Clinical trials: Elective
Platelet Dysfunction
clOpidogrel "resIstaNce" in a Selected Population of Patients at a Tertiary Cardiovascular Center in Trinidad
The aim of this study was to determine the prevalence of clopidogrel resistance among a selected group of patients undergoing elective percutaneous coronary intervention and to observe whether there was any south-Asian…
- Trial name
- POINT (NCT03667066)
- Testing
- Clopidogrel
- Where
- Trinidad and Tobago
- Volunteers
- 40 people
- Sponsor
- The University of The West Indies
Head and Neck Carcinoma
Post-Operative Radiotherapy De-Escalation of Negative Nodal Regions in Head and Neck Squamous Cell Carcinoma
This is a non-randomized prospective trial evaluating the non- inferiority of de-escalating the volume and/or dose of elective nodal irradiation in post-operative head and neck squamous cell carcinomas.
- Trial name
- NCT05650034
- Testing
- Elective nodal de-escalation arm
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- National Cancer Institute, Egypt
Colorectal Cancer, Insulin Resistance
Prehabilitation Versus Enhanced Recovery Program for Elective Colorectal Cancer Surgery.
Elective surgery is the most effective treatment option for colorectal cancer, however it has been recognized to be associated with high morbidity and mortality risks.
- Trial name
- PrehabVsERAS (NCT03758209)
- Testing
- Prehabilitation + ERAS, ERAS
- Where
- Hungary
- Volunteers
- 184 people
- Sponsor
- St. Borbala Hospital
Anxiety, Postoperative Pain
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
This prospective randomized controlled study aims to evaluate the anxiolytic effect of preoperative sublingual melatonin and its impact on postoperative pain scores when administered in two different doses to female patients…
- Conditions
- Anxiety, Postoperative Pain, Anesthesia
- Trial name
- NCT06997263
- Testing
- Melatonin 3 mg Sublingual, Melatonin 6 mg Sublingual
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Benha University
Coronary Artery Bypass, Cardiopulmonary Bypass
Role of Glutamine as Myocardial Protector in Elective On-Pump CABG Surgery With Low EF
Coronary artery disease has the highest mortality rate worldwide and coronary artery bypass grafting (CABG) is the most common cardiac surgery performed in patients with coronary artery disease to revascularize the heart.
- Conditions
- Coronary Artery Bypass, Cardiopulmonary Bypass, Coronary Artery Disease
- Trial name
- NCT04560309
- Testing
- L-alanyl-L-glutamine dipeptide
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Elective Caesarean Section
Sequential Intrathecal Injection of Fentanyl and Hyperbaric Bupivacaine
56 Parturients, aged 18-40 year, undergoing elective CS were randomly assigned to receive sequential intrathecal injection of fentanyl and hyperbaric bupivacaine at the same rate (normal sequential) NS or a rapid intrathecal…
- Trial name
- NCT03415087
- Testing
- sequential intrathecal injection, hyperbaric bupivacaine, fentanyl
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Satisfaction, Pain
Combined Spinal-epidural Versus Spinal Analgesia for Elective Caesarean Section in the Postoperative Period
Combined spinal epidural (CSEA) and single shot spinal anesthesia (SSSA) are both well-established anesthetic methods for caesarean section.
- Trial name
- NCT02273011
- Testing
- caesarean section
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. med. Daniel Reuter
Infertility
Diafert® for Embryo Selection and Fertility Improvement
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02593461)
- Testing
- Daifert, Control Group
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Forest Laboratories
Peripartum Anemia
Impact of Intraoperative Cell Salvage
Patients presenting for elective cesarean section will be screened for pre-procedural anemia. If the potential subject meets the selection criteria they will be presented with the option of participating in the study.
- Trial name
- NCT06240117
- Testing
- Intraoperative cellular salvage
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Fasting, Perioperative Pulmonary Aspiration
Gastric Volume After Drinking 175 ml of Ice Water Prior to Gastroscopy in Healthy Adult Patients
Recommendation for fluid fasting is two hours prior to anaesthesia, however, less may be acceptable. The current study compares ingestion of 175 ml ice water prior to elective gastroscopy vs.
