Clinical trials: Elective Laparoscopic Cholecystectomy
Elective Laparoscopic Cholecystectomy, Sevoflurane Anesthesia
Pregabalin Reduce the Sevoflurane Requirement
Preoperative administration of pregabalin would reduce the end tidal concentration of sevoflurane during laparoscopic cholecystectomy with added beneficial improving of the quality of postoperative analgesia.
- Trial name
- NCT01571804
- Testing
- pregabalin
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Mansoura University
GIT Function, Cholecystectomy, Laparoscopic
Dexamethasone, Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn the effect of Dexamethasone and Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy What medical problems do…
- Conditions
- GIT Function, Cholecystectomy, Laparoscopic, Dexamethasone, Dexmedetomidine
- Trial name
- vomiting (NCT07329933)
- Testing
- Dexamethasone, Dexmedetomidine, Dexamethasone and dexmedetomidine
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Benha University
Elective Laparoscopic Cholecystectomy
"Impact of NOciception Level (NOL) Index Intraoperative Guidance of REmifentanil Administration on Opioid Consumption and QoR in Ambulatory Patients Undergoing LAparoscopic Cholecystectomy."
Background: Laparoscopic cholecystectomy is a common surgical procedure which constitutes the standard treatment for symptomatic gallbladder disease.
- Trial name
- NORELACs (NCT07810894)
- Testing
- Remifentanil titration based on Nociception Level Monitor, Remifetanil guided by vital parameters and clinical assessment
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Svendborg Hospital
Postoperative Nausea and Vomiting (PONV), Heart Rate Variability (HRV)
Predictive Role of HRV for PONV in Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV) are among the most common complications following general anesthesia (GA), significantly affecting patient comfort and recovery.
- Conditions
- Postoperative Nausea and Vomiting (PONV), Heart Rate Variability (HRV), Laparoscopic Cholecystectomy
- Trial name
- NCT06948708
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Pain, Postoperative, Pain, Acute
A Study of the Effects of Intravenous Magnesium Sulphate on Anaesthesia and Analgesia in Elective General Surgery Patients
The aim of this double-blind randomized study will be to evaluate the effect an intravenous infusion of magnesium has on recovery outcomes after elective laparoscopic cholecystectomy
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Nociceptive, Analgesia
- Trial name
- NCT05598307
- Testing
- magnesium bolus followed by normal saline infusion, magnesium bolus followed by magnesium infusion, normal saline bolus followed by normal saline infusion
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital
Cholelithiasis
Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy
This prospective observational study will examine how electrosurgical activation patterns during elective laparoscopic cholecystectomy are associated with surgeon experience and intraoperative difficulty.
- Trial name
- ELECTRO-LC (NCT07888491)
- Testing
- Elective laparoscopic cholecystectomy
- Where
- Croatia
- Volunteers
- 165 people
- Sponsor
- University Hospital of Split
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block Versus Combined Subcostal TAP and Recto-Intercostal Fascial Plane Block for Analgesia After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period.
- Trial name
- NCT07869316
- Testing
- Subcostal Transversus Abdominis Plane Block, Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Cholecystitis, Choledocholithiasis
Laryngeal Mask Airway Supreme Versus the Tracheal Tube as an Airway Device in Elective Laparoscopic Cholecystectomy
We hypothesise that the use of the LMA-Supreme provides greater ease of insertion and reduced haemodynamic variability during insertion compared to the tracheal tube, whilst still maintaining a patent airway to facilitate…
- Trial name
- NCT02037958
- Testing
- Laryngeal Mask Airway-Supreme, Endotracheal Tube
- Where
- Singapore
- Volunteers
- 76 people
- Sponsor
- Changi General Hospital
Transversus Abdominis Plane Block, External Oblique Block
Analgesic Efficacy of Transversus Abdominis Plane Block Versus External Oblique Block in Patients Undergoing Elective Laparoscopic Cholecystectomy
Postoperative pain management is a critical aspect of recovery following laparoscopic cholecystectomy, a commonly performed procedure for symptomatic gallbladder disease.
- Conditions
- Transversus Abdominis Plane Block, External Oblique Block, Laparoscopic Cholecystectomy
- Trial name
- NCT06707324
- Testing
- drug injected between the rectus abdominis muscle and the transversus abdominis muscle, drug injected in the external oblique intercostal plane on both sides
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Dexmedetomidine, Magnesium Sulfate
Dexmedetomidine Versus Magnesium Sulfate as Adjuvants to Intraperitoneal Bupivacaine for Postoperative Analgesia After Elective Laparoscopic Cholecystectomy
This study aimed to assess the efficiency of dexmedetomidine against magnesium sulfate as adjuvants to intraperitoneal bupivacaine for postoperative analgesia in individuals having elective laparoscopic cholecystectomy.
