designed to test the effectiveness of a psychological intervention based on group therapy for the caregivers of Alzheimer's disease patients.
- Trial name
- cuiDem (NCT02418806)
- Testing
- Psychotherapy groups, Self-help groups
- Where
- 11 sites in Spain
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Frail Elderly Syndrome
HOPE (Healthy Older People Everyday) To Age in Place
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment, falls in older adults carry an increased risk for poor health outcomes and if identified early, can be prevented…
- Trial name
- NCT03797352
- Testing
- Multicomponent exercise
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Sarcopenia, Obesity
The Effectiveness of Lifestyle Intervention on Body Composition, Physical Performances and Quality of Life Among Elderly People in Long-term Care Facilities
Purpose: To understand the change in body composition, physical functions and quality of life of elderly residents with sarcopenic obesity in LTC facilities after the implementation of exercise intervention.
- Trial name
- NCT02912338
- Testing
- Resistant Training, Control Group
- Volunteers
- 123 people
- Sponsor
- Central Taiwan University of Science and Technology
Transcranial Direct Current Stimulation, Transcranial Alternating Current Stimulation
Cognitive Enhancement in Healthy Elderly People
According to the European Commission Special Report, till 2030 it is expected ca. 40% increase of population aged 66-79. Increasing population of elderly people in modern society has suggested that more individuals are expected…
- Trial name
- Pro-Cog (NCT04997226)
- Testing
- tDCS or tACS over the left DLPFC with adaptive memory game
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Cognitive Impairment, Depression
The Efficacy of Omega-3 Fatty Acids in Maintaining Optimal Mental Health in Elderly People
The efficacy of EPA-DHA supplementation will be assessed in a randomized placebo-controlled trial with cognitive decline and early signs of depression as primary outcome measures.
- Trial name
- NCT00124852
- Testing
- n-3 Fatty Acid Supplementation
- Where
- Netherlands
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- ZonMw: The Netherlands Organisation for Health Research and Development
Fall, Fall Accident
Village Doctor-Delivered Fall Prevention Program for Older Adults in Rural Chongqing
Falls are a leading cause of injury among older adults in rural China. This study evaluated whether a village doctor-delivered fall prevention program, integrated into the national Basic Public Health Services, could reduce falls…
- Trial name
- NCT07898878
- Testing
- Multicomponent fall prevention program, Usual Care
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Chongqing Center for Disease Control and Prevention
Elderly Person
Emotional Suppression in Elderly Individuals
The world's population is aging, and the proportion of individuals aged 60 and over is rapidly increasing. With aging, the prevalence of both physical and psychological health problems increases, negatively impacting quality of…
- Trial name
- NCT07122817
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Istinye University
Post-acute COVID-19 Syndrome
The Study of Brave-LC LDN Treatment Trial
This is a randomized, double-blind, placebo-controlled Phase 3 trial evaluating the efficacy and safety of a 16-week course of low-dose naltrexone (LDN) in approximately 1,300 participants aged 6 to 25 years with fatigue…
- Trial name
- NCT07916259
- Testing
- naltrexone
- Where
- 13 sites in United States
- Volunteers
- 1,300 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Frailty, Frailty Syndrome
Maintaining and imPrOving the intrinSIc capaciTy Involving Primary Care and caregiVErs
The POSITIVE platform offers the possibility of unsupervised monitoring of pre-frailty and frailty status in a community setting, to detect the onset of frailty and to assess its evolution.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- POSITIVE (NCT04592146)
- Testing
- Frailty multicomponent intervention supported by POSITIVE, Frailty multicomponent intervention
- Where
- 3 sites in Poland, Spain and 1 more
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario Getafe
COVID-19
Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19
The purpose of this study is to evaluate the safety and immunogenicity of a single dose of Sanofi's Omicron subvariant-based Nuvaxovid in participants ≥ 65 years of age and participants 12 through 64 years of age who have at…
- Trial name
- NCT07861542
- Testing
- Omicron Subvariant-Based SARS-CoV-2 Recombinant Spike Vaccine Adjuvanted With Matrix-M
- Where
- 20 sites in United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Sanofi
Sarcopenia
Muscle Assessment Through Ultrasound in the Evaluation of Acute Sarcopenia
Traditionally, muscle mass - a part of the concept of sarcopenia - is measured by computed tomography (CT) or dual-energy X-ray absorptiometry (DEXA) scan.
- Trial name
- NCT03740061
- Testing
- Ultrasonographic assessment of muscle
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universiteit Antwerpen
Frailty Syndrome, Frail Elderly Syndrome
Effectiveness of a Multimodal Intervention on Function in Older Frail People With Diabetes in Latinamerican
Randomized clinical trial, international, multicentre, single-blind, two parallel groups, pragmatic. It will be carried out by investigators in several Latin American countries (Chile, Colombia, Mexico and Peru) and with random…
- Conditions
- Frailty Syndrome, Frail Elderly Syndrome, Diabetes Mellitus, Type 2
- Trial name
- DIABFRAIL (NCT04504968)
- Testing
- Multimodal intervention, Usual care group
- Where
- Colombia
- Volunteers
- 713 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Long COVID
Exercise for Health in Patients With Post-acute Sequelae of COVID-19
Background: Many patients with COVID-19 present the so-called post-acute sequelae of COVID-19 such as fatigue, post-stress discomfort, dyspnea, headache, pain mental impairment, incapacity to perform daily physical tasks ant…
- Trial name
- EJerSA-COVID (NCT05848518)
- Testing
- Rehabilitation program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Campus docent Sant Joan de Déu-Universitat de Barcelona
Physical Activity and Wellbeing, Whole Health
Online Mindfulness-based Dance/Movement Therapy on Physical Activity and Whole-Person Health in Older Adults
This randomized controlled trial will examine whether an online, group-based Mindfulness-based Dance/Movement Therapy (M-DMT) intervention can increase physical activity and improve whole-person health among sedentary older…
- Trial name
- MOVE WELL (NCT07852572)
- Testing
- Mindfulness-based Dance/Movement Therapy, Stony Brook Health Education Program (HEP)
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Drexel University
Nutritive Value
Nutritional Intake of "Finger-food" on Elderly People in Seniors's Resident
The undernourishment and the prevention of its risk at the elderly person in seniors's resident represent a major issue in public health.
- Trial name
- FIFO (NCT02925728)
- Testing
- Finger-Food, Without Finger-Food
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Quality of Life, Cognitive Impairment
Effect of the Mindfulness-Based Health Promotion Program (MBHP) in the Elderly: a RCT
According to the World Health Organization (WHO), it is estimated that by 2025 the number of older people in Brazil will be approximately 33.4 million and it will be the sixth population in absolute numbers of the elderly in the…
- Conditions
- Quality of Life, Cognitive Impairment, Psychological
- Trial name
- NCT03706807
- Testing
- Mindfulness-Based Intervention, Cognitive Stimulation
- Where
- Brazil
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Centro Mente Aberta de Mindfulness
Hyperthermia, Heat; Weather
Protective Cooling Measures to Safeguard Elderly People From Dangerous Summer Heat
With the increasing incidence and severity of extreme heat events accompanying climate change, there is an urgent need for sustainable cooling strategies to protect heat-vulnerable older adults, who are at increased risk of…
- Conditions
- Hyperthermia, Heat; Weather, Aging, Type2 Diabetes
- Trial name
- NCT05274009
- Testing
- No cooling (control), Recommended cooling, Hybrid cooling
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
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