Clinical trials: Elderly Women
HPV Infections, Cervical Cancer
Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years
This phase 3 study will evaluate the immunogenicity and safety of 9-valent HPV recombinant vaccine in Chinese females aged 9 to 45 years
- Conditions
- HPV Infections, Cervical Cancer, Vulvar Cancer, Vaginal Cancer
- Trial name
- NCT04895020
- Testing
- 9-valent HPV vaccine
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Bladder Cancer
Prediction of Impaired Survival in Elderly Bladder Cancer Patients Opting for Radical Cystectomy
The investigators proposes a prospective cohort study in patients with high risk bladder cancer who have opted for radical cystectomy.
- Trial name
- NCT02039310
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Michigan
Urinary Incontinence in Old Age
Urinary Incontinence in Older Hong Kong Women: A Cross-sectional Study
This is a prospective, cross-sectional study aim to include 1000 patients with urinary incontinence and 100 healthy controls in Hong Kong.
- Trial name
- PROMOTE (NCT07243223)
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Healthy Subjects, Pharmacokinetics of ASP015K
A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K
The objective of this study is to explore safety and tolerability of multiple oral doses of ASP015K in healthy volunteers.
- Conditions
- Healthy Subjects, Pharmacokinetics of ASP015K, Pharmacodynamics
- Trial name
- NCT01364974
- Testing
- ASP015K
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Urinary Incontinence (UI), Urinary Incontinence
URINARY INCONTINENCE AND GERIATRIC SYNDROMES
The aim of this cross-sectional observational study is to examine the independent associations of urinary incontinence severity and post-void residual urine volume with frailty and other geriatric outcomes in older adults…
- Conditions
- Urinary Incontinence (UI), Urinary Incontinence, Urinary Incontinence in Old Age, Urinary Incontinence in Geriatric Population
- Trial name
- NCT07813702
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- MERT UYSAL
HPV Infections
V501 Efficacy Study in Women Aged 18 to 26 (V501-027)
A study to evaluate the efficacy, immunogenicity, safety and tolerability of V501 in adult women
- Trial name
- NCT00378560
- Testing
- Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
- Volunteers
- 1,021 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Perioperative Cardiavascular Complication, Peroperative Complication
Perioperative Management of Risk Factors in the Elderly Patients
In 2017, the number of operations on hospitalized patients in China was more than 57 million, of which more than 20 million were performed on elderly patients (≥65 years of age).
- Conditions
- Perioperative Cardiavascular Complication, Peroperative Complication, Perioperative Pulmonary Complication, Perioperative Neurological Complication
- Trial name
- NCT04967872
- Testing
- Implementing risk management and control plan for the elderly during perioperative period
- Where
- China
- Volunteers
- 4,782 people
- Sponsor
- Ailin Luo
Chronic Kidney Disease
Serotonin Norepinephrine Reuptake Inhibitors and the Risk of Serious Adverse Events
This is a population-based retrospective, new-user design, active comparator cohort study assessing whether initiating a new outpatient prescription of high-dose serotonin norepinephrine reuptake inhibitors (SNRIs)-venlafaxine…
- Trial name
- NCT07531173
- Testing
- Venlafaxine or duloxetine
- Volunteers
- 8,688 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cervical Cancer, Genital Wart
Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9
This study will evaluate the immunogenicity and safety of Zerun 9-valent HPV recombinant vaccine in healthy female 16-26 years of age by comparing with GARDASIL®9.
- Conditions
- Cervical Cancer, Genital Wart, CIN, VIN
- Trial name
- NCT05580341
- Testing
- Zerun HPV-9, GARDASIL ®9
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Craniopharyngioma, Child
SEMAFORCRANIO : Multicenter, Double-blind, Parallel, Randomized Controlled Trial of the Efficacy of Semaglutide in Hypothalamic Obesity Secondary to Craniopharyngioma in Children Aged 12 to 17 Years
Craniopharyngioma (CP) is a rare embryonic brain tumor of the sellar and parasellar region. Despite its benign histologic characteristics, it is locally aggressive and may cause severe morbidity from invasion into adjacent…
- Trial name
- SEMAFORCRANIO (NCT07845994)
- Testing
- Semaglutide (Wegovy) weekly injection
- Where
- 17 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Sleep Onset Latency
Evaluation of an Herbal Extract on Sleep Parameters
The overall purpose of this interventional study is to investigate how a specific herbal extract influences the quality of sleep in middle-aged women with mild to moderate insomnia.