- Trial name
- NCT05685446
- Testing
- Ice water
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Regionshospital Nordjylland
General Anesthesia, Laparotomy
Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy
The effects of anesthesia and surgery can lead to stress responses that result in hormonal and metabolic changes in the body. The immune system and the nervous system communicate both ways, and it was found that nociception and…
- Conditions
- General Anesthesia, Laparotomy, Inflammation
- Trial name
- PRO-Ketamine (NCT04462094)
- Testing
- Ketamine 0.3 mg/kg at end-of-surgery, Ketamine 0.3 mg/kg at anesthesia induction
- Where
- Indonesia
- Volunteers
- 68 people
- Sponsor
- Udayana University
Pain
From ACute To Chronic Postoperative Shoulder Pain in Patients for Elective Lobectomy
Shoulder pain is a well known problem after thoracical surgery. The pathogenesis of the pain is uncertain, but mainly a mix of referred pain and mechanical strain to the shoulder. It is believed to last a few days.
- Trial name
- FACTS2 (NCT01552746)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Total Hip Arthroplasty (THA)
Impact of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Elective Hip Replacement
In the present project, the framework conditions of outpatient rehabilitation at the Bonn Center for Outpatient Rehabilitation will now be used to prove whether sports science-controlled strength and BFR training has a similar…
- Trial name
- NCT07043127
- Testing
- BFR
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Nasopharyngeal Carcinoma
Elective Level Ib Irradiation in Nasopharyngeal Carcinoma Patients Based on the International Guidelines
Currently, nasopharyngeal carcinoma (NPC) patients who had level II involvement with extracapsular extension (ECE), and/or had a maximum nodal axial diameter (MAD) of greater than 2cm in level II will be recommended to receive…
- Trial name
- NCT05519956
- Testing
- level Ib-covering IMRT, level Ib-sparing IMRT
- Volunteers
- 398 people
- Sponsor
- Fujian Cancer Hospital
Extremity Orthopedic Surgery
Perioperative Cardiac Troponin Levels in Healthy Adults
This study will determine the extent of high-sensitivity cardiac troponin (hs-cTn) release in patients without cardiac risk factors undergoing extremity orthopedic surgery.
- Trial name
- NCT02394288
- Testing
- Extremity orthopedic or trauma surgery
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Postoperative Ileus, Colorectal Surgery
Prucalopride in Postoperative Ileus
Postoperative ileus (POI) refers to the period of gut dysmotility that occurs after abdominal surgery. Patients with POI are unable to eat, suffer ongoing nausea and vomiting, are unable to open their bowels and have a prolonged…
- Conditions
- Postoperative Ileus, Colorectal Surgery, Postoperative Complications
- Trial name
- NCT02947269
- Testing
- Prucalopride
- Where
- New Zealand
- Volunteers
- 150 people
- Sponsor
- University of Auckland, New Zealand
Microcirculation
Imaging Microcirculation and Gross Hemodynamics in Elective Colorectal Surgery
Rationale: The interaction between macro and microcirculation remains uncertain. Microvascular alterations can occur when systemic hemodynamic parameters are within an acceptable range.
- Trial name
- IMAGES (NCT02688946)
- Testing
- Not provided
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- St. Antonius Hospital
Acute Pain
Effect of Rectus Sheath Block on Diaphragmatic Function After Elective Upper Abdominal Surgery
This study will be undertaken to investigate the respiratory and analgesic effects of ultrasound guided rectus sheath block analgesia after elective abdominal surgery with midline incision.
- Trial name
- Rectus (NCT03725527)
- Testing
- Rectus Sheath Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Fraility, Anxiety, Preoperative
The Relationship Between Preoperative Anxiety Level and Frailty Score in Elderly Patients Scheduled for Elective Hip Arthroplasty: A Prospective Observational Study
Frailty is a state of vulnerability resulting from decreased physiological reserve across multiple organ systems, impairing an individual's ability to withstand stressors.
- Conditions
- Fraility, Anxiety, Preoperative, Hip Arthroplasty
- Trial name
- NCT07633483
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Cesarean Section Complications
Optimal Interval Between Consecutive Cesarean Sections
The goal of this observational study is to determine the best time interval between consecutive cesarean sections and compare maternal and neonatal outcomes in women with a history of previous cesarean sections.
- Trial name
- NCT06491368
- Testing
- Cesarean Delivery
- Where
- Egypt
- Volunteers
- 201 people
- Sponsor
- Al-Azhar University
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