- Conditions
- Dexmedetomidine, Magnesium Sulfate, Adjuvants, Intraperitoneal Bupivacaine
- Trial name
- NCT06879288
- Testing
- Bupivacaine, Dexmedetomidine, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Opioid-Free Anesthesia, Elective Laparoscopic Cholecystectomy
Effect of Opioid-Free Anesthesia (OFA) on Postoperative Pain and Perioperative Nausea and Vomiting in Elective Laparoscopic .
1. To evaluate the efficacy of a standardized multimodal Opioid Sparing (OS) protocol versus conventional opioid-based analgesia in reducing acute postoperative 2.
- Trial name
- OFA (NCT07306910)
- Testing
- opoid free anesthesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preoperative Anxiety, Postoperative Pain
Prediction of Postoperative Pain Using Venous Cannulation Pain and Preoperative Anxiety Scores
Postoperative pain remains a significant clinical problem affecting recovery, mobilization, and patient satisfaction after surgery.
- Trial name
- NCT07451925
- Testing
- APAIS Assessment
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
General Anesthesia, Elective Laparoscopic Cholecystectomy
The Effect of Positive End-Expiratory Pressure Levels on Perfusion Index and Neurocognitive Functions in Geriatric Patients
With the increasing geriatric population, age-related physiological changes and common comorbidities increase the risk of surgical and anesthesia-related complications in this patient group.
- Trial name
- NCT07505550
- Testing
- PEEP levels
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ankara City Hospital Bilkent
Cardiac Arrhythmia, Anesthesia
The Effects of Low-Flow and Normal-Flow Sevoflurane Anesthesia on Frontal QRS-T Angle and TP-e Interval
Laparoscopic cholecystectomy procedures involve pneumoperitoneum and volatile anesthetics, both of which can significantly influence cardiovascular physiology and autonomic balance.
- Trial name
- NCT07571980
- Testing
- low flow anesthesia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Cholecystitis
Prophylactic TAP Block in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the gold standard for cholelithiasis, yet postoperative pain remains a clinical challenge. Ultrasound-guided transversus abdominis plane (TAP) block has been proposed as an effective analgesic…
- Trial name
- NCT07871617
- Testing
- Analgesic, Analgesic transversus abdominal plane blockade (Bupivacaine)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Incisional Hernia
Umbilical vs Paraumbilical Trocar Placement in Patients Undergoing Elective Laparoscopic Cholecystectomy
The aim of this study will be to assess the incisional hernia rate of umbilical or paraumbilical port 12 months after laparoscopic cholecystectomy.
- Trial name
- NCT04347642
- Testing
- Umbilical port placement, Paraumbilical port placement
- Where
- 2 sites in Mexico, Spain
- Volunteers
- 180 people
- Sponsor
- Hospital General Universitario Elche
Elective Laparoscopic Cholecystectomy
The Effect of Respiratory Exercises on Abdominal Distension in Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is the first-line treatment for symptomatic gallstones. Pneumoperitoneum is the process of expanding the abdominal cavity during the surgical procedure by introducing CO2 gas into the abdomen to widen…
- Trial name
- NCT06069557
- Testing
- Respiratory exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Gallstones, Cholelithiasis
RCT: Multi-modal Analgesia for Laparoscopic Cholecystectomy
Analgesic efficacy of multi-modal analgesia is superior to standard analgesia for patients undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
- Conditions
- Gallstones, Cholelithiasis, Pain
- Trial name
- LapChole (NCT01972620)
- Testing
- Bupivacaine
- Where
- Serbia
- Volunteers
- 63 people
- Sponsor
- Klinicki Centar Vojvodine
Hemodynamic Monitoring, Laryngeal Mask Success Rate
Comparison of I-gel and SaCoVLM in Laparoscopic Cholecystectomy
This prospective observational study aims to compare the ventilation performance and safety of the i-gel and SaCoVLM supraglottic airway devices in adult patients undergoing elective laparoscopic cholecystectomy.
- Conditions
- Hemodynamic Monitoring, Laryngeal Mask Success Rate, End Tidal Carbon Dioxide
- Trial name
- NCT07692139
- Volunteers
- 80 people
- Sponsor
- Samsun University
Shoulder Pain, Nausea
Risk Factors for Shoulder Pain and Emesis After Laparoscopic Cholecystectomy
Risk factors for postoperative shoulder pain after laparoscopic cholecystectomy were not clear. Moreover, risk factors for postoperative emesis specially for this surgery were not detailed and accurate.
- Conditions
- Shoulder Pain, Nausea, Vomiting
- Trial name
- NCT01095536
- Where
- Taiwan
- Volunteers
- 380 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan