Clinical trials: Elective
PreDiabetes
Digital Diabetes Prevention Program Study
The aim of this study is to determine if completion of the Diabetes Prevention Program (DPP) via the Transform 10 website can significantly decrease hemoglobin A1c (HbA1c) levels and Body Mass Index (BMI) in prediabetic…
- Trial name
- NCT06137963
- Testing
- Transform10 Diabetes Prevention Program
- Where
- United States
- Sponsor
- Hospital for Special Surgery, New York
Fluid Responsiveness, Hemodynamic Monitoring
Internal Jugular Venous Distensibility Index and Innominate Venous Flow Patterns As Predictors of Fluid Responsiveness
The measurement of internal jugular vein distensibility index corresponds to the measurement of stroke volume using trans-thoracic Doppler echocardiography in assessing the response to fluid administration in elective surgical…
- Trial name
- NCT05930600
- Testing
- Ultrasonography of Internal Jugular Vein, Doppler Echocardiograhy
- Where
- Indonesia
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Coronary Artery Disease, Drug Resistance
Effect of Clopidogrel Loading and Risk of PCI
This study is a prospective, single-center evaluation of the impact of the variability in platelet response after loading with clopidogrel on the peri-interventional risk of patients undergoing PCI.
- Trial name
- EXCELSIOR (NCT00457236)
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Gastric Residual Volume
Study of Effects of Preoperative Oral Domperidone on Gastric Residual Volume After Clear Fluid Ingestion in Patients Scheduled for Elective Surgeries
General Anesthesia requires preoperative fasting according to specific instructions. Regarding Fasting Guidelines, The American Society of Anesthesiologists (ASA) recommends patients to fast from fatty food or meat eight hours…
- Trial name
- NCT05570292
- Testing
- Domperidone, Folic acid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Wound Infection; Wounds; Dehisence; Cosmesis; Home Care; Length of Hospital Stay
Prophylactic Negative Wound Therapy in Laparotomy Wounds.
Post-operative wound issues in abdominal surgery have a significant impact on patient outcomes. The impact of different types of wound therapy are not clear in the literature.
- Trial name
- PROPEL (NCT03871023)
- Testing
- Smith & Nephew PICO Negative wound pressure versus standard dresing, PREVENA Negative pressure wound versus standard dressing
- Where
- Ireland
- Volunteers
- 240 people
- Sponsor
- St. James's Hospital, Ireland
Bilateral Inguinal Hernia Repair, Open Upper Abdominal Surgeries
Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries
To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per…
- Trial name
- NCT07853586
- Testing
- ultrasound guided anterior oudratus lumborum block, Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Frailty Syndrome, Prehabilitation
Multimodal Prehabilitation of Frail Patients Undergoing Elective Knee or Hip Replacement
Background: Frailty is a geriatric syndrome of reduced physiologic reserve that increases surgical risk and is common among older adults undergoing hip or knee replacement.
- Conditions
- Frailty Syndrome, Prehabilitation, Arthroplasties, Knee Replacement, Arthroplasties, Hip Replacement
- Trial name
- NCT07465159
- Testing
- Multimodal Prehabilitation
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- University of Iceland
Anxiety State, Child Behavior
Effects of Different Parental Involvement on Anxiety and Delirium
Induction of anesthesia in surgical procedures can be a distressing process for both children and their parents. Nonpharmacological behavioral interventions, unlike sedative medications, can reduce children's anxiety without…
- Trial name
- NCT06634680
- Testing
- Procedure: Selection of parent(mother or father) according to children preference, Procedure: Both parents will accompany the children.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Laparoscopic Abdominal Surgeries
Effect of Low-dose Pregabalin Retard (82.5 mg) Versus Standard-dose Pregabalin Retard (165 mg) on Postoperative Pain and Opioid Consumption After Elective Laparoscopic Abdominal Surgery
The goal of this clinical trial is to detect whether pregabalin retard (82.5 mg or 165 mg) improves analgesia after elective laparoscopic abdominal surgery in adults. It will also evaluate the safety of both doses.
- Trial name
- NCT07456761
- Testing
- Pregabalin retard 82.5 mg, Pregabalin retard 165 mg
- Volunteers
- 80 people
- Sponsor
- South Egypt Cancer Institute
Anesthesia, Child
Effect of PEEP on Gastric Insufflation During Face Mask Induction of General Anesthesia in Children
The aim of our study is first to assess the effect of different PEEP levels on gastric volume using ultrasonography during induction of general anesthesia in children undergoing elective surgery
- Trial name
- NCT06127173
- Testing
- Positive End Expiratory Pressure PEEP
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Kasr El Aini Hospital
Coronary Artery Disease, Postoperative Pulmonary Complications
Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and Diaphragm Function
Pulmonary atelectasis and loss of lung aeration are common complications following cardiac surgery with cardiopulmonary bypass (CPB) and are associated with impaired oxygenation and prolonged mechanical ventilation.
