Clinical trials: Elderly Persons
Readmission, Readmission Rates
A Clinician-Patient Dual Behavior Change Framework to Leverage Informed Digital Nudges to Reduce Hospital Readmissions and Improve Patient Outcomes: A Trial for Scalable Strategy to Reduce Readmissions (PREVENT-R)
The PREVENT-R trial will evaluate an intervention targeting both clinician and patient behavior. The clinician-focused piece consists of an electronic medical record-based digital nudge presented to emergency department…
- Conditions
- Readmission, Readmission Rates, Readmission, Hospital, Elderly (People Aged 65 or More)
- Trial name
- PREVENT-R (NCT07890961)
- Testing
- Digital nudge prompting
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Yale University
Mobility Limitation, Physical Activity
PREPA PREvention of Loss of Autonomy
According to several reports, the proportion of people aged 80yrs or older will be doubled within the next 25y, reaching 10% of the global population.
- Trial name
- PREPA (NCT03667664)
- Testing
- Multidimensional assessments, Multicomponent group-based and supervised exercise program, Follow-up at T3 + 6 months and T3 + 12 months
- Where
- France
- Volunteers
- 530 people
- Sponsor
- Hospices Civils de Lyon
Influenza
Clinical Study of the Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in People Aged 65 Years or Older
This clinical trial aims to study the immunogenicity of GSK Biologicals' influenza vaccine GSK2186877A in people aged 65 years or older.
- Trial name
- NCT00765076
- Testing
- GSK Biologicals' influenza vaccine GSK2186877A, GSK Biologicals' Fluarix
- Where
- 4 sites in United States, Spain
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Covid-19
RT-PCR SARS-CoV-2 at 1 Month of COVID-19 Infection in the Geriatric Population
Evaluation of the rate of positive RT-PCR SARS-CoV-2 test at 1 month of COVID infection among elderly people. It is unclear how long an individual with COVID-19 will remain "sick" and "contagious".
- Trial name
- COVID-19GAOM (NCT04427358)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Drug Usage
Cooperation for Improved Pharmacotherapy in Home-dwelling Elderly People Receiving Polypharmacy - The COOP Study
Polypharmacy increases the risk of adverse drug effects, interactions and other drug-related problems, and several studies indicate that inappropriate drug use is a major reason for poor health and impaired function in the…
- Trial name
- COOP (NCT02379455)
- Testing
- Comprehensive drug review
- Where
- Norway
- Volunteers
- 192 people
- Sponsor
- Oslo University Hospital
Alzheimer Disease or Associated Disorder
Evaluation of the Effects of Serious Cognitive Games on a Digital Tactile Table for Elderly People with Alzheimer's Disease or Related Disorders
Alzheimer's disease and related disorders are chronic, progressive diseases that have a major impact on the lives of sufferers and their families.
- Trial name
- NCT06781645
- Testing
- The system involves a digital table with a tactile and interactive surface, providing several play areas. It simulates a village and offers different types of serious cognitive games: semantic memory
- Volunteers
- 46 people
- Sponsor
- RIVAGES
Aging, Sarcopenia
Effect of Immunocal® With Exercise Versus Casein With Exercise on Aging Processes in Elderly Persons
Aging is typically associated with a decrease in skeletal muscle mass and muscle function, which contributes decisively to disability in old age and to the loss of quality of life.Resistance exercise can increase muscle strength…
- Trial name
- NCT00935610
- Testing
- Immunocal, Casein
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Immunotec Inc.
Cardiovascular Diseases, Inflammation
Dietary Intake of Alpha-linolenic Acid in Elderly
The purpose of this study is to evaluate the antiatherogenic and anti-inflammatory potential of an adequate intake of alpha-linolenic acid in elderly.