- Trial name
- NCT05829902
- Testing
- Herbal extract drink
- Where
- Sweden
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aventure AB
Stage I Ovarian Cancer AJCC v6 and v7, Stage IA Fallopian Tube Cancer AJCC v6 and v7
Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
This trial studies the chemotherapy toxicity on quality of life in older patients with stage I, stage II, stage III, or stage IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer.
- Conditions
- Stage I Ovarian Cancer AJCC v6 and v7, Stage IA Fallopian Tube Cancer AJCC v6 and v7, Stage IB Fallopian Tube Cancer AJCC v6 and v7, Stage IC Fallopian Tube Cancer AJCC v6 and v7
- Trial name
- NCT01366183
- Testing
- Assessment of Therapy Complications, Carboplatin, Filgrastim
- Where
- 357 sites in United States
- Volunteers
- 290 people
- Sponsor
- Gynecologic Oncology Group
Ovarian Cancer, Surgery
PROADAPT-ovary/EWOC-2
PROADAPT is a standardized geriatric intervention that is currently being co-constructed during an exploratory phase on a multi-professional and multi-disciplinary basis after a systematic analysis of published data (Figure).
- Trial name
- NCT04284969
- Testing
- PROADAPT program
- Where
- 11 sites in France
- Volunteers
- 292 people
- Sponsor
- Hospices Civils de Lyon
Osteoporosis
Nutrition Education to Promote Calcium Intake Among 30-65 Year-old Women in Vietnam
Osteoporosis is an important public health problem in Vietnam, with one in ten Vietnamese women suffering from it. There is enough evidence demonstrating that low calcium intake is one of the risk factors for osteoporosis among…
- Trial name
- NCT04196426
- Testing
- Nutrition education intervention about osteoporosis and calcium
- Where
- Vietnam
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Breast Cancer, Gastrointestinal Cancer
A Feasibility Trial of Geriatric Assessment and Management for Older Cancer Patients
The purpose of this study is to determine the feasibility of implementing a randomized controlled study of the intervention (Geriatric Assessment followed by an integrated care plan carried out by the multidisciplinary geriatric…
- Conditions
- Breast Cancer, Gastrointestinal Cancer, Genitourinary Cancer
- Trial name
- NCT02222259
- Testing
- GA and Integrated Care Plan
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Toronto
Cognitive Decline, Postmenopausal Disorder
Response of Sex Hormones and Different Functions to Exercise and Diet in Elderly Women
It is an interventional study in which 60 women estimated to enroll according to random allocation and divided into two groups. The study group will receive aerobic exercise in addition to diet restriction while the control group…
- Trial name
- NCT04492540
- Testing
- aerobic exercise and MIND diet program, MIND diet program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Healthy Volunteer, Pharmacokinetics of YM178
A Study to Investigate the Food Effect on the Pharmacokinetics of YM178 in Healthy, Non-elderly Volunteers
The purpose of the study is to evaluate the effect of food intake on the pharmacokinetics of YM178 in healthy, non-elderly adult subjects.
- Trial name
- NCT00965926
- Testing
- YM178
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Myeloid Cell Infiltration
Effect of Rg1-based Supplementation on Exercise Training-induced Stem Cell Recruitments and Skeletal Muscle Adaptation in Women Aged > 60
This study will provide novel insights into the role of bone marrow-derived stem cells in muscle adaptation to long-term exercise and advance our understanding of an Rg-1 based supplement-Senactiv® as a potential intervention for…
- Trial name
- Senactiv (NCT07703774)
- Testing
- Resistance exercise
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Taipei
Nutrition, Healthy
The Impact of Plant-based Blends on Skeletal Muscle Protein Synthesis Rates in Older Adults
Lifestyle interventions such as physical activity and dietary habits are the most effective non-pharmacological strategies to combat the loss of muscle mass and the development of mobility limitations with aging.
- Trial name
- NCT05917223
- Testing
- Milk protein ingestion, Cron protein ingestion, Corn+Pea protein ingestion
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- McMaster University
Apparently Healthy and Not Receiving Hormonal Therapy
Examining the Impact of Phytoestrogens Supplementation on the Gene Expression, and Premenstrual Syndrome in Primenopausal Women
This randomized, double-blind, placebo-controlled clinical trial investigated the effects of flaxseed-derived phytoestrogen supplementation on selected gene-expression markers and premenstrual syndrome (PMS) severity among…
- Trial name
- NCT07310485
- Testing
- SDG lignans
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Jordan
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