Clinical trials: Elective Intubation
Premedication, Endotracheal Intubation
Premedication Trial for Tracheal Intubation of the NEOnate
Multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil" as a premedication prior to endotracheal intubation of the neonate.
- Trial name
- PRETTINEO (NCT01490580)
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 6 sites in France
- Volunteers
- 173 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Laryngoscopy, Anesthesic Aduction
Comparison Between the Neuromuscular Blockade Onset Monitoring and the Expectation of a Fixed Delay After Curarization on the Quality of Laryngoscopy During Intubation in Elective Surgery (MONITURARE)
During anesthetic induction, the relevance of neuromuscular blockade (NMB) onset monitoring cannot be asserted and its superiority over waiting for a fixed delay (corresponding to pharmacokinetic knowledge of the neuromuscular…
- Conditions
- Laryngoscopy, Anesthesic Aduction, Neuromuscular Blockade, Monitoring
- Trial name
- MONITURARE (NCT03981042)
- Testing
- Monitoring
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Poitiers University Hospital
Morbid Obesity, Airway Complication of Anesthesia
Evaluation of SaCo Videolaryngeal Mask Airway in Morbidly Obese
SaCo videolaryngeal mask airway is a novel third generation supraglottic device allowing for continuous observation of entrance to larynx via inserted in special channel videoscope connected with cable with external monitor.
- Conditions
- Morbid Obesity, Airway Complication of Anesthesia, Intubation Complication, Intubation; Difficult or Failed
- Trial name
- NCT05680909
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Video Laryngoscope, Double Lumen Tube Intubation
C-MAC Blade D Video Vs Macintosh Laryngoscope for Double Lumen Tube Insertion
The goal of this clinical trial is to know which type of laryngoscope is better for Double Lumen Tube (DLT) insertion, in participants undergoing elective thoracic surgeries.
- Conditions
- Video Laryngoscope, Double Lumen Tube Intubation, Elective Thoracic Surgery
- Trial name
- DLT (NCT06759038)
- Testing
- C-MAC blade D video laryngoscope, Macintosh Laryngoscope
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Neonates, Infants Aged 0 Days to 12 Months Scheduled for Elective Surgery
Upper Airway Ultrasound to Predict Difficult Laryngoscopy in Neonates and Infants
Upper airway ultrasound (UA-US) has been utilized in adults to predict difficult laryngoscopy (Cormick-Lehane view 3 or 4) and difficult tracheal intubation (DTI) (≥3 intubation attempts) and with moderate-to-high sensitivity and…
- Trial name
- NCT07444528
- Testing
- Upper airway ultrasound
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Airway Management, Intubation, Endotracheal
Two Video Laryngoscopes (Laringocel® and C-MAC®) for First-Attempt Intubation in Adults Undergoing Elective Surgery
This study will test two video laryngoscopes that help doctors place a breathing tube during surgery. A breathing tube is needed for people who receive general anesthesia so they can breathe safely.
- Trial name
- LARINGOCOL (NCT07239141)
- Testing
- Laringocel® videolaryngoscope, C-MAC® D-Blade videolaryngoscope
- Where
- Colombia
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Mario Zamudio
Flexible Fiberoptic Bronchoscopy Versus Flexible Intubation Video Endoscope FIVE in Obese Patients
Comparison of Endotracheal Intubation Using Flexible Fiberoptic Bronchoscopy Versus Flexible Intubation Video Endoscope (FIVE) in Obese Patients Undergoing Elective Surgeries Under General Anesthesia: A Randomized Controlled Trial
Tracheal intubation is one of the most common medical procedures performed in hospitals. On one hand, it is highly successful and easy to perform using a rigid laryngoscope.
- Trial name
- NCT03423563
- Testing
- Flexible fiberoptic bronchoscopy, Fexible intubation video endoscopy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tracheal Intubation
ILMA Fastrach Versus I-gel for Fiberoptic Tracheal Intubation
We evaluate feasibility of fiberoptic intubation through the "ILMA Fastrach" vs the "i-gel". Both are airway devices to be introduced in the mouth we the possibility to ventilate the patient and furthermore to be a guide to…
- Trial name
- NCT00888875
- Testing
- i-gel, ILMA
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cholecystitis, Choledocholithiasis
Laryngeal Mask Airway Supreme Versus the Tracheal Tube as an Airway Device in Elective Laparoscopic Cholecystectomy
We hypothesise that the use of the LMA-Supreme provides greater ease of insertion and reduced haemodynamic variability during insertion compared to the tracheal tube, whilst still maintaining a patent airway to facilitate…
- Trial name
- NCT02037958
- Testing
- Laryngeal Mask Airway-Supreme, Endotracheal Tube
- Where
- Singapore
- Volunteers
- 76 people
- Sponsor
- Changi General Hospital
Awake Fiberoptic Intubation
A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation for Elective Awake Fiberoptic Intubation
The purpose of this study is to evaluate the safety and efficacy of dexmedetomidine versus placebo used for sedation during elective awake fiberoptic intubation.
