Clinical trials: Elderly Persons
Older Adults (50-90 Years), Mental Health
Project HOPEFUL: A PN-RCT With Implementation Science
This PN-RCT replicates and evaluates an 8-week warm calling treatment (i.e. caring contacts) delivered to older adults receiving home and community-based services (HCBS; classified as "homebound") in 20-30 minute call "dosages"…
- Conditions
- Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning
- Trial name
- NCT07475039
- Testing
- Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Florida
Dementia, Neurocognitive Disorders
Effect of Individual Cognitive Stimulation on Memory and Executive Function in Older Adults With Alzheimer's Disease
This multicentre study, with a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions, which provide care and supportive services for older adults diagnosed with mild or…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT05433493
- Testing
- Cognitive stimulation
- Where
- 14 sites in Portugal
- Volunteers
- 142 people
- Sponsor
- Rsocialform - Geriatria, Lda
Frail Elderly People
Continuum of Care for Frail Elderly People
The present study "Continuum of care for frail elderly people" form part of the research programme "Support for frail elderly persons - from prevention to palliation" (www.vardalinstitutet.net) which comprises research into three…
- Trial name
- NCT01260493
- Testing
- integrated health care chain
- Where
- Sweden
- Volunteers
- 181 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Accidental Fall, Quality of Life
Safe and Well Visits by the Fire and Rescue Service to Prevent Falls and Improve Quality of Life in Older People
FIREFLI is a large, pragmatic, individually randomised, controlled trial with embedded economic and qualitative evaluations. The aim of the research is to see whether Safe and Well Visits delivered by the Fire and Rescue Service…
- Conditions
- Accidental Fall, Quality of Life, Aged
- Trial name
- FIREFLI (NCT04717258)
- Testing
- Fire and Rescue Service Safe and Well Visit, Self-Determination Theory informed trial invitation letter, Pen included with reminder questionaire
- Where
- 2 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Caroline Fairhurst
Muscle Weakness
Promoting Seniors' Health With Home Care Aides
This study aims to test whether a safe physical activity program with a built-in motivational enhancement component, performed in a seated position, preserves the function and well-being of older home care clients.
- Trial name
- NCT03301116
- Testing
- Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Illinois Chicago
Removable Dental Prosthesis, Dental Restoration
Impact on General Functionality of an Immediate Prosthetic Functionalization Protocol in People Over 70 Years of Age With Deficient Removable Prostheses
Title: Evaluation of the impact on general functionality of the application of an immediate prosthetic functionalization protocol, in patients with deficient removable prostheses, compared with the conventional treatment that is…
- Conditions
- Removable Dental Prosthesis, Dental Restoration, Elderly, Functional Status
- Trial name
- NCT05595304
- Testing
- prosthetic refunctioning, conventional prosthetic treatment
- Where
- Chile
- Volunteers
- 108 people
- Sponsor
- Gerardo F Fasce Pineda, MD
Health Literacy, Middle Aged
Health Literacy-Based Multifactorial Program for Adults With Sarcopenia
Sarcopenia is a common age-related condition characterized by the progressive loss of muscle mass and function, which may lead to reduced physical performance, disability, and poorer quality of life.
- Conditions
- Health Literacy, Middle Aged, Elderly (People Aged 65 or More), Exercise Therapy
- Trial name
- NCT07654478
- Testing
- Multicomponent Intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Type 2 Diabetes, Chronic Disease
Prevention Strategies for Adolescents at Risk of Diabetes
The primary aim of PRE-STARt Phase 1 is to pragmatically evaluate and refine a risk assessment tool to identify those children with chronic disease risk factors (including Type 2 Diabetes).
- Trial name
- PRE-STARt (NCT02545140)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Diastolic Dysfunction
Effect of Exercise on Heart Function in Healthy Elderly People
The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years.
- Trial name
- NCT00804518
- Testing
- Aerobic interval training
- Where
- Norway
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Vitamin D Deficiency
Improving Functionality in Older People
The study will examine if overall functionality of older adults with Vitamin D insufficiency can be improved by optimal Vitamin D replacement over a period of approximately one year.
