Clinical trials: Elders
Depression
Cognitive Correlates of Antidepressant Treatment Response in Elders
Major depression is a very common health problem affecting older persons. The present standard of treatment is with medications called "antidepressants".
- Trial name
- NCT01477268
- Testing
- Zoloft (antidepressant)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Aging
CARESSES Testing and Evaluation Phases
The aim of this study is to conduct and evaluate a controlled experimental trial aimed at exploring whether, to what extent and how a socially-assistive Pepper robot that operates on a unique CARESSES cultural competence solution…
- Trial name
- CARESSES (NCT03756194)
- Testing
- Socially-assistive Pepper robot with a CARESSES cultural competence solution, Socially-assistive control Pepper robot with an alternative CARESSES solution
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Sense of Community
Community Spirit in Residence for the Elderly
The objective of our study is to observe and understand factors that emphasizes the creation of a community spirit. Specific objectives: 1.
- Trial name
- 437_EsCom (NCT06441877)
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- TOPMED
Elders
Turkish Version of Lower Extremity Functional Scale in Elders
This study was conducted in order to analyze the validity and reliability, and psychometric properties of the Turkish version of the Lower Extremity Functional Scale (LEFS-T) in elder adults.
- Trial name
- NCT05035329
- Testing
- Outcome measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Elder Abuse, Self Neglect
Effectiveness of RISE as a Community-Based Stand-Alone Elder Abuse Intervention Model
The goal of this randomized clinical trial is to learn if the RISE intervention can improve the well being of older adults who are at risk of or experiencing elder abuse or self-neglect (EASN).
- Trial name
- NCT07527962
- Testing
- RISE Model, Brief Consultation and Resource Sharing
- Where
- 2 sites in Canada
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- RISE Collaborative
Flu Vaccine
Senescent Immunity in Elders and Vaccine Responses (SILVER)
To study the effects of age on the immune system's response to flu vaccine and to study the connection between the immune system and physical and cognitive changes associated with aging.
- Trial name
- NCT04077424
- Testing
- Fluzone-High Dose Quadrivalent, Fluad, Flublock
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Aging
Affordable Mobile Robots for the Elderly
This project develops and tests the use of service robots to track health of the elderly over time. The objectives are to develop a low-cost mobile manipulator capable of a limited set of elder- relevant manipulation tasks (e.g.
- Trial name
- NCT02807506
- Testing
- Mobile Service Robot, Survey
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Elder Abuse, Elder Mistreatment
Feasibility of Elder Mistreatment VOICES-CI Screening Tool
The aim of this study is to assess the feasibility of the VOICES Elder Abuse Intervention among older adults with cognitive impairment.
- Trial name
- VOICES-CI (NCT05216081)
- Testing
- Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Yale University
Covid19, SARS-CoV Infection
Reactogenicity, Safety and Immunogenicity of QazCovid-in® COVID-19 Vaccine
Randomized, blind, placebo-controlled phase- i study and randomized, open phase phase-ii study of QAZCOVID-IN®- COVID-19 inactivated vaccine in healthy adult volunteers from 18 years old and elder
- Conditions
- Covid19, SARS-CoV Infection, Vaccine Adverse Reaction
- Trial name
- NCT04530357
- Testing
- QazCovid-in® - COVID-19 inactivated vaccine
- Where
- Kazakhstan
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Research Institute for Biological Safety Problems
Sleep
Evaluation of SLEEP Program
This study tests the effectiveness of a new educational intervention designed to improve sleep outcomes among an older adult population.
- Trial name
- NCT04727619
- Testing
- SLEEP program
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Aging, Cognitive Decline
Aging and Cognitive Health Evaluation in Elders (ACHIEVE)
The ACHIEVE study will be a randomized controlled trial nested within the infrastructure of the Atherosclerosis Risk in Communities (ARIC) study.
- Trial name
- ACHIEVE (NCT03243422)
- Testing
- Successful aging health education intervention, Hearing intervention
- Where
- 4 sites in United States
- Volunteers
- 977 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Inflammation
Oxytocin Aging Study
The life expectancy of older Americans continues to increase, with persons aged > 65 years representing the fastest growing segment of the US population (Manton et al., 1995).
- Trial name
- NCT02069431
- Testing
- Intranasal Oxytocin spray
- Where
- 2 sites in United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging, Alzheimer's Disease
Effects of Exercise and Cognitive Training on Cognitive Function in Older Adults
The purpose of this study is to gain a better understanding of the effects of exercise and cognitive training on improving brain function in healthy older adults who may be at risk for developing Alzheimer's Disease.
- Trial name
- NCT01038726
- Testing
- Exercise Training, Cognitive Training, Flexibility Training
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Caregivers, Family Relations
Knowledge and Interpersonal Skills to Develop Exemplary Relationships
This pilot study will test the effect of an online asynchronous psychoeducational intervention to improve relationship quality and prevent verbal-type elder mistreatment in caregiving dyads.
- Conditions
- Caregivers, Family Relations, Domestic Violence, Elder Abuse
- Trial name
- KINDER (NCT03593564)
- Testing
- KINDER
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Elder
Pharmacokinetics of ZSP1273 in Elder Participants
The purpose of this study is to assess the safety, tolerability and PK of ZSP1273 in elder Participants
- Trial name
- NCT06157450
- Testing
- ZSP1273
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Depression, Anxiety, Fatigue
Feasibility Study of a Modified Yoga Program for Elders
The purpose of this study is to determine whether a modified yoga program helps improve pain and function in elders age 65 years or older living in an assisted living community.
- Conditions
- Depression, Anxiety, Fatigue, Pain, Chronic, Sleep
- Trial name
- NCT04343625
- Testing
- Modified yoga class
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Tooth Loss, Periodontal Disease
"Clinical Trials to Enhance Elders' Oral Health" ("TEETH")
The purpose of this study is to determine if regular rinsing with chlorhexidine is effective as a long-term preventive method for reducing the incidence of tooth loss in low income older adults.
- Conditions
- Tooth Loss, Periodontal Disease, Tooth Decay
- Trial name
- NCT00004640
- Testing
- Chlorhexidine rinse
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,101 people, healthy volunteers welcome
- Sponsor
- University of Washington
Stress, Loneliness
Therapeutic Melodies: How Classical Turkish Music Soothes Stress and Eases Loneliness
This study investigated the impact of traditional classical Turkish music as a telehealth intervention on reducing stress and loneliness among elderly individuals.
- Conditions
- Stress, Loneliness, COVID-19 Pandemic, Elderly
- Trial name
- NCT05859893
- Testing
- Classical Turkish Music Sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ege University
Functional Fitness, Health Promotion
12-week Pilates Program on Community-dwelling Middle-aged Women
The purpose of this study was to investigate the effects of a Pilates exercise intervention program on functional physical fitness in community-dwelling middle-aged women.
- Conditions
- Functional Fitness, Health Promotion, Exercise, Frail Elderly Syndrome
- Trial name
- NCT05333484
- Testing
- Programed Pilates
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Diabetes Mellitus, Microbiome
Supplementation of Inulin + L. Acidophilus in Elders With T2DM
This study investigates the effects of a symbotic supplement (Inulin + Lactobacillus acidophilus) on cognitive impairment in older adults with type 2 diabetes mellitus (T2DM).
- Conditions
- Diabetes Mellitus, Microbiome, Cognition Disorders
- Trial name
- NCT06830824
- Testing
- Lactobacillus acidophilus
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Anahuac University