Clinical trials: Elective Laparoscopic Cholecystectomy
Opioid-Free Anesthesia, Elective Laparoscopic Cholecystectomy
Effect of Opioid-Free Anesthesia (OFA) on Postoperative Pain and Perioperative Nausea and Vomiting in Elective Laparoscopic .
1. To evaluate the efficacy of a standardized multimodal Opioid Sparing (OS) protocol versus conventional opioid-based analgesia in reducing acute postoperative 2.
- Trial name
- OFA (NCT07306910)
- Testing
- opoid free anesthesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Elective Laparoscopic Cholecystectomy
The Effect of Respiratory Exercises on Abdominal Distension in Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is the first-line treatment for symptomatic gallstones. Pneumoperitoneum is the process of expanding the abdominal cavity during the surgical procedure by introducing CO2 gas into the abdomen to widen…
- Trial name
- NCT06069557
- Testing
- Respiratory exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Prophylactic Salpingectomy, Opportunistic Salpingectomy
Salpingectomy at the Time of Elective Laparoscopic Cholecystectomy (SaLCHE)
Prophylactic salpingectomy (also called opportunistic, risk-reducing or incidental salpingectomy) has been advocated at the time of gynecologic surgery to reduce the risk of serous ovarian cancer.
- Conditions
- Prophylactic Salpingectomy, Opportunistic Salpingectomy, Laparoscopic Cholecystectomy
- Trial name
- SaLCHE (NCT03171467)
- Testing
- Salpingectomy
- Where
- 6 sites in Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Hemodynamic Monitoring, Laryngeal Mask Success Rate
Comparison of I-gel and SaCoVLM in Laparoscopic Cholecystectomy
This prospective observational study aims to compare the ventilation performance and safety of the i-gel and SaCoVLM supraglottic airway devices in adult patients undergoing elective laparoscopic cholecystectomy.
- Conditions
- Hemodynamic Monitoring, Laryngeal Mask Success Rate, End Tidal Carbon Dioxide
- Trial name
- NCT07692139
- Volunteers
- 80 people
- Sponsor
- Samsun University
Pain, Postoperative, Pain, Acute
A Study of the Effects of Intravenous Magnesium Sulphate on Anaesthesia and Analgesia in Elective General Surgery Patients
The aim of this double-blind randomized study will be to evaluate the effect an intravenous infusion of magnesium has on recovery outcomes after elective laparoscopic cholecystectomy
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Nociceptive, Analgesia
- Trial name
- NCT05598307
- Testing
- magnesium bolus followed by normal saline infusion, magnesium bolus followed by magnesium infusion, normal saline bolus followed by normal saline infusion
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital
Hypotension, Anesthesia, General
Internal Jugular Vein Collapsibility Index for Predicting Post-Induction Hypotension
This study aims to investigate whether the Internal Jugular Vein Collapsibility Index (IJV-CI), measured via ultrasonography, can predict hypotension (low blood pressure) that occurs after the induction of general anesthesia.
- Conditions
- Hypotension, Anesthesia, General, Cholecystectomy, Laparoscopic
- Trial name
- IJV-CI (NCT07565025)
- Testing
- IJV-CI Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- University of Gaziantep
Laparoscopic Cholecystectomy, Postoperative Quality of Recovery
Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is one of the most commonly performed abdominal surgical procedures worldwide. Although the widespread implementation of Enhanced Recovery after Surgery (ERAS) protocols has improved perioperative…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Quality of Recovery, Preoperative Anxiety, Postoperative Sleep Quality
- Trial name
- MEL-REC (NCT07553143)
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine)
- Where
- Bangladesh
- Volunteers
- 84 people
- Sponsor
- Armed Forces Medical Institute Bangladesh
Quality of Recovery, Pain, Postoperative
Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia
The aim of this study is to compare the quality of recovery from general anesthesia and surgery using the quality of recovery 15 item scale (QoR-15) for participant's receiving opioid-Sparing anesthesia with those receiving…
- Conditions
- Quality of Recovery, Pain, Postoperative, Elective Laparoscopic Cholecystectomy
- Trial name
- NCT06343753
- Testing
- Opioid free analgesia, Opioid based Anesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Spinal Anesthesia, General Anesthesia
Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy
The purpose of the study is to assess whether spinal anesthesia is or not superior to the standard general anesthesia for fit patients undergoing laparoscopic cholecystectomy.
