Clinical trials: Elderly Persons
Meningococcal Meningitis, Serogroup B, Transgender Persons
Investigating Gender and Sex Differences in Immune Responses Through Vaccination of Transgender and Cisgender Persons
Sexual differences are a well-established source of biological variation in immune system functioning, with men often displaying lower adaptive immune responses (e.g.
- Conditions
- Meningococcal Meningitis, Serogroup B, Transgender Persons, Sex Differences in Immune Response, Vaccination
- Trial name
- Vaxxygender (NCT06832514)
- Testing
- Serogroup B meningococal vaccine
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Ghent
Drug Usage
Cooperation for Improved Pharmacotherapy in Home-dwelling Elderly People Receiving Polypharmacy - The COOP Study
Polypharmacy increases the risk of adverse drug effects, interactions and other drug-related problems, and several studies indicate that inappropriate drug use is a major reason for poor health and impaired function in the…
- Trial name
- COOP (NCT02379455)
- Testing
- Comprehensive drug review
- Where
- Norway
- Volunteers
- 192 people
- Sponsor
- Oslo University Hospital
Elderly (People Aged 65 or More), Quality of Life
Theory of Kolcaba on the Quality of Life and Psychological Well-Being Levels of the Aged People
A randomised controlled study will be conducted to determine the effect of nursing care based on Kolcaba's comfort theory on the quality of life and psychological well-being levels of the elderly.
- Conditions
- Elderly (People Aged 65 or More), Quality of Life, Psychological Well-being, Nurse
- Trial name
- NCT07050901
- Testing
- Nursing Care Based on Kolcaba's Comfort Theory
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Merve OZKAN
Frailty, Obesity
Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community
The goal of this observational study is to evaluate the relationship of gait speed with dynapenic or sarcopenic obesity in community-dwelling older people.
- Conditions
- Frailty, Obesity, Sarcopenia, Sarcopenic Obesity
- Trial name
- SGSF (NCT06413030)
- Testing
- 10 Meter Walk Test
- Where
- Chile
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Accidental Falls, Old Age; Debility
Interventions to Prevent Falls. PRECAISAL Study
This study aims to guide older people living in the community on appropriate strategies within a fall prevention program. This program is aimed at training in physical exercises carried out through group workshops or at…
- Conditions
- Accidental Falls, Old Age; Debility, Activity, Motor
- Trial name
- NCT05070533
- Testing
- Individual treatment, Groupal treatment
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Cognitive Decline, Subjective Cognitive Impairment
Effect of a Multidomain Intervention Plus Turmeric on the Prevention of Cognitive Decline in People Over 55 Years of Age With Insulin Resistance.
Introduction: The Insulin resistance itself has been recognized as an independent risk factor for dementia development. Insulin plays an important role in the regulation of muscle function and the processes of learning and…
- Conditions
- Cognitive Decline, Subjective Cognitive Impairment, Insulin Resistance
- Trial name
- NCT07284316
- Testing
- Turmeric extract
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Mexicano del Seguro Social
Immunosenescence
The Effect of Prebiotic B-GOS on the Immune Function, Metabolism and Gut Microbiota of Elderly People
The purpose of this study is to determine the effects of prebiotic B-GOS on the immune function, metabolism and gut microbiota of elderly people
- Trial name
- PRIMES (NCT01303484)
- Testing
- Bi2muno® GOS, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clasado
Mild Cognitive Impairment (MCI)
Cognitive-motor Training in Community-dwelling Older People With Mild Cognitive Impairment
As the global population ages, the prevalence of mild cognitive impairment (MCI) among older adults, which ranges from 5% to 40%, is expected to rise.
- Trial name
- NCT07241598
- Testing
- Smart±step cognitive-motor training
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
HIV, Aging
The Targeted Neurocognitive Training (TNT) Study
People with HIV (PWH) often suffer from cognitive impairments known as HIV-Associated Neurocognitive Disorder (HAND). Cognitive impairments in PWH are not fully captured by traditional neurocognitive assessment; thus, we must…
- Conditions
- HIV, Aging, Cognitive Function Abnormal, Cognitive Training
- Trial name
- TNT (NCT05773430)
- Testing
- Targeted Neurocognitive Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hematological Cancers, Frailty
Improving Quality of Life in Frail, Older Patients with Hematological Cancer Through Geriatric Assessment and Treatment - a Pilot Study
Purpose of the Study This study aims to assess the feasibility of conducting outpatient geriatric health assessment (comprehensive geriatric assessment - CGA) alongside initiation of hematological cancer treatment in frail older…
- Conditions
- Hematological Cancers, Frailty, ELDERLY PEOPLE
- Trial name
- IMPROVE pilot (NCT06689332)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Odense University Hospital
COVID-19
Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19 in People Aged ⩾60 Years
This study is a randomized, double-blinded, and placebo-controlled phase Ib/IIb clinical trial of the Inactivated SARS-CoV-2 Vaccine to evaluate the safety and immunogenicity of the vaccine in healthy people aged ⩾60 Years.
