Clinical trials: Elective
Postoperative Quality of Recovery, Postoperative Migrainous Headache
Effect of Sumatriptan on the Postoperative Quality of Recovery After Elective Minimally Invasive Craniotomy
Postoperative migrainous headache following craniotomy is distressing and may cause significant morbidity and often delay discharge from the hospital. The mechanism of this post craniotomy migraine is multifactorial.
- Trial name
- NCT01632657
- Testing
- Sumatriptan
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Colorectal Disorders
Does a Central Venous Line Reduce Perioperative Fluid Administration?
'Hypothesis-generating' study to assess whether the presence of a central venous line significantly affects the volumes of fluid infused perioperatively in major elective colorectal surgery
- Trial name
- NCT03985111
- Testing
- Central Venous Catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
Elective Surgery of the Spine by Laparotomy
The Tap Block Technique Via the Anterior Approach in Elective Surgery of the Spine
This is a prospective, single-centre, randomised, double-blind trial, comparing TAP block with continuous infiltration of ropivacaine versus placebo.
- Trial name
- TAPBloc Rachis (NCT02055664)
- Testing
- Ropivacaine 0.2%, Chlorure de sodium 0.9%
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Elective Surgical Patients
Comparison of Glottic Views and Intubation Times in the Supine and 25 Degree Back-up Positions
Our hypothesis is that the view of the glottis may be improved by putting all patients requiring intubation in the ramped or back up position while maintaining the classic sniffing position.
- Trial name
- NCT02934347
- Testing
- 25 degree back-up position
- Volunteers
- 781 people
- Sponsor
- Betsi Cadwaladr University Health Board
Paediatric Surgery, Anaemia
South African Paediatric Surgical Outcomes Study 2
Preoperative anaemia has been shown to be associated with worse outcomes after surgery in both adults and children. Limited research has been done on how common preoperative iron-deficiency anaemia (IDA) is in children and how…
- Conditions
- Paediatric Surgery, Anaemia, Iron Deficiency Anemia, Iron
- Trial name
- SAPSOS2 (NCT05681871)
- Testing
- Ferrous gluconate syrup or ferrous fumarate/folic acid tablets
- Where
- 2 sites in South Africa
- Volunteers
- 755 people
- Sponsor
- University of Cape Town
Idiopathic Pulmonary Fibrosis
The Predictive Ability of 4MGS in IPF
This study investigates whether usual walking speed, measured by the 4 metre gait speed test (4MGS), and change in usual walking speed over 6 months predicts death and hospital admissions in patients with Idiopathic Pulmonary…
- Trial name
- IPFMORT (NCT02436278)
- Testing
- 4MGS
- Where
- United Kingdom
- Volunteers
- 132 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Gastric Emptying
Ultrasound Assessment of Gastric Residual Volume in Children Scheduled for Elective Surgery After Clear Fluids Fasting for One Versus Two Hours: a Comparative Study
Ultrasound guided comparison of gastric residual volume after clear fluid fasting for one versus two hours in pediatrics scheduled for elective surgery.
- Trial name
- NCT04228497
- Testing
- gastric ultrasound, the clear fluid intake
- Where
- Egypt
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pain
Skin-to-skin Contact for Newborn First Injection Pain
This study is carried out to examine the effect of skin-to-skin contact on the pain and stress level of the first intramuscular injection after elective cesarean section.
- Trial name
- NCT05700552
- Testing
- skin to skin contact
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Brain Edema Caused by Drugs, Cerebral Oxygenation
Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome
The brain is a metabolic active organ with constant energy demands. Brain oxygen supply is secured via cerebral circulation. Brain tumor surgery is commonly associated with the tumor's underlying pathophysiology including brain…
- Trial name
- TIVolBrain (NCT06779890)
- Testing
- Sevoflurane, Desflurane
- Where
- 2 sites in Greece
- Volunteers
- 84 people
- Sponsor
- Georgia Tsaousi
Dysglycemia, Arthroplasty Complications
Recognition and Treatment of Dysglycemia. AGS - Acute Glucose Service
AGS (Acute Glucose Service ) is an inpatient glucose management service consisting of Nurse Practitioner and physician. Team manages not - consulted- based preoperative assessment, perioperative glucose control, patient education…
- Trial name
- AGS (NCT03306810)
- Testing
- AG service
- Where
- Finland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Anesthesia, Fasting
The Effect of Mobilization on Gastric Emptying Time
ıntroduction Pulmonary aspiration under general anesthesia is a rare but serious complication in healthy patients undergoing elective surgery.
