Clinical trials: Elderly Persons
Muscle Fiber Atrophy, Type II
The Effect of Neuromuscular Electrical Stimulation (NMES)
The purpose of this project is to test the effectiveness of neuromuscular electrical stimulation (NMES) that produces 40 % of maximum voluntary contraction (MVC) in increasing muscle size and improvement in muscle force output…
- Trial name
- NMES (NCT00765739)
- Testing
- Neuromuscular electrical stimulation, voluntary strengthening exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Elderly
Chronic Effects of Exercise on Motor Memory Consolidation in Elderly People
The main purpose of this study was to investigate if a six months period of physical exercise could improve motor memory consolidation in elderly people.
- Trial name
- NCT02731261
- Testing
- Motor memory consolidation
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Castelo Branco
Dementia
Study on the Efficacy of Speed-Feedback Therapy for Elderly People With Dementia
The purpose of this study is to verify the efficacy of speed-feedback therapy in improving the cognitive function of elderly people with dementia by a randomized controlled trial, and to demonstrate how that affects ADL and QOL.
- Trial name
- NCT00450047
- Testing
- Speed-feedback therapy system with a bicycle ergometer, Ergometer at conventional settings
- Volunteers
- 120 people
- Sponsor
- Hiroshima University
Dementia, Falls
A Study of Why People With Early Memory Problems Fall or Almost Fall
The purpose of this study is to identify the factors that are associated with falls and near falls in community-dwelling older adults with early-stage dementia.
- Conditions
- Dementia, Falls, Near-Falls
- Trial name
- NCT00434889
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Pneumonia With Hospitalized Elderly Patient
Interest of Ascorbic Acid in the Management of Pneumonia in Elderly People Hospitalized.
Pneumonia is the second common infection and its risk increases for elderly. In this population, it is the first cause of mortality by infections, and source of many complications.
- Trial name
- PNEUMO-VITA-C (NCT02186158)
- Testing
- Vitamin C
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Bordeaux
Depressive Symptoms, Ageism
Cultural Arts Programme for Older Chinese
This study examines the effectiveness of an innovative cultural arts program in reducing depressive symptoms and age-related self-stigma among older Chinese as compared to service as usual through a randomized waitlist controlled…
- Conditions
- Depressive Symptoms, Ageism, Older Adults, Psychosocial Intervention
- Trial name
- NCT06527625
- Testing
- Cultural Arts Program, Treatment as usual
- Where
- Hong Kong
- Volunteers
- 63 people
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment (MCI)
Cognitive-motor Training in Community-dwelling Older People With Mild Cognitive Impairment
As the global population ages, the prevalence of mild cognitive impairment (MCI) among older adults, which ranges from 5% to 40%, is expected to rise.
- Trial name
- NCT07241598
- Testing
- Smart±step cognitive-motor training
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
Elderly Person
Gardening Activities for the Elderly Psychological Well-Being and Depression
Purpose of the Study: This research will be conducted to determine the effects of gardening activities applied to the elderly in nursing homes on psychological well-being and depression.
- Trial name
- NCT05256680
- Testing
- Gardening Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ordu University
Older Adults (50-90 Years), Depression
Integrating Depression Care Into HIV Services for Older People With HIV Using a Stepped Care, Task-Sharing Approach.
Depression levels will be compared using PHQ-9 in the Treatment as Usual arm(TAU) VS intervention arm to see if the stepped care intervention is effective in treating depression.
- Trial name
- NCT06894680
- Testing
- Stepped care, Treatment as usual
- Where
- Nigeria
- Volunteers
- 100 people
- Sponsor
- Royal Society of Tropical Medicine and Hygiene
Elderly People, Food Intake Measurement
Validity, Reliability and Feasibility of an Automated Photographic Measurement/Assessment of Food Intake in the Hospitalized Elderly
Malnutrition affects 50% to 70% of hospitalized elderly people, and is all the more worrying in the elderly because of its clinical impact.
- Trial name
- PAMPILLE (NCT03650686)
- Testing
- Food weighing (gold standard), Automated photographic method (method to be evaluated), Semi-quantitative method (routine method)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Breast Cancer
TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called ARV-471) when given together with other medicines for the potential treatment of advanced or metastatic breast cancer.
