Clinical trials: Elective
Chronic Pain
Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal Surgery
This is a randomized, prospective, double-blind , placebo-controlled trial examining the effects of intraoperative dexmedetomidine infusion on pain in patients undergoing lumbar spinal fusion surgery.
- Trial name
- NCT03325972
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- NYU Langone Health
Laryngeal Masks, Pharyngitis
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect…
- Conditions
- Laryngeal Masks, Pharyngitis, Minors, Anesthesia
- Trial name
- NCT03140228
- Testing
- I-Gel, LMA
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
PreDiabetes
Digital Diabetes Prevention Program Study
The aim of this study is to determine if completion of the Diabetes Prevention Program (DPP) via the Transform 10 website can significantly decrease hemoglobin A1c (HbA1c) levels and Body Mass Index (BMI) in prediabetic…
- Trial name
- NCT06137963
- Testing
- Transform10 Diabetes Prevention Program
- Where
- United States
- Sponsor
- Hospital for Special Surgery, New York
Erector Spina Plan Block, Preemptive Analgesia
Comparison of the Effect of Preemptive and Post-operative Erector Spina Plane Block on Intraoperative Opioid Consumption and Postoperative Analgesia in Patients Who Will Undergo Elective Thoracotomy Surgery, Guided by the Nociception Level Index (NoL)
The patients who will participate in the study will be determined and informed according to the inclusion and exclusion criteria, and the patients who signed the informed consent form will be included in the study.52 patients who…
- Conditions
- Erector Spina Plan Block, Preemptive Analgesia, Thoracotomy, Nociception Level Index(NoL)
- Trial name
- NCT05944523
- Testing
- Erector Spina Plan Block
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ankara University
Frailty
Intraoperative EEG Marker of Preoperative Frailty in Elderly Patients
Frailty is a state of vulnerability, characterized by a loss of mechanisms that maintain homeostasis, determining a lower capacity for recovery in the event of a stressful incident.
- Trial name
- NCT04783662
- Testing
- Intraoperative frontal electroencephalogram
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain, IL-1 Beta
Comparison of the Ultrasound Guided Effects of the Erector Spina Plane Block and Quadratus Lumborum Block Methods on Postoperative Analgesia and Plasma Cytokine Levels in Elective Cesarean Operations
Comparison of Two Different Analgesic Techniques for Reducing Postoperative Pain After Cesarean Section
- Trial name
- NCT07901829
- Testing
- QL (quadratus lumborum) block, Erector Spinae Plane Block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Education and Research Hospital
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Pain, Postoperative
Intrathecal Additives for Spinal Anaesthesia in Elective Caesarean Sections
we designed this randomized, single -blind, prospective clinical study to test postoperative analgesia of three intrathecal additives in elective caesarean sections which are magnesium, dexamethasone and dexmedetomidine.
- Trial name
- NCT04747171
- Testing
- intrathecal Magnesium, intrathecal dexamthasone, intrathecal dexmedetomidine
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Benha University
Postoperative Pain, Postoperative Nausea and Vomiting
A Study to Assess Analgesic Efficacy of Intravenous Lignocaine
The primary objectives of this study are to analyse the effect of perioperative systemic infusion of lignocaine on postoperative pain, postoperative nausea and vomiting and perioperative levels of inflammatory mediators in…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Postoperative Ileus
- Trial name
- NCT01699919
- Testing
- Intravenous lignocaine
- Where
- India
- Volunteers
- 134 people
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Pain, Postoperative, Cesarean Section
Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section
The purpose of this prospective single center, randomized study is to determine if ultrasound guided Transversus Abdominis Plane (TAP), Quadratus Lumborum (QL), and Erector Spinae Plane (ESP) blocks decrease opioid consumption in…
- Trial name
- NCT03695172
- Testing
- Ropivacaine, TAP block, QL block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Duke University
Cholelithiasis
Cholecystectomy vs EUS-guided GBD With Stone Removal
In this new era of less invasive procedures, the indications for endoscopic ultrasound (EUS)-guided gallbladder drainage (GBD) are rapidly expanding.
- Trial name
- NCT06038201
- Testing
- LAMS placement for cholecystostomy, Laparoscopic cholecystectomy
- Where
- Ecuador
- Volunteers
- 56 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colorectal Surgery
MOBILE Trial. Mechanical and Oral Antibiotic Bowel Preparation Versus no Bowel preparatIon for eLEctive Colectomy - a Multicenter, Prospective, Randomized, Controlled Trial.
