Clinical trials: Elective Cesarean Section
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Hypotension Drug-Induced
Different Preloads for Prevention of Hypotension in Patients Undergoing Elective CS Under Intrathecal Anesthesia
The aim of this study was to compare between crystalloid versus crystalloid and colloid combination preloads for prevention of hypotension following intrathecal anaesthesia in patients undergoing elective Caesarean section.
- Trial name
- NCT03465943
- Testing
- Ringer, Voluven
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain
Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Caesarean Section.
ECS is a very common procedure. A 1-year retrospective survey revealed a vast opioid consumption among the new mothers of approximately (mean±SD) 35±25 mg of oral morphine in the first 24 postoperative hours despite a multimodal…
- Trial name
- NCT03068260
- Testing
- Ropivacaine, Saline, Acetaminophen
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Pregnancy, Respiratory Aspiration of Gastric Contents
Gastric Emptying Following an Oral Carbohydrate Load in Women Admitted for Elective Cesarean Delivery
Because of the risk of pulmonary aspiration, patients are asked to comply with the fasting guidelines when they are scheduled for an elective cesarean section.
- Trial name
- NCT03593980
- Testing
- Cranberry juice
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Respiratory Depression
Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-section
The study will examine whether there is a difference in the frequencies of respiratory depression among obese women receiving spinal anesthesia combined with opioids compared to women with normal BMI.
- Trial name
- NCT02819661
- Testing
- SOMNOTOUCH RESP, Caesarean section, Spinal anesthesia with intrathecal morphine
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pain Management in Adult Females in Child Bearing Period Aging From 20 to 45 Years Who Are Scheduled for Elective Cesarean Section
Intrathecal Dexmedetomidine Versus Transversus Abdominus Plane Block (TAP) for Postoperative Analgesia After Cesarean Section.
Spinal anesthesia is the most commonly used technique for lower abdominal surgeries as it is very economical and easy to administer.
- Trial name
- NCT04969705
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postpartum Hemorrhage
Carbetocin at Elective Cesarean Delivery Part 4
PostPartum hemorrhage (PPH) is a major cause of maternal death worldwide. Oxytocin is the most commonly used uterotonic drug to prevent and treat PPH in North America.
- Trial name
- NCT02264769
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Nausea and Vomiting, Postoperative
Impact of Intrathecal vs Intravenous Dexmedetomidine
The purpose of this research is to evaluate the impact of intrathecal dexmedetomidine in comparison with intravenous route in patients undergoing cesarean section.
- Trial name
- NCT06410365
- Testing
- Dexmedetomidine injection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muhammad Ilyas
Elective Cesarean Delivery
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Elective Cesarean Delivery
Postpartum hemorrhage (PPH) is the leading cause of death related to pregnancy. PPH can lead to blood transfusion, disseminated intravascular coagulation (DIC), hysterectomy, or death.
- Trial name
- NCT06235749
- Testing
- Calcium Gluconate 10%, sodium chloride 0.9%
- Where
- 4 sites in Israel
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Peer Review, Research
Effect of Maternal and Neonatal Oxygenation
Intraoperative supplemental oxygen has been given for most parturients undergoing cesarean section under spinal anesthesia. However, evidences supporting the practice is not clear nowadays, especially for healthy parturients who…
- Trial name
- NCT01530971
- Testing
- Supplemental 3LPM oxygen via canula
- Where
- Thailand
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Breast Feeding, Analgesia
Breastfeeding Evaluation of Puerperal Women Who Had Cesarean Delivery in Our Hospital
İntroduction The World Health Organisation (WHO) and United Nations Children's Fund (UNICEF) recommends that infants are exclusively breastfed for a minimum of 6 months, with continued breastfeeding recommended until child age of…
- Trial name
- NCT06682871
- Testing
- Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Cardiac Arrythmias
Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study
Relationship between carbetocin dose on transmural dispersion of repolarization (TDR).
- Trial name
- CaRDIO (NCT03716076)
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Bowel Dysfunction
Gastrointestinal Activation Post-elective CS (Cesarean Section) :A Comparison of Paula Method to Standard Care
Women generally report discomfort and a delay in GI motility after CS. The Paula method, circular exercises of ring muscles has been shown to increase GI motility. This method had not been studied in women post CS.
- Trial name
- NCT03761147
- Testing
- Paula exercises
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Endometritis
The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section
Objective: To determine the optimal time for intravenous antibiotic prophylaxis administration in pregnant women undergoing elective cesarean section to minimize postpartum infectious complication for both the mother \& neonate.
- Trial name
- NCT02742948
- Testing
- ceftriaxone
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Partum Hemorrhage
Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
The goal of this study is to compare 2 medications that are commonly used to prevent excess uterine bleeding (postpartum hemorrhage, or PPH) following cesarean delivery (CD), oxytocin and carbetocin.
- Trial name
- NCT06333340
- Testing
- Oxytocin, Carbetocin
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Painrelief, Postoperative
Rectal Versus Intramuscular Diclofenac for Pain Relief Following Caesarean Section
Caesarean section (CS) is one of the commonest major Obstetric surgeries worldwide and its rate has markedly increased globally.
- Trial name
- NCT06845930
- Testing
- Rectal Diclofenac, Intramuscular diclofenac
- Where
- Nigeria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assumpta Nnenna Nweke
Cesarean Section Complications
Outcomes of Early Versus Delayed Oral Feeding After Cesarean Section in Korle-bu Teaching Hospital
study compares the outcomes of feeding mothers early (4 hours ) after cesarean section compared to delayed feeding (on post operation day 1) in terms of gastrointestinal function and maternal satisfaction with the feeding…
- Trial name
- NCT03070795
- Testing
- early feeding, delayed feeding
- Where
- Ghana
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Pain, Acute
Intrathecal Midazolam, Fentanyl and Nalbuphine as Adjuvants to Bupivacaine in Spinal Anesthesia for Cesarean Section
The main limitations of spinal anesthesia are its short duration of action and do not provide prolonged postoperative analgesia when it is performed only with local anesthetics.
- Trial name
- NCT04932083
- Testing
- Bupivacaine, Fentanyl, Nalbuphine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University
Outpatient Care
Outpatient Care for Multiparas After Elective Cesarean Section: an Observational Study
The purpose of the study is to evaluate whether outpatient cesarean section can be performed in multiparous women without significant decrease in the parents' sense of security .
- Trial name
- NCT01921465
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
IUD Insertion Complication
Role of Vaginal Misoprostol Prior to IUCD Insertion in Women Who Delivered Only by Elective Caesarean Section.
Role of vaginal misoprostol prior to IUCD insertion in women who delivered only by elective caesarean section.
- Trial name
- NCT03939663
- Testing
- misoprostol
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ain Shams University