- Conditions
- Spinal Anesthesia, General Anesthesia, Postoperative Pain
- Trial name
- SALC (NCT00492453)
- Testing
- laparoscopic cholecystectomy
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Laparoscopic Cholecystectomy
Nerve Blocks vs Local Injections for Post-op Pain Prevention in Laparoscopic Cholecystectomy in Children
The objective of this study is to compare transversus abdominis plane (TAP) blocks to local wound infiltration (LWI) in terms of postoperative pain control in pediatric patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT03022279
- Testing
- TAP Blocks, local wound infiltration
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Brian Wallace Gray
Gallstones
Compliance of Clinical Pathways in Elective Laparoscopic Cholecystectomy: Evaluation of Different Implementation Methods
Compliance to the clinical pathway, postoperative complication and total cost of the hospitalisation of patients undergoing elective cholecystectomy for symptomatic cholecystolithiasis were collected over two different periods…
- Trial name
- NCT02667249
- Testing
- clinical pathway
- Volunteers
- 241 people
- Sponsor
- University Hospital Tuebingen
Postoperative Pain
Analgesic Efficacy of Quadratus Lumborum, Paravertebral Blocks
This trial is a prospective, randomized, single-center, single blinded-analysis trial, the objective of which is compare the postoperative analgesia efficacy of Quadratus lumborum II, Quadratus Lumborum III and Paravertebral…
- Trial name
- NCT05943015
- Testing
- Quadratus Lumborum Block II, Patient controlled intravenous analgesia, Quadratus Lumborum Block III
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Incisional Hernia
Umbilical vs Paraumbilical Trocar Placement in Patients Undergoing Elective Laparoscopic Cholecystectomy
The aim of this study will be to assess the incisional hernia rate of umbilical or paraumbilical port 12 months after laparoscopic cholecystectomy.
- Trial name
- NCT04347642
- Testing
- Umbilical port placement, Paraumbilical port placement
- Where
- 2 sites in Mexico, Spain
- Volunteers
- 180 people
- Sponsor
- Hospital General Universitario Elche
Laparoscopic Cholecystectomy, Postoperative Pain
RIPB Versus EOIPB for Pain Control After Laparoscopic Cholecystectomy
This prospective observational study aims to compare the effects of bilateral ultrasound-guided recto-intercostal plane block(RIPB) and bilateral ultrasound-guided external oblique intercostal plane block(EOIPB) on postoperative…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Postoperative Analgesia
- Trial name
- RIPB-EOIPB (NCT07607262)
- Testing
- Bilateral Ultrasound-Guided Recto-Intercostal Plane Block, Bilateral Ultrasound-Guided External Oblique Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cholelithiases
Enhanced Recovery After Cholecystectomy
this study will be conducted involving patients of all genders between the ages of 20 and 60 years who will undergo elective laparoscopic cholecystectomy for uncomplicated symptomatic gallstone disease.
- Trial name
- NCT06339437
- Testing
- ERAS Protocol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Cholelithiasis
Cholecystectomy vs EUS-guided GBD With Stone Removal
In this new era of less invasive procedures, the indications for endoscopic ultrasound (EUS)-guided gallbladder drainage (GBD) are rapidly expanding.
- Trial name
- NCT06038201
- Testing
- LAMS placement for cholecystostomy, Laparoscopic cholecystectomy
- Where
- Ecuador
- Volunteers
- 56 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Gall Stone, Gallbladder Inflammation
Benchmarks in Elective Laparoscopic Cholecystectomy
The aim of this observational cohort study is to define peri- and postoperative reference values for elective laparoscopic cholecystectomy, using the achievable benchmarks of care methodology (ABC™).
- Conditions
- Gall Stone, Gallbladder Inflammation, Gall Bladder Pain, Gallstone
- Trial name
- NCT06692517
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 60,000 people
- Sponsor
- Region Östergötland
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block Versus Combined Subcostal TAP and Recto-Intercostal Fascial Plane Block for Analgesia After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period.
- Trial name
- NCT07869316
- Testing
- Subcostal Transversus Abdominis Plane Block, Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Cholelithiasis
Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy
This prospective observational study will examine how electrosurgical activation patterns during elective laparoscopic cholecystectomy are associated with surgeon experience and intraoperative difficulty.
- Trial name
- ELECTRO-LC (NCT07888491)
- Testing
- Elective laparoscopic cholecystectomy
- Where
- Croatia
- Volunteers
- 165 people
- Sponsor
- University Hospital of Split
Gallstone Disease
Multimedia Informed Consent & PROMs in Laparoscopic Cholecystectomy
Collection of PROMs (Patient Reported Outcome Measures) data from patients before and after an operation to remove their gallbladder for the treatment of symptomatic gallstones.
- Trial name
- EPICS (NCT02810860)
- Testing
- Laparoscopic cholecystectomy
- Where
- United Kingdom
- Volunteers
- 349 people
- Sponsor
- Nottingham University Hospitals NHS Trust