- Trial name
- NCT05548127
- Testing
- ARV-471, Abemaciclib
- Where
- 37 sites in United States, Canada and 2 more
- Volunteers
- 37 people
- Sponsor
- Pfizer
Age-Related Memory Disorders
Effectiveness of a Cognitive Training Program (UMAM Method) in Elderly People Without Dementia
The study is oriented to analyze the effectiveness of a cognitive training method (UMAM) on cognitive functions, subjective memory and mood state in elderly people without dementia.
- Trial name
- NCT04245579
- Testing
- Multifactorial Memory Training Program (UMAM method)
- Where
- Spain
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Madrid Salud
Elderly Patients With a Solid Tumor
Are the Fried Criteria Predictive of a Functional Decline in Older People With Solid Malignant Tumors?
Identifying the frail elderly patients or those at risk of becoming frail has become a cornerstone of modern geriatric medicine. Many instruments have been developed to identify fragility at the individual level.
- Trial name
- NCT02662179
- Testing
- Quality of life evaluation, Functional decline assessment, Physical decline assessment
- Where
- 2 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Brugmann University Hospital
Prescriptions, Elderly (people Aged 65 or More)
Inappropriate Prescribing in the Elderly
The management of pharmacotherapy in elderly patients is an increasingly critical aspect, as polypharmacy, combined with the pharmacokinetic and pharmacodynamic changes typical of aging, makes older adults more sensitive to the…
- Conditions
- Prescriptions, Elderly (people Aged 65 or More), Hospitalized, Prevalence
- Trial name
- STOPP&START (NCT06760728)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
Frail Elderly People
Frail Elderly Subjects - Evaluation and Follow-Up
This was a prospective multicenter cohort study of elderly people admitted to medical wards via emergency departments. Subjects were followed up to 36 months.
- Trial name
- SAFES Cohort (NCT02834728)
- Testing
- telephone interview
- Where
- France
- Volunteers
- 1,306 people
- Sponsor
- CHU de Reims
Elderly People
Study of the Cutaneous Microcirculation in Elderly People
Pressure ulcers are a common and frustrating problem and their treatment is critical in elderly people. The interaction between external pressure and the skin vascular is central to the prevention of pressure ulcers.
- Trial name
- NCT00266071
- Testing
- Cutaneous response
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Tuberculosis
Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old.
This is a randomized, blind, positive-controlled study to explore the skin test dosage of recombinant mycobacterium tuberculosis fusion protein ( EEC) in the population aged 18 to 65 years old , and to further evaluate the safety…
- Trial name
- NCT06305104
- Testing
- 2.5μg/ml EEC, 5μg/ml EEC, 5 unit（U） EC
- Where
- 6 sites in China
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Chengdu CoenBiotech Co., Ltd
Executive Dysfunction, Mild Cognitive Impairment (MCI)
Feasibility Study of Mixed Reality Exergame on Performance and Cortical Outcomes
The executive dysfunctions are a problem in individuals with MCI which predict conversion to dementia and is positively related to physical activity level.
- Trial name
- NCT06843733
- Testing
- Mixed reality exergame, Education
- Where
- Thailand
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hematological Cancers, Frailty
Improving Quality of Life in Frail, Older Patients with Hematological Cancer Through Geriatric Assessment and Treatment - a Pilot Study
Purpose of the Study This study aims to assess the feasibility of conducting outpatient geriatric health assessment (comprehensive geriatric assessment - CGA) alongside initiation of hematological cancer treatment in frail older…
- Conditions
- Hematological Cancers, Frailty, ELDERLY PEOPLE
- Trial name
- IMPROVE pilot (NCT06689332)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Odense University Hospital
Depressive Symptoms
Social Worker-led Mindfulness-based Intervention for Older People
Preliminary findings from a previous study conducted by the investigators suggest that a task-shared approach with modified mindfulness-based cognitive therapy (MBCT) supported by social workers is beneficial in managing…
- Trial name
- NCT06528132
- Testing
- Mindfulness-based intervention (MBI) (enhanced with peer supporters), Experimental: social worker-led MBI (without peer supporters)
- Where
- 13 sites in Hong Kong
- Volunteers
- 207 people
- Sponsor
- The University of Hong Kong
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