- Trial name
- NCT04470609
- Testing
- Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule, Medium dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule, High dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule
- Where
- China
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Musculoskeletal Diseases or Conditions, Traffic Accident
Safety and Efficacy of Integrative Korean Medicine Treatment for Elderly After Traffic Accident
The purpose of this study was to analyze the medical records of elderly traffic accident patients hospitalized at 4 branches of Jaseng Korean Medicine Hospital to determine the status of elderly patients and the effectiveness and…
- Conditions
- Musculoskeletal Diseases or Conditions, Traffic Accident, Elderly (People Aged 65 or More)
- Trial name
- NCT07007299
- Where
- 4 sites in South Korea
- Volunteers
- 1,788 people
- Sponsor
- Jaseng Medical Foundation
Aged
Feasibility Assessment of Implementing a Care System to PREVENT Iatrogenic Dependency (ID)
To assess the feasibility of a care system to prevent iatrogenic dependency during hospitalisation in people 70 years old and over. 2 cares units participate : one with routine care and the other with a care system to prevent ID.
- Trial name
- PREVENT-ID (NCT06173154)
- Testing
- Care system to prevent ID, Routine care
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Toulouse
Elderly
Interest of Using an Electric Wheelchair Equipped With Anti-collision Sensors for Elderly People in EHPAD
The device which is the subject of this investigation is a robotic assistance module for the driving of a semi-autonomous electric wheelchair (FRE).
- Trial name
- SWADAPT4 (NCT05378828)
- Testing
- Using anti-collision Sensors on electric wheelchairs, Use of an electric wheelchair without sensors
- Where
- 3 sites in France
- Volunteers
- 1 people
- Sponsor
- Pôle Saint Hélier
Executive Functions
Effects of Modern Board Games on Well Being in Older Adults
The aim of the study is to assess the effects of an intervention using modern board game-based learning in a sample of older individuals.
- Trial name
- JUMEMO3e+ (NCT06306365)
- Testing
- Modern board game-based learning
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Anorexia of Ageing
Impaired Regulation of Energy Balance in Elderly People (Balance Study)
Over the past century life expectancy has risen rapidly. As a result, the proportion of elderly people continues to grow. Elderly people probably have an impaired regulation of energy balance (energy intake versus energy…
- Trial name
- Balance (NCT00561145)
- Testing
- Energy restriction period
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Older People
Reablement in Residential Aged Care - a Randomized Controlled Trail
Background: The global increase in older adults presents challenges for maintaining health and autonomy in residential aged care (RAC) facilities, where passivity has been shown to often diminish quality of life.
- Trial name
- Re-RAC (NCT06793501)
- Testing
- Reablement intervention, Control group
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Region Örebro County
Sarcopenia, Syndrome; Institutionalization
Preventive Physiotherapy Intervention in Elderly People With Sarcopenia
This study evaluates two strength training protocols (one in peripheral muscles and one in inspiratory muscles) in the improvement of skeletal muscle mass and function in institutionalized elderly with sarcopenia.
- Trial name
- NCT02120586
- Testing
- Inspiratory Muscle Training (IMT)., Peripheral muscle training
- Where
- Spain
- Volunteers
- 91 people
- Sponsor
- University of Valencia
Geriatric Care
Clinical Trial on the Effectiveness of the Model of Centered Care in the Person in the Geriatric Population at Home(Project AICP.Com)
It is an individualized care model and therefore difficult to define in a concrete way: it is based on respect for the individual characteristics of each person (their beliefs, values, preferences, life history, projects…
- Trial name
- AICPcom (NCT05534737)
- Testing
- MAICP + usual care of social services, Control
- Where
- Spain
- Volunteers
- 240 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Exercise, Old Age
Effects of Ba Duan Jin Training for Older People
Baduanjin is one of the widely circulated fitness methods. The Ministry of Health, the Ministry of Education and the General Administration of Sports of China have vigorously promoted it as one of the contents of health and…
- Trial name
- NCT06550661
- Testing
- Ba duan jin
- Where
- Taiwan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Central Taiwan University of Science and Technology
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