Clinical trials: Elderly Women
Menopause, Cardiac Function Impaired
Effects of Exercise Training on Cardiovascular Health in Middle-aged Women
The hypothesis of the present study is that physical training can oppose detrimental changes in cardiovascular and metabolic health associated with estrogen loss after menopause.
- Conditions
- Menopause, Cardiac Function Impaired, Cardiovascular Diseases, Blood Platelet Disorders
- Trial name
- NCT02135575
- Testing
- Spinning
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Psychological Stress
Meditation Apps for Stress Management in Black Women
This randomized remote pilot study will evaluate the feasibility, acceptability, and preliminary effects of two meditation and mindfulness applications among approximately 40 Black women ages 35-64 experiencing moderate to high…
- Trial name
- NCT07807501
- Testing
- Exhale™ Meditation App, Levelhead Mindfulness App
- Volunteers
- 40 people
- Sponsor
- Arizona State University
Chronic Kidney Diseases, Cardiovascular Diseases
Testosterone and Vascular Function in Reproductive-Aged Females With Chronic Kidney Disease
Cardiovascular disease (CVD) is the leading cause of death among women and women with chronic kidney disease are at an even greater risk of CVD.
- Trial name
- NCT06107166
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- University of Calgary
Dietary Habits
Improving Diet Protein Intake in Middle-aged Women
The study sought to examine the effectiveness of nutrition education with and without diet coaching on dietary protein intake and muscle mass, strength and function among a group of middle-aged women.
- Trial name
- NCT04660851
- Testing
- Coached
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Depression
Prevention of Suicide in the Elderly
The purpose of this study is to design a program to prevent suicide in elderly patients by educating patients, their families, and physicians on depression and suicidal thoughts.
- Trial name
- NCT00000367
- Testing
- Treatment of depression, Suicide prevention intervention, Suicide prevention treatment
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Frail Elderly Syndrome
Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women
This is a pilot study to evaluate whether targeting inflammation will help reduce markers of insulin resistance inflammation, bone resorption and physical dysfunction in elderly women with gait disturbance.
- Trial name
- AFFIRM (NCT03430037)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Fragility Fracture
Hip Fracture Prevention Follow-up of Elderly Women in Primary Health Care
Researchers plan a 2022 follow-up of medical records data to investigate fracture incidence and survival for 1248 women, born 1902-1931, in a comparative fracture prevention study with 435 participants from an intervention area…
- Trial name
- HIP22 (NCT05269979)
- Testing
- Prevention of hip fractures
- Volunteers
- 1,248 people, healthy volunteers welcome
- Sponsor
- Kronoberg County Council
Kidney Diseases, Metabolic Acidosis
Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5
This clinical trial aims to investigate and test the effect of an acid/base diet in chronic kidney disease (CKD) patients, CKD stage 4 and 5.
- Conditions
- Kidney Diseases, Metabolic Acidosis, Renal Insufficiency, CKD
- Trial name
- REMA-CKD (NCT05784389)
- Testing
- Low PRAL
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Chronic Kidney Disease (CKD), Elderly
Sertraline and the Risk of Serious Adverse Events
The goal of this population-based cohort study is to assess the safety of initiating a new outpatient prescription of 50 mg/day of Sertraline, a higher dose, compared to 25 mg/day, a lower dose, in adults aged 65+ with low kidney…
- Conditions
- Chronic Kidney Disease (CKD), Elderly, Outpatient
- Trial name
- NCT07387120
- Testing
- Sertraline 50 mg, Sertraline 25 mg
- Where
- Canada
- Volunteers
- 6,893 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Aging, Inspiratory Muscle Weakness
Effect of Inspiratory Muscle Training on Diaphragm Muscle Thickness, Fatty Liver Density and Aerobic Capacity in Elderly Men: A Randomized Controlled Trial
This randomized controlled trial aims to investigate the effects of a 4-week inspiratory muscle training (IMT) program on diaphragm muscle thickness, fatty liver density, functional capacity, and quality of life in elderly men…
- Conditions
- Aging, Inspiratory Muscle Weakness, Fatty Liver, Reduced Functional Capacity
- Trial name
- IMT AND ELDERL (NCT07193082)
- Testing
- Experimental Inspiratory Muscle Training (IMT Group), Control Group: No inspiratory muscle training.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Infertility
Embryo QUAlity in Ovarian Stimulation With hMG.