- Conditions
- Coronary Artery Disease, Postoperative Pulmonary Complications, Pulmonary Atelectasis, Postoperative, Diaphragm Dysfunction
- Trial name
- FCV-PCV-DTI-LU (NCT07800741)
- Testing
- Flow-Controlled Ventilation, Pressure-Controlled Ventilation (PCV)
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Blood Loss
Clonidine Versus Tranexamic Acid in Reduction of Blood Loss
Tranexamic acid is an antifibrinolytics agent that has been widely used in the reduction of blood loss at surgeries. Oral clonidine is an alpha-2 adrenergic agonist that has been used in various surgeries including Caesarean…
- Trial name
- NCT05371574
- Testing
- clonidine group
- Where
- Nigeria
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Uwakwe Emmanuel Chijioke
Staphylococcal Infections, Methicillin-resistant Staphylococcus Aureus
Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty
This study will evaluate the safety and effectiveness of daptomycin, an antibiotic compared to another one which is vancomycin when given around the time of joint replacement surgery.
- Trial name
- NCT01196169
- Testing
- Daptomycin, Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Mountain Home Research & Education Corporation
Surgery, Cancer
Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)
This is a randomized trial of intensified post-discharge surveillance (Intervention Arm) versus standard post-discharge surveillance (Control Arm).
- Trial name
- NCT05454280
- Testing
- Intensified post-discharge surveillance, Standard post-discharge surveillance
- Where
- United States
- Volunteers
- 526 people
- Sponsor
- Fox Chase Cancer Center
Intubation; Difficult or Failed
UED-A Videolaryngoscope vs. Glidescope Titanium for Elective Tracheal Intubation
The present randomized clinical trial wants to compare the efficacy and safety of UED-A videolaryngoscope to Glidescope Titanium for routinely tracheal intubation in 60 adults, in terms of successful rate, no.
- Trial name
- UED-VLG (NCT05721690)
- Testing
- UED-A Videolaryngoscopy, Glidescope Videolaryngoscopy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Cesarean Section
Optimal Site of Administration for Continuous Wound Infusion After Cesarean Section
The purpose of this randomized double-blind study is to evaluate in which anatomical layer (AF versus BF) continuous wound infusion of local anesthetics combined with NSAIDs through a multiorifice catheter has the best…
- Trial name
- NCT01160913
- Testing
- Continuous wound infusion, Continuous wound
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Association pour la Recherche et la Formation en Anesthésie Analgésie Réanimation
Colonoscopy
Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial
The primary aim of the study is to determine the rate sedation-induced adverse events, comparing BIS-guided sedation with clinical observation.
- Trial name
- BIS (NCT03453359)
- Testing
- BIS monitor, Ramsay scale
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hospital Galdakao-Usansolo
Frail Elderly Syndrome, Primary Prevention
Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques.
- Conditions
- Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty
- Trial name
- NPPOD (NCT05993754)
- Testing
- Non-pharmacological intervention
- Where
- Chile
- Volunteers
- 400 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Vitamin D, Spinal Fusion
The Effect of Oral Vitamin D Supplements on Fusion Outcome in Patients Receiving Elective Lumbar Spinal Fusion
The process of bony fusion is a dynamic bone remodeling process and a variety of risk factors have been identified to contribute to pseudoarthrosis.Vitamin D deficiency has been reported to be associated with more…
- Conditions
- Vitamin D, Spinal Fusion, Lumbar Spine Disease
- Trial name
- NCT05023122
- Testing
- vitamin D3, calcium
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Show Chwan Memorial Hospital
the Effect of Intraoperative Magnesium Infusion on Postoperative Cognitive Functions in Adult Patients After Elective Pelvi-abdominal Surgeries
Effect of Intraoperative Magnesium Infusion on Postoperative Pain and Cognitive Function
The aimof this study is to observe the effect of intraoperative magnesium infusion on peri-operative pain and postoperative cognitive functions in adult patients after elective pelvi-abdominal surgeries.
- Trial name
- NCT04256057
- Testing
- Magnesium Sulfate
- Where
- 3 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Beni-Suef University
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