Clinical trials: Elderly Persons
Individuals Over 65 Years of Age
Breath Meditation on the Older People
A decrease in physical activity during old age leads to a decline in quality of life and life satisfaction. Increased stress and anxiety levels during this period negatively affect individuals' mood and reduce their quality of…
- Trial name
- MEDITATION (NCT07263828)
- Testing
- breathing meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Critical Illness, Geriatric Assessment
Geriatric Assessment at Discharge From the Intensive Care Unit in Patients Aged 75 Years and Older: a Feasibility Study
The number of patients aged over 75 continues to grow, and, according to INSEE, will represent almost 10% of the French population in 2021, an increase of 2.4 points since 2000.
- Conditions
- Critical Illness, Geriatric Assessment, Older People, Frailty
- Trial name
- PreGEDI (NCT06513130)
- Testing
- Geriatric assessment in the 7 days following ICU discharge., No geriatric assessment in the 7 days following ICU discharge.
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
HIV-1-infection, CD4+ T Lymphocytopenia
Pyridostigmine as Immunomodulator in People Living With HIV
Human immunodeficiency virus (HIV) infection is characterized by persistent immune activation and a constant turnover of T cells. This leads to a precipitous fall in the number of T cells, as well as to an early immunosenescence.
- Conditions
- HIV-1-infection, CD4+ T Lymphocytopenia, Immune Deficiency, Immuno-senescence
- Trial name
- NCT03312244
- Testing
- Pyridostigmine Bromide
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Non-muscular Invasive Bladder Cancer
BCG for Therapeutic Use Phase I Clinical Trial
This clinical study adopted a single-arm, open, single-centertrial design. The purpose of this study was to evaluate the safety and tolerability, PK characteristics, shedding and immune response characteristics of BCG for…
- Trial name
- NCT06100653
- Testing
- BCG for therapeutic use
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Chronic Obstructive Pulmonary Disease
Evaluation in Individuals with COPD and Asymptomatic Individuals
The literature does not provide sufficient information on the evaluation of frailty, handgrip strength, physical activity, kinesiophobia, and fatigue in elderly individuals with Chronic Obstructive Pulmonary Disease and…
- Trial name
- NCT06077357
- Testing
- MMSE Test, PASE Test, The PRISMA-7 Frailty Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Healthy Elderly
A Study In Healthy Elderly People To Evaluate Safety, Toleration, Pharmacokinetics and Pharmacodynamics of Multiple Oral Doses Of PF-06743649
The purpose of this study in healthy elderly people is to evaluate safety, toleration and time course of plasma concentration of multiple oral doses of PF-06743649- The pharmacodynamic activity of PF-06743649 will also be…
- Trial name
- NCT02170012
- Testing
- PF-06743649
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Aging
European Project on Nutrition in Elderly People
NU-AGE is a large multidisciplinary consortium (31 partners, from 17 EU countries) involving nutritionists, bio-gerontologists, immunologists and molecular biologists from the most prestigious institutions in Europe, 5 large food…
- Trial name
- NU-AGE (NCT01754012)
- Testing
- Dietary Intervention
- Where
- 5 sites in France, Italy and 3 more
- Volunteers
- 1,190 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Fall Prevention, Falls (Accidents) in Old Age
Validation of the Self-Assessment for Falls in the Elderly (SAFE) Questionnaire to Assess the Risk of Falls in People Aged 60 or Over.
This single-centre, cross-sectional diagnostic study will determine whether the new self-completed Self-Assessment for Falls in the Elderly (SAFE) questionnaire can classify fall-risk level (low, moderate, high) in adults ≥ 60…
- Trial name
- SAFE (NCT06961812)
- Testing
- Questionnaire and Physical Exam, Safe Self-Administered Questionnaire
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Nutritive Value
Nutritional Intake of "Finger-food" on Elderly People in Seniors's Resident
The undernourishment and the prevention of its risk at the elderly person in seniors's resident represent a major issue in public health.
- Trial name
- FIFO (NCT02925728)
- Testing
- Finger-Food, Without Finger-Food
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Centre Hospitalier Departemental Vendee
ELDERLY PEOPLE, Fall Prevention
Gamified Digital Balance Assessment for Older Adults in Community Settings: Development, Validation, and User Experience Evaluation in a Mixed Methods Study
The study was conducted in two sequential phases to evaluate the reliability and user experience of a GBDA tailored for community-dwelling older adults.