Ovarian stimulation (OS) is a key component of IVF, aimed at increasing oocyte yield and improving embryo development potential.
- Trial name
- EQUAM (NCT07691073)
- Testing
- 10 mcg of follitropin-delta + 150 of hMG, 5 mcg of follitropin-delta + 225 of hMG
- Where
- 4 sites in Spain
- Volunteers
- 240 people
- Sponsor
- Fundacion Dexeus
Sleep Quality, Compliance
Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women
Time-restricted Eating (TRE) is a dietary approach that limits food intake to 4 - 12-hour windows without intentionally altering diet quality.
- Conditions
- Sleep Quality, Compliance, Physical Activity, Sedentary Behaviors
- Trial name
- DAWG-TREAT (NCT07520786)
- Testing
- Time Restricted Eating, Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Cervical Intraepithelial Neoplasia, Cervical Cancer
Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m)
The primary objective of this study is to evaluate the immuno-persistence (type specific IgG antibody) of the tested vaccine administered in girls aged 9-17 years,comparing to young healthy adults of 18-26 years who received the…
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Vaginal Intraepithelial Neoplasia, Vulvar Intraepithelial Neoplasia
- Trial name
- NCT04704908
- Testing
- Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli)
- Where
- China
- Volunteers
- 979 people
- Sponsor
- Jun Zhang
Embryo Aneuploidies, Implantation Rates
Preimplantation Genetic Screening (PGS) in Advanced Female Age and Male Severe Factor
Preimplantation Genetic Screening (PGS) is used for the selection of chromosomally normal embryos before the transfer in IVF treatments in many cases.
- Conditions
- Embryo Aneuploidies, Implantation Rates, Infertility
- Trial name
- NCT01571076
- Testing
- PGS, Prolonged culture
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Igenomix
Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric
Perineal Preparation for Pregnant Ladies.
Pregnant participants will be recruited at the obstetrics outpatient clinic during their visits 4 weeks before the due date. They are randomized into two groups. The first group will be educated to do digital perineal massage.
- Conditions
- Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric, Pelvic Floor Muscle Weakness
- Trial name
- NCT03287258
- Testing
- 3 program, one program
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Elderly, Older Adults, Aging Brain
Effects of Physical Exercise and Cognitive Training on Quality of Life in Older Women
Ageing exposes people to a progressive loss of cognitive and functional abilities, especially in women. The aim of the study is to investigate the effectiveness of different types of intervention, based on physical exercise…
- Trial name
- INCOGNITO (NCT07244562)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Exercise plus cognitive training, Exercise plus cognitive stimulus at home
- Where
- Italy
- Volunteers
- 124 people
- Sponsor
- University Hospital of Ferrara
Overactive Bladder
Fall Prevention in Older Adults With OAB
Though OAB treatment may improve physical activity, there is a lack of easily administered instruments for measuring physical activity in older adults.
- Trial name
- NCT03946124
- Testing
- Fesoterodine
- Volunteers
- 74 people
- Sponsor
- University of Pennsylvania
Healthy
A Study of Single and Multiple Ascending Doses of TC-5214 in Japanese Healthy Elderly Male and Female Volunteers
The purpose of this study is to assess safety, tolerability and pharmacokinetics of TC-5214 in elderly healthy Japanese volunteers.
- Trial name
- NCT01392820
- Testing
- TC-5214
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Alzheimer's Disease
A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects
This is a randomized, double-blind (Investigator and subject-blinded) placebo-controlled, multiple, ascending-dose study to evaluate the safety, tolerability, and pharmacokinetic profile of BPN14770 in healthy young and elderly…
- Trial name
- NCT02840279
- Testing
- BPN14770
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Tetra Discovery Partners
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