- Conditions
- Cardiovascular Diseases, Inflammation, Metabolism Disorder, Lipid
- Trial name
- NCT03025620
- Testing
- Rapeseed oil, Sunflower oil
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
FRAILTY
FRED Exergame Including Biofeeback Supervision
A pilot six-week randomised controlled trial was carried out introducing biofeedback with physiological constants as follows: systolic blood pressure, diastolic blood pressure, heart rate and blood oxygen saturation in the…
- Trial name
- NCT03425227
- Testing
- FRED EXERGAME
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Begoña Garcia Zapirain
Individual Difference, Food Sensitivity
Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Brief Summary: This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04302779
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Reading
Accidental Falls, Frailty
Elderly Falls Prevention With sLiFE Program in Primary Care
This study aims to guide older people living in the community on appropriate strategies within a fall prevention program. This program is aimed at training in daily activities carried out through group workshops (guided by a…
- Conditions
- Accidental Falls, Frailty, Elderly, Activities, Motor
- Trial name
- NCT05912088
- Testing
- Intervention Group, Control Group
- Where
- Spain
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Under-consumption of Food
Engaging Elderly People Living in Institutions in Eating Situations
Several recent studies have revealed a significant under-consumption of food in hospitals and nursing homes. For instance, at the Dijon University Hospital, 8 out of 10 patients consume less than 80% of the meals served.
- Trial name
- ENGAGE (NCT05239442)
- Testing
- Taste Commission, Evaluation of the taste commissions, Entretien SWOT
- Where
- France
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Mobility
Best Function of Range of Motion (cRCT)
Mobility is a crucial factor for independence and quality of life in older people. However, the majority of those in retirement homes are not physically active to maintain mobility and independence.
- Trial name
- bestform (NCT04207307)
- Testing
- Multimodal exercise program, Usual Care
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Dental Plaque, Bleeding of Subgingival Space
Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons
On average, the dental condition of elderly people is poor due to various reasons. The importance of oral health maintenance of the ageing population has been recognized by the World Health Organization (WHO), as oral health…
- Conditions
- Dental Plaque, Bleeding of Subgingival Space, Oral Complication
- Trial name
- NCT06576063
- Testing
- Lumoral Treatment, Standard oral hygiene methods
- Where
- 3 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Acute Pneumonia, Elderly Person
Aspirin in Acute Pneumonia in the Elderly: a Multicenter, Double-blind, Randomized, Placebo-controlled Trial.
Acute pneumonia is a very common disease, and one of the leading causes of hospitalization and death in France. Almost a century after the discovery of penicillin, no major breakthrough has significantly reduced pneumonia-related…
- Trial name
- ASPAPY (NCT06774846)
- Testing
- Acetylsalicylic acid/Aspirin (100 mg)
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Frail Elderly Syndrome, Sarcopenia
Physical Fitness, Body Composition and Frailty in Elderly People.Exercise Program Effecsts. EXERNET Elder 3.0
One of the major changes occurring in developed societies is a significant ageing of the population. Nowadays, because of an enhanced life expectancy, 17% of the Spanish population is composed of people over 65 and the number is…
- Conditions
- Frail Elderly Syndrome, Sarcopenia, Physical Activity
- Trial name
- EXERNETElder (NCT03831841)
- Testing
- Multicomponent exercise programe
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Dementia, Cognitive Impairment
Effect of Circadian Light on Hospitalized Persons With Dementia and Older Adults With Cognitive Impairments.
Light stimulates the human visual system and the biological functions in the retina, also referred to as non-visual responses, e.g. hormone production.
- Trial name
- NCT05535790
- Testing
- Naturalistic LED light, Standard/traditional lighting
- Volunteers
- 80 people
- Sponsor
- Zealand University Hospital
Cognitive Impairment
The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study
Older adults with type 2 diabetes experience cognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (based on body mass, glucose levels) are at higher…
- Trial name
- NCT03254381
- Testing
- Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Western University, Canada
Chronic Disease, Chronic Pain (Back / Neck)
Nature-based Intervention for Chronic Pain in Older People
The goal of this clinical trial is to learn if a nature-based intervention program has positive effects on the physical and psychosocial health in a group of older participants with chronic non-specific lower back pain.
- Conditions
- Chronic Disease, Chronic Pain (Back / Neck), Older Adults (65 Years and Older)
- Trial name
- PARC-2 (NCT07002853)
- Testing
- Nature-based Intervention
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Université du Québec à Chicoutimi
Dysphagia
How Active Breathing Training Improves Dysphagia in Elderly People
The goal of this clinical trial is to explore the impact of Active Breathing Exercises on swallowing function and quality of life in community-dwelling elderly individuals (≥60 year old) with swallowing disorders.
- Trial name
- NCT06303856
- Testing
- Active Breathing Exercises
- Volunteers
- 300 people
- Sponsor
- Muhammad
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