- Trial name
- NCT05981638
- Testing
- group WM, group WR, Group AR
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Uludag University
Ultrasound, Difficult Laryngoscopy
Ultrasonographic Parameters in Prediction of Difficult Laryngoscopy in Non-suspected Difficult Airway Patients
This study aims to evaluate the ultrasonographic parameters (distance from skin to epiglottis (DSE) and distance from skin to vocal cords (DSVC)) as preoperative predictors of difficult laryngoscopy in non-suspected difficult…
- Conditions
- Ultrasound, Difficult Laryngoscopy, Prediction
- Trial name
- NCT06052189
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Tanta University
Liver Disease
Isoflurane Preconditioning for Liver Resections
The objective is to examine the efficacy of isoflurane (inhaled anesthetic gas) to induce clinically effective preconditioning in patients undergoing elective hepatic surgery.
- Trial name
- NCT01031550
- Testing
- isoflurane, propofol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Rutgers, The State University of New Jersey
Primary Non-operated Squamous Cell Carcinoma of Oral Cavity, Primary Non-operated Squamous Cell Carcinoma of Oropharynx
Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck
Severe acute and late dysphagia is now considered as a dose-limiting toxicity of radio(chemo)therapy for head and neck cancer that significantly affects patients' quality of life.
- Conditions
- Primary Non-operated Squamous Cell Carcinoma of Oral Cavity, Primary Non-operated Squamous Cell Carcinoma of Oropharynx, Primary Non-operated Squamous Cell Carcinoma of Hypopharynx, Primary Non-operated Squamous Cell Carcinoma of Larynx
- Trial name
- NCT01287390
- Testing
- video fluoroscopy, extra imaging, scoring acute toxicity
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Coronary Artery Disease
Feasibility and Safety Study Comparing REG1 Anticoagulation System With Unfractionated Heparin in Elective PCI
The purpose of this study is to determine if it is feasible and safe to use the REG1 Anticoagulation System instead of unfractionated heparin during percutaneous coronary intervention (PCI) in subjects with coronary artery…
- Trial name
- REVERSAL-PCI (NCT00715455)
- Testing
- REG1, Unfractionated Heparin
- Where
- 6 sites in United States, Argentina
- Volunteers
- 26 people
- Sponsor
- Regado Biosciences, Inc.
Cesarean Section Complications
Impact of Changing Sterile Glove at the Time of Wound Closure to Reduce Surgical Site Infection
Assessment of the impact of changing sterile gloves at the time of wound closure on reduction of SSI in women undergoing elective CS.
- Trial name
- NCT06257940
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Assiut University
Postoperative Pain, Hip Arthroplasty, Total
Comparison of Ultrasound-Guided Erector Spinae Plane Block and Quadro-Iliac Plane Block in Elective Primary Unilateral Total Hip Arthroplasty
This prospective, single-center, randomized controlled, double-blind (participant and outcomes assessor) trial compares ultrasound-guided erector spinae plane block (ESPB) and quadro-iliac plane block (QIPB) in adult patients…
- Trial name
- NCT07904585
- Testing
- Quadro-Iliac Plane Block (QIPB), Erector Spinae Plane Block
- Volunteers
- 80 people
- Sponsor
- Uludag University
Cardiac Disease
Patient Preferences and Experiences of Waiting for Heart Surgery
Waiting for heart surgery could be difficult and anxiety-provoking for some patients. Research suggests that some specific factors (e.g., individual coping strategies, communication with the clinical team, having a more active…
- Trial name
- NCT05996640
- Testing
- This is study does not use an intervention
- Volunteers
- 268 people
- Sponsor
- King's College London
Mechanical Ventilation Complication, Intensive Care Unit
INTELLiVENT-ASV Using Mainstream Versus Sidestream End-Tidal CO2 Monitoring
Background INTELLiVENT-ASV, an automated closed-loop mode of mechanical ventilation, available on Hamilton ventilators for clinical use, uses mainstream end-tidal CO2 (etCO2) monitoring to adjust minute ventilation.
- Conditions
- Mechanical Ventilation Complication, Intensive Care Unit, Postoperative Care
- Trial name
- INTELLiSTREAM (NCT04599491)
- Testing
- Sidestream capnography using the 'Respironics LoFlo Sidestream CO2 Module', Mainstream capnography using the 'Respironics Capnostat 5 Mainstream CO2 sensor'
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
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