- Trial name
- NCT00383890
- Testing
- Dexmedetomidine HCL Injection
- Where
- 17 sites in United States
- Volunteers
- 124 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Elective Surgical Procedure, ASA Physical Status I
Effectiveness of Intranasal Dexmedetomidine Premedication in Child Intubation
The purpose of this study is to find out if a medicine called dexmedetomidine, given as a nasal spray, can help patients stay calm and comfortable before having a breathing tube placed (intubation).
- Conditions
- Elective Surgical Procedure, ASA Physical Status I, ASA Physical Status II
- Trial name
- NCT06991647
- Testing
- Intranasal dexmedetomidine, 0.9% NaCl solution
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation and Bolus Maintenance in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07746726
- Testing
- HRS-9190, Rocuronium
- Where
- 2 sites in China
- Volunteers
- 320 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Impaired Airway Clearance
Fospropofol for Sedation During Elective Awake Intubation
Patients scheduled for awake fiberoptic intubation (AFI) because of potential difficult airway will be consented prior to intubation ASA Physical Status classification and history of difficult intubation will be recorded at…
- Trial name
- NCT01289483
- Testing
- fospropofol
- Where
- United States
- Sponsor
- The Cleveland Clinic
Elective Surgery, Target Controlled Infusion (TCI)
EC50 of Ciprofol Combined With Remifentanil for Inhibiting Tracheal Responses in Patients Undergoing Gynecological Surgery: a Two-phase Up-and-down Sequential Allocation Study
1. The combined induction of intubation with propofol and remifentanil is widely used in clinical anesthesia, primarily through a single intravenous injection.
- Conditions
- Elective Surgery, Target Controlled Infusion (TCI), Noxious Stimuli, Tracheal Intubation Stimulation
- Trial name
- EC50 via TCI (NCT07462949)
- Testing
- Cipofol combined with remifentanil administered via target-controlled infusion
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Intubation
First Attempt Intubation Rate With Airtraq vs Macintosh Direct Laryngoscope
In recent decades, numerous videolaryngoscopes have been introduced to facilitate tracheal intubation. However, it remains unclear whether videolaryngoscope will increase the successful tracheal intubation compared with usual…
- Trial name
- FAIRAiM (NCT03887897)
- Testing
- Tracheal Intubation
- Where
- Hong Kong
- Volunteers
- 1,586 people
- Sponsor
- Chinese University of Hong Kong
Paediatric Airway
Comparison of Time Taken for Intubation and Cormack Lehane View Between C-Mac With Glidescope Video Laryngoscopy in Paediatric Patients
This study compares the time taken to intubate between Cmac video laryngoscopy with Glidescope video laryngoscopy in paediatric patients aged 3-12 years old.
- Trial name
- NCT04145089
- Testing
- Glidescope video laryngoscopy/ C-MAC video laryngoscopy
- Where
- Malaysia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Elective Surgery Requiring Tracheal Intubation Using an Oral Tracheal Tube
Blind Intubation Through The Self-Pressurised Disposable Air-Q Laryngeal Intubation Mask: An International Multicentre Trial
The disposable Air-Q self-inflating laryngeal intubation mask (Air-Q, Mercury Medical, Clearwater, FL, USA) is an extra-glottic airway device which enables blind intubation with a tracheal tube.
- Trial name
- NCT01906060
- Testing
- Air-Q Intubation Laryngeal Mask
- Where
- 3 sites in Poland, Switzerland
- Volunteers
- 1,000 people
- Sponsor
- University of Zurich
Tracheal Intubation
Assessment of the the ETView Double-lumen Tube
The double tube ETView is particularly innovative as it includes an integrated optical fiber to visualize the carena. This study aims to verify if if its use avoids the requirement of a fibreoptic bronchoscopy.
- Trial name
- ETView1 (NCT02040961)
- Testing
- ETView Double-Lumen Tube
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Hopital Foch
Cervical Spine Instability
Comparing Ease of Endotracheal Intubation Using C Blade and D Blade of CMAC Videolaryngoscope in Patients Undergoing Elective Cervical Spine Surgery
This study was done to compare the ease of tracheal intubation using the conventional C blade and the D blade of CMAC videolaryngoscope in patients undergoing cervical spine surgery.
- Trial name
- NCT05561231
- Testing
- Intubation with C blade, Intubation with D blade
- Where
- India
- Volunteers
- 68 people
- Sponsor
- King Edward Memorial Hospital, Mumbai
Endotracheal Intubation
Comparing Endotracheal Tube Cuff Pressure in Laparoscopic Abdominal Surgery: Saline vs. Air Inflation
In this study, the investigators aim to compare the incidence of cuff pressure increase between endotracheal tubes inflated with air or saline during elective laparoscopic abdominal surgery under general anesthesia with N2O.
- Trial name
- NCT06089187
- Testing
- Endotracheal intubation using an endotracheal tube with cuff inflated with air, Endotracheal intubation using an endotracheal tube with cuff inflated with saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University