Enchanced recovery after surgery (ERAS) protocols aim to provide safer and quicker recovery postoperatively. One of the elements in ERAS protocols is that bowel is not prepared before colorectal surgery.
- Trial name
- NCT02652637
- Testing
- neomycin, metronidazole, polyethylene glycol (PEG)
- Where
- 4 sites in Finland
- Volunteers
- 417 people
- Sponsor
- Helsinki University Central Hospital
Heart Catheterization
Randomized, Open Label Study of Dabigatran Etexilate in Elective Percutaneous Coronary Intervention
To assess whether two doses of dabigatran etexilate (110 mg twice daily (b.i.d) and 150 mg twice daily (b.i.d)) as compared to unfractionated heparin (UFH), both in addition to a standard dual antiplatelet regimen, provide…
- Trial name
- NCT00818753
- Testing
- dabigatran 110 mg, dabigatran 150 mg, unfractionated heparin
- Where
- 4 sites in Netherlands
- Volunteers
- 53 people
- Sponsor
- Boehringer Ingelheim
Postoperative Cognitive Dysfunction
Effects of Amantadine on Postoperative Cognitive Dysfunction
Post-operative cognitive dysfunction (POCD) is a fairly well-documented clinical phenomenon. Investigators will determine whether amantadine can reduce the occurrence of POCD in elderly patients with major abdominal surgery.
- Trial name
- NCT03527134
- Testing
- Amantadine
- Where
- China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Zhiyi Zuo
Elective Laparoscopic Cholecystectomy
The Effect of Respiratory Exercises on Abdominal Distension in Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is the first-line treatment for symptomatic gallstones. Pneumoperitoneum is the process of expanding the abdominal cavity during the surgical procedure by introducing CO2 gas into the abdomen to widen…
- Trial name
- NCT06069557
- Testing
- Respiratory exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Transient Tachypnea of the Newborn
Reducing Respiratory Distress After Elective Caesarean Birth Through Knee-chest-flexion: a Randomized Controlled Trial
Planned caesarean birth is a risk factor for the development of neonatal respiratory distress commonly known as transient tachypnoea of the newborn.
- Trial name
- NCT06270823
- Testing
- Knee-to-chest-flexion manoeuvre
- Where
- Tanzania
- Volunteers
- 562 people
- Sponsor
- Kilimanjaro Clinical Research Institute
Trauma, Surgery
Sublingual Sufentanil PCA Usability for Postoperative Pain (Zalviso® System)
Intravenous patient-controlled analgesia (iv-PCA) is the gold standard for the treatment of moderate to severe postoperative pain. It is used in more than 20% of cases after major surgery.
- Trial name
- USE-SSPC (NCT03373851)
- Testing
- Zalviso Device
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Hospices Civils de Lyon
Coronary Artery Disease
Colchicine Protective Effect in Patients Undergoing Percutaneous Coronary Intervention (COLCHICINE-PROTECT)
The goal of this clinical trial is to evaluate the colchicine protective effect in patients undergoing Percutaneous Coronary Intervention (PCI).
- Trial name
- NCT05739929
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Helwan University
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
ULTRASOUND ASSESSMENT OF GASTRİC VOLUME IN PREGNANT WOMEN UNDERGOİNG ELECTİVE CESAREAN SECTİON, WITH AND WITHOUT GESTATİONAL DIABETES MELLITUS
THE PRIMARY OBJECTIVE OF THIS STUDY IS TO COMPARE GASTRIC VOLUME PRIOR TO ELECTIVE CESAREAN SECTION BETWEEN PREGNANT WOMEN DIAGNOSED WITH GESTATIONAL DIABETES MELLITUS (GDM) AND THOSE WITHOUT GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Preoperative Period, Nutritional Status
Preoperative Nutritional Status in Patients Undergoing Elective Total Knee Arthroplasty and In-hospital Postoperative Complications
Malnutrition has long been linked to postoperative complications and adverse outcomes in a variety of surgical fields , such as increased susceptibility to infection, delayed wound healing, and increased frequency of decubitus…
- Conditions
- Preoperative Period, Nutritional Status, Arthroplasty Knee
- Trial name
- NUTR TKA (NCT03549962)
- Testing
- TKA
- Where
- 2 sites in Hong Kong
- Volunteers
- 626 people
- Sponsor
- Chinese University of Hong Kong
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