- Trial name
- NCT03611049
- Testing
- High dose Vitamin D3, Low dose Vitamin D3
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Old Age; Debility
Multicomponent Exercises in Functional Performance and Cognitive Ability of Hospitalized Elderly
Older patients spend most of their time in situations of muscle disuse during acute hospitalization. Physical inactivity is a key factor for the development of adverse events caused by hospitalization, known as iatrogenic…
- Trial name
- NCT05317338
- Testing
- Group-based exercise training during hospitalization
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Healthy
A Phase 1 Clinical Trial to Investigate the Safety, Tolerability, and Pharmacokinetics of AS-S603 in Healthy Participants
This trial is a randomized, double-blind, placebo-controlled, single- and multiple-oral administration, phase 1 clinical trial to investigate the safety, tolerability, and pharmacokinetics of AS-S603 in healthy Korean or…
- Trial name
- NCT06786676
- Testing
- AS-S603
- Where
- South Korea
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Amyloid Solution Inc
Hip Fractures
Tele-rehabilitation Intervention for People Post Hip Fracture - Randomized Controlled Trial (RCT)
Most surviving hip-fracture patients experience reduced mobility and lose their functional ability, which increases the risk of complications and rehospitalization.
- Trial name
- NCT03376750
- Testing
- CO - OP
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Herzog Hospital
Cardiovascular Health, Functional Health
Beetroot Extract and Quality of Life in Adults Aged 75 and Over
The increasing number of adults aged 75 years and older highlights the need for effective, low-cost interventions to preserve cardiovascular health, functional independence, and cognitive performance and to support healthy aging.
- Conditions
- Cardiovascular Health, Functional Health, Cognitive Function Decline, Physical Performance Decline in Older Adults
- Trial name
- BERS (NCT07666685)
- Testing
- Beetroot Extract Supplementation
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Older People
Cognitive Exergame Training on Dual-Task Cost and Balance Stability in Older Adults
Balance stability requires both motor and cognitive (mental) functions working together. Balance stability may decrease when performing two tasks at the same time (dual task), as cognitive and motor tasks compete for performing a…
- Trial name
- NCT05395676
- Testing
- Exergame home training programme
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Essential Hypertension
Evaluation of a Transmedial Psychoeducational Program to Improve Pharmacological Adherence
Population in Chile has experienced an accelerated process of demographic aging, which leads to changes in the composition of morbidity and mortality, with chronic noncommunicable diseases currently predominating.
- Trial name
- AFAM (NCT03924115)
- Testing
- Transmedial Psychoeducational Program to improve adherence full or partial (PS)
- Where
- Chile
- Volunteers
- 215 people
- Sponsor
- Universidad de Concepcion
COVID-19
Immunogenicity and Safety of Booster Immunization of COVID-19 Vaccine (Vero Cell), Inactivated (Omicron Variant) in Healthy People Aged 18 Years and Above
This is a randomized, double-blind, active-controlled Phase Ⅲ clinical trial, as well as an immuno-bridging clinical trial by parallel testing previous serum after primary immunization of COVID-19 vaccine (Vero cell), inactivated…
- Trial name
- NCT05381350
- Testing
- COVID-19 Vaccine (Vero cell), Inactivated (Omicron variant), COVID-19 Vaccine (Vero cell), Inactivated (CZ strain)
- Where
- China
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
Multimorbidity, Older Adults (65 Years and Older)
Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT
The goal of this clinical trial is to learn if I-CONNECT (Integrated Care for Older Adults with Major Depression and Physical Multimorbidity) can improve the health and well-being of older adults with depression or bipolar…
- Conditions
- Multimorbidity, Older Adults (65 Years and Older), Mood Disorders, Depression - Major Depressive Disorder
- Trial name
- I-CONNECT (NCT07211750)
- Testing
- integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidity in Leuven
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- KU Leuven
Obstructive Sleep Apnea, Sleep Apnea
Inflammation and Neurocognitive Damage Markers in Elderly People With Obstructive Sleep Apnea
The aging process tends to promote an overall increase in inflammation compromising the immunologic system regulation, sleep/wakefulness pattern, and neurocognitive performance.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Apnea, Obstructive, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT04882020
- Testing
- cortisol, BDNF, s100B, IL-1B, IL-6, IL-10, TNF-alpha
- Where
- Brazil
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Healthy, Elderly
Effects of Global Postural re-Education Program
The postural alterations present in the seniors people act as predisponent form of incapacities that provoke alterations in the quality of life.
- Trial name
- NCT00736762
- Testing
- GPR
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the State of Santa Catarina
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