- Conditions
- ELDERLY PEOPLE, Fall Prevention, Digital Health
- Trial name
- NCT06958653
- Testing
- Brief-BESTest assessment, Digital balance assessment tool, Gamified Digital Balance Assessment (GDBA)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Parkinson's Disease (PD)
Characterising Physiological Resilience in People With Parkinson's Disease
Parkinson's disease (PD) is a condition that affects movement and gets worse over time. It is more common in older adults. People with PD may have symptoms like shaking, stiff muscles, slow movement, and trouble with balance.
- Trial name
- ParkEx (NCT07013513)
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Nottingham
Depressive Symptoms
Collaborative Stepped Care and Peer Support Programme for Older People At-Risk of or With Depression
To develop a viable and sustainable best practice model to promote elderly mental wellness and prevent elderly depression for Hong Kong, the Hong Kong Jockey Club Charities Trust has initiated a pilot holistic support project…
- Trial name
- JCJoyAge (NCT03593889)
- Testing
- Collaborative stepped care and peer support programme, Treatment as usual
- Where
- 8 sites in Hong Kong
- Volunteers
- 3,702 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Accidental Falls, Postural Balance
Feasibility of High-intensity Functional Exercise With Simultaneous Cognitive Challenge for Older People With Falls Risk
This study aims to evaluate the feasibility of a high-intensity functional exercise program with simultaneous cognitive challenge (HIFE+cog) among older people at risk of falls.
- Conditions
- Accidental Falls, Postural Balance, Gait, Cognition
- Trial name
- NCT06774508
- Testing
- HIFE+cog, HIFE
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Umeå University
HIV-1-infection
Study to Assess Switching to B/F/TAF in Treatment Experienced People With HIV Who Are at Least 65 Years of Age
To assess patient reported treatment satisfaction and medication tolerability in virologically suppressed HIV-1 infected adults who are at least 65 years of age who switch to a bictegravir/emtricitabine/tenofovir alafenamide…
- Trial name
- NCT05147740
- Testing
- B/F/TAF
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Tulika Singh, MD
Elderly
Chronic Effects of Exercise on Motor Memory Consolidation in Elderly People
The main purpose of this study was to investigate if a six months period of physical exercise could improve motor memory consolidation in elderly people.
- Trial name
- NCT02731261
- Testing
- Motor memory consolidation
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Castelo Branco
Elderly (People Aged 65 or More)
Acute Effects of Motor Imagery and Action Observation in the Elderly: Single-Blind Randomized Controlled Trial
The aim of this study is to investigate the effects of acute action observation, motor imagery, exercise, and combined exercise training on parameters such as balance, reaction time, flexibility, fear of falling, cognitive…
- Trial name
- NCT07016061
- Testing
- Motor İmagery Group, Action Observation Group, Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
ELDERLY PEOPLE
Laughter Yoga is Role in Enhancing Sleep and Well-being in the Elderly
Objective: The study aims to evaluate the effects of Laughter Yoga on sleep quality, vitality, active aging, and quality of life in individuals aged 60 and over.
- Trial name
- NCT06685731
- Testing
- Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Dementia, Femur Fracture
Care of Older People With Cognitive Impairment or Dementia Hospitalized in Traumatology Units
This is a quasi-experimental design with repeated observations, taken at baseline, post-intervention, and at one and three months post-intervention.
- Conditions
- Dementia, Femur Fracture, Continuity of Patient Care
- Trial name
- CARExDEM (NCT04048980)
- Testing
- CARExDEM
- Where
- Spain
- Volunteers
- 432 people
- Sponsor
- Hospital Clinic of Barcelona
Coronary Artery Disease, Elderly
Hybrid Group Singing
The overall objective of the planned future clinical trial is to test the investigator's central hypothesis that habitual singing over several weeks, similar to habitual exercise, will lead to sustained and favorable vascular…
- Trial name
- NCT07355192
- Testing
- group singing (hybrid format), instructional sing-along video series
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medical College of Wisconsin
Type 1 Diabetes
COVID-19 Pandemic Lockdown Effect in Adolescents and Young Adults With Type 1 Diabetes: Positive Results of an Unpreceded Challenge for Telemedicine and Patient Self-management
Lockdown resulting from the COVID-19 pandemic was an unpreceded model of the impact of lifestyle on chronic diseases, especially for adolescents and young adults with type 1 diabetes (T1D) whose lifestyle is known to strongly…
- Trial name
- COVIDIABADO (NCT04669912)
- Testing
- glucose control and sensor usage
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Sud Francilien
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